Lancet Oncology, The, ISSN 1470-2045, 2011, Volume 12, Issue 8, pp. 815 - 824
Summary Adenoid cystic carcinomas (ACC) are rare cancers usually arising in the salivary glands. Once metastatic, the natural history can vary; some patients...
Hematology, Oncology and Palliative Medicine | PHASE-II TRIAL | ONCOLOGY-GROUP | MALIGNANT-TUMORS | PROGNOSTIC-FACTORS | ONCOLOGY | C-KIT | FOLLOW-UP | COOPERATIVE GROUP | CISPLATIN COMBINATION CHEMOTHERAPY | DISTANT METASTASES | IMATINIB MESYLATE | Recurrence | Carcinoma, Adenoid Cystic - drug therapy | Salivary Gland Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans | Carcinoma, Adenoid Cystic - secondary | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Chemotherapy | Relapse | Analysis | Lung cancer | Metastasis | Cancer | Diseases
Hematology, Oncology and Palliative Medicine | PHASE-II TRIAL | ONCOLOGY-GROUP | MALIGNANT-TUMORS | PROGNOSTIC-FACTORS | ONCOLOGY | C-KIT | FOLLOW-UP | COOPERATIVE GROUP | CISPLATIN COMBINATION CHEMOTHERAPY | DISTANT METASTASES | IMATINIB MESYLATE | Recurrence | Carcinoma, Adenoid Cystic - drug therapy | Salivary Gland Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans | Carcinoma, Adenoid Cystic - secondary | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Chemotherapy | Relapse | Analysis | Lung cancer | Metastasis | Cancer | Diseases
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2018, Volume 379, Issue 4, pp. 341 - 351
Among patients with advanced cutaneous squamous-cell carcinoma, the PD-1 inhibitor cemiplimab induced a response in approximately half the patients and was...
MISMATCH-REPAIR DEFICIENCY | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | NONMELANOMA SKIN-CANCER | SOLID TUMORS | LANDSCAPE | SENSITIVITY | CONSENSUS | TUMOR MUTATIONAL BURDEN | GUIDELINE | Skin Neoplasms - pathology | Skin Neoplasms - drug therapy | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Dose-Response Relationship, Drug | Disease-Free Survival | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Agents - adverse effects | Immunotherapy | Aged, 80 and over | Adult | Carcinoma, Squamous Cell - secondary | Female | Aged | Programmed Cell Death 1 Receptor - immunology | Neoplasm Staging | Monoclonal antibodies | Squamous cell carcinoma | Dosage and administration | Safety and security measures | Drug therapy | Intravenous administration | PD-1 protein | Body weight | Oncology | Metastasis | Cancer therapies | Metastases | Surgery | Constipation | Drug dosages | Departments | Statistical analysis | Dermatology | Diarrhea | Fatigue | Nausea | Patients | Medicine | Studies | Immunosuppression | Hospitals | Immune checkpoint | Womens health | Response rates | Skin | Health risk assessment | Tumors
MISMATCH-REPAIR DEFICIENCY | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | NONMELANOMA SKIN-CANCER | SOLID TUMORS | LANDSCAPE | SENSITIVITY | CONSENSUS | TUMOR MUTATIONAL BURDEN | GUIDELINE | Skin Neoplasms - pathology | Skin Neoplasms - drug therapy | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Dose-Response Relationship, Drug | Disease-Free Survival | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Agents - adverse effects | Immunotherapy | Aged, 80 and over | Adult | Carcinoma, Squamous Cell - secondary | Female | Aged | Programmed Cell Death 1 Receptor - immunology | Neoplasm Staging | Monoclonal antibodies | Squamous cell carcinoma | Dosage and administration | Safety and security measures | Drug therapy | Intravenous administration | PD-1 protein | Body weight | Oncology | Metastasis | Cancer therapies | Metastases | Surgery | Constipation | Drug dosages | Departments | Statistical analysis | Dermatology | Diarrhea | Fatigue | Nausea | Patients | Medicine | Studies | Immunosuppression | Hospitals | Immune checkpoint | Womens health | Response rates | Skin | Health risk assessment | Tumors
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 10/2014, Volume 32, Issue 30, pp. 3349 - 3352
SURVIVAL | OROPHARYNGEAL | RISK-FACTOR | ONCOLOGY | RECURRENT | METASTASES | SQUAMOUS-CELL CARCINOMA | HPV-RELATED HEAD | TRENDS | CHEMOTHERAPY | Carcinoma, Squamous Cell - virology | Humans | Female | Male | Neoplasm Proteins - analysis | Oropharyngeal Neoplasms - virology | Papillomaviridae - isolation & purification | Cyclin-Dependent Kinase Inhibitor p16
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2012, Volume 82, Issue 1, pp. 291 - 298
Purpose To update the Memorial Sloan-Kettering Cancer Center’s experience with intensity-modulated radiotherapy (IMRT) in the treatment of oropharyngeal cancer...
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Dysphagia | IMRT | Xerostomia | Oropharyngeal cancer | HEAD | SPARING RADIOTHERAPY | NECK-CANCER | RADIATION-THERAPY | SALIVARY-GLAND FUNCTION | IMPACT | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | QUALITY-OF-LIFE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Pharyngeal Neoplasms - radiotherapy | Follow-Up Studies | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Palate, Soft | Male | Oropharyngeal Neoplasms - pathology | Pharyngeal Neoplasms - drug therapy | Tongue Neoplasms - drug therapy | Incidence | New York City | Palatal Neoplasms - mortality | Treatment Failure | Aged, 80 and over | Adult | Female | Xerostomia - epidemiology | Tongue Neoplasms - radiotherapy | Radiotherapy Dosage | Tongue Neoplasms - mortality | Tonsillar Neoplasms - pathology | Oropharyngeal Neoplasms - drug therapy | Palatal Neoplasms - radiotherapy | Deglutition Disorders - epidemiology | Palatal Neoplasms - pathology | Oropharyngeal Neoplasms - radiotherapy | Cancer Care Facilities | Tonsillar Neoplasms - mortality | Tongue Neoplasms - pathology | Pharyngeal Neoplasms - mortality | Analysis of Variance | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Tonsillar Neoplasms - radiotherapy | Tonsillar Neoplasms - drug therapy | Pharyngeal Neoplasms - pathology | Aged | Palatal Neoplasms - drug therapy | Neoplasm Staging | Radiotherapy, Intensity-Modulated | Care and treatment | Throat cancer | Radiotherapy | Nuclear radiation | Cancer | PATIENTS | NEOPLASMS | FAILURES | METASTASES | PLATINUM | RADIATION DOSES | LYMPHATIC SYSTEM | CHEMOTHERAPY | PLANNING | PHARYNX | TONGUE | WOMEN | MEN | RADIOLOGY AND NUCLEAR MEDICINE | NECK | RADIOTHERAPY
Radiology | Hematology, Oncology and Palliative Medicine | Head-and-neck cancer | Dysphagia | IMRT | Xerostomia | Oropharyngeal cancer | HEAD | SPARING RADIOTHERAPY | NECK-CANCER | RADIATION-THERAPY | SALIVARY-GLAND FUNCTION | IMPACT | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | QUALITY-OF-LIFE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Pharyngeal Neoplasms - radiotherapy | Follow-Up Studies | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Palate, Soft | Male | Oropharyngeal Neoplasms - pathology | Pharyngeal Neoplasms - drug therapy | Tongue Neoplasms - drug therapy | Incidence | New York City | Palatal Neoplasms - mortality | Treatment Failure | Aged, 80 and over | Adult | Female | Xerostomia - epidemiology | Tongue Neoplasms - radiotherapy | Radiotherapy Dosage | Tongue Neoplasms - mortality | Tonsillar Neoplasms - pathology | Oropharyngeal Neoplasms - drug therapy | Palatal Neoplasms - radiotherapy | Deglutition Disorders - epidemiology | Palatal Neoplasms - pathology | Oropharyngeal Neoplasms - radiotherapy | Cancer Care Facilities | Tonsillar Neoplasms - mortality | Tongue Neoplasms - pathology | Pharyngeal Neoplasms - mortality | Analysis of Variance | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Tonsillar Neoplasms - radiotherapy | Tonsillar Neoplasms - drug therapy | Pharyngeal Neoplasms - pathology | Aged | Palatal Neoplasms - drug therapy | Neoplasm Staging | Radiotherapy, Intensity-Modulated | Care and treatment | Throat cancer | Radiotherapy | Nuclear radiation | Cancer | PATIENTS | NEOPLASMS | FAILURES | METASTASES | PLATINUM | RADIATION DOSES | LYMPHATIC SYSTEM | CHEMOTHERAPY | PLANNING | PHARYNX | TONGUE | WOMEN | MEN | RADIOLOGY AND NUCLEAR MEDICINE | NECK | RADIOTHERAPY
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e21033 - e21033
Journal Article
Cancer, ISSN 0008-543X, 11/2017, Volume 123, Issue 21, pp. 4114 - 4121
BACKGROUND Patients with recurrent and/or metastatic, radioactive iodine‐refractory thyroid carcinoma have limited treatment options. Sorafenib, an oral kinase...
anaplastic thyroid cancer | v‐Raf murine sarcoma viral oncogene homolog B (BRAF) mutation | thyroid cancer | sorafenib | mammalian target of rapamycin (mTOR) inhibition | v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutation | BROAD-SPECTRUM | II TRIAL | MTOR | LENVATINIB | ONCOLOGY | HISTOLOGIC SUBTYPES | DOUBLE-BLIND | TARGETS | CARCINOMA | PROGRESSION | Niacinamide - analogs & derivatives | Adenocarcinoma, Follicular - radiotherapy | Adenocarcinoma, Follicular - pathology | Humans | Middle Aged | Radiation Tolerance | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Adenocarcinoma, Follicular - genetics | Male | Antineoplastic Agents - therapeutic use | Iodine Radioisotopes - therapeutic use | Antineoplastic Agents - adverse effects | Phenylurea Compounds - adverse effects | Adenocarcinoma, Follicular - drug therapy | Aged, 80 and over | Adult | Female | Sirolimus - adverse effects | Sirolimus - analogs & derivatives | Drug Administration Schedule | Niacinamide - adverse effects | Treatment Outcome | Thyroid Neoplasms - radiotherapy | Niacinamide - administration & dosage | Disease-Free Survival | Sirolimus - administration & dosage | Thyroid Neoplasms - genetics | Phenylurea Compounds - administration & dosage | Thyroid Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Aged | Mutation | Thyroid Neoplasms - pathology | Temsirolimus | Cancer patients | Care and treatment | Dosage and administration | Thyroid cancer | Drug therapy | TOR protein | Intravenous administration | Mucositis | Toxicity | Anemia | Cytotoxicity | Fatigue | Rapamycin | Metastasis | Cancer therapies | Patients | Metastases | Thyroid carcinoma | Hyperglycemia | Chemotherapy | Inhibitors | Quality | Response rates | Background radiation | Iodine | Cancer | Thyroid | Index Medicus | Abridged Index Medicus
anaplastic thyroid cancer | v‐Raf murine sarcoma viral oncogene homolog B (BRAF) mutation | thyroid cancer | sorafenib | mammalian target of rapamycin (mTOR) inhibition | v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutation | BROAD-SPECTRUM | II TRIAL | MTOR | LENVATINIB | ONCOLOGY | HISTOLOGIC SUBTYPES | DOUBLE-BLIND | TARGETS | CARCINOMA | PROGRESSION | Niacinamide - analogs & derivatives | Adenocarcinoma, Follicular - radiotherapy | Adenocarcinoma, Follicular - pathology | Humans | Middle Aged | Radiation Tolerance | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Adenocarcinoma, Follicular - genetics | Male | Antineoplastic Agents - therapeutic use | Iodine Radioisotopes - therapeutic use | Antineoplastic Agents - adverse effects | Phenylurea Compounds - adverse effects | Adenocarcinoma, Follicular - drug therapy | Aged, 80 and over | Adult | Female | Sirolimus - adverse effects | Sirolimus - analogs & derivatives | Drug Administration Schedule | Niacinamide - adverse effects | Treatment Outcome | Thyroid Neoplasms - radiotherapy | Niacinamide - administration & dosage | Disease-Free Survival | Sirolimus - administration & dosage | Thyroid Neoplasms - genetics | Phenylurea Compounds - administration & dosage | Thyroid Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Aged | Mutation | Thyroid Neoplasms - pathology | Temsirolimus | Cancer patients | Care and treatment | Dosage and administration | Thyroid cancer | Drug therapy | TOR protein | Intravenous administration | Mucositis | Toxicity | Anemia | Cytotoxicity | Fatigue | Rapamycin | Metastasis | Cancer therapies | Patients | Metastases | Thyroid carcinoma | Hyperglycemia | Chemotherapy | Inhibitors | Quality | Response rates | Background radiation | Iodine | Cancer | Thyroid | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2015, Volume 33, Issue 15, pp. 1710 - 1710
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 04/2012, Volume 82, Issue 5, pp. 1837 - 1844
Purpose Dynamic contrast-enhanced MRI (DCE-MRI) can provide information regarding tumor perfusion and permeability and has shown prognostic value in certain...
Radiology | Hematology, Oncology and Palliative Medicine | Dynamic contrast enhanced MRI (DCE-MRI) | Volume transfer constant (Ktrans) | Head and neck squamous cell carcinoma (HNSCC) | Volume transfer constant (K-trans) | Volume transfer constant (K | FDG-PET | SURVIVAL | LARYNGEAL-CANCER | INTENSITY-MODULATED RADIOTHERAPY | BLOOD-VOLUME | CHEMOTHERAPY | BREAST | PROGNOSTIC-FACTOR | THERAPY | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | TUMOR VOLUME | Oropharyngeal Neoplasms - therapy | Follow-Up Studies | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Magnetic Resonance Imaging - methods | Male | Oropharyngeal Neoplasms - secondary | Oropharyngeal Neoplasms - pathology | Carcinoma, Squamous Cell - diagnosis | Mouth Neoplasms - diagnosis | Carcinoma, Squamous Cell - mortality | Statistics, Nonparametric | Aged, 80 and over | Adult | Female | Retrospective Studies | Oropharyngeal Neoplasms - diagnosis | Chemoradiotherapy - methods | Proportional Hazards Models | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Lymphatic Metastasis | Mouth Neoplasms - mortality | Mouth Neoplasms - therapy | Disease-Free Survival | Contrast Media | Analysis of Variance | Mouth Neoplasms - pathology | Carcinoma, Squamous Cell - secondary | Aged | Mouth Neoplasms - secondary | Neoplasm Staging | Gadolinium DTPA | Squamous cell carcinoma | Carcinoma | Magnetic resonance imaging | Nuclear radiation | Patient outcomes | Radiation | Diagnostic imaging | Metastasis | Permeability | Cancer | Tumors | SURGERY | HEAD | PATIENTS | NMR IMAGING | PERMEABILITY | STATISTICS | METASTASES | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | HAZARDS | Dynamic Contrast Enhanced-MRI (DCE-MRI) | volume transfer constant (Ktrans) | head and neck squamous cell carcinoma (HNSCC)
Radiology | Hematology, Oncology and Palliative Medicine | Dynamic contrast enhanced MRI (DCE-MRI) | Volume transfer constant (Ktrans) | Head and neck squamous cell carcinoma (HNSCC) | Volume transfer constant (K-trans) | Volume transfer constant (K | FDG-PET | SURVIVAL | LARYNGEAL-CANCER | INTENSITY-MODULATED RADIOTHERAPY | BLOOD-VOLUME | CHEMOTHERAPY | BREAST | PROGNOSTIC-FACTOR | THERAPY | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | TUMOR VOLUME | Oropharyngeal Neoplasms - therapy | Follow-Up Studies | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Oropharyngeal Neoplasms - mortality | Magnetic Resonance Imaging - methods | Male | Oropharyngeal Neoplasms - secondary | Oropharyngeal Neoplasms - pathology | Carcinoma, Squamous Cell - diagnosis | Mouth Neoplasms - diagnosis | Carcinoma, Squamous Cell - mortality | Statistics, Nonparametric | Aged, 80 and over | Adult | Female | Retrospective Studies | Oropharyngeal Neoplasms - diagnosis | Chemoradiotherapy - methods | Proportional Hazards Models | Carcinoma, Squamous Cell - therapy | Treatment Outcome | Lymphatic Metastasis | Mouth Neoplasms - mortality | Mouth Neoplasms - therapy | Disease-Free Survival | Contrast Media | Analysis of Variance | Mouth Neoplasms - pathology | Carcinoma, Squamous Cell - secondary | Aged | Mouth Neoplasms - secondary | Neoplasm Staging | Gadolinium DTPA | Squamous cell carcinoma | Carcinoma | Magnetic resonance imaging | Nuclear radiation | Patient outcomes | Radiation | Diagnostic imaging | Metastasis | Permeability | Cancer | Tumors | SURGERY | HEAD | PATIENTS | NMR IMAGING | PERMEABILITY | STATISTICS | METASTASES | CARCINOMAS | RADIOLOGY AND NUCLEAR MEDICINE | NECK | HAZARDS | Dynamic Contrast Enhanced-MRI (DCE-MRI) | volume transfer constant (Ktrans) | head and neck squamous cell carcinoma (HNSCC)
Journal Article
International Journal of Radiation OncologyBiologyPhysics, ISSN 0360-3016, 10/2019
Journal Article
Cancer, ISSN 0008-543X, 05/2013, Volume 119, Issue 10, pp. 1823 - 1831
BACKGROUND: Activation of the phosphatidylinositol‐3‐kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway is common in head and neck cancers, and it...
phase 1 | everolimus | squamous | induction | neck | MAMMALIAN TARGET | ADVANCED SOLID TUMORS | INHIBITOR EVEROLIMUS | COMBINATION | MTOR | PACLITAXEL | ONCOLOGY | UNRESECTABLE HEAD | METASTATIC BREAST-CANCER | RAPAMYCIN INHIBITOR | SQUAMOUS-CELL CANCER | Smoking - adverse effects | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Phosphatidylinositol 3-Kinases - metabolism | Head and Neck Neoplasms - metabolism | Cisplatin - administration & dosage | Adult | Female | Proto-Oncogene Proteins c-akt - metabolism | Everolimus | Papillomavirus Infections - complications | Sirolimus - analogs & derivatives | Drug Administration Schedule | Risk Assessment | Risk Factors | Head and Neck Neoplasms - drug therapy | Induction Chemotherapy - methods | Treatment Outcome | Head and Neck Neoplasms - pathology | Induction Chemotherapy - adverse effects | Disease-Free Survival | Sirolimus - administration & dosage | Taxoids - administration & dosage | Maximum Tolerated Dose | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Mutation | Neoplasm Staging | Head and neck cancer | Chemotherapy | Usage | Care and treatment | Drug therapy, Combination | Cancer | Index Medicus | Abridged Index Medicus
phase 1 | everolimus | squamous | induction | neck | MAMMALIAN TARGET | ADVANCED SOLID TUMORS | INHIBITOR EVEROLIMUS | COMBINATION | MTOR | PACLITAXEL | ONCOLOGY | UNRESECTABLE HEAD | METASTATIC BREAST-CANCER | RAPAMYCIN INHIBITOR | SQUAMOUS-CELL CANCER | Smoking - adverse effects | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Phosphatidylinositol 3-Kinases - metabolism | Head and Neck Neoplasms - metabolism | Cisplatin - administration & dosage | Adult | Female | Proto-Oncogene Proteins c-akt - metabolism | Everolimus | Papillomavirus Infections - complications | Sirolimus - analogs & derivatives | Drug Administration Schedule | Risk Assessment | Risk Factors | Head and Neck Neoplasms - drug therapy | Induction Chemotherapy - methods | Treatment Outcome | Head and Neck Neoplasms - pathology | Induction Chemotherapy - adverse effects | Disease-Free Survival | Sirolimus - administration & dosage | Taxoids - administration & dosage | Maximum Tolerated Dose | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Mutation | Neoplasm Staging | Head and neck cancer | Chemotherapy | Usage | Care and treatment | Drug therapy, Combination | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Cancer, ISSN 0008-543X, 11/2017, Volume 123, Issue 21, pp. 4114 - 4121
Journal Article
Head & Neck, ISSN 1043-3074, 02/2018, Volume 40, Issue 2, pp. 233 - 241
Background The human papillomavirus (HPV) E6 oncoprotein enhances the oncogenic potential of ErbB proteins in HPV‐related malignancies. This phase I study...
afatinib | ribavirin | oropharyngeal cancer | human papillomavirus | squamous cell carcinoma | TRANSFORMATION | SURGERY | HEAD | BINDING MOTIF | PROTEIN | MESSENGER-RNA CAP | TYPE-16 | CERVICAL NEOPLASIA | NECK-CANCER | OTORHINOLARYNGOLOGY | EIF4E | CARCINOMA | Afatinib - administration & dosage | Oropharyngeal Neoplasms - drug therapy | Papillomavirus Infections - complications | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Carboplatin - administration & dosage | Induction Chemotherapy | Male | Oropharyngeal Neoplasms - virology | Papillomaviridae - isolation & purification | Antiviral Agents - administration & dosage | Dose-Response Relationship, Drug | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Progression-Free Survival | Ribavirin - administration & dosage | Papillomavirus Infections - drug therapy | Aged | Neoplasm Staging | Paclitaxel - administration & dosage | Papillomaviruses | Proteins | Chemotherapy | Squamous cell carcinoma | Paclitaxel | Papillomavirus infections | Ribavirin | Cancer | Human papillomavirus | Toxicity | ErbB protein | Carboplatin | Index Medicus
afatinib | ribavirin | oropharyngeal cancer | human papillomavirus | squamous cell carcinoma | TRANSFORMATION | SURGERY | HEAD | BINDING MOTIF | PROTEIN | MESSENGER-RNA CAP | TYPE-16 | CERVICAL NEOPLASIA | NECK-CANCER | OTORHINOLARYNGOLOGY | EIF4E | CARCINOMA | Afatinib - administration & dosage | Oropharyngeal Neoplasms - drug therapy | Papillomavirus Infections - complications | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Carboplatin - administration & dosage | Induction Chemotherapy | Male | Oropharyngeal Neoplasms - virology | Papillomaviridae - isolation & purification | Antiviral Agents - administration & dosage | Dose-Response Relationship, Drug | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Progression-Free Survival | Ribavirin - administration & dosage | Papillomavirus Infections - drug therapy | Aged | Neoplasm Staging | Paclitaxel - administration & dosage | Papillomaviruses | Proteins | Chemotherapy | Squamous cell carcinoma | Paclitaxel | Papillomavirus infections | Ribavirin | Cancer | Human papillomavirus | Toxicity | ErbB protein | Carboplatin | Index Medicus
Journal Article
Journal for ImmunoTherapy of Cancer, ISSN 2051-1426, 11/2016, Volume 4, Issue 1, p. 70
Background: Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (CSCC) share exposure to UV light as the dominant risk factor, and these tumors...
Basal cell carcinoma | Cutaneous squamous cell carcinoma | Immune checkpoint inhibitor | Mutation burden | REGN2810 | Programmed Death-1 | Phase 1 | SKIN CANCERS | ONCOLOGY | PD-1 BLOCKADE | IMMUNOLOGY | Skin Neoplasms - pathology | Skin Neoplasms - drug therapy | Antibodies, Monoclonal - pharmacology | Carcinoma, Squamous Cell - metabolism | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Tomography, X-Ray Computed | Treatment Outcome | Carcinoma, Basal Cell - metabolism | Antineoplastic Agents, Immunological - pharmacology | Carcinoma, Basal Cell - diagnosis | Carcinoma, Squamous Cell - diagnosis | Neoplasm Metastasis | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Agents, Immunological - therapeutic use | Skin Neoplasms - diagnosis | Carcinoma, Basal Cell - drug therapy | Female | Aged | Neoplasm Staging | Squamous cell carcinoma | Care and treatment | Monoclonal antibodies | Development and progression | Research | Health aspects | Risk factors | Consent | Funding | Mutation | Metastasis | Drug dosages | Patients | Manuscripts | Deoxyribonucleic acid--DNA | Pharmaceuticals | Tumors
Basal cell carcinoma | Cutaneous squamous cell carcinoma | Immune checkpoint inhibitor | Mutation burden | REGN2810 | Programmed Death-1 | Phase 1 | SKIN CANCERS | ONCOLOGY | PD-1 BLOCKADE | IMMUNOLOGY | Skin Neoplasms - pathology | Skin Neoplasms - drug therapy | Antibodies, Monoclonal - pharmacology | Carcinoma, Squamous Cell - metabolism | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Tomography, X-Ray Computed | Treatment Outcome | Carcinoma, Basal Cell - metabolism | Antineoplastic Agents, Immunological - pharmacology | Carcinoma, Basal Cell - diagnosis | Carcinoma, Squamous Cell - diagnosis | Neoplasm Metastasis | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Agents, Immunological - therapeutic use | Skin Neoplasms - diagnosis | Carcinoma, Basal Cell - drug therapy | Female | Aged | Neoplasm Staging | Squamous cell carcinoma | Care and treatment | Monoclonal antibodies | Development and progression | Research | Health aspects | Risk factors | Consent | Funding | Mutation | Metastasis | Drug dosages | Patients | Manuscripts | Deoxyribonucleic acid--DNA | Pharmaceuticals | Tumors
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. e18703 - e18703
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2017, Volume 35, Issue 15_suppl, pp. 6081 - 6081
Journal Article
International Journal of Radiation Oncology Biology Physics, ISSN 0360-3016, 01/2012, Volume 82, Issue 1, pp. 299 - 307
Purpose: To correlate proton magnetic resonance spectroscopy (H-1-MRS), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and F-18-labeled...
Proton magnetic resonance spectroscopy | Dynamic contrast-enhanced MRI | Head and neck squamous cell carcinoma | Short-term treatment response | [F-18]FDG-PET | FDG-PET | PARAMETERS | PROGNOSTIC VALUE | CANCER | F-18-FDG PET | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | RADIATION TREATMENT | LYMPHOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Proton magnetic resonance spectroscopy | Dynamic contrast-enhanced MRI | Head and neck squamous cell carcinoma | Short-term treatment response | [F-18]FDG-PET | FDG-PET | PARAMETERS | PROGNOSTIC VALUE | CANCER | F-18-FDG PET | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | RADIATION TREATMENT | LYMPHOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
Cancer, ISSN 0008-543X, 10/2012, Volume 118, Issue 20, pp. 5008 - 5014
BACKGROUND: For patients with stage III through IVB head and neck squamous cell carcinoma (HNSCC), concurrent high‐dose cisplatin plus radiation therapy is a...
bevacizumab | head and neck | phase 2 | cisplatin | radiation | HYDROXYUREA | HUMAN-PAPILLOMAVIRUS | II TRIAL | CHEMOTHERAPY | ONCOLOGY | RADIOTHERAPY | CARCINOMA | CONCURRENT CHEMORADIOTHERAPY | ENDOTHELIAL GROWTH-FACTOR | Humans | Middle Aged | Head and Neck Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Combined Modality Therapy | Carcinoma, Squamous Cell - radiotherapy | Bevacizumab | Cisplatin - administration & dosage | Disease-Free Survival | Head and Neck Neoplasms - radiotherapy | Antibodies, Monoclonal, Humanized - administration & dosage | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adult | Female | Aged | Radiotherapy, Intensity-Modulated | Dose-response relationship (Biochemistry) | Care and treatment | Usage | Patient outcomes | Head and neck cancer | Dosage and administration | Drug therapy | Radiotherapy | Cisplatin | Methods | Cancer | Index Medicus | Abridged Index Medicus
bevacizumab | head and neck | phase 2 | cisplatin | radiation | HYDROXYUREA | HUMAN-PAPILLOMAVIRUS | II TRIAL | CHEMOTHERAPY | ONCOLOGY | RADIOTHERAPY | CARCINOMA | CONCURRENT CHEMORADIOTHERAPY | ENDOTHELIAL GROWTH-FACTOR | Humans | Middle Aged | Head and Neck Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Combined Modality Therapy | Carcinoma, Squamous Cell - radiotherapy | Bevacizumab | Cisplatin - administration & dosage | Disease-Free Survival | Head and Neck Neoplasms - radiotherapy | Antibodies, Monoclonal, Humanized - administration & dosage | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adult | Female | Aged | Radiotherapy, Intensity-Modulated | Dose-response relationship (Biochemistry) | Care and treatment | Usage | Patient outcomes | Head and neck cancer | Dosage and administration | Drug therapy | Radiotherapy | Cisplatin | Methods | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 77, Issue 5, pp. 1403 - 1410
To assess noninvasively the tumor microenvironment of neck nodal metastases in patients with head-and-neck cancer by investigating the relationship between...
Dynamic contrast-enhanced-MRI (DCE-MRI) | Head-and-neck cancer | 18F-FMISO PET | 18F-FDG | Humans | Middle Aged | Male | Lymphatic Metastasis | Positron-Emission Tomography | Lymph Nodes | Head and Neck Neoplasms | Journal Article | Research Support, N.I.H., Extramural | Carcinoma, Squamous Cell | Cell Hypoxia | Magnetic Resonance Imaging | Misonidazole | Statistics, Nonparametric | Aged, 80 and over | Female | Aged | Retrospective Studies | Radiopharmaceuticals | F-FMISO PET | F-FDG | Cell Hypoxia - physiology | Lymph Nodes - pathology | Radiopharmaceuticals - pharmacokinetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Head and Neck Neoplasms - diagnostic imaging | Lymph Nodes - metabolism | Magnetic Resonance Imaging - methods | Carcinoma, Squamous Cell - diagnostic imaging | Misonidazole - pharmacokinetics | Misonidazole - analogs & derivatives | Positron-Emission Tomography - methods | Head and Neck Neoplasms - metabolism | Head and Neck Neoplasms - pathology | Lymph Nodes - diagnostic imaging
Dynamic contrast-enhanced-MRI (DCE-MRI) | Head-and-neck cancer | 18F-FMISO PET | 18F-FDG | Humans | Middle Aged | Male | Lymphatic Metastasis | Positron-Emission Tomography | Lymph Nodes | Head and Neck Neoplasms | Journal Article | Research Support, N.I.H., Extramural | Carcinoma, Squamous Cell | Cell Hypoxia | Magnetic Resonance Imaging | Misonidazole | Statistics, Nonparametric | Aged, 80 and over | Female | Aged | Retrospective Studies | Radiopharmaceuticals | F-FMISO PET | F-FDG | Cell Hypoxia - physiology | Lymph Nodes - pathology | Radiopharmaceuticals - pharmacokinetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Head and Neck Neoplasms - diagnostic imaging | Lymph Nodes - metabolism | Magnetic Resonance Imaging - methods | Carcinoma, Squamous Cell - diagnostic imaging | Misonidazole - pharmacokinetics | Misonidazole - analogs & derivatives | Positron-Emission Tomography - methods | Head and Neck Neoplasms - metabolism | Head and Neck Neoplasms - pathology | Lymph Nodes - diagnostic imaging
Journal Article