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1. Full Text What goes up must come down: molecular basis of MAPKAP kinase 2/3-dependent regulation of the inflammatory response and its inhibition
by Gaestel, Matthias
Biological chemistry, ISSN 1431-6730, 10/2013, Volume 394, Issue 10, pp. 1301 - 1315
mitogen-activated protein kinase-activated protein kinase (MAPKAP) | protein kinase inhibitor | protein phosphorylation | mitogen-activated protein kinase-activated protein kinases 2/3 (MK2/3) | Mitogen-activated protein kinase-activated protein kinase (MAPKAP) | Mitogen-activated protein kinase-activated protein kinases 2/3 (MK2/3) | Protein kinase inhibitor | Protein phosphorylation | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Gene Expression Regulation - drug effects | Animals | Humans | Imidazoles - pharmacology | Inflammation | Intracellular Signaling Peptides and Proteins - metabolism | Pyridines - pharmacology | Immunity, Innate | Protein-Serine-Threonine Kinases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Physiological aspects | Research | Molecular biology | Health aspects | Mitogen-activated protein kinases | Index Medicus
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2. Full Text Targeting innate immunity protein kinase signalling in inflammation
by Gaestel, Matthias and Kracht, Michael and Kotlyarov, Alexey
Nature reviews. Drug discovery, ISSN 1474-1776, 06/2009, Volume 8, Issue 6, pp. 480 - 499
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Protein Kinases - metabolism | Inflammation Mediators - administration & dosage | Immunity, Innate - drug effects | Humans | Inflammation Mediators - therapeutic use | Inflammation - immunology | Protein Kinase Inhibitors - administration & dosage | Signal Transduction - immunology | Animals | Protein Kinases - immunology | Signal Transduction - drug effects | Inflammation - drug therapy | Protein Kinase Inhibitors - therapeutic use | Drug Delivery Systems - trends | Drug Delivery Systems - methods | Inflammation - enzymology | Inflammation | Dosage and administration | Research | Nonsteroidal anti-inflammatory drugs | Drug therapy | Protein kinases | Immunity | Health aspects | Index Medicus
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3. Full Text MAPKAP kinases — MKs — two's company, three's a crowd
by Gaestel, Matthias
Nature reviews. Molecular cell biology, ISSN 1471-0072, 02/2006, Volume 7, Issue 2, pp. 120 - 130
Life Sciences & Biomedicine | Science & Technology | Cell Biology | 14-3-3 Proteins - metabolism | Mitogen-Activated Protein Kinase Kinases - chemistry | Mitogen-Activated Protein Kinase Kinases - metabolism | Mitogen-Activated Protein Kinase Kinases - genetics | Phosphorylation | Animals | Inflammation - genetics | Protein Conformation | Transcription, Genetic | Mice | Amino Acid Motifs | Index Medicus
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4. Full Text MAPK-Activated Protein Kinases (MKs): Novel Insights and Challenges
by Gaestel, Matthias
Frontiers in cell and developmental biology, ISSN 2296-634X, 01/2016, Volume 3, pp. 88 - 88
Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Tumor suppressor genes | Cellular signal transduction | Research | Protein kinases | Extracellular signal-regulated kinases | common docking motif | Dendritic Cells | macrophage-specific activation | p38 MAPK | Ras-induced senescence | ERK3/4
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5. Full Text MK2–TNF–Signaling Comes Full Circle
by Menon, Manoj B and Gaestel, Matthias
Trends in biochemical sciences (Amsterdam. Regular ed.), ISSN 0968-0004, 03/2018, Volume 43, Issue 3, pp. 170 - 179
apoptosis | TNF signaling | TNF receptor | protein phosphorylation | protein kinase | necroptosis | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Tumor necrosis factor | Index Medicus
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