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Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 01/2018, Volume 33, Issue 1, pp. S5 - S5
Journal Article
Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie, ISSN 0044-409X, 07/2019
Zusammenfassung Hintergrund Die hypertherme intrathorakale Chemotherapie (HITOC) wird bereits seit einigen Jahren in mehreren thoraxchirurgischen Kliniken... 
Sonstige
Journal Article
The Annals of Thoracic Surgery, ISSN 0003-4975, 09/2019, Volume 108, Issue 3, pp. 960 - 961
Journal Article
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, ISSN 1742-7835, 08/2017, Volume 121, pp. 5 - 5
Conference Proceeding
Pharmaceutical Research, ISSN 0724-8741, 3/2013, Volume 30, Issue 3, pp. 761 - 780
To apply physiologically-based pharmacokinetic (PBPK) modeling to investigate the consequences of reduction in activity of hepatic and intestinal uptake and... 
Biochemistry, general | Biomedical Engineering | cyclosporine | drug-drug interactions | Biomedicine | Pharmacy | OATP1B3 | Medical Law | Pharmacology/Toxicology | physiologically-based pharmacokinetic models | OATP1B1 | ERYTHROCYTE BINDING | IN-VITRO CLEARANCE | SLCO1B1 POLYMORPHISM | REPAGLINIDE PHARMACOKINETICS | MARROW TRANSPLANT PATIENTS | CHEMISTRY, MULTIDISCIPLINARY | MICROEMULSION FORMULATION | 1ST-PASS METABOLISM | PHYSIOLOGICALLY-BASED PHARMACOKINETICS | HEALTHY MALE-VOLUNTEERS | GRAPEFRUIT JUICE | PHARMACOLOGY & PHARMACY | Intestines - drug effects | Intestinal Mucosa - metabolism | Organic Anion Transporters - antagonists & inhibitors | Organic Anion Transporters, Sodium-Independent - antagonists & inhibitors | Enzyme Inhibitors - metabolism | Cyclosporine - pharmacology | Humans | Liver - metabolism | Enzyme Inhibitors - pharmacology | Organic Anion Transporters - metabolism | Cytochrome P-450 CYP3A Inhibitors | Drug Interactions | Enzyme Inhibitors - pharmacokinetics | Liver - drug effects | Cytochrome P-450 CYP3A - metabolism | Models, Biological | Organic Anion Transporters, Sodium-Independent - metabolism | HEK293 Cells | Cyclosporine - pharmacokinetics | Liver-Specific Organic Anion Transporter 1 | Cyclosporine - metabolism | Solute Carrier Organic Anion Transporter Family Member 1B3 | Complications and side effects | Metabolites | Drug interactions | Cytochrome P-450 | Drugstores | Models | Physicians (General practice) | Cyclosporine | Side effects | Pharmacology | Kinetics
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 10/2011, Volume 39, Issue 10, pp. 1808 - 1814
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 09/2011, Volume 39, Issue 9, pp. 1633 - 1642
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 9/2014, Volume 31, Issue 9, pp. 2367 - 2382
Journal Article
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 6/2015, Volume 32, Issue 6, pp. 1864 - 1883
To develop a population physiologically-based pharmacokinetic (PBPK) model for simvastatin (SV) and its active metabolite, simvastatin acid (SVA), that allows... 
Biochemistry, general | Biomedical Engineering | drug-drug interactions | Biomedicine | Pharmacy | PBPK | simvastatin | Medical Law | population model | Pharmacology/Toxicology | OATP1B1 | HYDROXY ACID | VARIANTS | DRUG-INTERACTIONS | "simvastatin" | QUANTIFICATION | IN-VITRO DATA | "population model" | "OATP1B1" | STATINS | CHEMISTRY, MULTIDISCIPLINARY | DISPOSITION | PRIOR DISTRIBUTIONS | "PBPK" | PHARMACOLOGY & PHARMACY | "drug-drug interactions" | PRAVASTATIN | INHIBITORS | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Activation, Metabolic | Cytochrome P-450 Enzyme Inhibitors - therapeutic use | Simvastatin - adverse effects | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood | Biological Availability | Muscle, Skeletal - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - chemistry | Healthy Volunteers | Simvastatin - blood | Organic Anion Transporters - metabolism | Tissue Distribution | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Organic Anion Transporters - genetics | Drug Interactions | Liver - drug effects | Muscle, Skeletal - drug effects | Muscular Diseases - chemically induced | Pharmacogenetics | Reproducibility of Results | Simvastatin - chemistry | Muscular Diseases - metabolism | Simvastatin - administration & dosage | Liver - metabolism | Simvastatin - pharmacokinetics | Simvastatin - analogs & derivatives | Polymorphism, Genetic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Models, Biological | Solute Carrier Organic Anion Transporter Family Member 1b1 | Metabolites | Simvastatin | Drug interactions | Liver | Cytochrome P-450 | Antilipemic agents | Side effects | Pharmacology | Kinetics | Statins | Index Medicus
Journal Article