Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (323) 323
Book Review (27) 27
Publication (25) 25
Patent (15) 15
Book Chapter (12) 12
Conference Proceeding (11) 11
Web Resource (2) 2
Dissertation (1) 1
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (161) 161
animals (144) 144
calcium - metabolism (113) 113
biochemistry & molecular biology (87) 87
cyclic adp-ribose (86) 86
nadp - analogs & derivatives (81) 81
calcium (75) 75
inositol trisphosphate (60) 60
naadp (56) 56
sea-urchin eggs (53) 53
adenine-dinucleotide phosphate (52) 52
nadp - metabolism (52) 52
humans (46) 46
calcium channels - metabolism (43) 43
sea urchins (42) 42
cell biology (41) 41
male (35) 35
adenosine diphosphate ribose - analogs & derivatives (33) 33
mice (33) 33
ryanodine receptor (33) 33
calcium signaling (31) 31
signal transduction (30) 30
female (29) 29
fertilization (28) 28
calcium signaling - physiology (27) 27
calcium-release (27) 27
cells (27) 27
nadp - pharmacology (27) 27
ovum - metabolism (27) 27
calcium signaling - drug effects (25) 25
calcium channels - genetics (24) 24
lysosomes - metabolism (24) 24
ca2+ release (23) 23
rats (23) 23
cyclic-adp-ribose (21) 21
biophysics (20) 20
cells, cultured (20) 20
activation (19) 19
endoplasmic-reticulum (19) 19
release (19) 19
research (19) 19
stores (19) 19
hydrogen-ion concentration (18) 18
in vitro techniques (18) 18
adenosine diphosphate ribose - pharmacology (17) 17
beta-cells (17) 17
ca2 (17) 17
induced ca2+ release (17) 17
receptors (17) 17
2-pore channels (16) 16
article (16) 16
lysosomes (16) 16
physiological aspects (16) 16
chemistry (15) 15
ovum - drug effects (15) 15
adp-ribosyl cyclase (14) 14
kinetics (14) 14
nicotinic acid adenine dinucleotide phosphate (14) 14
pancreatic-acinar-cells (14) 14
binding (13) 13
biology (13) 13
human necessities (13) 13
hygiene (13) 13
inactivation (13) 13
medical or veterinary science (13) 13
mice, knockout (13) 13
multidisciplinary sciences (13) 13
preparations for medical, dental, or toilet purposes (13) 13
ryanodine receptor calcium release channel - metabolism (13) 13
ryanodine receptors (13) 13
adenosine diphosphate ribose - metabolism (12) 12
cd38 (12) 12
cell line (12) 12
endoplasmic reticulum (12) 12
enzyme inhibitors - pharmacology (12) 12
induced calcium-release (12) 12
inositol 1,4,5-trisphosphate - metabolism (12) 12
ryanodine - pharmacology (12) 12
calcium channels (11) 11
endosomes - metabolism (11) 11
guinea pigs (11) 11
inositol 1,4,5-trisphosphate - pharmacology (11) 11
inositol 1,4,5-trisphosphate receptors (11) 11
life sciences (11) 11
lysosome (11) 11
metallurgy (11) 11
mobilizes ca2 (11) 11
models, biological (11) 11
nadp - chemistry (11) 11
nadp - physiology (11) 11
organic chemistry (11) 11
second messenger systems (11) 11
adenosine diphosphate ribose - physiology (10) 10
biochemistry (10) 10
calcium channels - physiology (10) 10
endoplasmic reticulum - metabolism (10) 10
general tagging of cross-sectional technologies spanning over several sections of the ipc (10) 10
general tagging of new technological developments (10) 10
microsomes (10) 10
molecular biology (10) 10
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. NAADP Receptors
by Galione, Antony
Cold Spring Harbor perspectives in biology, 06/2019
Of the established Ca -mobilizing messengers, NAADP is arguably the most tantalizing. It is the most potent, often efficacious at low nanomolar concentrations,... 
Journal Article
Details down arrow
2. Full Text A primer of NAADP-mediated Ca2+ signalling: From sea urchin eggs to mammalian cells
by Galione, Antony
Cell Calcium, ISSN 0143-4160, 2014, Volume 58, Issue 1, pp. 27 - 47
Graphical abstract 
Advanced Basic Science | Two-pore channel | NAADP | Calcium | Lysosome | Organelle | Intracellular | Messenger | ADENINE-DINUCLEOTIDE PHOSPHATE | FROG NEUROMUSCULAR-JUNCTION | LYSOSOMAL CALCIUM HOMEOSTASIS | CELL BIOLOGY | SMOOTH-MUSCLE | CYCLIC-ADP-RIBOSE | RYANODINE RECEPTOR | PANCREATIC BETA-CELLS | INOSITOL TRISPHOSPHATE | 2-PORE CHANNEL 2 | CORONARY ARTERIAL MYOCYTES
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. cADPR and NAADP
: messengers for calcium signalling
by Galione, Antony
2007, Calcium signaling I : regulation, mechanisms, effectors, role in disease and recent advances
analogs & derivatives | Cyclic ADP-Ribose | NADP | Calcium Signaling
Web Resource
Details down arrow
4. cADPR and NAADP
: messengers for calcium signalling
by Galione, Antony
2007, Calcium signaling : regulation, mechanisms, effectors, role in disease and recent advances
analogs & derivatives | Cyclic ADP-Ribose | NADP | Calcium Signaling
Web Resource
Details down arrow
5. Full Text A primer of NAADP-mediated Ca.sup.2+ signalling: From sea urchin eggs to mammalian cells
by Galione, Antony
Cell Calcium, ISSN 0143-4160, 07/2015, Volume 58, Issue 1, p. 27
Cells | Eggs
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Two‐pore channels (TPCs): Current controversies
by Morgan, Anthony J and Galione, Antony
BioEssays, ISSN 0265-9247, 02/2014, Volume 36, Issue 2, pp. 173 - 183
The second messenger, NAADP, stimulates Ca 2+ release from acidic (endo‐lysosomal) Ca 2+ stores, and the Ca 2+ channels opened by NAADP were thought to be... 
channel | NAADP | lysosome | TPC | Ca | Channel | Lysosome | CYCLIC ADP-RIBOSE | POTASSIUM CHANNELS | ADENINE-DINUCLEOTIDE PHOSPHATE | CA2+ RELEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REGULATES AUTOPHAGY | ACIDIC ORGANELLES | Ca2 | CALCIUM-RELEASE | BIOLOGY | INOSITOL TRISPHOSPHATE | SEA-URCHIN EGG | ION CHANNELS | Animals | Lysosomes - metabolism | Calcium Channels - metabolism | Calcium - metabolism | Humans | NADP - analogs & derivatives | NADP - metabolism | Lysosomes | Calcium channels | Research | Medical treatment | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text VEGF-induced neoangiogenesis is mediated by NAADP and two-pore channel-2–dependent Ca2+ signaling
by Annarita Favia and Marianna Desideri and Guido Gambara and Alessio D’Alessio and Margarida Ruas and Bianca Esposito and Donatella Del Bufalo and John Parrington and Elio Ziparo and Fioretta Palombi and Antony Galione and Antonio Filippini
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 11/2014, Volume 111, Issue 44, pp. E4706 - 4715
Vascular endothelial growth factor (VEGF) and its receptors VEGFR1/VEGFR2 play major roles in controlling angiogenesis, including vascularization of solid... 
Calcium signaling | Antiangiogenic strategies | Naadp receptors | TPC2 | Endothelial cells | endothelial cells | ENDOTHELIAL-CELL PROLIFERATION | ADENINE-DINUCLEOTIDE PHOSPHATE | MULTIDISCIPLINARY SCIENCES | calcium signaling | BETA-CELLS | NAADP receptors | RECEPTOR | TUMOR ANGIOGENESIS | CROSS-TALK | IN-VITRO | CALCIUM | antiangiogenic strategies | GROWTH-FACTOR | MOLECULAR-MECHANISMS | Neovascularization, Physiologic - drug effects | Calcium Channels - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Calcium Signaling - physiology | Humans | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | NADP - antagonists & inhibitors | Piperazines - pharmacology | Mice, Knockout | Vascular Endothelial Growth Factor Receptor-2 - genetics | Neovascularization, Physiologic - physiology | Animals | Calcium Signaling - drug effects | Human Umbilical Vein Endothelial Cells - cytology | NADP - analogs & derivatives | Mice | NADP - metabolism | NADP - genetics | Calcium Channels - genetics | Carbolines - pharmacology | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Cytokines: Revealing the secrets of secretion
by Galione, Antony and Galione, Antony and Davis, Lianne C
eLife, 11/2018, Volume 7
cytokine | mouse | TRPML2 | endosome | secretion | chemical biology | biochemistry | CCL2 | macrophage
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation
by Shigeto, Makoto and Ramracheya, Reshma and Tarasov, Andrei I and Cha, Chae Young and Chibalina, Margarita V and Hastoy, Benoit and Philippaert, Koenraad and Reinbothe, Thomas and Rorsman, Nils and Salehi, Albert and Sones, William R and Vergari, Elisa and Weston, Cathryn and Gorelik, Julia and Katsura, Masashi and Nikolaev, Viacheslav O and Vennekens, Rudi and Zaccolo, Manuela and Galione, Antony and Johnson, Paul R.V and Kaku, Kohei and Ladds, Graham and Rorsman, Patrik and Institute of Neuroscience and Physiology and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Physiology and Sahlgrenska Academy and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi and Institutionen för neurovetenskap och fysiologi
Journal of Clinical Investigation, ISSN 0021-9738, 12/2015, Volume 125, Issue 12, pp. 4714 - 4728
Strategies aimed at mimicking or enhancing the action of the incretin hormone glucagon-like peptide 1 (GLP-1) therapeutically improve glucose-stimulated... 
ACTION-POTENTIALS | SIGNAL | MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN-KINASE-C | GLUCAGON-LIKE PEPTIDE-1 | GLUCOSE | CALCIUM | PANCREATIC BETA-CELLS | RECEPTOR | RAT ISLETS | MOUSE ISLETS | Membrane Potentials - drug effects | Protein Kinase C - genetics | Membrane Potentials - genetics | Tetradecanoylphorbol Acetate - pharmacology | Humans | Glucagon-Like Peptide 1 - pharmacology | Mice, Knockout | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Protein Kinase C - metabolism | TRPM Cation Channels - genetics | Ion Transport - drug effects | Insulin-Secreting Cells - cytology | Mice | TRPM Cation Channels - metabolism | Insulin - genetics | Insulin Secretion | Ion Transport - genetics | Physiological aspects | Pancreatic beta cells | Gastrointestinal hormones | Properties | Insulin | Ethics | Medical research | Biomedical research | Councils | Rodents | Physiology | Glucose | Diabetes | Pancreas | Experiments | Index Medicus | Abridged Index Medicus | Fysiologi | DIABETIC-PATIENTS | B-CELLS | CATION CHANNEL TRPM4 | TYPE-2
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Revealing the secrets of secretion
by Galione, A and Davis, LC
ELIFE, ISSN 2050-084X, 11/2018, Volume 7
An intracellular ion channel may have a central role in the release of cytokines by macrophages. 
TRPML2 | BIOLOGY | Cytokines | Macrophages | Chemokines | Physiological aspects | Research | Secretion | Immunological research | Proteins | Endoplasmic reticulum | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Molecular mechanisms of endolysosomal Ca 2+ signalling in health and disease
by Morgan, Anthony J and Platt, Frances M and Lloyd-Evans, Emyr and Galione, Antony
Biochemical Journal, ISSN 0264-6021, 11/2011, Volume 439, Issue 3, pp. 349 - 374
Calcium store | Endolysosome | Nicotinic acid adenine dinucleotide phosphate (NAADP) | ATPase | Two-pore channel (TPC)
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
by Sillence, Daniel J and Morgan, Anthony J and Smith, David A and Churchill, Grant C and Galione, Antony and Platt, Frances M and Schuchman, Edward H and Elliot-Smith, Elena and Lloyd-Evans, Emyr and He, Xingxuan
Nature Medicine, ISSN 1078-8956, 11/2008, Volume 14, Issue 11, pp. 1247 - 1255
Niemann-Pick type C1 (NPC1) disease is a neurodegenerative lysosomal storage disorder caused by mutations in the acidic compartment (which we define as the... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | NPC1 PROTEIN | CHOLESTEROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | CERAMIDE | CELL BIOLOGY | INTRACELLULAR CA2 | METABOLISM | STORES | MICE | BINDING | Niemann-Pick Disease, Type C - drug therapy | Membrane Glycoproteins - metabolism | Calcium - metabolism | Humans | Homeostasis | Niemann-Pick Disease, Type C - classification | Niemann-Pick Disease, Type C - metabolism | Lysosomes - metabolism | Sphingosine - metabolism | Cell Line | Curcumin - therapeutic use | Cholesterol - metabolism | Mutation - genetics | Membrane Glycoproteins - genetics | Mice, Knockout | Proteins - genetics | Carrier Proteins - genetics | Phenotype | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Acids | Glycosphingolipids - metabolism | Mice | Niemann-Pick Disease, Type C - genetics | Niemann-Pick disease | Care and treatment | Gene mutations | Calcium metabolism disorders | Causes of | Genetic aspects | Research | Health aspects | Risk factors | Genotype & phenotype | Pathology | Mutation | Cellular biology | Neurological disorders | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text NAADP mobilizes calcium from acidic organelles through two-pore channels
by Chuang, Kai-Ting and Lin, Peihui and Wyatt, Christopher N and Lin, Yakang and Zhu, Michael X and Tang, Jisen and Teboul, Lydia and Zhu, Yingmin and Evans, A. Mark and Ma, Jianjie and Pan, Zui and Calcraft, Peter J and Cheng, Xiaotong and Wang, Chunbo and Xiao, Rui and Parrington, John and Galione, Antony and Rietdorf, Katja and Arredouani, Abdelilah and Hao, Xuemei and Ruas, Margarida
Nature, ISSN 0028-0836, 05/2009, Volume 459, Issue 7246, pp. 596 - 600
Ca2+ mobilization from intracellular stores represents an important cell signalling process that is regulated, in mammalian cells, by... 
HEART | CYCLIC ADP-RIBOSE | MECHANISM | STORES | ADENINE-DINUCLEOTIDE PHOSPHATE | CA2+ RELEASE | RYANODINE RECEPTORS | MULTIDISCIPLINARY SCIENCES | PANCREATIC BETA-CELLS | INOSITOL TRISPHOSPHATE | MESSENGER | Cell Line | Calcium Channels - metabolism | Calcium - metabolism | Humans | Molecular Sequence Data | Organelles - drug effects | NADP - pharmacology | Mice, Knockout | Insulin-Secreting Cells - metabolism | Animals | Insulin-Secreting Cells - drug effects | Calcium Signaling - drug effects | Chickens | NADP - analogs & derivatives | Protein Binding | Mice | NADP - metabolism | Calcium Channels - genetics | Organelles - metabolism | Hydrogen-Ion Concentration | Calcium, Dietary | NADP (Coenzyme) | Cellular control mechanisms | Ion channels | Cell organelles | Chemical properties | Research | Properties | Calcium | Molecular biology | Cells | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Two-pore channels (TPCs): Current controversies
: Prospects & Overviews
by Morgan, Anthony J and Galione, Antony
BioEssays, ISSN 0265-9247, 02/2014, Volume 36, Issue 2, pp. 173 - 183
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Fertilization and Nicotinic Acid Adenine Dinucleotide Phosphate Induce pH Changes in Acidic Ca2+ Stores in Sea Urchin Eggs
by Anthony J. Morgan and Antony Galione
Journal of Biological Chemistry, ISSN 0021-9258, 12/2007, Volume 282, Issue 52, pp. 37730 - 37737
The second messenger nicotinic acid adenine dinucleotide phosphate (NAADP) releases Ca 2+ from the acidic Ca 2+ stores of many organisms, including those of... 
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Reply to “TPC1 Knockout Knocks Out TPC1”
by Ruas, Margarida and Galione, Antony and Parrington, John
Molecular and Cellular Biology, ISSN 0270-7306, 05/2015, Volume 35, Issue 10, pp. 1884 - 1884
Letters to the Editor
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text Identification of a chemical probe for NAADP by virtual screening
by Naylor, Edmund and Rosen, Daniel and Vasudevan, Sridhar R and Thomas, Justyn M and Ganesan, A and Churchill, Grant C and Galione, Antony and Parkesh, Raman and Arredouani, Abdelilah and Lewis, Alexander M and Izumi, Minoru and Mizote, Akiko
Nature Chemical Biology, ISSN 1552-4450, 04/2009, Volume 5, Issue 4, pp. 220 - 226
Research into the biological role of the Ca2+-releasing second messenger NAADP (nicotinic acid adenine dinucleotide phosphate) has been hampered by a lack of... 
CYCLIC ADP-RIBOSE | SHAPE | CALCIUM-MOBILIZING ACTIVITY | ADENINE-DINUCLEOTIDE PHOSPHATE | CA2+ RELEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | INSULIN-SECRETION | PANCREATIC BETA-CELLS | RECEPTOR | ENDOPLASMIC-RETICULUM | Models, Molecular | Inositol 1,4,5-Trisphosphate - pharmacology | Piperazines - chemistry | Sea Urchins | NADP - chemistry | Piperazines - pharmacology | Cyclic ADP-Ribose - pharmacology | Carbolines - chemistry | Animals | Insulin-Secreting Cells - drug effects | Small Molecule Libraries | NADP - analogs & derivatives | Ovum - chemistry | Mice | Molecular Structure | NADP - metabolism | Carbolines - pharmacology | Signal transduction | Biochemistry | Molecular biology | Chemical compounds | Research methodology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights