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BioEssays, ISSN 0265-9247, 01/2012, Volume 34, Issue 1, pp. 50 - 60
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 10/2019, Volume 47, Issue 18, pp. 9557 - 9572
Estrogen receptor α (ERα) is an enhancer activating transcription factor, a key driver of breast cancer and a main target for cancer therapy. ERα-mediated gene... 
Genetics | Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2015, Volume 60, Issue 2, pp. 328 - 337
The Hippo/YAP signaling pathway is a crucial regulator of tissue growth, stem cell activity, and tumorigenesis. However, the mechanism by which YAP controls... 
REGULATOR | COACTIVATOR | ACTIVATION | COMPLEX | CHROMATIN | YORKIE | MEDIATOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIZE | CELL | REQUIREMENT | CELL BIOLOGY | Chromatin - metabolism | Mediator Complex - metabolism | Humans | Gene Expression Regulation, Neoplastic | Intracellular Signaling Peptides and Proteins - metabolism | Cholangiocarcinoma - metabolism | DNA Polymerase II - metabolism | Phosphoproteins - metabolism | Carcinogenesis - metabolism | Piperidines - pharmacology | Transcription, Genetic | Antineoplastic Agents - pharmacology | Flavonoids - pharmacology | Bile Duct Neoplasms - genetics | DNA Polymerase II - genetics | Intracellular Signaling Peptides and Proteins - genetics | Bile Duct Neoplasms - drug therapy | Chromatin - chemistry | Bile Duct Neoplasms - metabolism | Signal Transduction | Cyclin-Dependent Kinase 9 - genetics | Carcinogenesis - genetics | Mediator Complex - genetics | Mice, Transgenic | Phosphoproteins - genetics | Carcinogenesis - drug effects | Carcinogenesis - pathology | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - drug therapy | Enhancer Elements, Genetic | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Cholangiocarcinoma - genetics | Protein Binding | Cyclin-Dependent Kinase 9 - metabolism | Mice | Bile Duct Neoplasms - pathology | Adaptor Proteins, Signal Transducing - metabolism | Genetic aspects | Genetic transcription | Growth | Analysis | Genomics | Stem cells | Yuan (China) | Chromatin
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 25, pp. 2387 - 2397
In this trial, patients with an acute coronary syndrome within the previous 10 days were randomly assigned to simvastatin plus either ezetimibe or placebo. At... 
CHOLESTEROL ABSORPTION | CARDIAC OUTCOMES | MEDICINE, GENERAL & INTERNAL | MYOCARDIAL-INFARCTION | EFFICACY | CARDIOVASCULAR OUTCOMES | CLINICAL-TRIALS | SIMVASTATIN | PRIMARY PREVENTION | IMPROVE-IT | ATORVASTATIN | Simvastatin - therapeutic use | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Azetidines - adverse effects | Ezetimibe | Kaplan-Meier Estimate | Male | Anticholesteremic Agents - adverse effects | Acute Coronary Syndrome - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Usage | Simvastatin | Analysis | Practice guidelines (Medicine) | Dosage and administration | Drug therapy, Combination | Acute coronary syndrome | Drug therapy | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Angina | Cholesterol | Intestine | Gallbladder | Acute coronary syndromes | Cardiovascular diseases | Statins | Pharmaceuticals | Cancer | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
Journal Article