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PLOS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0165214 - e0165214
Background There is great interest in repurposing the commonly prescribed anti-diabetic drug metformin for cancer therapy. Intracellular uptake and retention... 
DIABETES-MELLITUS | BREAST-CANCER | GENETIC-VARIATION | POLYMORPHISMS | TUMOR HYPOXIA | VARIANTS | RENAL CLEARANCE | POPULATION PHARMACOKINETICS | MULTIDISCIPLINARY SCIENCES | CATION TRANSPORTER 1 | THERAPEUTIC RESPONSE | Metformin - therapeutic use | Humans | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Octamer Transcription Factors - genetics | Biomarkers, Tumor - metabolism | Antineoplastic Agents - pharmacology | Octamer Transcription Factors - metabolism | Hypoglycemic Agents - therapeutic use | Organic Cation Transport Proteins - metabolism | HCT116 Cells | Metformin - pharmacology | Cells, Cultured | Mice, SCID | Hypoglycemic Agents - pharmacology | Animals | Oxygen Consumption - drug effects | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Mice | HeLa Cells | Neoplasms, Experimental - metabolism | Organic Cation Transport Proteins - genetics | Neoplasms, Experimental - drug therapy | Complications and side effects | Care and treatment | Dosage and administration | Research | Metformin | Diabetes therapy | Cancer | Biotechnology | Oct-4 protein | Radiation | Science | Clinical trials | Oncology | Oct-2 protein | Cancer therapies | Mitochondria | Health care networks | Inhibition | Drug dosages | Medical research | Oxygen | Statistical analysis | Diabetes mellitus | Oxygen consumption | Breast cancer | Radiation therapy | Biophysics | Tumor cell lines | Gene expression | Sensitivity | Biomarkers | Hypoxia | Extrusion | Intracellular | Diabetes | Respiration | Oxygenation | Tumors | Index Medicus
Journal Article
Molecular Therapy, ISSN 1525-0016, 09/2018, Volume 26, Issue 9, pp. 2315 - 2325
The approval of the first oncolytic virus for the treatment of metastatic melanoma and the compiling evidence that the use of oncolytic viruses can enhance... 
viruses | cancer | immunotherapy | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | ADVANCED MELANOMA PATIENTS | TUMOR-INFILTRATING LYMPHOCYTES | TRIAL | IMMUNOGENICITY | BENEFIT | PHASE | T-CELL RESPONSES | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | IPILIMUMAB | Original
Journal Article
JOURNAL FOR IMMUNOTHERAPY OF CANCER, ISSN 2051-1426, 07/2019, Volume 7, Issue 1, pp. 174 - 14
Background: DNA vaccines against cancer held great promises due to the generation of a specific and long lasting immune response. However, when used as a... 
DNA vaccine | INTERLEUKIN-2 | RECRUITMENT | NATURAL-KILLER-CELLS | ACTIVATION | Melanoma neoantigens | Tumor microenvironment | EFFICACY | RECEPTOR | IMMUNOLOGY | IDENTIFICATION | Oncolytic adenovirus | THERAPY | NK CELLS | ONCOLOGY | Cancer | Usage | Care and treatment | Immune response | Adenoviruses | Genetic aspects | Research | Vaccines
Journal Article
ACS NANO, ISSN 1936-0851, 06/2019, Volume 13, Issue 6, pp. 6477 - 6490
Recent approaches in the treatment of cancer focus on involving the immune system to control the tumor growth. The administration of immunotherapies, like... 
IMMUNE CELLS | EFFICACY | cancer vaccine | MATERIALS SCIENCE, MULTIDISCIPLINARY | cell membrane | CHEMISTRY, PHYSICAL | melanoma | NANOSCIENCE & NANOTECHNOLOGY | CANCER-IMMUNOTHERAPY | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | NANOPARTICLES | TUMOR-CELL VACCINE | biohybrid | BLOCKADE | microfluidics | ACETALATED DEXTRAN | SURFACE-CHEMISTRY | ANTIGEN
Journal Article
NANOSCALE, ISSN 2040-3364, 01/2020, Volume 12, Issue 4, pp. 2350 - 2358
The advent of nanomedicine has recently started to innovate the treatment of cardiovascular diseases, in particular myocardial infarction. Although current... 
DRUG | CELLS | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOSCIENCE & NANOTECHNOLOGY | PROLIFERATION | MICROPARTICLES | ENDOCYTOSIS | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | DELIVERY | MURINE MODEL | IN-VITRO | PROTEIN RELEASE
Journal Article
OncoImmunology, ISSN 2162-4011, 09/2017, Volume 6, Issue 9, p. e1319028
Tolerance toward tumor antigens, which are shared by normal tissues, have often limited the efficacy of cancer vaccines. However, wild type epitopes can be... 
heteroclitic peptides | Cancer vaccine | in silico | tumor antigens | prediction servers | immunotherapy | PEPTIDE LIGANDS | STIMULATION | TYROSINASE | VACCINE | IMMUNOLOGY | IDENTIFICATION | PREDICTION | ONCOLOGY | IMMUNE-RESPONSES | CROSS-REACTIVITY | MELAN-A/MART-1 | T-CELLS
Journal Article
Cancer research, ISSN 0008-5472, 02/2020, p. canres.2062.2019
Due to the high coverage of international vaccination programs, most people worldwide have been vaccinated against common pathogens, leading to acquired... 
Journal Article
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