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Nature communications, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1490 - 14
Spatial/temporal control of Cas9 guide RNA expression could considerably expand the utility of CRISPR-based technologies. Current approaches based on tRNA... 
CRISPR | Design engineering | Decoupling | tRNA | Genomes | Gene expression | Ribonucleic acid--RNA | Scaffolds
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8790 - 10
Mutations of the gene MEGF8 cause Carpenter syndrome in humans, and the mouse orthologue has been functionally associated with Nodal and Bmp4 signalling. Here,... 
PROTEIN | BEHAVIOR | RAB23 | MULTIDISCIPLINARY SCIENCES | GROWTH | PLANAR CELL POLARITY | MECHANISMS | MUTATIONS | EXPRESSION | POLARIZATION | MELANOGASTER | CRISPR | Bone morphogenetic protein 4 | Phenotypes | Feeding behavior | Sucrose | Insects | RNA-mediated interference | Lethality | Instars | Mutation
Journal Article
Wiley Interdisciplinary Reviews, ISSN 1759-7684, 05/2016, Volume 5, Issue 3, p. i
  The cover image, by Tudor Fulga et al., is based on the Advanced Review Tiny giants of gene regulation: experimental strategies for microRNA functional... 
Layouts | Gene regulation | MiRNA
Journal Article
Genetics, ISSN 0016-6731, 06/2015, Volume 200, Issue 2, pp. 569 - 569
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression post-transcriptionally. Prior studies have shown that they regulate numerous... 
Journal Article
PLoS Genetics, ISSN 1553-7390, 05/2015, Volume 11, Issue 5
  RNA interference-related silencing mechanisms concern very diverse and distinct biological processes, from gene regulation (via the microRNA pathway) to... 
Proteins | Insects | Genomics | MicroRNAs | Biosynthesis | Genomes | Parasites | Gene expression | Experiments
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2016, Volume 113, Issue 32, p. E4688
  In Parkinson's disease, misfolded a-synuclein accumulates, often in a ubiquitinated form, in neuronal inclusions termed Lewy bodies. An important outstanding... 
Insects | Pathogenesis | Toxicity | Parkinsons disease | Comparative analysis
Journal Article
Nature, ISSN 0028-0836, 07/2007, Volume 448, Issue 7151, pp. 362 - 365
Although directed migration is a feature of both individual cells and cell groups, guided migration has been studied most extensively for single cells in... 
MORPHOGENESIS | PROTEIN | PATHWAY | MULTIDISCIPLINARY SCIENCES | DROSOPHILA OOGENESIS | MICROSCOPY | ZEBRAFISH LATERAL-LINE | EGF RECEPTOR | Protein Kinases - metabolism | Protein Kinases - genetics | Adaptor Proteins, Vesicular Transport - genetics | ErbB Receptors - genetics | rac GTP-Binding Proteins - metabolism | Drosophila Proteins - metabolism | raf Kinases - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Receptors, Invertebrate Peptide - genetics | Receptors, Vascular Endothelial Growth Factor - metabolism | raf Kinases - genetics | Genes, Essential - genetics | Shc Signaling Adaptor Proteins | Phospholipase C gamma - metabolism | ErbB Receptors - metabolism | Signal Transduction | Drosophila melanogaster - cytology | Mutation - genetics | Animals | Receptors, Platelet-Derived Growth Factor - metabolism | Adaptor Proteins, Signal Transducing - genetics | Receptors, Invertebrate Peptide - metabolism | Drosophila Proteins - genetics | Adaptor Proteins, Signal Transducing - metabolism | Cell Movement | Mitogen-Activated Protein Kinases - metabolism | Genetic aspects | Motility | Research | Drosophila | Cell migration | Cells | Proteins | Signal transduction | Cellular biology | Insects | Fish | Genetics | Cell adhesion & migration | Receptors | Pathways | Migration | Clusters | Kinases | Signalling | Borders | Life Sciences
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1580, pp. 79 - 97
Post-transcriptional silencing by microRNAs (miRNAs) is a critical constituent of eukaryotic gene regulation. miRNAs are short (~22nt) noncoding RNAs capable... 
microRNAs | miRNA response elements (MRE) | miRNA | Genome engineering | CRISPR/Cas9 | Cell Line | RNA, Guide - genetics | Response Elements | Humans | Cell Culture Techniques - methods | Animals | Transfection - methods | CRISPR-Cas Systems | Clustered Regularly Interspaced Short Palindromic Repeats | Gene Editing - methods | MicroRNAs - genetics | Mutation | Genome
Journal Article
Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, p. 14633
Journal Article
Nature Methods, ISSN 1548-7091, 2009, Volume 6, Issue 12, pp. 897 - 903
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e38174
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 11/2014, Volume 21, Issue 11, pp. 955 - 961
Journal Article
Journal Article
Genetics, ISSN 0016-6731, 03/2018, Volume 208, Issue 3, pp. 1195 - 1207
We describe a genome-wide microRNA (miRNA)-based screen to identify brain glial cell functions required for circadian behavior. To identify glial miRNAs that... 
Glial biology | microRNA | Astrocyte | Circadian behavior | glial biology | CELLS | LOCOMOTOR-ACTIVITY | ASTROCYTES | ENTRAINMENT | RHYTHMS | SUPRACHIASMATIC NUCLEUS | GENETICS & HEREDITY | circadian behavior | GLIA | CLUSTER | astrocyte | EXPRESSION | MELANOGASTER | Immunohistochemistry | Locomotion | Organ Specificity - genetics | Animals | Astrocytes | Circadian Rhythm - genetics | Neuroglia - metabolism |