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1. Full Text Genome-wide association study of colorectal cancer identifies six new susceptibility loci
by Schumacher, Fredrick R and Schmit, Stephanie L and Jiao, Shuo and Edlund, Christopher K and Wang, Hansong and Zhang, Ben and Hsu, Li and Huang, Shu-Chen and Fischer, Christopher P and Harju, John F and Idos, Gregory E and Lejbkowicz, Flavio and Manion, Frank J and McDonnell, Kevin and McNeil, Caroline E and Melas, Marilena and Rennert, Hedy S and Shi, Wei and Thomas, Duncan C and Van Den Berg, David J and Hutter, Carolyn M and Aragaki, Aaron K and Butterbach, Katja and Caan, Bette J and Carlson, Christopher S and Chanock, Stephen J and Curtis, Keith R and Fuchs, Charles S and Gala, Manish and Giocannucci, Edward L and Gogarten, Stephanie M and Hayes, Richard B and Henderson, Brian and Hunter, David J and Jackson, Rebecca D and Kolonel, Laurence N and Kooperberg, Charles and Kury, Sebastian and Lacroix, Andrea and Laurie, Cathy C and Laurie, Cecelia A and Lemire, Mathiew and Levine, David and Ma, Jing and Makar, Karen W and Qu, Conghui and Taverna, Darin and Ulrich, Cornelia M and Wu, Kana and Kono, Suminori and West, Dee W and Berndt, Sonja I and Bezieau, Stephane and Brenner, Hermann and Campbell, Peter T and Chan, Andrew T and Chang-Claude, Jenny and Coetzee, Gerhard A and Conti, David V and Duggan, David and Figueiredo, Jane C and Fortini, Barbara K and Gallinger, Steven J and Gauderman, W. James and Giles, Graham and Green, Roger and Haile, Robert and Harrison, Tabitha A and Hoffmeister, Michael and Hopper, John L and Hudson, Thomas J and Jacobs, Eric and Iwasaki, Motoki and Jee, Sun Ha and Jenkins, Mark and Jia, Wei-Hua and Joshi, Amit and Li, Li and Lindor, Noralene M and Matsuo, Keitaro and Moreno, Victor and Mukherjee, Bhramar and Newcomb, Polly A and Potter, John D and Raskin, Leon and Rennert, Gad and Rosse, Stephanie and Severi, Gianluca and Schoen, Robert E and Seminara, Daniela and Shu, Xiao-Ou and Slattery, Martha L and Tsugane, Shoichiro and White, Emily and Xiang, Yong-Bing and Zanke, Brent W and Zheng, Wei and Le Marchand, Loic and Casey, Graham and Gruber, Stephen B and ...
Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, p. 7138
Genetic susceptibility to colorectal cancer is caused by rare pathogenic mutations and common genetic variants that contribute to familial risk. Here we report... 
RISK LOCUS | 8Q24 | METAANALYSIS | VARIANTS | GENOTYPE IMPUTATION | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | RECEPTOR | NEGATIVE REGULATOR LRIG1 | SCAN | CARCINOMA | Genetic Predisposition to Disease | Genome-Wide Association Study | Colorectal Neoplasms - genetics | Humans | Polymorphism, Single Nucleotide | Odds Ratio | Case-Control Studies | Genetics | Genètica | Human genome | Càncer colorectal | Colorectal cancer | Genoma humà
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2. Full Text NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma
by Jones, MR and Williamson, LM and Topham, JT and Lee, MKC and Goytain, A and Ho, J and Denroche, RE and Jang, GH and Pleasance, E and Shen, YQ and Karasinska, JM and McGhie, JP and Gill, S and Lim, HJ and Moore, MJ and Wong, HL and Ng, T and Yip, S and Zhang, W and Sadeghi, S and Reisle, C and Mungall, AJ and Mungall, KL and Moore, RA and Ma, Y and Knox, JJ and Gallinger, S and Laskin, J and Marra, MA and Schaeffer, DF and Jones, SJM and Renouf, DJ
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2019, Volume 25, Issue 15, pp. 4674 - 4681
Purpose: Gene fusions involving neuregulin 1 (NRG1) have been noted in multiple cancer types and have potential therapeutic implications. Although varying... 
PATHWAYS | MUTATIONAL PROCESSES | SIGNATURES | ONCOLOGY | SUBTYPES | RESISTANCE | COMBINATION | CANCER | EXPRESSION
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3. Full Text Shared heritability and functional enrichment across six solid cancers
by Jiang, Xia and Finucane, H.K and Schumacher, F and Schmit, Stephanie L and Tyrer, J.P and Han, Y and Kiemeney, B and Kraft, P and Lindstrom, Sara and Medicinska fakulteten and Klinisk kemi and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 431 - 23
Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association... 
BREAST-CANCER | LUNG-CANCER | RISK-FACTORS | PARTITIONING HERITABILITY | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | GENETIC ARCHITECTURE | ANALYSES IDENTIFY | MENDELIAN RANDOMIZATION | CELL-TYPES | GENOME-WIDE ASSOCIATION | Lung Neoplasms - ethnology | Colorectal Neoplasms - genetics | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Prostatic Neoplasms - diagnosis | Case-Control Studies | Colorectal Neoplasms - diagnosis | Ovarian Neoplasms - ethnology | Inheritance Patterns | Ovarian Neoplasms - genetics | Mental Disorders - genetics | Prostatic Neoplasms - genetics | Smoking - physiopathology | Head and Neck Neoplasms - ethnology | Female | Neoplasm Proteins - genetics | Breast Neoplasms - ethnology | Lung Neoplasms - genetics | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Colorectal Neoplasms - ethnology | Ovarian Neoplasms - diagnosis | European Continental Ancestry Group | Smoking - genetics | Prostatic Neoplasms - ethnology | Head and Neck Neoplasms - pathology | Mental Disorders - physiopathology | Smoking - ethnology | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Head and Neck Neoplasms - diagnosis | Head and Neck Neoplasms - genetics | Breast Neoplasms - diagnosis | Mental Disorders - ethnology | Polymorphism, Single Nucleotide | Colorectal Neoplasms - pathology | Lung Neoplasms - diagnosis | Enrichment | Correlation | Statistical analysis | Ovarian carcinoma | Mental disorders | Lung cancer | Colorectal carcinoma | Genomes | Breast cancer | Regulatory sequences | Ovarian cancer | Etiology | Breast | Heritability | Neck | Solid tumors | Prostate cancer | Prostate | Cancer | Smoking | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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4. Full Text Telomere structure and maintenance gene variants and risk of five cancer types
by Karami, Sara and Han, Younghun and Pande, Mala and Cheng, Iona and Rudd, James and Pierce, Brandon L and Nutter, Ellen L and Schumacher, Fredrick R and Kote‐Jarai, Zsofia and Lindstrom, Sara and Witte, John S and Fang, Shenying and Han, Jiali and Kraft, Peter and Hunter, David J and Song, Fengju and Hung, Rayjean J and McKay, James and Gruber, Stephen B and Chanock, Stephen J and Risch, Angela and Shen, Hongbing and Haiman, Christopher A and Boardman, Lisa and Ulrich, Cornelia M and Casey, Graham and Peters, Ulrike and Amin Al Olama, Ali and Berchuck, Andrew and Berndt, Sonja I and Bezieau, Stephane and Brennan, Paul and Brenner, Hermann and Brinton, Louise and Caporaso, Neil and Chan, Andrew T and Chang‐Claude, Jenny and Christiani, David C and Cunningham, Julie M and Easton, Douglas and Eeles, Rosalind A and Eisen, Timothy and Gala, Manish and Gallinger, Steven J and Gayther, Simon A and Goode, Ellen L and Grönberg, Henrik and Henderson, Brian E and Houlston, Richard and Joshi, Amit D and Küry, Sébastien and Landi, Mari T and Le Marchand, Loic and Muir, Kenneth and Newcomb, Polly A and Permuth‐Wey, Jenny and Pharoah, Paul and Phelan, Catherine and Potter, John D and Ramus, Susan J and Risch, Harvey and Schildkraut, Joellen and Slattery, Martha L and Song, Honglin and Wentzensen, Nicolas and White, Emily and Wiklund, Fredrik and Zanke, Brent W and Sellers, Thomas A and Zheng, Wei and Chatterjee, Nilanjan and Amos, Christopher I and Doherty, Jennifer A and CORECT and FOCI and TRICL and DRIVE and ELLIPSE and GECCO and GAME-ON Network CORECT and GECCO and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI, and TRICL
International Journal of Cancer, ISSN 0020-7136, 12/2016, Volume 139, Issue 12, pp. 2655 - 2670
Telomeres cap chromosome ends, protecting them from degradation, double‐strand breaks, and end‐to‐end fusions. Telomeres are maintained by telomerase, a... 
lung cancer | prostate cancer | GWAS | colorectal cancer | ovarian cancer | telomere maintenance | cancer risk | breast cancer | meta‐analysis | telomere structure | meta-analysis | IMPUTATION | METAANALYSIS | LENGTH | SUSCEPTIBILITY LOCI | OVARIAN-CANCER | BREAST | IDENTIFIES 3 | ONCOLOGY | COLORECTAL-CANCER | CHROMOSOME 5P15.33 | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Genome-Wide Association Study | Genetic Association Studies | Humans | European Continental Ancestry Group | Risk | Telomere Homeostasis - genetics | Case-Control Studies | Linkage Disequilibrium | Genetic Variation | Telomerase - genetics | Neoplasms - genetics | Alleles | Polymorphism, Single Nucleotide | Odds Ratio | Neoplasms - epidemiology | Telomere - genetics | Lung cancer | Genes | Colorectal cancer | Risk factors | Ovarian cancer | Telomeres | Genetic research | Genetic aspects | Single nucleotide polymorphisms | Health aspects | Prostate cancer | Telomerase | Cancer | Arsenic | Health risk assessment | Prostate
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5. Full Text Publisher Correction: Shared heritability and functional enrichment across six solid cancers
by Jiang, Xia and Finucane, Hilary K and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Han, Younghun and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Antoniou, Antonis C and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Arun, Banu K and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benlloch, Sara and Berchuck, Andrew and Berndt, Sonja I and Bickeböller, Heike and Bien, Stephanie A and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brook, Mark N and Brunet, Joan and Brunnström, Hans and Buchanan, Daniel D and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldés, Trinidad and Caligo, Maria A and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Géraldine and Cannon-Albright, Lisa and Campa, Daniele and Caporaso, Neil and Carvalho, André L and Chan, Andrew T and Chang-Claude, Jenny and Chanock, Stephen J and Chen, Chu and Christiani, David C and Claes, Kathleen B. M and Claessens, Frank and Clements, Judith and Collée, J. Margriet and Correa, Marcia Cruz and Couch, Fergus J and Cox, Angela and Cunningham, Julie M and Cybulski, Cezary and Czene, Kamila and Daly, Mary B and deFazio, Anna and Devilee, Peter and Diez, Orland and Gago-Dominguez, Manuela and Donovan, Jenny L and Dörk, Thilo and Duell, Eric J and Dunning, Alison M and Dwek, Miriam and Eccles, Diana M and Edlund, Christopher K and Edwards, Digna R. Velez and Ellberg, Carolina and Evans, D. Gareth and Fasching, Peter A and Ferris, Robert L and Liloglou, Triantafillos and Figueiredo, Jane C and Fletcher, Olivia and Fortner, Renée T and Fostira, Florentia and Franceschi, Silvia and Friedman, Eitan and Gallinger, Steven J and Ganz, Patricia A and ...
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 8
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Heritability
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6. Full Text Comprehensive genomic analysis of metastatic pancreatic ductal adenocarcinoma (mPDAC) reveals a significant proportion of clinical actionable aberrations
by Lee, Michael and Jones, Martin R and Williamson, Laura and Topham, James Thomas and Wong, Hui-Li and Addison, Sean and Denroche, Rob and Jang, Gun Ho and Karasinska, Joanna and McGhie, John Paul and Gill, Sharlene and Lim, Howard John and Yip, Stephen and Knox, Jennifer J and Gallinger, Steven and Laskin, Janessa J and Marra, Marco A and Jones, Steven J. M and Schaeffer, David F and Renouf, Daniel John
Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e15753 - e15753
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7. Full Text Comprehensive genomic analysis of metastatic pancreatic ductal adenocarcinoma (mPDAC) reveals a significant proportion of clinical actionable aberrations
by Lee, Michael and Jones, Martin R and Williamson, Laura and Topham, James Thomas and Addison, Sean and Wong, Hui-Li and Denroche, Rob and Jang, Gun Ho and Karasinska, Joanna and McGhie, John Paul and Gill, Sharlene and Lim, Howard John and Yip, Stephen and Knox, Jennifer J and Gallinger, Steven and Laskin, Janessa J and Marra, Marco A and Jones, Steven J. M and Sschaeffer, David F and Renouf, Daniel John and POG PDAC
Journal of Clinical Oncology, ISSN 0732-183X, 02/2019, Volume 37, Issue 4_suppl, pp. 273 - 273
273 Background: Substantial progress has been made in the understanding of the genomic landscape of PDAC, but the clinical utility of these data remains... 
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8. Full Text Novel Common Genetic Susceptibility Loci for Colorectal Cancer
by Schmit, S.L and Edlund, C.K and Schumacher, F.R and Gong, Jian and Harrison, T.A and Feskens, E.J.M and Duijnhoven, van, F.J.B and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Onkologi and Umeå universitet
Journal of the National Cancer Institute, ISSN 0027-8874, 2019, Volume 111, Issue 2, pp. 146 - 157
Background: Previous genome-wide association studies (GWAS) have identified 42 loci (P < 5 × 10−8) associated with risk of colorectal cancer (CRC). Expanded... 
Nutrition and Disease | HNE Voeding en Gezondheid in de Levenscyclus | VLAG | Chair Nutrition and Health over the Lifecourse | Global Nutrition | HNE Nutrition and Disease | Wereldvoeding | Chair Nutrition and Disease | Voeding en Ziekte | HNE Voeding en Ziekte | HNE Nutrition and Health over the Lifecourse | RISK LOCUS | METAANALYSIS | VARIANTS | TERT | ONCOLOGY | ARCHITECTURE | GENOME-WIDE ASSOCIATION | IDENTIFIES 6 | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
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9. Full Text DNA repair and cancer in colon and rectum: Novel players in genetic susceptibility
by Pardini, Barbara and Corrado, Alda and Paolicchi, Elisa and Cugliari, Giovanni and Berndt, Sonja I and Bezieau, Stephane and Bien, Stephanie A and Brenner, Hermann and Caan, Bette J and Campbell, Peter T and Casey, Graham and Chan, Andrew T and Chang‐Claude, Jenny and Cotterchio, Michelle and Gala, Manish and Gallinger, Steven J and Haile, Robert W and Harrison, Tabitha A and Hayes, Richard B and Hoffmeister, Michael and Hopper, John L and Hsu, Li and Huyghe, Jeroen and Jenkins, Mark A and Le Marchand, Loic and Lin, Yi and Lindor, Noralane M and Nan, Hongmei and Newcomb, Polly A and Ogino, Shuji and Potter, John D and Schoen, Robert E and Slattery, Martha L and White, Emily and Vodickova, Ludmila and Vymetalkova, Veronika and Vodicka, Pavel and Gemignani, Federica and Peters, Ulrike and Naccarati, Alessio and Landi, Stefano
International Journal of Cancer, ISSN 0020-7136, 01/2020, Volume 146, Issue 2, pp. 363 - 372
Interindividual differences in DNA repair systems may play a role in modulating the individual risk of developing colorectal cancer. To better ascertain the... 
genome‐wide association studies | cancer susceptibility | single nucleotide polymorphisms | DNA repair | colon cancer | rectal cancer | Genes | Homologous recombination | Colorectal carcinoma | Colorectal cancer | Risk | Homology | Single-nucleotide polymorphism | Nucleotides | Epidemiology | Carcinogenesis | Goodness of fit | O6-methylguanine-DNA methyltransferase | Consortia | Carcinogens | Colon cancer | Mismatch repair | Genetics | Colon | Repair | Deoxyribonucleic acid--DNA | MLH1 protein | Health risks | Genetic diversity | Gene expression | Rectum | Health risk assessment | Cancer
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10. Full Text Smoking is associated with risks of molecular subtypes of colorectal cancer
by Wang, Xiaoliang and Amitay, Efrat and Banbury, Barbara L and Brenner, Hermann and Buchanan, Daniel D and Campbell, Peter T and Chang-Claude, Jenny and Gallinger, Steven J and Giles, Graham G and Harrison, Tabitha A and Hopper, John L and Jenkins, Mark A and Lin, Yi and Nishihara, Reiko and Newcomb, Polly A and Ogino, Shuji and Sakoda, Lori C and Schoen, Robert E and Slattery, Martha L and Thibodeau, Steven N and van Guelpen, Bethany and Woods, Michael O and Hsu, Li and Hoffmeister, Michael and Peters, Ulrike and Medicinska fakulteten and Institutionen för strålningsvetenskaper and Umeå universitet
Cancer Research, ISSN 0008-5472, 2019, Volume 79, Issue 13
Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
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11. Full Text Shared heritability and functional enrichment across six solid cancers
by Jiang, Xia and Finucane, Hilary K and Schumacher, Fredrick R and Schmit, Stephanie L and Tyrer, Jonathan P and Han, Younghun and Michailidou, Kyriaki and Lesseur, Corina and Kuchenbaecker, Karoline B and Dennis, Joe and Conti, David V and Casey, Graham and Gaudet, Mia M and Huyghe, Jeroen R and Albanes, Demetrius and Aldrich, Melinda C and Andrew, Angeline S and Andrulis, Irene L and Anton-Culver, Hoda and Antoniou, Antonis C and Antonenkova, Natalia N and Arnold, Susanne M and Aronson, Kristan J and Arun, Banu K and Bandera, Elisa V and Barkardottir, Rosa B and Barnes, Daniel R and Batra, Jyotsna and Beckmann, Matthias W and Benitez, Javier and Benlloch, Sara and Berchuck, Andrew and Berndt, Sonja I and Bickeboeller, Heike and Bien, Stephanie A and Blomqvist, Carl and Boccia, Stefania and Bogdanova, Natalia V and Bojesen, Stig E and Bolla, Manjeet K and Brauch, Hiltrud and Brenner, Hermann and Brenton, James D and Brook, Mark N and Brunet, Joan and Brunnstrom, Hans and Buchanan, Daniel D and Burwinkel, Barbara and Butzow, Ralf and Cadoni, Gabriella and Caldes, Trinidad and Caligo, Maria A and Campbell, Ian and Campbell, Peter T and Cancel-Tassin, Geraldine and Cannon-Albright, Lisa and Campa, Daniele and Caporaso, Neil and Carvalho, Andre L and Chan, Andrew T and Chang-Claude, Jenny and Chanock, Stephen J and Chen, Chu and Christiani, David C and Claes, Kathleen B. M and Claessens, Frank and Clements, Judith and Collee, J. Margriet and Correa, Marcia Cruz and Couch, Fergus J and Cox, Angela and Cunningham, Julie M and Cybulski, Cezary and Czene, Kamila and Daly, Mary B and defazio, Anna and Devilee, Peter and Diez, Orland and Gago-Dominguez, Manuela and Donovan, Jenny L and Doerk, Thilo and Duell, Eric J and Dunning, Alison M and Dwek, Miriam and Eccles, Diana M and Edlund, Christopher K and Edwards, Digna R. Velez and Ellberg, Carolina and Evans, D. Gareth and Fasching, Peter A and Ferris, Robert L and Liloglou, Triantafillos and Figueiredo, Jane C and Fletcher, Olivia and Fortner, Renee T and Fostira, Florentia and Franceschi, Silvia and Friedman, Eitan and Gallinger, Steven J and Ganz, Patricia A and ... and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature Communications, ISSN 2041-1723, 2019, Volume 10
Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association... 
Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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12. Full Text Abstract 245: Genetic variation related to innate immunity and colorectal cancer risk
by Citronberg, Jessica and Banbury, Barbara and Chan, Andrew T and Campbell, Peter T and Casey, Graham and Chang-Claude, Jenny and Gallinger, Steven J and Harrison, Tabitha and Hoffmeister, Michael and Jenkins, Mark A and Marchand, Loic Le and Nan, Hongmei and Jiao, Li and Schoen, Robert E and Brenner, Hermann and White, Emily and Peters, Ulrike and Newcomb, Polly A
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 245 - 245
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13. Full Text Abstract 2965: Functionally informed genome-wide interaction analysis of nonsteroidal anti-inflammatory drugs on colorectal cancer risk
by Wang, Xiaoliang and Su, Yu-Ru and Chan, Andrew T and Bien, Stephanie and Bernt, Sonja I and Brenner, Hermann and Casey, Graham and Chang-Claude, Jenny and Gallinger, Steven J and Haile, Robert W and Harrison, Tabitha A and Hoffmeister, Michael and Jenkins, Mark A and Joshi, Amit and Lin, Yi and Lindor, Noralane M and Marchand, Loic Le and Nan, Hongmei and Newcomb, Polly A and Potter, John D and Slattery, Martha L and Thibodeau, Steve N and White, Emily and Hsu, Li and Peters, Ulrike
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 2965 - 2965
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