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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/1993, Volume 90, Issue 14, pp. 6586 - 6590
The maximal T-cell response to its antigen requires presentation of the antigen by a major histocompatibility complex class II molecule as well as the delivery... 
T lymphocytes | Antigens | Molecules | 3T3 cells | Clonal anergy | Secretion | Immune tolerance | Cultured cells | Mice | CHO cells | INTERLEUKIN-2 | HUMAN-LYMPHOCYTES | CD28 PATHWAY | MESSENGER-RNA | GENE | PRESENTING CELLS | MULTIDISCIPLINARY SCIENCES | RECEPTOR | MONOCLONAL-ANTIBODIES | EXPRESSION | ACTIVATION ANTIGEN-B7 | Antigen presenting cells | Analysis | T cell proliferation
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 10/1999, Volume 83, Issue 3, pp. 393 - 400
The identification of tumor‐associated antigens has led to increased interest in vaccination strategies to treat and/or prevent cancer. This study examined the... 
Journal Article
INTERNATIONAL JOURNAL OF CANCER, ISSN 0020-7136, 10/1999, Volume 83, Issue 3, pp. 393 - 400
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/1992, Volume 149, Issue 12, p. 3795
Journal Article
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 07/2001, Volume 8, Issue 7, pp. 687 - 695
Mice transgenic for the rat HER-2/neu oncogene (rNeu-TG) developed spontaneous breast tumors that can escape a rNeu-specific immune response induced by active... 
FasL protein | neu gene | HER2 gene
Journal Article
Cancer Research, ISSN 0008-5472, 01/2002, Volume 62, Issue 2, pp. 437 - 444
HER-2/neu (p185 super(HER2)) oncogene represents an attractive target for antibody-mediated immunotherapy. The major problem of combining chemotherapy and... 
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 09/1991, Volume 174, Issue 3, pp. 625 - 631
Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | CD28 | SIGNALS | SUPERFAMILY | MOLECULAR-CLONING | PROLIFERATION | ACCESSORY CELLS | INDUCTION | IMMUNOLOGY | CLONES | REQUIREMENT
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/1992, Volume 89, Issue 1, pp. 271 - 275
We demonstrate that the murine B7 (mB7) protein is a potent costimulatory molecule for the activation of resting murine CD4+ T cells through the T-cell... 
STIMULATION | LY-6 | MOLECULE | MULTIDISCIPLINARY SCIENCES | DISTINCT | MONOCLONAL-ANTIBODY | INDUCTION | IDENTIFICATION | EXPRESSION | VARIANT | PROTEIN TAP
Journal Article
Nature Medicine, ISSN 1078-8956, 12/1996, Volume 2, Issue 12, pp. 1367 - 1370
Given the plethora of well-documented breast carcinoma-associated antigens in humans including MAGE-1, -2 and -3, mutated p53, p21ras, HER-2/neu and DF3/MUC-1,... 
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 01/1993, Volume 90, Issue 14, pp. 6586 - 6590
The maximal T-cell response to its antigen requires presentation of the antigen by a major histocompatibility complex class II molecule as well as the delivery... 
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 01/1992, Volume 89, Issue 1, pp. 271 - 275
We demonstrate that the murine B7 (mB7) protein is a potent costimulatory molecule for the activation of resting murine CD4 super(+) T cells through the T-cell... 
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 12/1992, Volume 149, Issue 12, pp. 3795 - 3801
Ag-presenting cells provide at least two distinct signals for T cell activation. T cell receptor-dependent stimulation is provided by presentation of a... 
COSTIMULATORY SIGNAL | INTERLEUKIN-2 | IL-2 PRODUCTION | NEOPLASTIC-B-CELLS | GENE | I-ASSOCIATED MYELOPATHY | SUPERFAMILY | MOLECULAR-CLONING | IMMUNOLOGY | ANTIGEN RECEPTOR | LYMPHOCYTES-T
Journal Article
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