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1. Full Text Proteomic screening for amyloid proteins
by Nizhnikov, Anton A and Alexandrov, Alexander I and Ryzhova, Tatyana A and Mitkevich, Olga V and Dergalev, Alexander A and Ter-Avanesyan, Michael D and Galkin, Alexey P
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e116003
Despite extensive study, progress in elucidation of biological functions of amyloids and their role in pathology is largely restrained due to the lack of... 
EXPANDED POLYGLUTAMINE | PSI+ PRION | MULTIDISCIPLINARY SCIENCES | Q/N-RICH | PURIFICATION | SUP35 | HUNTINGTIN FRAGMENT | SACCHAROMYCES-CEREVISIAE | TRANSCRIPTION FACTOR | YEAST PRION | CELLULAR TOXICITY | Detergents - pharmacology | Humans | Electrophoresis, Gel, Two-Dimensional | Amyloidogenic Proteins - isolation & purification | Nerve Tissue Proteins - metabolism | Huntingtin Protein | Amyloidogenic Proteins - metabolism | Animals | Sarcosine - analogs & derivatives | Proteomics - methods | Fungal Proteins - isolation & purification | Mass Spectrometry - methods | Sarcosine - pharmacology | Biotechnology | Yeast | Huntingtin | Identification methods | Sperm | Identification | Biochemistry | Ultracentrifugation | Seeding | Proteins | Spectrometry | Genetics | Electrophoresis | Prion protein | Trinucleotide repeat diseases | Polyglutamine | Gel electrophoresis | Polymerization | Forming | Mammals | Gene expression | Detergents | Medical screening | Sedimentation | Screening | Aggregates | Prions | Asparagine | Glutamine
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2. Full Text Mechanism of mitochondrial complex I damage in brain ischemia/reperfusion injury. A hypothesis
by Ten, Vadim and Galkin, Alexander
Molecular and Cellular Neuroscience, ISSN 1044-7431, 10/2019, Volume 100, p. 103408
The purpose of this review is to integrate available data on the effect of brain ischemia/reperfusion (I/R) on mitochondrial complex I. Complex I is a key... 
Riboflavin | Stroke | Ischemia-reperfusion injury | Mitochondria | Complex I | Flavin
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3. Full Text Characterisation of the active/de-active transition of mitochondrial complex I
by Galkin, Alexander
BBA - Bioenergetics, ISSN 0005-2728, 07/2014, Volume 1837, pp. e39 - e39
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4. Full Text Methane as an Organic Matter Source and the Trophic Basis of a Laptev Sea Cold Seep Microbial Community
by Savvichev, Alexander S and Kadnikov, Vitaliy V and Kravchishina, Marina D and Galkin, Sergey V and Novigatskii, Alexander N and Sigalevich, Pavel A and Merkel, Alexander Yu and Ravin, Nikolai V and Pimenov, Nikolai V and Flint, Mikhail V
Geomicrobiology Journal, ISSN 0149-0451, 05/2018, Volume 35, Issue 5, pp. 411 - 423
An area of cold methane seeps at the bottom of the Laptev Sea was investigated. High rates of methane oxidation were revealed in the sediments and in the water... 
Cold methane seep | microbial community | Arctic seas | rates of microbial processes | anaerobic oxidation of methane | SULFIDE-OXIDIZING BACTERIA | WATER COLUMN | MICROBIOLOGICAL PROCESSES | ENVIRONMENTAL SCIENCES | GEOSCIENCES, MULTIDISCIPLINARY | MOSBY MUD VOLCANO | SURFACE SEDIMENTS | SULFUR CYCLES | DIVERSITY | ANAEROBIC METHANOTROPHS | CHUKCHI SEA | SPATIAL-DISTRIBUTION | Seepage | Methane | Sulfate reduction | Organic matter | Methanotrophic bacteria | Water column | Agents | Sulfur cycle | Sediments | Sulphur | Sulphate reduction | Consortia | Bioturbation | Microorganisms | Reduction | Bacteria | Seepages | Oxidation | Sulfur | Bottom water
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5. Full Text Characterization of the effectors of ischemic conformational changes of mitochondrial complex I
by Stepanova, Anna and Galkin, Alexander
BBA - Bioenergetics, ISSN 0005-2728, 08/2016, Volume 1857, pp. e80 - e80
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6. Mitochondrial biogenesis and breakdown
by Luzikov, Valentin N and Roodyn, Donald B and Consultants Bureau and Consultants Bureau Enterprises
1985, ISBN 0306109794, xvi, 362
Mitochondria
Book
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7. Full Text Optimization flow model for handling car flows at the marshalling yard
by Alexandrov, Alexander and Galkin, Alexander and Timukhina, Elena and Tushin, Nikolai
MATEC Web of Conferences, ISSN 2261-236X, 10/2018, Volume 216, p. 2024
Mathematical modeling is widely used in studies of operational planning in railway transport. Mainly heuristic algorithms and simulation modeling is used in... 
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8. Full Text Chronic respiratory diseases and risk factors in 12 regions of the Russian Federation
by Chuchalin, Alexander G and Khaltaev, Nikolai and Antonov, Nikolay S and Galkin, Dmitry V and Manakov, Leonid G and Antonini, Paola and Murphy, Michael and Solodovnikov, Alexander G and Bousquet, Jean and Pereira, Marcelo H.S and Demko, Irina V
International Journal of COPD, ISSN 1176-9106, 09/2014, Volume 9, pp. 963 - 974
Background: Estimation suggests that at least 4 million people die, annually, as a result of chronic respiratory disease (CRD). The Global Alliance against... 
Prevalence | Chronic respiratory diseases | GARD | Russia | CHRONIC-BRONCHITIS | ALLERGIC RHINITIS | chronic respiratory diseases | RANDOMIZED CONTROLLED-TRIAL | prevalence | OBSTRUCTIVE PULMONARY-DISEASE | OPTIMAL ASTHMA CONTROL | PRIMARY-CARE | RESPIRATORY SYSTEM | NORTHERN SWEDEN | LUNG-DISEASE | LATIN-AMERICAN CITIES | COPD | Spirometry | Bronchitis, Chronic - epidemiology | Humans | Middle Aged | Male | Bronchitis, Chronic - diagnosis | Pulmonary Disease, Chronic Obstructive - physiopathology | Rhinitis, Allergic - physiopathology | Pulmonary Disease, Chronic Obstructive - epidemiology | Rhinitis, Allergic - diagnosis | Forced Expiratory Volume | Young Adult | Aged, 80 and over | Adult | Female | Surveys and Questionnaires | Russia - epidemiology | Pulmonary Disease, Chronic Obstructive - diagnosis | Cross-Sectional Studies | Risk Factors | Lung - physiopathology | Bronchitis, Chronic - physiopathology | Rhinitis, Allergic - epidemiology | Vital Capacity | Health Surveys | Aged | Respiratory tract diseases | Research | Diagnosis | Public health | Risk factors
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9. Applying full-azimuth depth imaging in the local angle domain to delineate hard-to-recover hydrocarbon reserves
by Inozemtsev, Alexander and Koren, Zvi and Galkin, Alexander
First Break, ISSN 0263-5046, 12/2017, Volume 35, Issue 12, pp. 49 - 58
Journal Article
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10. Full Text S-Nitrosation of Mitochondrial Complex I Depends on Its Structural Conformation
by Alexander Galkin and Salvador Moncada
Journal of Biological Chemistry, ISSN 0021-9258, 12/2007, Volume 282, Issue 52, pp. 37448 - 37453
Nitric oxide is known to cause persistent inhibition of mitochondrial respiration as a result of S -nitrosation of NADH: ubiquinone oxidoreductase (complex I)... 
PERSISTENT INHIBITION | NADH-UBIQUINONE REDUCTASE | OXYGEN-CONSUMPTION | CATALYTIC-PROPERTIES | PEROXYNITRITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELAXING FACTOR | NITRIC-OXIDE | ACTIVE/DE-ACTIVE TRANSITION | RAT-HEART | ELECTRON-TRANSPORT | Mitochondria, Heart - metabolism | Nitric Oxide - chemistry | Oxidative Stress | Molecular Conformation | Superoxides - chemistry | Electron Transport Complex I - metabolism | Multienzyme Complexes - chemistry | NAD - chemistry | Animals | Time Factors | Cattle | Models, Biological | Myocardium - metabolism | Hypoxia | NADH, NADPH Oxidoreductases - chemistry | Sulfhydryl Compounds - chemistry | Peroxynitrous Acid - chemistry
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11. Full Text Development and validation of a CAE chain for unidirectional fibre reinforced composite components
by Kärger, Luise and Bernath, Alexander and Fritz, Florian and Galkin, Siegfried and Magagnato, Dino and Oeckerath, André and Schön, Alexander and Henning, Frank
Composite Structures, ISSN 0263-8223, 11/2015, Volume 132, pp. 350 - 358
Current development of composite components made by Resin Transfer Moulding (RTM) requires numerous manual iteration steps to find the optimal design in... 
Moulding | CAE chain | Mapping | Structural simulation | Process simulation | Draping | PERMEABILITY | PART | MATERIALS SCIENCE, COMPOSITES | SIMULATION | Computer-aided engineering | Analysis | Algorithms | Computer simulation | Resin transfer molding | Chains | Fiber orientation | Molding (process) | Optimization
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12. Full Text Superoxide Radical Formation by Pure Complex I (NADH:Ubiquinone Oxidoreductase) from Yarrowia lipolytica
by Alexander Galkin and Ulrich Brandt
Journal of Biological Chemistry, ISSN 0021-9258, 08/2005, Volume 280, Issue 34, pp. 30129 - 30135
Generation of reactive oxygen species (ROS) is increasingly recognized as an important cellular process involved in numerous physiological and... 
CYTOCHROME-C | RESPIRATORY-CHAIN | HEART SUBMITOCHONDRIAL PARTICLES | REDUCED FLAVINS | CONFORMATIONAL-CHANGE | ELECTRON-TRANSFER | OXIDATION-REDUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IRON-SULFUR CENTERS | ADENINE-DINUCLEOTIDE | HYDROGEN-PEROXIDE | Quinones - chemistry | Reactive Oxygen Species | Yarrowia - metabolism | Oxidation-Reduction | Proteolipids - metabolism | Ubiquinone - metabolism | Mitochondria - metabolism | Electron Transport Complex I - metabolism | Oxygen - metabolism | Dose-Response Relationship, Drug | NAD - chemistry | Point Mutation | Superoxides - metabolism | Catalysis | Yarrowia - enzymology | NAD - metabolism | Electrons | Hydrogen-Ion Concentration
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13. Full Text Redox Signaling Through Compartmentalization of Reactive Oxygen Species: Implications for Health and Disease
by Wojtovich, Andrew P and Berry, Brandon J and Galkin, Alexander
Antioxidants & Redox Signaling, ISSN 1523-0864, 09/2019, Volume 31, Issue 9, pp. 591 - 593
The cell maintains a balance between the production and removal of reactive oxygen species (ROS). Changes in ROS levels can impact many cellular functions, and... 
Forum Editorial | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | reactive oxygen species | optogenetics | ENDOCRINOLOGY & METABOLISM | ischemia reperfusion injury | hydrogen peroxide gradients | Environmental impact | Oxygen
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14. Full Text Remodeling of actin filaments by ADF/cofilin proteins
by Vitold E. Galkin and Albina Orlova and Dmitri S. Kudryashov and Alexander Solodukhin and Emil Reisler and Gunnar F. Schröder and Edward H. Egelman
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 51, pp. 20568 - 20572
Cofilin/ADF proteins play key roles in the dynamics of actin, one of the most abundant and highly conserved eukaryotic proteins. We used cryoelectron... 
Proteins | Molecules | Yeasts | Microfilaments | Actins | Actin depolymerizing factors | Atoms | Biochemistry | Pixels | Protein subunits | Helical polymers | Electron microscopy | Cytoskeleton | F-ACTIN | cytoskeleton | MULTIDISCIPLINARY SCIENCES | CROSS-LINKING | THERMAL FLUCTUATIONS | DEPOLYMERIZING FACTOR | COFILIN | ELECTRON CRYOMICROSCOPY | CONFORMATIONAL-CHANGES | SLIDING MOVEMENT | helical polymers | electron microscopy | MONOMERIC ACTIN | BINDING | Gene Library | Protein Structure, Secondary | Humans | Molecular Conformation | Models, Molecular | Muscle, Skeletal - metabolism | Microscopy, Electron - methods | Actins - chemistry | Cofilin 2 - chemistry | Polymers - chemistry | Protein Conformation | Cryoelectron Microscopy - methods | Actin Depolymerizing Factors - chemistry | Cytoskeleton - chemistry | Physiological aspects | Muscle proteins | Actin | Methods | Eukaryotes | Models | Biological Sciences
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15. Analysis of occupational accidents at the mining enterprises of the northern regions of Russia
by Galkin, Alexander
International Multidisciplinary Scientific GeoConference Surveying Geology and Mining Ecology Management, SGEM, ISSN 1314-2704, 2014, Volume 3, Issue 1, pp. 23 - 30
On the basis of analysis of occupational accidents at mining and oil-and-gas enterprises, it has been established that the level of occupational accidents has... 
Temperature factor | Energy consumption | Occupational accidents | Labor protection | Severity of work
Conference Proceeding
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16. Full Text Ischemic A/D transition of mitochondrial complex I and its role in ROS generation
by Dröse, Stefan and Stepanova, Anna and Galkin, Alexander
BBA - Bioenergetics, ISSN 0005-2728, 07/2016, Volume 1857, Issue 7, pp. 946 - 957
Mitochondrial complex I (NADH:ubiquinone oxidoreductase) is a key enzyme in cellular energy metabolism and provides approximately 40% of the proton-motive... 
Mitochondrial complex I | Thiol redox modification | Ischemia/reperfusion injury | ROS generation | A/D transition | RESPIRATORY-CHAIN | SUPEROXIDE-PRODUCTION | BOVINE HEART-MITOCHONDRIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | OXYGEN SPECIES GENERATION | ACTIVE/DE-ACTIVE TRANSITION | UBIQUINONE-OXIDOREDUCTASE COMPLEX | BIOPHYSICS | SULFUR CLUSTER N2 | NITRIC-OXIDE | HYDROGEN-PEROXIDE PRODUCTION | ELECTRON-TRANSPORT | Electron Transport | Reactive Oxygen Species - metabolism | Models, Chemical | Oxidation-Reduction | Humans | Ischemia - metabolism | Models, Molecular | Mitochondrial Proteins - ultrastructure | Electron Transport Complex I - metabolism | Electron Transport Complex I - chemistry | Animals | Mitochondrial Proteins - metabolism | Models, Biological | Mitochondrial Proteins - chemistry | Enzyme Activation | Physiological aspects | Enzymes | Cysteine | Thiols | Cystine
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17. Full Text Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer
by Sansone, Pasquale and Savini, Claudia and Kurelac, Ivana and Chang, Qing and Amato, Laura Benedetta and Strillacci, Antonio and Stepanova, Anna and Iommarini, Luisa and Mastroleo, Chiara and Daly, Laura and Galkin, Alexander and Thakur, Basant Kumar and Soplop, Nadine and Uryu, Kunihiro and Hoshinob, Ayuko and Norton, Larry and Bonafé, Massimiliano and Cricca, Monica and Gasparre, Giuseppe and Lyden, David and Bromberg, Jacqueline
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 43, pp. E9066 - E9075
The horizontal transfer of mtDNA and its role in mediating resistance to therapy and an exit from dormancy have never been investigated. Here we identified the... 
CELLS | CAPACITY | MECHANISM | mitochondrial DNA | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | hormonal therapy | EXTRACELLULAR VESICLES | MTDNA | MICROENVIRONMENT | METABOLISM | metastasis | exosomes | CHEMORESISTANCE | cancer stem cells | GENOMIC DNA | Mitochondrial DNA | Breast cancer | Genetic aspects | Nucleotide sequencing | Health aspects | Methods | DNA sequencing | Therapy | Peripheral circulation | Phosphorylation | Estrogens | Endocrine therapy | Genomes | Metastasis | Exosomes | Patients | Metastases | Dormancy | Horizontal transfer | Restoration | Oxidative phosphorylation | Packaging | Breast | Deoxyribonucleic acid--DNA | Cancer | Biological Sciences | PNAS Plus
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18. Full Text Experiments on muon radiography with emulsion track detectors
by Aleksandrov, Andrey and Bagulya, Alexander and Baklagin, Sergei and Chernyavsky, Mikhail and Galkin, Vladimir and Grachev, Victor and Konovalova, Nina and Managadze, Alexander and Polukhina, Natalya and Roganova, Tatiana and Starkov, Nikolai and Shchedrina, Tatiana and Tioukov, Valeri and Vladymirov, Mykhailo and Zemskova, Svetlana
EPJ Web of Conferences, ISSN 2101-6275, 10/2016, Volume 125, p. 2022
Muon radiography is a method of study the internal structure of large natural and industrial objects based on sensing an object with a flux of cosmic muons... 
Radiography | Data processing | Object recognition | Nuclear physics | Detectors | Muons
Conference Proceeding
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19. Full Text The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A
by Stepanova, Anna and Konrad, Csaba and Manfredi, Giovanni and Springett, Roger and Ten, Vadim and Galkin, Alexander
Journal of Neurochemistry, ISSN 0022-3042, 03/2019, Volume 148, Issue 6, pp. 731 - 745
Oxidative stress plays an important role in ischemia/reperfusion injury when tissue oxygen level dramatically changes. We determined that H 2 O 2 release by... 
ischemia/reperfusion | generation | antimycin A | mitochondria | ROS | complex I | reverse electron transfer | ROS generation | REVERSE E