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Chemical Communications, ISSN 1359-7345, 2016, Volume 52, Issue 15, pp. 3155 - 3158
We describe a versatile and quick route to cationic gold(I) complexes containing N-heterocyclic carbenes and a second ancillary ligand (such as phosphanes,... 
CARBENE-METAL-COMPLEXES | CANCER-CELLS | CATALYSIS | PHOSPHINE | DNA | NHC | CHEMISTRY | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPEUTICS | Gold - chemistry | Methane - analogs & derivatives | Heterocyclic Compounds - chemical synthesis | Ligands | Methane - chemistry | Cations | Ruthenium - chemistry | Biotechnology | Synthesis | Cationic | Strategy | Inorganic salts | Colon | Cancer
Journal Article
Immunity, ISSN 1074-7613, 08/2009, Volume 31, Issue 2, pp. 245 - 258
Effective clearance of apoptotic cells by macrophages is essential for immune homeostasis. The transcriptional pathways that allow macrophages to sense and... 
MOLIMMUNO | CELLIMMUNO | SIGNALING PATHWAYS | IN-VITRO | PHAGOCYTOSIS | PHOSPHATIDYLSERINE RECEPTOR | LIPID-METABOLISM | MER TYROSINE KINASE | CHOLESTEROL EFFLUX | TAM RECEPTORS | IMMUNOLOGY | LIVER-X-RECEPTORS | MICE LACKING | Spleen - immunology | Receptor Protein-Tyrosine Kinases - immunology | Signal Transduction - immunology | Receptors, Cytoplasmic and Nuclear - immunology | DNA-Binding Proteins - agonists | Autoimmunity - immunology | Immune Tolerance - immunology | Liver X Receptors | c-Mer Tyrosine Kinase | Proto-Oncogene Proteins - immunology | Orphan Nuclear Receptors | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Macrophages - immunology | Proto-Oncogene Proteins - metabolism | DNA-Binding Proteins - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Phagocytosis - immunology | Receptors, Cytoplasmic and Nuclear - agonists | Receptors, Cytoplasmic and Nuclear - genetics | Spleen - cytology | Macrophages - cytology | DNA-Binding Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Mice, Knockout | Animals | Apoptosis - immunology | Spleen - metabolism | Mice | Tyrosine | Autoimmunity | Autoantibodies | Analysis | Development and progression | Macrophages | Apoptosis | Studies | Flow cytometry | Statistical analysis | Rodents | Software | Gene expression | Variance analysis | Cholesterol | Immune system
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2011, Volume 12, Issue 12, pp. 1143 - 1150
Summary Background Sunitinib is a tyrosine kinase inhibitor with proven efficacy in renal-cell carcinoma, but some patients do not respond or need dose... 
Hematology, Oncology and Palliative Medicine | SURVIVAL | VARIABILITY | INTERFERON-ALPHA | EFFICACY | ANGIOGENESIS | BIOMARKER | ONCOLOGY | GENOTYPE | VEGF | EXPRESSION | EXPOSURE | Predictive Value of Tests | Kidney Neoplasms - genetics | Prospective Studies | Humans | Middle Aged | Carcinoma, Renal Cell - genetics | Male | Antineoplastic Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Patient Selection | Sunitinib | Cytochrome P-450 CYP3A - genetics | Time Factors | Antineoplastic Agents - adverse effects | Pyrroles - adverse effects | Female | Antineoplastic Agents - pharmacokinetics | Carcinoma, Renal Cell - drug therapy | Pyrroles - therapeutic use | Precision Medicine | Protein Kinase Inhibitors - pharmacokinetics | Genetic Predisposition to Disease | Risk Assessment | Carcinoma, Renal Cell - pathology | Gene Frequency | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Logistic Models | Treatment Outcome | Spain | Disease-Free Survival | Homozygote | Phenotype | Indoles - adverse effects | Protein Kinase Inhibitors - therapeutic use | Heterozygote | Indoles - therapeutic use | Kidney Neoplasms - pathology | Aged | Polymorphism, Single Nucleotide | Kidney Neoplasms - drug therapy | Vascular Endothelial Growth Factor Receptor-3 - genetics | Genetic markers | Carcinoma | Toxicity | Oncology | Single-nucleotide polymorphism | Gene polymorphism | Protein-tyrosine kinase | Survival | Interleukin 8 | Vascular endothelial growth factor receptors | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 2139 - 10
Journal Article
European Food Research and Technology, ISSN 1438-2377, 1/2019, Volume 245, Issue 1, pp. 51 - 59
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2013, Volume 45, Issue 5, pp. 526 - 530
Journal Article
Organometallics, ISSN 0276-7333, 05/2016, Volume 35, Issue 9, pp. 1218 - 1227
We report on the synthesis, characterization, and stability studies of new titanocene complexes containing a methyl group and a carboxylate ligand (mba =... 
POTENTIAL ANTICANCER AGENTS | TRANSITION-ELEMENTS | CELLS | VIVO | CHEMISTRY | NHC | CHEMISTRY, ORGANIC | AB-INITIO PSEUDOPOTENTIALS | BIOLOGICAL-PROPERTIES | UP-REGULATION | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65541
To get further insight into the factors involved in the maintenance of genome integrity we performed a screening of Saccharomyces cerevisiae deletion strains... 
COMPLEX | ACTIVATED PROTEIN-KINASE | INSTABILITY | REPLICATION | ELONGATION | MULTIDISCIPLINARY SCIENCES | YEAST GENE | POLYADENYLATION | TOPOISOMERASE-I | QUALITY-CONTROL | SACCHAROMYCES-CEREVISIAE | Protein Structure, Tertiary | Biocatalysis | Adenosine Deaminase - metabolism | Saccharomyces cerevisiae - genetics | Humans | RNA, Messenger - genetics | DNA-Directed DNA Polymerase - chemistry | Saccharomyces cerevisiae Proteins - genetics | Mutation - genetics | RNA, Messenger - metabolism | DNA-Directed DNA Polymerase - genetics | RNA, Fungal - metabolism | Phenotype | Polyadenylation - genetics | Genome, Fungal - genetics | Recombination, Genetic | Saccharomyces cerevisiae Proteins - metabolism | Transcription, Genetic | RNA, Fungal - genetics | DNA-Directed DNA Polymerase - metabolism | Nucleic Acid Conformation | Genomic Instability - genetics | Saccharomyces cerevisiae Proteins - chemistry | Recombination | Yeast | Transcription | DNA polymerase | Genes | Ribonuclease H | Genomes | Saccharomyces | Gene deletion | DNA-directed RNA polymerase | Genomic instability | Genotype & phenotype | Clonal deletion | Cell cycle | Deletion | Genetics | Deoxyribonucleic acid--DNA | Artificial chromosomes | Metabolism | Ribonucleic acid--RNA | Mutants | Polymerase | Surveillance | Plasmids | Mutation | R-loops | Saccharomyces cerevisiae | Frequency stability | Cytidine deaminase | Integrity | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article