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1. Full Text Damage control resuscitation using blood component therapy in standard doses has a limited effect on coagulopathy during trauma hemorrhage
by Khan, Sirat and Khan, Sirat and Davenport, Ross and Davenport, Ross and Raza, Imran and Raza, Imran and Glasgow, Simon and Glasgow, Simon and De’Ath, Henry D and De’Ath, Henry D and Johansson, Pär I and Johansson, Pär I and Curry, Nicola and Curry, Nicola and Stanworth, Simon and Stanworth, Simon and Gaarder, Christine and Gaarder, Christine and Brohi, Karim and Brohi, Karim
Intensive Care Medicine, ISSN 0342-4642, 2/2015, Volume 41, Issue 2, pp. 239 - 247
To determine the effectiveness of blood component therapy in the correction of trauma-induced coagulopathy during hemorrhage.Severe hemorrhage remains a... 
Pediatrics | Plasma | Pain Medicine | Emergency Medicine | Pneumology/Respiratory System | Transfusion | Medicine & Public Health | Intensive / Critical Care Medicine | Anesthesiology | Resuscitation | Damage control | MORTALITY | SURVIVAL | PRODUCTS | RATIO | CRITICAL CARE MEDICINE | Blood Component Transfusion - methods | Prospective Studies | Resuscitation - methods | Hemorrhage - therapy | Wounds and Injuries - blood | Blood Coagulation Disorders - etiology | Humans | Middle Aged | Hemorrhage - complications | Wounds and Injuries - complications | Blood Component Transfusion - adverse effects | Male | Treatment Outcome | Hemorrhage - blood | Blood Coagulation Disorders - therapy | Young Adult | Wounds and Injuries - therapy | Blood Coagulation Disorders - blood | Adult | Female | Cohort Studies | Care and treatment | Blood diseases | Blood transfusion | Patient outcomes
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2. Full Text Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: an international prospective validation study
by Hagemo, Jostein S and Christiaans, Sarah C and Stanworth, Simon J and Brohi, Karim and Johansson, Pär I and Goslings, J. Carel and Naess, Paal A and Gaarder, Christine
Critical care (London, England), ISSN 1364-8535, 2015, Volume 19, Issue 1, pp. 97 - 97
The purpose of this study was to re-evaluate the findings of a smaller cohort study on the functional definition and characteristics of acute traumatic... 
DEFINITION | MORTALITY | CONVENTIONAL COAGULATION TESTS | MANAGEMENT | THERAPY | ADMISSION | HEMORRHAGE | RAPID THROMBELASTOGRAPHY | EARLY PREDICTION | FIBRINOGEN | CRITICAL CARE MEDICINE | Predictive Value of Tests | Prospective Studies | Shock, Hemorrhagic - etiology | Thrombelastography - methods | Blood Coagulation Disorders - etiology | Humans | Middle Aged | Wounds and Injuries - complications | Trauma Centers | Male | Shock, Hemorrhagic - therapy | Blood Transfusion | Time Factors | Hemostasis | Fibrinogen - analysis | Blood Coagulation | Blood Coagulation Disorders - blood | Adult | Female | ROC Curve | Blood Coagulation Disorders - diagnosis | Medicine, Experimental | Medical research | Fibrin | Analysis | Fibrinogen | Viscoelasticity | Ethics | Mortality | Patients | Trauma | Bone surgery | Variance analysis | Research
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3. Full Text Hemostatic resuscitation is neither hemostatic nor resuscitative in trauma hemorrhage
by Khan, Sirat and Brohi, Karim and Chana, Manik and Raza, Imran and Stanworth, Simon and Gaarder, Christine and Davenport, Ross and Int Trauma Res Network INTRN and International Trauma Research Network (INTRN)
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 03/2014, Volume 76, Issue 3, pp. 561 - 568
BACKGROUND Trauma hemorrhage continues to carry a high mortality rate despite changes in modern practice. Traditional approaches to the massively bleeding... 
Plasma | Transfusion | Resuscitation | Damage control | MORTALITY | SURGERY | LACTATE CLEARANCE | BLOOD LACTATE | resuscitation | transfusion | EARLY COAGULOPATHY | plasma | FRESH-FROZEN PLASMA | CRITICAL CARE MEDICINE | Prospective Studies | Thrombelastography | Erythrocyte Transfusion | Exsanguination - complications | Lactic Acid - blood | Blood Coagulation Disorders - etiology | Humans | Middle Aged | Male | Treatment Outcome | Exsanguination - therapy | Hemostatic Techniques | Adult | Female | Exsanguination - blood
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4. Full Text Incidence of chronic pain 6 y after major trauma
by Kolstadbraaten, Knut Magne and Spreng, Ulrich Johannes and Wisloeff‐Aase, Kristin and Gaarder, Christine and Naess, Paal Aksel and Raeder, Johan
Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, 09/2019, Volume 63, Issue 8, pp. 1074 - 1078
Background Life saving measures is the main focus in the initial treatment of major trauma. In surviving patients, chronic pain may be a serious problem, but... 
REGIONAL ANESTHESIA | ANESTHESIOLOGY | MANAGEMENT | PREVALENCE | ANALGESIA | Medical research | Care and treatment | Pain | Analysis | Opioids | Medicine, Experimental | Chronic pain | Drug abuse | Spinal cord | Pain perception | Narcotics | Peripheral nerves | Health risks | Inflammation | Thorax | Spinal cord injury | Risk analysis | Trauma | Patients | Subgroups | Risk factors | Incidence | Analgesia | Analgesics | Surgery | Intubation | Injuries | Injury analysis
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5. Full Text Radiology response in the emergency department during a mass casualty incident: a retrospective study of the two terrorist attacks on 22 July 2011 in Norway
by Young, Victoria Solveig and Eggesbø, Heidi B and Gaarder, Christine and Næss, Pål Aksel and Enden, Tone
European Radiology, ISSN 0938-7994, 07/2017, Volume 27, Issue 7, pp. 2828 - 2834
To describe the use of radiology in the emergency department (ED) in a trauma centre during a mass casualty incident, using a minimum acceptable care (MAC)... 
Mass casualty incident | Emergency radiology | Radiology department | Disaster planning | Trauma | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Emergency Service, Hospital | Humans | Trauma Centers | Male | Wounds, Gunshot - diagnosis | Wounds, Gunshot - epidemiology | Injury Severity Score | Young Adult | Norway - epidemiology | Adolescent | Disaster Planning - methods | Terrorism - statistics & numerical data | Mass Casualty Incidents - statistics & numerical data | Adult | Female | Triage - organization & administration | Retrospective Studies | Radiology | Emergency service | Radiology, Medical | Hospitals | Head injuries | Terrorism | Routines | Head | Films | Shooting | Emergency response | Management | Personnel | Patients | Acceptability | Computed tomography | Imaging | Disaster management | Emergency services | Emergency preparedness | Emergency medical services | Injuries | Emergency Radiology
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6. Full Text Refining the role of splenic angiographic embolization in high-grade splenic injuries
by Skattum, Jorunn and Naess, Paal Aksel and Eken, Torsten and Gaarder, Christine
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 01/2013, Volume 74, Issue 1, pp. 100 - 104
BACKGROUND: The justification and safety of splenic angiographic embolization (SAE) as an adjunct to nonoperative management (NOM) in high-grade splenic... 
high-grade injury | nonoperative management | splenic angiographic embolization | Splenic injury | SURGERY | SPLENECTOMY | ANGIOEMBOLIZATION | COHORT ANALYSIS | CHILDREN | PRESERVATION | IMMUNOLOGICAL FUNCTION | EXPERIENCE | ASSOCIATION | TRAUMA | CRITICAL CARE MEDICINE | Spleen - injuries | Radiography, Interventional | Spleen - diagnostic imaging | Angiography | Humans | Spleen - blood supply | Adult | Embolization, Therapeutic - adverse effects | Injury Severity Score
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7. Full Text The research agenda for trauma critical care
by Asehnoune, Karim and Balogh, Zsolt and Citerio, Giuseppe and Cap, Ane and Billiar, Timothy and Stocchetti, Nino and Cohen, Mitchell J and Pelosi, Paolo and Curry, Nicola and Gaarder, Christine and Gruen, Russell and Holcomb, John and Hunt, Beverley J and Juffermans, Nicole P and Maegele, Mark and Midwinter, Mark and Moore, Frederick A and O'Dwyer, Michael and Pittet, Jean-François and Schöchl, Herbert and Schreiber, Martin and Spinella, Philip C and Stanworth, Simon and Winfield, Robert and Brohi, Karim
Intensive care medicine, ISSN 0342-4642, 2017, Volume 43, Issue 9, pp. 1340 - 1351
In this research agenda on the acute and critical care management of trauma patients, we concentrate on the major factors leading to death, namely haemorrhage... 
Shock | Pediatrics | Emergency Medicine | Traumatic brain injury | Intracranial hypertension | Intensive / Critical Care Medicine | Trauma | Pain Medicine | Pneumology/Respiratory System | Medicine & Public Health | Anesthesiology | Haemorrhage | Coagulopathy | CLINICAL-TRIAL | BRAIN-INJURY | HEMOSTATIC RESUSCITATION | MAJOR HEMORRHAGE | DECOMPRESSIVE CRANIECTOMY | TRANEXAMIC ACID | THERAPY | TRANSFUSION | IMPROVEMENT | CRITICAL CARE MEDICINE | Complications and side effects | Care and treatment | Diagnosis | Research | Wounds and injuries | Neuroimaging | Brain | Coagulation factor VIIa | Coagulation | Clinical trials | Critical care | Neurosurgery | Intracranial pressure | Hemorrhage | Blood | Subgroups | Biological effects | Head injuries | Fibrinogen | Supplementation | Recombinant | Medical research | Patients | Pressure | Hypotension | Fever | Coagulation factors | Augmentation | Magnetic resonance imaging | Perfusion | Predictions | Biomarkers | Skull | Diagnostic systems | Rehabilitation | Avoidance | Hypothermia
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8. Full Text Impact of Trauma System Structure on Injury Outcomes: A Systematic Review and Meta-Analysis
by Moore, Lynne and Moore, Lynne and Champion, Howard and Champion, Howard and Tardif, Pier-Alexandre and Tardif, Pier-Alexandre and Kuimi, Brice-Lionel and Kuimi, Brice-Lionel and O’Reilly, Gerard and O’Reilly, Gerard and Leppaniemi, Ari and Leppaniemi, Ari and Cameron, Peter and Cameron, Peter and Palmer, Cameron S and Palmer, Cameron S and Abu-Zidan, Fikri M and Abu-Zidan, Fikri M and Gabbe, Belinda and Gabbe, Belinda and Gaarder, Christine and Gaarder, Christine and Yanchar, Natalie and Yanchar, Natalie and Stelfox, Henry Thomas and Stelfox, Henry Thomas and Coimbra, Raul and Coimbra, Raul and Kortbeek, John and Kortbeek, John and Noonan, Vanessa K and Noonan, Vanessa K and Gunning, Amy and Gunning, Amy and Gordon, Malcolm and Gordon, Malcolm and Khajanchi, Monty and Khajanchi, Monty and Porgo, Teegwendé V and Porgo, Teegwendé V and Turgeon, Alexis F and Turgeon, Alexis F and Leenen, Luke and Leenen, Luke and Int Injury Care Improvement and International Injury Care Improvement Initiative and On behalf of the International Injury Care Improvement Initiative
World Journal of Surgery, ISSN 0364-2313, 5/2018, Volume 42, Issue 5, pp. 1327 - 1339
The effectiveness of trauma systems in decreasing injury mortality and morbidity has been well demonstrated. However, little is known about which components... 
Medicine & Public Health | Cardiac Surgery | Surgery | Abdominal Surgery | Vascular Surgery | Thoracic Surgery | General Surgery | SURGERY | PHYSICIAN-STAFFED HELICOPTER | LIFE-SUPPORT | RETROSPECTIVE-COHORT | LOW-INCOME | MAJOR TRAUMA | GLOBAL SURGERY | INCLUSIVE TRAUMA | PATIENT OUTCOMES | CENTERS | CARE | Medical personnel | Health care | Websites | Mortality | Systematic review | Trauma | Morbidity | Universal design | Habitability | Reduction | Injury prevention | Reviews | Trauma centers | Qualitative analysis | Transport | Population density | Injury analysis | System effectiveness
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9. Full Text Towards patient-specific management of trauma hemorrhage: the effect of resuscitation therapy on parameters of thromboelastometry
by Juffermans, N. P and Wirtz, M. R and Balvers, K and Baksaas-Aasen, K and van Dieren, S and Gaarder, C and Naess, P. A and Stanworth, S and Johansson, P. I and Stensballe, J and Maegele, M and Goslings, J. C and Brohi, K and Tactic Partners and TACTIC partners and for the TACTIC partners
Journal of thrombosis and haemostasis, ISSN 1538-7933, 2019, Volume 17, Issue 3, pp. 441 - 448
Essentials The response of thromboelastometry (ROTEM) parameters to therapy is unknown. We prospectively recruited hemorrhaging trauma patients in six level-1... 
trauma | transfusion | ROTEM | hemorrhage | viscoelastic hemostatic assay | MORTALITY | INJURY | INDICATOR | HEMOSTATIC RESUSCITATION | PROTHROMBIN TIME | HYPERCOAGULABLE STATE | INDUCED COAGULOPATHY | FIBRINOGEN LEVELS | PERIPHERAL VASCULAR DISEASE | RED-BLOOD-CELLS | HEMATOLOGY | Medical research | Fibrin | Care and treatment | Biological products | Algorithms | Fibrinogen | Medicine, Experimental | Tranexamic acid | Hemorrhage | Geese | Trauma | Bleeding | Clotting | Lysis | COAGULATION | Original
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10. Full Text Defining the optimal cut-off values for liver enzymes in diagnosing blunt liver injury
by Koyama, Tomohide and Hamada, Hirohisa and Nishida, Masamichi and Naess, Paal A and Gaarder, Christine and Sakamoto, Tetsuya
BMC research notes, ISSN 1756-0500, 01/2016, Volume 9, Issue 1, p. 41
Patients with blunt trauma to the liver have elevated levels of liver enzymes within a short time post injury, potentially useful in screening patients for... 
Predictive Value of Tests | Liver - enzymology | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Alanine Transaminase - blood | Biomarkers - blood | Trauma Severity Indices | Liver - injuries | Wounds, Nonpenetrating - diagnostic imaging | Aspartate Aminotransferases - blood | Wounds, Nonpenetrating - diagnosis | Wounds, Nonpenetrating - blood | Liver - diagnostic imaging | Adult | Female | ROC Curve | Retrospective Studies | Wounds, Nonpenetrating - pathology | Measurement | Care and treatment | Liver diseases | Physiological aspects | Alanine aminotransferase | Aspartate aminotransferase | Research | Diagnosis | Studies | Medical imaging | Statistical analysis | Liver | Rodents | Mortality | Patients | Trauma | Medical libraries | Methods | Injuries | Abdomen
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11. Full Text Splenic artery embolisation in children and adolescents—An 8 year experience
by Skattum, Jorunn and Gaarder, Christine and Naess, Paal Aksel
Injury, ISSN 0020-1383, 2012, Volume 45, Issue 1, pp. 160 - 163
Abstract Background Non-operative management (NOM) is the treatment of choice in blunt splenic injuries in the paediatric population, with reported success... 
Orthopedics | Paediatric | Non-operative management | Splenic injury | Splenic artery embolisation | SURGERY | INJURY | COMPUTED-TOMOGRAPHY | ANGIOEMBOLIZATION | PRESERVATION | NONOPERATIVE MANAGEMENT | ANGIOGRAPHIC EMBOLIZATION | EMERGENCY MEDICINE | CONTRAST BLUSH | IMMUNOLOGICAL FUNCTION | PSEUDOANEURYSM | ORTHOPEDICS | TRAUMA | CRITICAL CARE MEDICINE | Splenic Artery - injuries | Spleen - physiopathology | Wounds, Nonpenetrating - complications | Splenic Artery - physiopathology | Humans | Hemorrhage - mortality | Abdominal Injuries - therapy | Male | Treatment Outcome | Hemorrhage - prevention & control | Embolization, Therapeutic | Abdominal Injuries - complications | Injury Severity Score | Spleen - injuries | Wounds, Nonpenetrating - mortality | Abdominal Injuries - mortality | Hemorrhage - etiology | Norway - epidemiology | Wounds, Nonpenetrating - therapy | Adolescent | Female | Registries | Retrospective Studies | Child
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12. Full Text Spleen and liver injuries: When to operate?
by Gaarder, Christine and Gaski, Iver A and Næss, Pål A
Current Opinion in Critical Care, ISSN 1070-5295, 12/2017, Volume 23, Issue 6, pp. 520 - 526
Purpose of reviewAlthough nonoperative management (NOM) is the safest option in most patients with liver and splenic injuries or splenic injuries, some cases... 
liver injuries | nonoperative management | liver packing | splenic injuries | splenectomy | MORTALITY | COAGULOPATHY | ANGIOEMBOLIZATION | HEPATIC-TRAUMA | ORGAN INJURY | TRANSFUSION | BLUNT SPLENIC TRAUMA | COMPLICATIONS | OUTCOMES | CRITICAL CARE MEDICINE | Spleen - physiopathology | Angiography | Risk Assessment | Humans | Abdominal Injuries - surgery | Abdominal Injuries - complications | Evidence-Based Medicine | Liver - physiopathology | Injury Severity Score | Abdominal Injuries - physiopathology | Spleen - injuries | Embolization, Therapeutic - methods | Practice Guidelines as Topic
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13. Full Text Injuries caused by fragmenting rifle ammunition
by Jorgensen, Jorgen Joakim and Naess, Paal Aksel and Gaarder, Christine
Injury, ISSN 0020-1383, 2016, Volume 47, Issue 9, pp. 1951 - 1954
Abstract Introduction Although penetrating injuries are encountered on a regular basis in high volume trauma centres, most civilian trauma teams will be... 
Orthopedics | Fragmenting ammunition | Mass casualty | Gunshot injury | Penetrating injuries | Terrorist attacks | SURGERY | VELOCITY | BALLISTICS | TRAUMA CENTER | CLOSURE | SAFE | SELECTIVE NONOPERATIVE MANAGEMENT | TORSO GUNSHOT WOUNDS | DISCHARGE | EMERGENCY MEDICINE | SHOTGUN WOUNDS | EXPERIENCE | ORTHOPEDICS | CRITICAL CARE MEDICINE | Wounds, Gunshot - surgery | Prospective Studies | Humans | Abdominal Injuries - surgery | Trauma Centers | Wounds, Gunshot - mortality | Male | Abdominal Injuries - diagnostic imaging | Young Adult | Wound Infection - surgery | Female | Mass Casualty Incidents | Fractures, Bone - diagnostic imaging | Craniocerebral Trauma - surgery | Debridement - methods | Terrorism | Wounds, Gunshot - diagnostic imaging | Wound Infection - mortality | Craniocerebral Trauma - diagnostic imaging | Wounds, Penetrating - mortality | Wounds, Penetrating - surgery | Wounds, Penetrating - diagnostic imaging | Fractures, Bone - surgery | Norway | Adolescent | Thoracic Injuries - diagnostic imaging | Rifles | Medical research | Head injuries | Cardiac patients | Medicine, Experimental | Injuries
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14. Ny nasjonal traumeplan
by Wisborg, Torben
Tidsskrift for den Norske Laegeforening, ISSN 0029-2001, 10/2017, Volume 137, Issue 20
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15. Full Text Radiology response in the emergency department during a mass casualty incident: a retrospective study of the two terrorist attacks on 22 July 2011 in Norway
by Young, Victoria Solveig and Eggesbø, Heidi Beate and Gaarder, Christine and Næss, Pål Aksel and Enden, Tone Rønnaug
ISSN 0720-048X, 2017
Objectives: To describe the use of radiology in the emergency department (ED) in a trauma centre during a mass casualty incident, using a minimum acceptable... 
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16. Full Text Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study
by Hagemo, Jostein S and Stanworth, Simon and Juffermans, Nicole P and Brohi, Karim and Cohen, Mitchell and Johansson, Pär I and Røislien, Jo and Eken, Torsten and Næss, Paal A and Gaarder, Christine
Critical care (London, England), ISSN 1364-8535, 2014, Volume 18, Issue 2, pp. R52 - R52
Exsanguination due to trauma-induced coagulopathy is a continuing challenge in emergency trauma care. Fibrinogen is a crucial factor for haemostatic... 
FIBRINOGEN METABOLISM | MORTALITY | ACUTE COAGULOPATHY | MANAGEMENT | ADMISSION | HEMORRHAGE | COAGULATION | MASSIVE TRANSFUSION | INTRAPULMONARY | IDENTIFICATION | CRITICAL CARE MEDICINE | Predictive Value of Tests | Afibrinogenemia - congenital | Prevalence | Prospective Studies | Emergency Treatment - trends | Humans | Middle Aged | Male | Wounds and Injuries - epidemiology | Young Adult | Afibrinogenemia - epidemiology | Wounds and Injuries - therapy | Afibrinogenemia - therapy | Wounds and Injuries - diagnosis | Adult | Female | Retrospective Studies | Afibrinogenemia - diagnosis | Medicine, Experimental | Medical research | Analysis | Research
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