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1. The role of miR-21 and miR-211 on MMP9 regulation in pancreatic ductal adenocarcinoma: Cooperation in invasiveness behaviors?
by Funel, Niccola
Epigenomics, ISSN 1750-1911, 06/2015, Volume 7, Issue 3, pp. 333 - 335
miRNA | PDAC | miR-21 | invasion | MMP9 | miR-211 | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Pancreatic Neoplasms - metabolism | Neoplasm Invasiveness | Humans | Pancreatic Neoplasms - pathology | Carcinoma, Pancreatic Ductal - metabolism | Gene Expression Regulation, Neoplastic | Pancreatic Neoplasms - enzymology | MicroRNAs - metabolism | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Carcinoma, Pancreatic Ductal - genetics | Carcinoma, Pancreatic Ductal - enzymology | Gene Expression Regulation, Enzymologic | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics
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2. Full Text A propensity score-matched analysis of robotic versus open pancreatoduodenectomy for pancreatic cancer based on margin status
by Kauffmann, Emanuele F and Kauffmann, Emanuele F and Napoli, Niccolò and Napoli, Niccolò and Menonna, Francesca and Menonna, Francesca and Iacopi, Sara and Iacopi, Sara and Lombardo, Carlo and Lombardo, Carlo and Bernardini, Juri and Bernardini, Juri and Amorese, Gabriella and Amorese, Gabriella and Cacciato Insilla, Andrea and Cacciato Insilla, Andrea and Funel, Niccola and Funel, Niccola and Campani, Daniela and Campani, Daniela and Cappelli, Carla and Cappelli, Carla and Caramella, Davide and Caramella, Davide and Boggi, Ugo and Boggi, Ugo
Surgical endoscopy, ISSN 0930-2794, 1/2019, Volume 33, Issue 1, pp. 234 - 242
Sample size calculation | Gynecology | Propensity score | Medicine & Public Health | Robotic pancreatoduodenectomy | Surgery | Hepatology | Pancreatic cancer | Gastroenterology | Abdominal Surgery | Tumor margins | Proctology | Pancreatoduodenectomy | Life Sciences & Biomedicine | Science & Technology | Robotic Surgical Procedures - methods | Survival Rate - trends | Follow-Up Studies | Humans | Middle Aged | Pancreatic Neoplasms - surgery | Margins of Excision | Male | Postoperative Complications - epidemiology | Case-Control Studies | Incidence | Pancreaticoduodenectomy - methods | Propensity Score | Female | Italy - epidemiology | Aged | Pancreatic Neoplasms - mortality | Retrospective Studies | Index Medicus
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3. Full Text PTEN Expression and KRAS Mutations on Primary Tumors and Metastases in the Prediction of Benefit From Cetuximab Plus Irinotecan for Patients With Metastatic Colorectal Cancer
by Fotios Loupakis and Luca Pollina and Irene Stasi and Annamaria Ruzzo and Mario Scartozzi and Daniele Santini and Gianluca Masi and Francesco Graziano and Chiara Cremolini and Eliana Rulli and Emanuele Canestrari and Niccola Funel and Gaia Schiavon and Iacopo Petrini and Mauro Magnani and Giuseppe Tonini and Daniela Campani and Irene Floriani and Stefano Cascinu and Alfredo Falcone
Journal of clinical oncology, ISSN 0732-183X, 06/2009, Volume 27, Issue 16, pp. 2622 - 2629
Life Sciences & Biomedicine | Oncology | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Medical sciences | Tumors | Immunohistochemistry | Predictive Value of Tests | ras Proteins - genetics | Phosphorylation | Proto-Oncogene Proteins p21(ras) | Colorectal Neoplasms - genetics | Humans | Middle Aged | PTEN Phosphohydrolase - analysis | Drug Resistance, Neoplasm | Male | Patient Selection | Antibodies, Monoclonal, Humanized | Antineoplastic Agents, Phytogenic - administration & dosage | Time Factors | DNA Mutational Analysis | Colorectal Neoplasms - drug therapy | Adult | Camptothecin - administration & dosage | Female | Retrospective Studies | Cetuximab | Camptothecin - analogs & derivatives | Colorectal Neoplasms - mortality | Colorectal Neoplasms - enzymology | Risk Assessment | Kaplan-Meier Estimate | Proportional Hazards Models | Proto-Oncogene Proteins - genetics | Treatment Outcome | Receptor, Epidermal Growth Factor - analysis | Protein Kinase Inhibitors - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins c-akt - analysis | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Colorectal Neoplasms - secondary | Italy - epidemiology | Aged | Mutation | Longitudinal Studies | Index Medicus
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4. Full Text TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
by Ottaviani, Silvia and Stebbing, Justin and Frampton, Adam E and Zagorac, Sladjana and Krell, Jonathan and de Giorgio, Alexander and Trabulo, Sara M and Nguyen, Van T. M and Magnani, Luca and Feng, Hugang and Giovannetti, Elisa and Funel, Niccola and Gress, Thomas M and Jiao, Long R and Lombardo, Ylenia and Lemoine, Nicholas R and Heeschen, Christopher and Castellano, Leano
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 1845 - 18
a_open_article_in_open_journal | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | RNA-Binding Proteins - genetics | Up-Regulation | MicroRNAs - antagonists & inhibitors | Humans | Transforming Growth Factor beta1 - metabolism | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Carcinoma, Pancreatic Ductal - genetics | Female | Datasets as Topic | Introns - genetics | Pancreatic Neoplasms - pathology | Carcinogenesis - genetics | Pancreas - pathology | Pancreatic Neoplasms - genetics | Signal Transduction - genetics | Carcinoma, Pancreatic Ductal - pathology | Disease Progression | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cell Line, Tumor | Mice | MicroRNAs - genetics | RNA-Binding Proteins - metabolism | RNA, Small Interfering - metabolism | Adenocarcinoma | Deactivation | Mesenchyme | Transcription | p53 Protein | Cell junctions | Inactivation | Argonaute 2 protein | Ribonucleic acid--RNA | Coding | Smad2 protein | miRNA | Activin | Pancreas | Index Medicus
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5. Full Text Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer
by Childs, Erica J and Mocci, Evelina and Campa, Daniele and Bracci, Paige M and Gallinger, Steven and Goggins, Michael and Li, Donghui and Neale, Rachel E and Olson, Sara H and Scelo, Ghislaine and Amundadottir, Laufey T and Bamlet, William R and Bijlsma, Maarten F and Blackford, Amanda and Borges, Michael and Brennan, Paul and Brenner, Hermann and Bueno-de-Mesquita, H. Bas and Canzian, Federico and Capurso, Gabriele and Cavestro, Giulia M and Chaffee, Kari G and Chanock, Stephen J and Cleary, Sean P and Cotterchio, Michelle and Foretova, Lenka and Fuchs, Charles and Funel, Niccola and Gazouli, Maria and Hassan, Manal and Herman, Joseph M and Holcatova, Ivana and Holly, Elizabeth A and Hoover, Robert N and Hung, Rayjean J and Janout, Vladimir and Key, Timothy J and Kupcinskas, Juozas and Kurtz, Robert C and Landi, Stefano and Lu, Lingeng and Malecka-Panas, Ewa and Mambrini, Anea and Mohelnikova-Duchonova, Beatrice and Neoptolemos, John P and Oberg, Ann L and Orlow, Irene and Pasquali, Claudio and Pezzilli, Raffaele and Rizzato, Cosmeri and Saldia, Amethyst and Scarpa, Aldo and Stolzenberg-Solomon, Rachael Z and Strobel, Oliver and Tavano, Francesca and Vashist, Yogesh K and Vodicka, Pavel and Wolpin, Brian M and Yu, Herbert and Petersen, Gloria M and Risch, Harvey A and Klein, Alison P
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 8, pp. 911 - 916
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease - genetics | Europe | Gene Frequency | Humans | Middle Aged | Risk Factors | Genetic Loci - genetics | Genotype | Male | Pancreatic Neoplasms - genetics | North America | Chromosomes, Human, Pair 17 - genetics | Chromosomes, Human, Pair 2 - genetics | Female | Aged | Polymorphism, Single Nucleotide | Australia | Chromosomes, Human, Pair 7 - genetics | Genome-Wide Association Study - methods | Chromosomes, Human, Pair 3 - genetics | Genetic susceptibility | Genetic variation | Pancreatic cancer | Oncology, Experimental | Genetic research | Genetic aspects | Research | Identification and classification | Health aspects | Risk factors | Cancer | Genetics | Mutation | Genes | Index Medicus
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6. Full Text FOLFIRINOX and translational studies: Towards personalized therapy in pancreatic cancer
by Chiara Caparello Laura L Meijer Ingrid Garajova Alfredo Falcone Tessa Y Le Large Niccola Funel Geert Kazemier Godefridus J Peters Enrico Vasile Elisa Giovannetti
World journal of gastroenterology : WJG, ISSN 1007-9327, 2016, Volume 22, Issue 31, pp. 6987 - 7005
treatments;MicroR | cancer | therapy;New | NA;Pancreatic | FOLFIRINOX;Personalized | FOLFIRINOX | MicroRNA | Personalized therapy | Pancreatic cancer | New treatments | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Leucovorin - administration & dosage | ErbB Receptors - antagonists & inhibitors | Humans | Translational Medical Research | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Pancreatic Neoplasms - drug therapy | Irinotecan | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Oxaliplatin | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Camptothecin - administration & dosage | Pancreatic Neoplasms - mortality | Camptothecin - analogs & derivatives | Precision Medicine | Index Medicus | Review
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7. Full Text Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine
by Giovannetti, Elisa and Del Tacca, Mario and Mey, Valentina and Funel, Niccola and Nannizzi, Sara and Ricci, Sergio and Orlandini, Cinzia and Boggi, Ugo and Campani, Daniela and Del Chiaro, Marco and Iannopollo, Mauro and Bevilacqua, Generoso and Mosca, Franco and Danesi, Romano
Cancer research (Chicago, Ill.), ISSN 0008-5472, 04/2006, Volume 66, Issue 7, pp. 3928 - 3935
Oncology | Cancer Research | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Antineoplastic agents | Tumors | 5'-Nucleotidase - genetics | Predictive Value of Tests | Pancreatic Neoplasms - metabolism | Prognosis | Humans | Middle Aged | Transcriptional Activation | Male | Pancreatic Neoplasms - drug therapy | Cytidine Deaminase - biosynthesis | Deoxycytidine - therapeutic use | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Adult | Female | Deoxycytidine Kinase - genetics | 5'-Nucleotidase - biosynthesis | Gene Expression | Cytidine Deaminase - genetics | Equilibrative Nucleoside Transporter 1 - biosynthesis | Equilibrative Nucleoside Transporter 1 - genetics | Pancreatic Neoplasms - genetics | Ribonucleoside Diphosphate Reductase - genetics | Treatment Outcome | Reverse Transcriptase Polymerase Chain Reaction | Deoxycytidine Kinase - biosynthesis | Cell Line, Tumor | Aged | Ribonucleoside Diphosphate Reductase - biosynthesis | Tumor Suppressor Proteins - biosynthesis | Deoxycytidine - analogs & derivatives | Index Medicus
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8. Synergistic activity of the c-Met and tubulin inhibitor tivantinib (ARQ197) with pemetrexed in mesothelioma cells
by Leon, Leticia G and Gemelli, Maria and Sciarrillo, Rocco and Avan, Amir and Fune, Niccola and Giovannetti, Elisa
Current drug targets, ISSN 1389-4501, 01/2014, Volume 15, Issue 14, pp. 1331 - 1340
Tubulin | Synergistic interaction | Migration | c-Met | Malignant pleural mesothelioma | Pemetrexed | Tivantinib | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Proto-Oncogene Proteins c-met - metabolism | Guanine - analogs & derivatives | Humans | Lung Neoplasms - metabolism | Quinolines - pharmacology | Pleural Neoplasms - metabolism | Microtubules - metabolism | Guanine - pharmacology | Pyrrolidinones - pharmacology | Antineoplastic Agents - pharmacology | Drug Evaluation, Preclinical | Pleural Neoplasms - pathology | Lung Neoplasms - genetics | Mesothelioma - genetics | Thymidylate Synthase - genetics | Proto-Oncogene Proteins c-met - genetics | Drug Synergism | Cell Movement - drug effects | Mesothelioma - metabolism | Glutamates - pharmacology | Cell Line, Tumor | Cell Proliferation - drug effects | Mesothelioma, Malignant | Apoptosis
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9. Full Text Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
by Wolpin, Brian M and Rizzato, Cosmeri and Kraft, Peter and Kooperberg, Charles and Petersen, Gloria M and Wang, Zhaoming and Arslan, Alan A and Beane-Freeman, Laura and Bracci, Paige M and Buring, Julie and Canzian, Federico and Duell, Eric J and Gallinger, Steven and Giles, Graham G and Goodman, Gary E and Goodman, Phyllis J and Jacobs, Eric J and Kamineni, Aruna and Klein, Alison P and Kolonel, Laurence N and Kulke, Matthew H and Li, Donghui and Malats, Núria and Olson, Sara H and Risch, Harvey A and Sesso, Howard D and Visvanathan, Kala and White, Emily and Zheng, Wei and Abnet, Christian C and Albanes, Demetrius and Andreotti, Gabriella and Austin, Melissa A and Barfield, Richard and Basso, Daniela and Berndt, Sonja I and Boutron-Ruault, Marie-Christine and Brotzman, Michelle and Büchler, Markus W and Bueno-De-Mesquita, H Bas and Bugert, Peter and Burdette, Laurie and Campa, Daniele and Caporaso, Neil E and Capurso, Gabriele and Chung, Charles and Cotterchio, Michelle and Costello, Eithne and Elena, Joanne and Funel, Niccola and Gaziano, J Michael and Giese, Nathalia A and Giovannucci, Edward L and Goggins, Michael and Gorman, Megan J and Gross, Myron and Haiman, Christopher A and Hassan, Manal and Helzlsouer, Kathy J and Henderson, Brian E and Holly, Elizabeth A and Hu, Nan and Hunter, David J and Innocenti, Federico and Jenab, Mazda and Kaaks, Rudolf and Key, Timothy J and Khaw, Kay-Tee and Klein, Eric A and Kogevinas, Manolis and Krogh, Vittorio and Kupcinskas, Juozas and Kurtz, Robert C and Lacroix, Andrea and Landi, Maria T and Landi, Stefano and Le Marchand, Loic and Mambrini, Andrea and Mannisto, Satu and Milne, Roger L and Nakamura, Yusuke and Oberg, Ann L and Owzar, Kouros and Patel, Alpa V and Peeters, Petra H.M and Peters, Ulrike and Pezzilli, Raffaele and Piepoli, Ada and Porta, Miquel and Real, Francisco X and Riboli, Elio and Rothman, Nathaniel and Scarpa, Aldo and Shu, Xiao-Ou and Silverman, Debra T and Soucek, Pavel and Sund, Malin and Talar-Wojnarowska, Renata and Taylor, Philip R and Theodoropoulos, George E and ...
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 9, pp. 994 - 1000
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Humans | Middle Aged | Genotype | Male | Pancreatic Neoplasms - genetics | Genetic Loci | Case-Control Studies | Polymorphism, Single Nucleotide - genetics | Female | Aged | Genome-Wide Association Study - methods | Studies | Proteins | Medical research | Pancreatic cancer | Cell cycle | Genomes | Mutation | Pancreas | Epidemiology | Cell adhesion & migration | Index Medicus
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