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1. Full Text Subgroup analysis of Japanese patients in a phase 3 study of lenvatinib in radioiodine‐refractory differentiated thyroid cancer
by Kiyota, Naomi and Schlumberger, Martin and Muro, Kei and Ando, Yuichi and Takahashi, Shunji and Kawai, Yasukazu and Wirth, Lori and Robinson, Bruce and Sherman, Steven and Suzuki, Takuya and Fujino, Katsuki and Gupta, Anubha and Hayato, Seiichi and Tahara, Makoto
Cancer Science, ISSN 1347-9032, 12/2015, Volume 106, Issue 12, pp. 1714 - 1721
Lenvatinib significantly prolonged progression‐free survival (PFS) versus placebo in patients with radioiodine‐refractory differentiated thyroid cancer... 
Japanese patients | thyroid cancer | lenvatinib | progression‐free survival | treatment efficacy | Treatment efficacy | Lenvatinib | Thyroid cancer | Progression-free survival | ANGIOGENESIS | EFFICACY | SAFETY | progression-free survival | SORAFENIB | ANTITUMOR ACTIVITIES | RENAL-CELL CARCINOMA | E7080 | THERAPY | ONCOLOGY | DOUBLE-BLIND | INHIBITOR | Carcinoma - drug therapy | Iodine Radioisotopes | Thyroid Neoplasms - mortality | Humans | Middle Aged | Kaplan-Meier Estimate | Carcinoma - mortality | Phenylurea Compounds - therapeutic use | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Quinolines - pharmacokinetics | Disease-Free Survival | Asian Continental Ancestry Group | Thyroid Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Aged | Antineoplastic Agents - pharmacokinetics | Phenylurea Compounds - pharmacokinetics | Quinolines - therapeutic use | Analysis | Oncology, Experimental | Clinical trials | Development and progression | Research | Cancer | Body weight | Metastasis | Survival | Studies | Medical prognosis | Fibroblasts | Population | Safety | Vascular endothelial growth factor | Thyroid | Proteinuria | Tumors | Original
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2. Full Text Fatal Cardiac Hemochromatosis in a Patient with Hereditary Spherocytosis
by Fujino, Takeo and Inoue, Shujiro and Katsuki, Shunsuke and Higo, Taiki and Ide, Tomomi and Oda, Yoshinao and Tsutsui, Hiroyuki
International Heart Journal, ISSN 1349-2365, 2018, Volume 59, Issue 2, pp. 427 - 430
A 31-year-old man was admitted to our hospital with atrial tachycardia and cardiogenic shock. He had been diagnosed with hereditary spherocytosis (HS) during... 
Heart failure | Cardiogenic shock | Atrial tachycardia | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | IRON-OVERLOAD | Cardiac arrhythmia | Hemochromatosis | Arrhythmia | Coexistence | Congestive heart failure | Patients | Heterozygosity | Tachycardia | Biopsy | Hereditary spherocytosis | Fibrosis | Point mutation | Chelation | HFE protein | Children | Ventricle | Spherocytosis
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3. Full Text Trastuzumab in combination with docetaxel/cisplatin/S-1 (DCS) for patients with HER2-positive metastatic gastric cancer: feasibility and preliminary efficacy
by Mitsui, Yasuhiro and Sato, Yasushi and Miyamoto, Hiroshi and Fujino, Yasuteru and Takaoka, Toshi and Miyoshi, Jinsei and Kagawa, Miwako and Ohnuma, Hiroyuki and Hirakawa, Masahiro and Kubo, Tomohiro and Osuga, Takahiro and Sagawa, Tamotsu and Sato, Yasuhiro and Takahashi, Yasuo and Katsuki, Shinich and Okuda, Toshinori and Takimoto, Rishu and Kobune, Masayoshi and Nobuoka, Takayuki and Hirata, Koichi and Kato, Junji and Takayama, Tetsuji
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 8/2015, Volume 76, Issue 2, pp. 375 - 382
We previously reported that a triplet combination of docetaxel, cisplatin, and S-1 (DCS) is active against metastatic gastric cancer with a very high response... 
Medicine & Public Health | Oncology | Cancer Research | Feasibility | Pharmacology/Toxicology | HER2 | Gastric cancer | Trastuzumab | PLUS CISPLATIN | FLUOROURACIL | DOCETAXEL | CHEMOTHERAPY | PHASE-III TRIAL | THERAPY | ONCOLOGY | S-1 | PHARMACOLOGY & PHARMACY | Humans | Middle Aged | Stomach Neoplasms - metabolism | Male | Stomach Neoplasms - pathology | Oxonic Acid - administration & dosage | Stomach Neoplasms - drug therapy | Cisplatin - administration & dosage | Feasibility Studies | Taxoids - administration & dosage | Neoplasm Metastasis | Receptor, Epidermal Growth Factor - metabolism | Antibodies, Monoclonal, Humanized - administration & dosage | Tegafur - administration & dosage | Adult | Female | Aged | Drug Combinations
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4. Full Text Impact of dose interruption on the efficacy of lenvatinib in a phase 3 study in patients with radioiodine-refractory differentiated thyroid cancer
by Tahara, Makoto and Brose, Marcia S and Wirth, Lori J and Suzuki, Takuya and Miyagishi, Hideaki and Fujino, Katsuki and Dutcus, Corina E and Gianoukakis, Andrew
European Journal of Cancer, ISSN 0959-8049, 01/2019, Volume 106, pp. 61 - 68
In the phase 3 tudy of ( 7080) nvatinib in ifferentiated ancer of the hyroid (SELECT), lenvatinib significantly improved efficacy outcomes versus placebo in... 
Thyroid neoplasms | MeSH terms | Lenvatinib | Disease-free survival | E7080 | ONCOLOGY | INHIBITOR | ANTITUMOR ACTIVITIES | Complications and side effects | Care and treatment | Thyroid cancer | Oncology, Experimental | Analysis | Research | Cancer | Interruption | Iodine radioisotopes | Effectiveness | Toxicity | Iodine 131 | Clinical trials | Cancer therapies | Patients | Impact analysis | Confidence intervals | Refractory materials | Drug therapy | Thyroid
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5. Full Text A phase 1 study of lenvatinib, multiple receptor tyrosine kinase inhibitor, in Japanese patients with advanced solid tumors
by Nakamichi, Shinji and Nokihara, Hiroshi and Yamamoto, Noboru and Yamada, Yasuhide and Honda, Kazunori and Tamura, Yosuke and Wakui, Hiroshi and Sasaki, Tatsuya and Yusa, Wataru and Fujino, Katsuki and Tamura, Tomohide
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 12/2015, Volume 76, Issue 6, pp. 1153 - 1161
This phase 1 study aimed to assess the tolerability, safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of lenvatinib capsules in... 
E7080 | Angiogenesis | Medicine & Public Health | Oncology | Cancer Research | Lenvatinib | Phase 1 | Safety | Pharmacology/Toxicology | Japanese | PLACEBO | ONCOLOGY | PHARMACOLOGY & PHARMACY | CANCER | Neoplasms - metabolism | Protein Kinase Inhibitors - pharmacokinetics | Nausea - chemically induced | Area Under Curve | Humans | Japan | Middle Aged | Male | Metabolic Clearance Rate | Treatment Outcome | Thrombocytopenia - chemically induced | Protein Kinase Inhibitors - adverse effects | Neoplasms - drug therapy | Quinolines - pharmacokinetics | Asian Continental Ancestry Group | Neoplasms - ethnology | Phenylurea Compounds - adverse effects | Adult | Female | Phenylurea Compounds - pharmacokinetics | Headache - chemically induced | Quinolines - adverse effects | Hypertension | Tyrosine | Medicine, Experimental | Medical research | Glycoproteins | Tumors | Index Medicus | Original
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6. Full Text Validity and Responsiveness of the Work Functioning Impairment Scale in Workers With Depression
by Tokutsu, Kei and Kawazoe, Shingo and Katsuki, Asuka and Muramatsu, Keiji and Makishima, Misako and Kubo, Tatsuhiko and Yoshimura, Reiji and Matsuda, Shinya and Fujino, Yoshihisa
Journal of Occupational and Environmental Medicine, ISSN 1076-2752, 12/2019, Volume 61, Issue 12, pp. e523 - e527
OBJECTIVE:We aimed to evaluate the convergent validity and responsiveness of the work functioning impairment scale (WFun) in patients with depression, a major... 
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7. Full Text Lenvatinib for anaplastic thyroid cancer
by Tahara, Makoto and Kiyota, Naomi and Yamazaki, Tomoko and Chayahara, Naoko and Nakano, Kenji and Inagaki, Lina and Toda, Kazuhisa and Enokida, Tomohiro and Minami, Hironobu and Imamura, Yoshinori and Sasaki, Tatsuya and Suzuki, Takuya and Fujino, Katsuki and Dutcus, Corina E and Takahashi, Shunji
Frontiers in Oncology, ISSN 2234-943X, 03/2017, Volume 7, p. 25
Lenvatinib has been approved by regulatory agencies in Japan, the United States, and the European Union for treatment of radioiodine-refractory differentiated... 
Clinical trial | Anaplastic thyroid cancer | Lenvatinib | Phase 2 | Tyrosine kinase inhibitor | Care and treatment | Thyroid cancer | Health aspects | Cancer
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8. Full Text Fatal Cardiac Hemochromatosis in a Patient with Hereditary Spherocytosis
by Fujino, Takeo and Inoue, Shujiro and Katsuki, Shunsuke and Higo, Taiki and Ide, Tomomi and Oda, Yoshinao and Tsutsui, Hiroyuki
International Heart Journal, ISSN 1349-2365, 2018
A 31-year-old man was admitted to our hospital with atrial tachycardia and cardiogenic shock. He had been diagnosed with hereditary spherocytosis (HS) during... 
Heart failure | Cardiogenic shock | Atrial tachycardia
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9. Full Text Phase II study of lenvatinib in patients with differentiated, medullary, and anaplastic thyroid cancer: Final analysis results
by Takahashi, Shunji and Kiyota, Naomi and Yamazaki, Tomoko and Chayahara, Naoko and Nakano, Kenji and INAGAKI, LINA and Toda, Kazuhisa and Enokida, Tomohiro and Minami, Hironobu and Imamura, Yoshinori and Sasaki, Tatsuya and Suzuki, Takuya and Fujino, Katsuki and Dutcus, Corina and Tahara, Makoto
Journal of Clinical Oncology, ISSN 0732-183X, 05/2016, Volume 34, Issue 15_suppl, pp. 6088 - 6088
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10. Fatal Cardiac Hemochromatosis in a Patient with Hereditary Spherocytosis
by Fujino, Takeo and Inoue, Shujiro and Katsuki, Shunsuke and Higo, Taiki and Ide, Tomomi and Oda, Yoshinao and Tsutsui, Hiroyuki
International heart journal, 03/2018, Volume 59, Issue 2, p. 427
A 31-year-old man was admitted to our hospital with atrial tachycardia and cardiogenic shock. He had been diagnosed with hereditary spherocytosis (HS) during... 
Hemochromatosis - complications | Humans | Fatal Outcome | Adult | Male | Heart Failure - etiology | Spherocytosis, Hereditary - complications
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11. Full Text Randomized Head-to-Head Comparison of Pitavastatin, Atorvastatin, and Rosuvastatin for Safety and Efficacy (Quantity and Quality of LDL) - The PATROL Trial
by Saku, Keijiro and Zhang, Bo and Noda, Keita and and PATROL Trial Investigators
Circulation Journal, ISSN 1346-9843, 2011, Volume 75, Issue 6, pp. 1493 - 1505
Background: Atorvastatin, rosuvastatin and pitavastatin are available for intensive, aggressive low-density lipoprotein cholesterol (LDL-C)-lowering therapy in... 
Atorvastatin | Pitavastatin | Efficacy | Rosuvastatin | Safety | CAPILLARY ISOTACHOPHORESIS | MULTICENTER | CARDIAC & CARDIOVASCULAR SYSTEMS | HYPERLIPIDEMIA | ATHEROSCLEROSIS | SUBFRACTIONS | HYPERCHOLESTEROLEMIC PATIENTS | PHARMACOKINETICS | DISEASE | INTRAVASCULAR ULTRASOUND | STATIN TREATMENT | Prospective Studies | Heptanoic Acids - therapeutic use | Humans | Middle Aged | Male | Heptanoic Acids - adverse effects | Hypercholesterolemia - drug therapy | Patient Selection | Time Factors | Pyrroles - adverse effects | Cholesterol, LDL - blood | Female | Pyrroles - therapeutic use | Hypercholesterolemia - blood | Japan | Rosuvastatin Calcium | Treatment Outcome | Biomarkers - blood | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Analysis of Variance | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Pyrimidines - adverse effects | Sulfonamides - adverse effects | Aged | Fluorobenzenes - adverse effects | Quinolines - therapeutic use | Fluorobenzenes - therapeutic use | Quinolines - adverse effects
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12. Full Text Factors Associated with Variation in Utility Scores among Patients with Prostate Cancer
by Shimizu, Fumitaka and Fujino, Katsuki and Ito, Yoichi M and Fukuda, Takashi and Kawachi, Yoshio and Minowada, Shigeru and Fujime, Makoto and Ohashi, Yasuo
Value in Health, ISSN 1098-3015, 2008, Volume 11, Issue 7, pp. 1190 - 1193
Abstract Objective We aimed to assess the effects of age, comorbidity, and disease-specific functions on utility scores derived from three methods on prostate... 
Internal Medicine | disease-specific functions | quality of life | utilities | prostatic neoplasms | disease‐specific functions | Utilities | Disease-specific functions | Prostatic neoplasms | Quality of life | PREFERENCES | MEN | HEALTH CARE SCIENCES & SERVICES | HEALTH POLICY & SERVICES | OUTCOMES | HEALTH STATES | Health Surveys | Humans | Middle Aged | Intestinal Diseases - psychology | Aged, 80 and over | Quality of Life | Male | Aged | Prostatic Neoplasms - complications | Prostatic Neoplasms - psychology | Intestinal Diseases - etiology | Prostate cancer | Cancer patients | Electric utilities
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13. Full Text Retrospective Evaluation of Treatment Outcome in Japanese Children with Complete Unilateral Cleft Lip and Palate. Part 1: Five-Year-Olds’ Index for Dental Arch Relationships
by Suzuki, Akira and Yoshizaki, Keigo and Honda, Yasuo and Sasaguri, Masaaki and Kubota, Yasutaka and Nakamura, Norifumi and Ohishi, Masamichi and Oka, Masuichiro and Tashiro, Hideo and Katsuki, Takeshi and Fujino, Hiroshi
The Cleft Palate-Craniofacial Journal, ISSN 1055-6656, 7/2007, Volume 44, Issue 4, pp. 434 - 443
Objective: To evaluate the dental arch relationships of Japanese children with complete unilateral cleft lip and palate (UCLP) and to examine the 5-year-olds’... 
Occlusal outcome | 5-year-olds' index | Cephalometrics | Model analysis | Cleft lip and palate | Dental arch relationship | Cephalometry - methods | Humans | Mandible - pathology | Cleft Palate - surgery | Child, Preschool | Male | Treatment Outcome | Dental Models | Radiography | Asian Continental Ancestry Group | Dental Arch - pathology | Epidemiologic Methods | Malocclusion - pathology | Sex Factors | Head - diagnostic imaging | Female | Maxilla - pathology | Cleft Lip - surgery | Birth defects | Deformities | Mouth | Children & youth
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14. Full Text Production of nonequilibrium plasma and MHD interaction in disk MHD channel
by Oda, Noritaka and Suzuki, Masafumi and Fujino, Takayasu and Okuno, Yoshihiro and Yamasaki, Hiroyuki
Electrical Engineering in Japan, ISSN 0424-7760, 03/2002, Volume 138, Issue 4, pp. 42 - 49
The production of nonequilibrium plasma and the fluid flow with the MHD interaction are examined experimentally with a shock‐tube driven disk channel with no... 
total pressure loss | disk MHD channel | nonequilibrium plasma | MHD interaction | magnetohydrodynamics | Nonequilibrium plasma | Magnetohydrodynamics | Total pressure loss | Disk MHD channel | ENGINEERING, ELECTRICAL & ELECTRONIC
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15. ELEVATOR CONTROL DEVICE AND ELEVATOR CONTROL METHOD
by TAKAHASHI HIROTOMO and KATSUKI HIRONAO and SAITO TATSURO and FUJINO ATSUYA and MATSUDO TAKASHI and FUKUDA TOSHIO and AIDA KEIICHI and KURAKANE TAKEFUMI
08/2006
PROBLEM TO BE SOLVED: To provide an elevator control device and an elevator control method, having no risk of declining service due to a feeling of distrust... 
ELEVATORS | TRANSPORTING | HOISTING | ESCALATORS OR MOVING WALKWAYS | LIFTING | PERFORMING OPERATIONS | HAULING
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16. RAIL WIRE TIE, AND JOINING METHOD FOR RAIL
by KATSUKI MAKOTO and ISHIKAWA NOBUYOSHI and FUJINO NORIYUKI and HAKIRI KATSUSHI and NAKANOWATARI HIROMASA and KAWAMURA HIDEYUKI and KISHIDA HITOSHI
01/2005, 7
PROBLEM TO BE SOLVED: To provide a rail wire tie which is easy in transportation, assembly and removal, securely clamps a rail and stably applies prescribed... 
TRANSPORTING | MACHINE TOOLS | WORKING BY LASER BEAM | CLADDING OR PLATING BY SOLDERING OR WELDING | METAL-WORKING NOT OTHERWISE PROVIDED FOR | WELDING | SOLDERING OR UNSOLDERING | CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING | PERFORMING OPERATIONS
Patent
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17. CAMERA MONITOR, PRINTED-BOARD INSPECTING DEVICE USING CAMERA MONITOR AND INSPECTING DEVICE USING CAMERA MONITOR
by FUJINO KAZUYUKI and SAGAWA KATSUKI and NAKAZAWA ISAMU and KAMEDA ISAMU
06/1997, 6
PROBLEM TO BE SOLVED: To provide a camera monitor, which can operate lighting so that a part to be observed is excellently observed, a printed-board inspecting... 
MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS | TESTING STATIC OR DYNAMIC BALANCE OF MACHINES ORSTRUCTURES | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES | MEASURING | TESTING STRUCTURES OR APPARATUS NOT OTHERWISE PROVIDED FOR | TESTING | ELECTRIC COMMUNICATION TECHNIQUE | CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS | PHYSICS | ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR | PICTORIAL COMMUNICATION, e.g. TELEVISION | ELECTRICITY | PRINTED CIRCUITS
Patent
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18. EQUIPMENT FOR CENTRIFUGAL SEPARATION PROCESSING
by TABUCHI HIROYOSHI and TAKAHASHI KATSUKI and FUJINO KENJI and KODATE MASATO
09/1996, 6
PURPOSE: To execute a centrifugal separation processing quickly and efficiently. CONSTITUTION: Eight holding parts 44 of a centrifugal separation means 40 are... 
TRANSPORTING | TESTING | CENTRIFUGES | CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL ORCHEMICAL PROCESSES | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES | MEASURING | PHYSICS | PERFORMING OPERATIONS
Patent
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19. HOLDING DEVICE FOR BODY TO BE WORKED
by SHINGU KATSUKI and UEDA SHUJI and FUJINO KAZUHIKO
07/1990
PURPOSE:To eliminate the positional error of the center of curvature of a polishing bowl and the body to be worked and to finish in a highly accurate spherical... 
TRANSPORTING | MACHINE TOOLS | METAL-WORKING NOT OTHERWISE PROVIDED FOR | DETAILS, COMPONENTS, OR ACCESSORIES FOR MACHINE TOOLS, e.g.ARRANGEMENTS FOR COPYING OR CONTROLLING | COMBINATIONS OR ASSOCIATIONS OF METAL-WORKING MACHINES, NOTDIRECTED TO A PARTICULAR RESULT | MACHINE TOOLS IN GENERAL CHARACTERISED BY THE CONSTRUCTION OFPARTICULAR DETAILS OR COMPONENTS | PERFORMING OPERATIONS
Patent
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20. JP2638926B
by MATSUMURA KENICHI and SHINGU KATSUKI and INOE MAMORU and UEDA SHUJI and FUJINO KAZUHIKO and MAYAHARA KYOSHI
08/1997, 6
TRANSPORTING | GRINDING | FEEDING OF GRINDING, POLISHING, OR LAPPING AGENTS | PERFORMING OPERATIONS | POLISHING | MACHINES, DEVICES, OR PROCESSES FOR GRINDING OR POLISHING | DRESSING OR CONDITIONING OF ABRADING SURFACES
Patent
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