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Immunity, ISSN 1074-7613, 09/2016, Volume 45, Issue 3, pp. 471 - 482
Journal Article
Science, ISSN 0036-8075, 2013, Volume 342, Issue 6163, pp. 1186 - 1186
  Pathogens evolve fast. RNA-based viruses, such as influenza and HIV, incorporate mutations in their genomes at the brisk rate of one change per 105 bases... 
CELLS | CYCLIC REENTRY | MULTIDISCIPLINARY SCIENCES | LIGHT | DYNAMICS | GERMINAL CENTER | BROAD | CENTERS | MATURATION | SPONTANEOUS MUTATION | Pathogens | Immunology | Evolution & development | Immune system | Immune systems | Mutations | Influenza | Bacteria | Viruses | Evolution | Genomes
Journal Article
Science, ISSN 0036-8075, 4/2009, Volume 324, Issue 5925, pp. 392 - 397
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2012, Volume 13, Issue 11, pp. 1083 - 1091
Journal Article
Cell, ISSN 0092-8674, 05/2019, Volume 177, Issue 6, pp. 1370 - 1372
A longitudinal study by Davis et al. followed the evolution of antibody responses in four survivors of the 2014 Ebola outbreak treated in the United States and... 
Viral antibodies | Antibodies | Ebola virus infections
Journal Article
Nature Immunology, ISSN 1529-2908, 04/2014, Volume 15, Issue 4, pp. 313 - 314
Innate lymphoid cells, marginal reticular cells and B cell-helper neutrophils interact to promote antibody secretion by B cells in the marginal zone of the... 
CELLS | MARGINAL ZONE | IMMUNOLOGY | Animals | B-Lymphocytes - immunology | Lymphocytes - immunology | Spleen - immunology | Humans | Antibody Formation | Plasma Cells - immunology | Viral antibodies | Antibodies | Physiological aspects | Physiological research | Research | Immune system
Journal Article
Cold Spring Harbor Perspectives in Biology, 05/2018, Volume 10, Issue 5
Most broadly neutralizing antibodies to HIV-1 have in common an extreme degree of somatic hypermutation (SHM), which correlates with their ability to... 
Antigens | Somatic hypermutation | Immunization | Maturation | Germinal centers | Lymphocytes B | Vaccination | Human immunodeficiency virus--HIV | Antibodies | Affinity | Antibody response
Journal Article
Immunity, ISSN 1074-7613, 06/2017, Volume 46, Issue 6, pp. 1045 - 1058.e6
During antibody affinity maturation, germinal center (GC) B cells cycle between affinity-driven selection in the light zone (LZ) and proliferation and somatic... 
mTOR | B cell | antibody | germinal center | cell cycle | cell size | CENTER B-CELLS | DENDRITIC CELLS | DARK ZONE | GROWTH | C-MYC | TRANSLATION INITIATION | DIFFERENTIATION | IMMUNOLOGY | CELL-CYCLE PROGRESSION | TRANSCRIPTION FACTOR | ONE-STEP GENERATION | Cell Proliferation | Clonal Selection, Antigen-Mediated | Somatic Hypermutation, Immunoglobulin | Cytokines - metabolism | TOR Serine-Threonine Kinases - metabolism | Germinal Center - immunology | Mice, Inbred C57BL | Cells, Cultured | B-Lymphocytes - physiology | Antibody Affinity | Mice, Transgenic | Multiprotein Complexes - genetics | Sirolimus - pharmacology | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Animals | TOR Serine-Threonine Kinases - genetics | Cell Cycle | T-Lymphocytes, Helper-Inducer - immunology | Receptors, Antigen, B-Cell - genetics | Mice | Viral antibodies | Medical colleges | Laws, regulations and rules | Antibodies | B cells | Research institutes | T cells | TOR protein | Enrichment | Cell proliferation | Antigens | Transcription factors | Maturation | Positive selection | Genes | Competitiveness | Cell division | Lymphocytes T | Activation | Rapamycin | Metabolism | Kinases | Somatic hypermutation | Cell growth | Cell activation | Lymphocytes B | Lymphocytes | Cell cycle | Affinity | Clonal selection | Refueling
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2015, Volume 112, Issue 19, p. 6146
  At their margins, tumors often contain neutrophils, dendritic cells, and activated macrophages, which express class II MHC and CD11b products. The interplay... 
Lymphocytes | Rodents | Cells | Tumors
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2015, Volume 112, Issue 19, pp. 6146 - 6151
Journal Article