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by Chiesa, Patrizia A and Cavedo, Enrica and Vergallo, Andrea and Lista, Simone and Potier, Marie-Claude and Habert, Marie-Odile and Dubois, Bruno and Thiebaut de Schotten, Michel and Hampel, Harald and Bakardjian, Hovagim and Benali, Habib and Bertin, Hugo and Bonheur, Joel and Boukadida, Laurie and Boukerrou, Nadia and Cavedo, Enrica and Chiesa, Patrizia and Colliot, Olivier and Dubois, Bruno and Dubois, Marion and Epelbaum, Stéphane and Gagliardi, Geoffroy and Genthon, Remy and Habert, Marie-Odile and Hampel, Harald and Houot, Marion and Kas, Aurélie and Lamari, Foudil and Levy, Marcel and Lista, Simone and Metzinger, Christiane and Mochel, Fanny and Nyasse, Francis and Poisson, Catherine and Potier, Marie-Claude and Revillon, Marie and Santos, Antonio and Andrade, Katia Santos and Sole, Marine and Surtee, Mohmed and de Schotten, Michel Thiebaud and Vergallo, Andrea and Younsi, Nadjia and Afshar, Mohammad and Aguilar, Lisi Flores and Akman-Anderson, Leyla and Arenas, Joaquín and Avila, Jesus and Babiloni, Claudio and Baldacci, Filippo and Batrla, Richard and Benda, Norbert and Black, Keith L and Bokde, Arun L.W and Bonuccelli, Ubaldo and Broich, Karl and Cacciola, Francesco and Caraci, Filippo and Castrillo, Juan and Ceravolo, Roberto and Chiesa, Patrizia A and Corvol, Jean-Christophe and Cuello, Augusto Claudio and Cummings, Jeffrey L and Depypere, Herman and Duggento, Andrea and Emanuele, Enzo and Escott-Price, Valentina and Federoff, Howard and Ferretti, Maria Teresa and Fiandaca, Massimo and Frank, Richard A and Garaci, Francesco and Geerts, Hugo and Giorgi, Filippo S and Goetzl, Edward J and Graziani, Manuela and Haberkamp, Marion and Herholz, Karl and Hernandez, Felix and Kapogiannis, Dimitrios and Karran, Eric and Kiddle, Steven J and Kim, Seung H and Koronyo, Yosef and Koronyo-Hamaoui, Maya and Langevin, Todd and Lehéricy, Stéphane and Lucía, Alejandro and Lorenceau, Jean and Mango, Dalila and Mapstone, Mark and Neri, Christian and Nisticó, Robert and O’Bryant, Sid E and Palermo, Giovanni and Perry, George and Ritchie, Craig and Rossi, Simone and Saidi, Amira and ... and INSIGHT-preAD study group and Alzheimer Precision Medicine Initiative (APMI) and INSIGHT-preAD Study Grp and Alzheimer Precision Med Initiative and for theAlzheimer Precision Medicine Initiative (APMI) and and the INSIGHT-preAD study group
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2019, Volume 15, Issue 7, pp. 940 - 950
The longitudinal trajectories of functional brain dynamics and the impact of genetic risk factors in individuals at risk for Alzheimer's disease are poorly... 
fMRI | Brain functional dynamics | Subjective memory complaints | Precision medicine | Alzheimer's disease | BRAIN ACTIVITY | RESTING-STATE FMRI | BIOMARKER | FUNCTIONAL CONNECTIVITY | CLINICAL NEUROLOGY | INDEPENDENT COMPONENT ANALYSIS | APOLIPOPROTEIN-E | PRECUNEUS | MEMORY COMPLAINTS | APOE | ASSOCIATION | Neuroscience | Cognitive science
Journal Article
Journal Article
Alzheimer's Research & Therapy, ISSN 1758-9193, 12/2018, Volume 10, Issue 1, pp. 1 - 14
Abstract Background Despite a tremendous amount of information on the role of amyloid in Alzheimer’s disease (AD), almost all clinical trials testing this... 
Amyloid load | Trial failure | Amyloid secretase inhibition | Modeling | Patient selection | Biologics
Journal Article
by Vergallo, Andrea and Mégret, Lucile and Lista, Simone and Cavedo, Enrica and Zetterberg, Henrik and Blennow, Kaj and Vanmechelen, Eugeen and De Vos, Ann and Habert, Marie-Odile and Potier, Marie-Claude and Dubois, Bruno and Neri, Christian and Hampel, Harald and Bakardjian, H and Benali, H and Bertin, H and Bonheur, J and Boukadida, L and Boukerrou, N and Cavedo, E and Chiesa, P and Colliot, O and Dubois, B and Dubois, M and Epelbaum, S and Gagliardi, G and Genthon, R and Habert, M.O and Hampel, H and Houot, M and Kas, A and Lamari, F and Levy, M and Lista, S and Metzinger, C and Mochel, F and Nyasse, F and Poisson, C and Potier, M.C and Revillon, M and Santos, A and Andrade, K.S and Sole, M and Surtee, M and de Schotten M, Thiebaud and Vergallo, A and Younsi, N and Aguilar, Lisi Flores and Babiloni, Claudio and Baldacci, Filippo and Benda, Norbert and Black, Keith L and Bokde, Arun L.W and Bonuccelli, Ubaldo and Broich, Karl and Cacciola, Francesco and Castrillo, Juan and Cavedo, Enrica and Ceravolo, Roberto and Chiesa, Patrizia A and Corvol, Jean-Christophe and Cuello, Augusto Claudio and Cummings, Jeffrey L and Depypere, Herman and Dubois, Bruno and Duggento, Andrea and Escott-Price, Valentina and Federoff, Howard and Ferretti, Maria Teresa and Fiandaca, Massimo and Frank, Richard A and Garaci, Francesco and Geerts, Hugo and Giorgi, Filippo S and Graziani, Manuela and Haberkamp, Marion and Habert, Marie-Odile and Hampel, Harald and Herholz, Karl and Karran, Eric and Kim, Seung H and Koronyo, Yosef and Koronyo-Hamaoui, Maya and Lamari, Foudil and Langevin, Todd and Lehéricy, Stéphane and Lista, Simone and Lorenceau, Jean and Mango, Dalila and Mapstone, Mark and Neri, Christian and Nisticò, Robert and O'Bryant, Sid E and Perry, George and Ritchie, Craig and Rossi, Simone and Saidi, Amira and Santarnecchi, Emiliano and Schneider, Lon S and Sporns, Olaf and ... and INSIGHT-preAD study group and Alzheimer Precision Medicine Initiative (APMI) and and the INSIGHT-preAD study group and for the Alzheimer Precision Medicine Initiative (APMI) and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 06/2019, Volume 15, Issue 6, pp. 764 - 775
Blood-based biomarkers of pathophysiological brain amyloid β (Aβ) accumulation, particularly for preclinical target and large-scale interventions, are... 
Plasma amyloid β | Subjective memory complainers | Amyloid PET | Machine learning | Classification and regression trees (CART) | Alzheimer's disease | Simoa immunoassay | Neurosciences | decline | progression | Plasma amyloid beta | blood-based biomarkers | Subjective | Neurovetenskaper
Journal Article
by Toschi, Nicola and Lista, Simone and Baldacci, Filippo and Cavedo, Enrica and Zetterberg, Henrik and Blennow, Kaj and Kilimann, Ingo and Teipel, Stefan J and Melo dos Santos, Antonio and Epelbaum, Stéphane and Lamari, Foudil and Genthon, Remy and Habert, Marie-Odile and Dubois, Bruno and Floris, Roberto and Garaci, Francesco and Vergallo, Andrea and Hampel, Harald and Bakardjian, Hovagim and Benali, Habib and Bertin, Hugo and Bonheur, Joel and Boukadida, Laurie and Boukerrou, Nadia and Cavedo, Enrica and Chiesa, Patrizia and Colliot, Olivier and Dubois, Bruno and Dubois, Marion and Epelbaum, Stéphane and Gagliardi, Geoffroy and Genthon, Remy and Habert, Marie-Odile and Hampel, Harald and Houot, Marion and Kas, Aurélie and Lamari, Foudil and Levy, Marcel and Lista, Simone and Metzinger, Christiane and Mochel, Fanny and Nyasse, Francis and Poisson, Catherine and Potier, Marie-Claude and Revillon, Marie and Santos, Antonio and Andrade, Katia Santos and Sole, Marine and Surtee, Mohmed and Thiebaut de Schotten, Michel and Vergallo, Andrea and Younsi, Nadjia and Alzheimer Precision Medicine Initiative (APMI) and the INSIGHT-preAD study group and APMI and INSIGHT PreAD Study grp and INSIGHT-preAD study group and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Neurobiology of Aging, ISSN 0197-4580, 11/2019, Volume 83, pp. 42 - 53
Alzheimer's disease (AD) neuropathology is extremely heterogeneous, and the evolution from preclinical to mild cognitive impairment until dementia is driven by... 
Pathophysiology | Precision medicine | Clustering | Alzheimer's disease | Biomarker-guided categorization | CLASSIFICATION | TAU | CEREBROSPINAL-FLUID | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | BLOOD BIOMARKERS | NATIONAL INSTITUTE | DIAGNOSTIC GUIDELINES | NEUROFILAMENT LIGHT | ASSOCIATION WORKGROUPS | Neurosciences | Neurovetenskaper
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2014, Volume 10, Issue 4, pp. P314 - P314
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e49732
The tremendous advances in understanding the neurobiological circuits involved in schizophrenia have not translated into more effective treatments. An... 
SEROTONIN RECEPTOR | PROTEIN | ANTAGONIST | HALOPERIDOL | MULTIDISCIPLINARY SCIENCES | IN-VIVO | D-2 | RISPERIDONE | DOPAMINE-D-2 RECEPTOR-BINDING | OCCUPANCY | ATYPICAL ANTIPSYCHOTICS | Prospective Studies | Humans | Pyrimidinones - therapeutic use | Treatment Outcome | Pyridazines - pharmacology | Neostriatum - drug effects | Piperidines - pharmacology | Antipsychotic Agents - therapeutic use | Piperidines - therapeutic use | Computer Simulation | Pyrimidinones - pharmacology | Antipsychotic Agents - pharmacology | Models, Neurological | Schizophrenia - drug therapy | Pyridazines - therapeutic use | Drugs | Medical research | Olanzapine | Prognosis | Schizophrenia | Diagnostic imaging | Glutamate | Neurophysiology | Liability (Law) | Physiological aspects | Medicine, Experimental | GABA | Models | Drug discovery | Drug therapy | Competition | Neuroleptics | Mental disorders | Circuits | Central nervous system | Clinical trials | Psychotropic drugs | γ-Aminobutyric acid | Metabolites | Rodents | Neostriatum | Tomography | Physiology | Mathematical models | Dopamine D2 receptors | Drug dosages | Genotypes | Dopamine | Medical imaging | Serotonin | Research & development--R&D | Cortex | Positron emission | Pharmacology | Liability | Human pathology | Affinity | Acetylcholine | Norepinephrine | Positron emission tomography | Psychiatry | Research & development | R&D
Journal Article