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PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, pp. e0124234 - e0124234
Emerging evidence suggests that the vascular endothelial growth factor receptor 2 (VEGFR2) and protein kinase D1 (PKD1) signaling axis plays a critical role in... 
INDUCED GENE-EXPRESSION | PERMANENT CELL-LINE | VIVO | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | MAST-CELLS | DRUG DISCOVERY | D ACTIVATION | NEUTROPHILS | MOLECULAR-CLONING | FAMILY | Cell Line | Cell Survival - drug effects | Protein Kinase C - genetics | Humans | Neutrophils - drug effects | Neovascularization, Pathologic | Neutrophils - immunology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Protein Kinase C - antagonists & inhibitors | Pyrimidines - chemistry | Vascular Endothelial Growth Factor Receptor-2 - genetics | Cell Movement - drug effects | Vascular Endothelial Growth Factor Receptor-2 - antagonists & inhibitors | Pyrimidines - toxicity | Signal Transduction - drug effects | Protein Kinase C - metabolism | Pyridones - toxicity | Superoxides - metabolism | Protein Kinase Inhibitors - toxicity | Cell Proliferation - drug effects | Pyridones - chemistry | Neutrophils - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Fibrin | Cell research | Fibrinogen | Inflammation | Comparative analysis | Vascular endothelial growth factor | Health aspects | Protein kinases | Cell proliferation | Motility | Peptides | Leukocyte migration | Laboratories | Intracellular signalling | Activation | Kinases | Assaying | Cancer therapies | Inflammatory diseases | Proteins | Angiogenesis | Signal transduction | Cell activation | Cell growth | Immunology | Pathways | Physiology | Inhibition | Vascular endothelial growth factor receptor 2 | Growth factors | Recombinant | Medical research | Therapeutic applications | Neutrophils | Leukocytes (neutrophilic) | Tumor necrosis factor-α | Gene expression | Endothelial cells | Endothelium | Chemistry | Inhibitors | Protein kinase | Rheumatoid arthritis | Degranulation | Mast cells | Angiogenesis inhibitors | Molecular biology | Cell migration | Index Medicus
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2019, Volume 10, pp. 252 - 252
Activating Fc gamma receptors associated with Fc receptor gamma-chain (FcR gamma) are critical for mediating neutrophil effector functions in immune... 
Fc receptors | Fc receptor γ-chain | autoimmune arthritis | ITAM tyrosines | neutrophils | Fc receptor gamma-chain | MACROPHAGES | MAST-CELLS | MOUSE | IMMUNOLOGY | DELETION | FAMILY | RESPONSES | INFLAMMATION | GENERATION | SECRETION | EXPRESSION
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e87104 - e87104
Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this... 
KINASE PATHWAYS | ACTIVATION | GENE | INITIATION | MULTIDISCIPLINARY SCIENCES | SERINE PROTEASE-1 MASP-1 | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | LECTIN-PATHWAY | NF-KAPPA-B | EXPRESSION | INTERLEUKIN-8 | Chemotaxis, Leukocyte | Complement Activation | Cytokines - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Neutrophil Activation | Mannose-Binding Protein-Associated Serine Proteases - physiology | Humans | Cells, Cultured | Cytokines - secretion | Neutrophils - immunology | Human Umbilical Vein Endothelial Cells - immunology | Human Umbilical Vein Endothelial Cells - secretion | MAP Kinase Signaling System | MAP Kinase Kinase 4 - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Neutrophils - metabolism | Lectins | Enzymes | Thrombin | Cytokines | Health aspects | Endothelium | Phosphorylation | Serine | Activation | Complement | Interleukin 1 receptors | Kinases | Antiinfectives and antibacterials | Mannan | Cell adhesion & migration | Interleukin 6 | Proteins | Calcium signalling | Cell activation | Microorganisms | Cell growth | Granulocytes | Mannose-binding lectin | Physiology | Growth factors | Interleukin 8 | Immune system | Recombinant | Medical research | Pathogens | Internal medicine | Interleukin 1 receptor antagonist | Neutrophils | MAP kinase | Leukocytes (neutrophilic) | Chemotaxis | Endothelial cells | Medicine | Complement activation | Low density lipoprotein receptors | Serine proteinase | Kinetics | Leukocytes (granulocytic) | Umbilical vein | Binding sites | Cell migration | Chemokines | Monocyte chemoattractant protein 1 | MASP-1 protein | Index Medicus
Journal Article
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 12/2009, Volume 102, Issue 6, pp. 1265 - 1273
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2010, Volume 185, Issue 5, pp. 3064 - 3075
Journal Article
PLoS ONE, 01/2014, Volume 9, Issue 1
Microbial infection urges prompt intervention by the immune system. The complement cascade and neutrophil granulocytes are the predominant contributors to this... 
Journal Article
International Immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | HUMAN POLYMORPHONUCLEAR LEUKOCYTES | HIGH-AFFINITY RECEPTOR | TUMOR-NECROSIS-FACTOR | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | BETA-GAMMA-SUBUNITS | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | Index Medicus | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article