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2007, Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance
Web Resource
2007, Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance
Web Resource
Chemico-Biological Interactions, ISSN 0009-2797, 11/2016, Volume 259, Issue Pt B, pp. 51 - 62
Paraoxonase-1 (PON1), an esterase/lactonase primarily associated with plasma high-density lipoprotein (HDL), was the first member of this family of enzymes to... 
Oxidative stress | Paraoxonases | Human disease | Organophosphate | Anti-inflammatory | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOW-DENSITY-LIPOPROTEIN | CHLORPYRIFOS-OXON | IN-VIVO | PHARMACOLOGY & PHARMACY | HUMAN-SERUM PARAOXONASE | ENDOPLASMIC-RETICULUM | TOXICOLOGY | SIGNAL N-(3-OXODODECANOYL)-L-HOMOSERINE LACTONE | ISCHEMIC-STROKE | CORONARY-ARTERY-DISEASE | PARKINSONS-DISEASE | Mitochondria - enzymology | Oxidative Stress | Ticlopidine - therapeutic use | Lipoproteins, HDL - blood | Humans | Male | Neurons - cytology | Homocysteine - metabolism | Homocysteine - analogs & derivatives | Organophosphorus Compounds - metabolism | Female | Neurons - metabolism | Aryldialkylphosphatase - deficiency | Platelet Aggregation Inhibitors - therapeutic use | Carotid Artery Diseases - metabolism | Carotid Artery Diseases - drug therapy | Astrocytes - cytology | Endoplasmic Reticulum - enzymology | Carotid Artery Diseases - etiology | Quorum Sensing | Cells, Cultured | Genotype | Inflammation | Aryldialkylphosphatase - genetics | Aryldialkylphosphatase - metabolism | Ticlopidine - analogs & derivatives | Mice, Knockout | Animals | Mice | Lipid Metabolism - physiology | Astrocytes - metabolism | Animal experimentation | Enzymes | Neurosciences | Gallstones | Insecticides | Development and progression | Antioxidants | Prevention | Metabolites | Analysis | Atherosclerosis | Medical genetics | Physiological aspects | Cancer
Journal Article
Journal Article
Toxicology, ISSN 0300-483X, 5/2013, Volume 307, pp. 46 - 54
Exposure to organophosphorus (OP) compounds can lead to serious neurological damage or death. Following bioactivation by the liver cytochromes P450, the OP... 
Biomarkers | Protein adducts | Mass spectrometry | Organophosphates
Journal Article
Analytical Chemistry, ISSN 0003-2700, 09/2008, Volume 80, Issue 17, pp. 6747 - 6751
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2009, Volume 235, Issue 1, pp. 1 - 9
Paraoxonase 1 (PON1) hydrolyzes a number of organophosphorus (OP) compounds including insecticides and nerve agents. The efficacy of PON1 to protect against a... 
PON1 polymorphism | Chlorpyrifos | Pharmacogenetics | Paraoxonase 1 | Diazoxon | Chlorpyrifos oxon | Diazinon | CHLORPYRIFOS OXON | TOXICITY | Chlorpyrifos axon | ARYLESTERASE | GENE | Q192R POLYMORPHISM | PHARMACOLOGY & PHARMACY | HUMAN-SERUM PARAOXONASE | TOXICOLOGY | CORONARY-HEART-DISEASE | PROMOTER | MOLECULAR-BASIS | EXPRESSION | Chlorpyrifos - analogs & derivatives |