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Cancer Science, ISSN 1347-9032, 12/2016, Volume 107, Issue 12, pp. 1818 - 1824
GBS‐01, an extract from the fruit of Arctium lappa L. is an orally administered drug rich in arctigenin, which has been reported to exert antitumor activity by... 
Arctigenin | phase I trial | pancreatic cancer | gemcitabine | chemotherapy | natural anticancer compound | CELLS | FOLFIRINOX | TOLERANCE | IDENTIFICATION | TUMORS | THERAPY | ONCOLOGY | S-1 | STARVATION | Humans | Middle Aged | Deoxycytidine - pharmacology | Drug Resistance, Neoplasm | Male | Tomography, X-Ray Computed | Biomarkers, Tumor | Pancreatic Neoplasms - drug therapy | Antineoplastic Agents, Phytogenic - administration & dosage | Deoxycytidine - therapeutic use | Neoplasm Metastasis | Adult | Female | Pancreatic Neoplasms - mortality | Antineoplastic Agents, Phytogenic - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacokinetics | Antineoplastic Agents, Phytogenic - adverse effects | Pancreatic Neoplasms - pathology | Neoplasm Recurrence, Local | Treatment Outcome | Maximum Tolerated Dose | Survival Analysis | Aged | Drug Monitoring | Neoplasm Staging | Deoxycytidine - analogs & derivatives | Antimitotic agents | Chemotherapy | Hyperglycemia | Pancreatic cancer | Clinical trials | Product development | Bilirubin | Antineoplastic agents | Cancer | Gemcitabine | g-Glutamyltransferase | Toxicity | Oral administration | Metastasis | Bioavailability | Glucose | Cancer therapies | Patients | Fruits | Herbal medicine | Tomography | Antitumor activity | Hypoxia | Pharmacokinetics | Pharmaceutical industry | Drug dosages | Tumors | Index Medicus | Original
Journal Article
Cancer Science, ISSN 1347-9032, 12/2019, Volume 110, Issue 12, pp. 3802 - 3810
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0198219
Arctigenin is evaluated for antitumor efficacy in patients with pancreatic cancer. It has an inhibitory activity on mitochondrial complex I .Therefore, plasma... 
SPRAGUE-DAWLEY RATS | NUTRIENT DEPRIVATION | CELLS | THERAPY | METABOLISM | PATHWAY | TOLERANCE | GLUCOSE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | STARVATION | Area Under Curve | Lactic Acid - blood | Gluconeogenesis - drug effects | Humans | Carcinoma, Adenosquamous - drug therapy | Deoxycytidine - pharmacology | Drug Resistance, Neoplasm | Liver - physiopathology | Furans - therapeutic use | Lignans - therapeutic use | Oxidative Phosphorylation - drug effects | Pancreatic Neoplasms - drug therapy | Furans - pharmacokinetics | Arctium - chemistry | Antineoplastic Agents, Phytogenic - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacokinetics | Drugs, Chinese Herbal - therapeutic use | Kidney - physiopathology | Pancreatic Neoplasms - blood | Kaplan-Meier Estimate | Biomarkers - blood | Mitochondria - drug effects | Carcinoma, Adenosquamous - blood | Carcinoma, Pancreatic Ductal - blood | Carcinoma, Pancreatic Ductal - drug therapy | Drugs, Chinese Herbal - pharmacokinetics | Lignans - pharmacokinetics | Cell Line, Tumor | Plant Extracts - therapeutic use | Deoxycytidine - analogs & derivatives | Drug Screening Assays, Antitumor | Lactates | Development and progression | Care and treatment | Genetic aspects | Identification and classification | Pancreatic cancer | Plasma | Diabetic retinopathy | Gemcitabine | Liver | Clinical trials | Oncology | Colorimetry | Kinases | Cancer therapies | Anticancer properties | Electron transport chain | Mitochondria | Rodents | Surgery | Pharmaceutical industry | NADH-ubiquinone oxidoreductase | Statistical analysis | Pharmacology | Metabolism | Patients | Chemotherapy | Biomarkers | Antitumor activity | Hypoxia | Lactic acid | Respiration | Alzheimers disease | Pharmacokinetics | Cancer
Journal Article
Carbohydrate Polymers, ISSN 0144-8617, 2006, Volume 64, Issue 2, pp. 345 - 349
Synthesis of novel hydrogels has been investigated with the reaction of starch and succinic anhydride (SA), using 4-dimethylaminopyridine as esterification... 
Biodegradation | Hydrogel | Swelling | Starch | POLYMER SCIENCE | hydrogel | CROSS-LINKING | CHEMISTRY, ORGANIC | biodegradation | starch | swelling | CHEMISTRY, APPLIED | DERIVATIVES | CASSAVA STARCH | SUPERABSORBENT | Chemical properties | Chemical tests and reagents | Organic solvents | Rain and rainfall
Journal Article
Journal Article
Cancer science, ISSN 1347-9032, 04/2020
HER2-targeting antibodies (trastuzumab, pertuzumab) and a HER2-directed antibody-drug conjugate (trastuzumab emtansine: T-DM1) are used for the treatment of... 
Journal Article
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 03/2005, Volume 69
Journal Article
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 03/2005, Volume 69
Journal Article
MOLECULAR CANCER RESEARCH, ISSN 1541-7786, 11/2019, Volume 17, Issue 11, pp. 2233 - 2243
Despite the worldwide approval of three generations of EGFR tyrosine kinase inhibitors (TKI) for advanced non-small cell lung cancers with EGFR mutations, no... 
CELL LUNG-CANCER | MUTANTS | OSIMERTINIB | ONCOLOGY | ADENOCARCINOMAS | CELL BIOLOGY | lung cancer | EGFR exon 20 insertion mutations | adenocarcinoma | tyrosine kinase inhibitor | TAS6417, CLN-081
Journal Article
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 03/2004, Volume 68
Journal Article
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 03/2004, Volume 68
Journal Article
The American Journal of Physiology, ISSN 0002-9513, 05/2009, Volume 296, Issue 5, p. E1013
The present study was performed to investigate the involvement of SNARK in physical activity levels in mice. To examine the acute effect of SNARK deficiency on... 
Prevention | Adipose tissues | Obesity | Exercise | Physiological aspects | Research | Risk factors
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2013, Volume 31, Issue 15_suppl, pp. 2559 - 2559
2559 Background: Arctigenin, which is abundant in the seeds of Arctium lappa Linné, was found by a novel strategy to attenuate cancer cells’ tolerance to... 
Journal Article
American Journal of Physiology, ISSN 0193-1849, 05/2009, Volume 296, Issue 5, p. E1013
  The present study was performed to investigate the involvement of SNARK in physical activity levels in mice. To examine the acute effect of SNARK deficiency... 
Studies | Genotype & phenotype | Obesity | Exercise | Rodents | Metabolism
Journal Article
Journal of PHYSIOLOGICAL ANTHROPOLOGY, ISSN 1880-6791, 2010, Volume 29, Issue 2, pp. 51 - 58
「Abstract」To elucidate how aging affects the muscular load required for pulling up pants-style disposable diapers, and why some elderly people cannot pull up... 
Journal Article
05/2006
الملخص: يتعلق الاختراع بأداة ماصة تستخدم لمرة واحدة disposable absorbent article تكون من لب ماض للسوائل يتم توفيره بشكل متقطع في الاتجاه الطولي والاتجاه... 
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES | TREATMENT OR PROTECTION OF EYES OR EARS | BANDAGES, DRESSINGS OR ABSORBENT PADS | HYGIENE | FILTERS IMPLANTABLE INTO BLOOD VESSELS | MEDICAL OR VETERINARY SCIENCE | PROSTHESES | DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS | HUMAN NECESSITIES | FIRST-AID KITS | FOMENTATION
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