The New England Journal of Medicine, ISSN 0028-4793, 12/2010, Volume 363, Issue 26, pp. 2499 - 2510
In this clinical trial, rivaroxaban, an oral factor Xa inhibitor, was effective in the initial and continued treatment of symptomatic venous thromboembolism;...
MEDICINE, GENERAL & INTERNAL | FACTOR-XA INHIBITOR | THERAPY | DISEASE | PREVENTION | DEEP-VEIN THROMBOSIS | IDRAPARINUX | Thiophenes - therapeutic use | Factor Xa Inhibitors | Thiophenes - adverse effects | Humans | Middle Aged | Warfarin - adverse effects | Male | Enoxaparin - therapeutic use | Enoxaparin - adverse effects | Venous Thromboembolism - drug therapy | Warfarin - therapeutic use | Rivaroxaban | Vitamin K - antagonists & inhibitors | Injections, Subcutaneous | Female | Morpholines - adverse effects | Morpholines - therapeutic use | Acute Disease | Double-Blind Method | Venous Thrombosis - drug therapy | Administration, Oral | Kaplan-Meier Estimate | Anticoagulants - therapeutic use | Anticoagulants - adverse effects | Acenocoumarol - adverse effects | Intention to Treat Analysis | Pulmonary Embolism - drug therapy | Acenocoumarol - therapeutic use | Aged | Hemorrhage - chemically induced | Anticoagulants (Medicine) | Thromboembolism | Drug therapy | Health aspects | Risk factors | Anticoagulants | Bone surgery | Veins & arteries | Venous Thrombosis | Factor Xa | Hemorrhage | Life Sciences | Venous Thromboembolism | Thiophenes | Acenocoumarol | Vitamin K | Warfarin | Enoxaparin | Morpholines | Human health and pathology | Pulmonary Embolism | MEDICIN OCH HÄLSOVETENSKAP | Oral | MEDICAL AND HEALTH SCIENCES | Administration | chemically induced | drug therapy | Subcutaneous | antagonists & inhibitors | Injections | adverse effects | therapeutic use
MEDICINE, GENERAL & INTERNAL | FACTOR-XA INHIBITOR | THERAPY | DISEASE | PREVENTION | DEEP-VEIN THROMBOSIS | IDRAPARINUX | Thiophenes - therapeutic use | Factor Xa Inhibitors | Thiophenes - adverse effects | Humans | Middle Aged | Warfarin - adverse effects | Male | Enoxaparin - therapeutic use | Enoxaparin - adverse effects | Venous Thromboembolism - drug therapy | Warfarin - therapeutic use | Rivaroxaban | Vitamin K - antagonists & inhibitors | Injections, Subcutaneous | Female | Morpholines - adverse effects | Morpholines - therapeutic use | Acute Disease | Double-Blind Method | Venous Thrombosis - drug therapy | Administration, Oral | Kaplan-Meier Estimate | Anticoagulants - therapeutic use | Anticoagulants - adverse effects | Acenocoumarol - adverse effects | Intention to Treat Analysis | Pulmonary Embolism - drug therapy | Acenocoumarol - therapeutic use | Aged | Hemorrhage - chemically induced | Anticoagulants (Medicine) | Thromboembolism | Drug therapy | Health aspects | Risk factors | Anticoagulants | Bone surgery | Veins & arteries | Venous Thrombosis | Factor Xa | Hemorrhage | Life Sciences | Venous Thromboembolism | Thiophenes | Acenocoumarol | Vitamin K | Warfarin | Enoxaparin | Morpholines | Human health and pathology | Pulmonary Embolism | MEDICIN OCH HÄLSOVETENSKAP | Oral | MEDICAL AND HEALTH SCIENCES | Administration | chemically induced | drug therapy | Subcutaneous | antagonists & inhibitors | Injections | adverse effects | therapeutic use
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2012, Volume 366, Issue 14, pp. 1287 - 1297
In the treatment of patients with acute pulmonary embolism, the efficacy of rivaroxaban, a factor Xa inhibitor, was similar to that of traditional...
XA INHIBITOR RIVAROXABAN | MEDICINE, GENERAL & INTERNAL | DEEP-VEIN THROMBOSIS | VENOUS THROMBOEMBOLISM | WARFARIN | MOLECULAR-WEIGHT HEPARIN | Recurrence | Thiophenes - therapeutic use | Follow-Up Studies | Thiophenes - adverse effects | Humans | Middle Aged | Male | Enoxaparin - therapeutic use | Enoxaparin - adverse effects | Rivaroxaban | Vitamin K - antagonists & inhibitors | Female | Drug Therapy, Combination | Morpholines - adverse effects | Morpholines - therapeutic use | Administration, Oral | Kaplan-Meier Estimate | Anticoagulants - therapeutic use | Treatment Outcome | Anticoagulants - adverse effects | International Normalized Ratio | Pulmonary Embolism - mortality | Pulmonary Embolism - drug therapy | Aged | Hemorrhage - chemically induced | Pulmonary embolism | Drugs | Dose-response relationship (Biochemistry) | Dosage and administration | Product/Service Evaluations | Drug therapy | Anticoagulants | Embolisms | Pulmonary arteries | Thrombosis | Bone surgery | Patients | Bleeding | Embolism | Hepatitis | Blood pressure | Thromboembolism | Health risk assessment | Veins & arteries | Vitamin K | Enoxaparin | Morpholines | Hemorrhage | Life Sciences | Human health and pathology | Thiophenes | Pulmonary Embolism
XA INHIBITOR RIVAROXABAN | MEDICINE, GENERAL & INTERNAL | DEEP-VEIN THROMBOSIS | VENOUS THROMBOEMBOLISM | WARFARIN | MOLECULAR-WEIGHT HEPARIN | Recurrence | Thiophenes - therapeutic use | Follow-Up Studies | Thiophenes - adverse effects | Humans | Middle Aged | Male | Enoxaparin - therapeutic use | Enoxaparin - adverse effects | Rivaroxaban | Vitamin K - antagonists & inhibitors | Female | Drug Therapy, Combination | Morpholines - adverse effects | Morpholines - therapeutic use | Administration, Oral | Kaplan-Meier Estimate | Anticoagulants - therapeutic use | Treatment Outcome | Anticoagulants - adverse effects | International Normalized Ratio | Pulmonary Embolism - mortality | Pulmonary Embolism - drug therapy | Aged | Hemorrhage - chemically induced | Pulmonary embolism | Drugs | Dose-response relationship (Biochemistry) | Dosage and administration | Product/Service Evaluations | Drug therapy | Anticoagulants | Embolisms | Pulmonary arteries | Thrombosis | Bone surgery | Patients | Bleeding | Embolism | Hepatitis | Blood pressure | Thromboembolism | Health risk assessment | Veins & arteries | Vitamin K | Enoxaparin | Morpholines | Hemorrhage | Life Sciences | Human health and pathology | Thiophenes | Pulmonary Embolism
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2007, Volume 357, Issue 11, pp. 1094 - 1104
The long-acting factor X inhibitor idraparinux was compared with a standard antithrombotic regimen in two randomized trials, one for the treatment of deep...
HEPARIN | MEDICINE, GENERAL & INTERNAL | THROMBOSIS | Recurrence | Follow-Up Studies | Venous Thrombosis - drug therapy | Humans | Middle Aged | Oligosaccharides - therapeutic use | Venous Thrombosis - mortality | Anticoagulants - therapeutic use | Heparin - therapeutic use | Male | Oligosaccharides - adverse effects | Treatment Outcome | Anticoagulants - adverse effects | Heparin - adverse effects | Incidence | Pulmonary Embolism - mortality | Vitamin K - antagonists & inhibitors | Female | Pulmonary Embolism - drug therapy | Hemorrhage - chemically induced | Thrombophlebitis | Anticoagulants (Medicine) | Drug therapy | Health aspects | Comparative studies | Clinical trials | Medical research | Inhibitor drugs | Blood clots | Anticoagulants | Venous Thrombosis | Pharmacology | Oligosaccharides | Hemorrhage | Life Sciences | Pulmonary Embolism | Heparin | Pharmaceutical sciences | Vitamin K
HEPARIN | MEDICINE, GENERAL & INTERNAL | THROMBOSIS | Recurrence | Follow-Up Studies | Venous Thrombosis - drug therapy | Humans | Middle Aged | Oligosaccharides - therapeutic use | Venous Thrombosis - mortality | Anticoagulants - therapeutic use | Heparin - therapeutic use | Male | Oligosaccharides - adverse effects | Treatment Outcome | Anticoagulants - adverse effects | Heparin - adverse effects | Incidence | Pulmonary Embolism - mortality | Vitamin K - antagonists & inhibitors | Female | Pulmonary Embolism - drug therapy | Hemorrhage - chemically induced | Thrombophlebitis | Anticoagulants (Medicine) | Drug therapy | Health aspects | Comparative studies | Clinical trials | Medical research | Inhibitor drugs | Blood clots | Anticoagulants | Venous Thrombosis | Pharmacology | Oligosaccharides | Hemorrhage | Life Sciences | Pulmonary Embolism | Heparin | Pharmaceutical sciences | Vitamin K
Journal Article
Medical Journal of Australia, ISSN 0025-729X, 03/2013, Volume 198, Issue 4, pp. 198 - 199
For most warfarin indications, the target international normalised ratio (INR) is 2.0–3.0 (venous thromboembolism and single mechanical heart valve excluding...
Hematologic diseases | MEDICINE, GENERAL & INTERNAL | Antifibrinolytic Agents - therapeutic use | Plasma | Anticoagulants - administration & dosage | Drug Administration Schedule | Administration, Oral | Surgical Procedures, Operative | Humans | Hemorrhage - prevention & control | International Normalized Ratio - standards | Warfarin - administration & dosage | Drug Monitoring - standards | Dose-Response Relationship, Drug | Postoperative Care | Vitamin K 1 - therapeutic use | Blood Coagulation Factors - therapeutic use | Hemorrhage - chemically induced | Drugs | Care and treatment | Practice guidelines (Medicine) | Anticoagulants (Medicine) | Product/Service Evaluations | Health aspects | Thrombosis | Blood clot
Hematologic diseases | MEDICINE, GENERAL & INTERNAL | Antifibrinolytic Agents - therapeutic use | Plasma | Anticoagulants - administration & dosage | Drug Administration Schedule | Administration, Oral | Surgical Procedures, Operative | Humans | Hemorrhage - prevention & control | International Normalized Ratio - standards | Warfarin - administration & dosage | Drug Monitoring - standards | Dose-Response Relationship, Drug | Postoperative Care | Vitamin K 1 - therapeutic use | Blood Coagulation Factors - therapeutic use | Hemorrhage - chemically induced | Drugs | Care and treatment | Practice guidelines (Medicine) | Anticoagulants (Medicine) | Product/Service Evaluations | Health aspects | Thrombosis | Blood clot
Journal Article
Medical Journal of Australia, ISSN 0025-729X, 11/2004, Volume 181, Issue 9, pp. 492 - 497
For most warfarin indications, the target maintenance international normalised ratio (INR) is 2–3. Risk factors for bleeding complications with warfarin use...
Hematologic diseases | Pharmaceutical preparations | 10-MG | MEDICINE, GENERAL & INTERNAL | THERAPY | VENOUS THROMBOEMBOLISM | ANTICOAGULANT TREATMENT | HEMORRHAGIC COMPLICATIONS | VITAMIN-K | INTENSITY | RANDOMIZED-TRIAL | ATRIAL-FIBRILLATION | BLEEDING COMPLICATIONS | Plasma | Anticoagulants - administration & dosage | Thromboembolism - chemically induced | Humans | Warfarin - adverse effects | Hemorrhage - prevention & control | Drug Monitoring - methods | Warfarin - administration & dosage | Patient Selection | Thromboembolism - prevention & control | Vitamin K 1 - therapeutic use | Perioperative Care - standards | Adult | Drug Administration Schedule | Administration, Oral | Risk Factors | International Normalized Ratio - methods | International Normalized Ratio - standards | Anticoagulants - adverse effects | Evidence-Based Medicine | Drug Monitoring - standards | Warfarin - pharmacokinetics | Hemorrhage - drug therapy | Blood Coagulation Factors - therapeutic use | Patient Education as Topic - standards | Perioperative Care - methods | Anticoagulants - pharmacokinetics | Hemorrhage - chemically induced | Care and treatment | Warfarin | Research | Thrombosis | Blood clot
Hematologic diseases | Pharmaceutical preparations | 10-MG | MEDICINE, GENERAL & INTERNAL | THERAPY | VENOUS THROMBOEMBOLISM | ANTICOAGULANT TREATMENT | HEMORRHAGIC COMPLICATIONS | VITAMIN-K | INTENSITY | RANDOMIZED-TRIAL | ATRIAL-FIBRILLATION | BLEEDING COMPLICATIONS | Plasma | Anticoagulants - administration & dosage | Thromboembolism - chemically induced | Humans | Warfarin - adverse effects | Hemorrhage - prevention & control | Drug Monitoring - methods | Warfarin - administration & dosage | Patient Selection | Thromboembolism - prevention & control | Vitamin K 1 - therapeutic use | Perioperative Care - standards | Adult | Drug Administration Schedule | Administration, Oral | Risk Factors | International Normalized Ratio - methods | International Normalized Ratio - standards | Anticoagulants - adverse effects | Evidence-Based Medicine | Drug Monitoring - standards | Warfarin - pharmacokinetics | Hemorrhage - drug therapy | Blood Coagulation Factors - therapeutic use | Patient Education as Topic - standards | Perioperative Care - methods | Anticoagulants - pharmacokinetics | Hemorrhage - chemically induced | Care and treatment | Warfarin | Research | Thrombosis | Blood clot
Journal Article
Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9811, pp. 123 - 129
Summary Background Treatment of pulmonary embolism with low-molecular-weight heparin and vitamin K antagonists, such as warfarin, is not ideal. We aimed to...
Internal Medicine | MEDICINE, GENERAL & INTERNAL | DEEP-VEIN THROMBOSIS | ANTITHROMBOTIC THERAPY | Acute Disease | Anticoagulants - administration & dosage | Double-Blind Method | Humans | Middle Aged | Male | Warfarin - administration & dosage | Enoxaparin - administration & dosage | Adolescent | Intention to Treat Analysis | Aged, 80 and over | Factor X - antagonists & inhibitors | Adult | Female | Pulmonary Embolism - drug therapy | Aged | Drug Therapy, Combination | Biotin - administration & dosage | Biotin - analogs & derivatives | Oligosaccharides - administration & dosage | Pulmonary embolism | Heparin | Research | Drug therapy | Health aspects | Complications and side effects | Warfarin | Enoxaparin | Dosage and administration | Studies | Anticoagulants | Medical imaging | Drug dosages | Biotin | Oligosaccharides | Life Sciences | Human health and pathology | Factor X | Pulmonary Embolism
Internal Medicine | MEDICINE, GENERAL & INTERNAL | DEEP-VEIN THROMBOSIS | ANTITHROMBOTIC THERAPY | Acute Disease | Anticoagulants - administration & dosage | Double-Blind Method | Humans | Middle Aged | Male | Warfarin - administration & dosage | Enoxaparin - administration & dosage | Adolescent | Intention to Treat Analysis | Aged, 80 and over | Factor X - antagonists & inhibitors | Adult | Female | Pulmonary Embolism - drug therapy | Aged | Drug Therapy, Combination | Biotin - administration & dosage | Biotin - analogs & derivatives | Oligosaccharides - administration & dosage | Pulmonary embolism | Heparin | Research | Drug therapy | Health aspects | Complications and side effects | Warfarin | Enoxaparin | Dosage and administration | Studies | Anticoagulants | Medical imaging | Drug dosages | Biotin | Oligosaccharides | Life Sciences | Human health and pathology | Factor X | Pulmonary Embolism
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2016, Volume 115, Issue 4, pp. 809 - 816
Summary Risks of recurrence and bleeding are highest during the first weeks of anticoagulant therapy for venous thromboembolism (VTE). We therefore examined...
Stroke, Systemic or Venous Thromboembolism
Stroke, Systemic or Venous Thromboembolism
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2007, Volume 357, Issue 11, pp. 1105 - 1112
The high risk of recurrent venous thromboembolism in patients with idiopathic venous thrombosis or pulmonary embolism is reason for extended thromboprophylaxis...
LONG-TERM | MEDICINE, GENERAL & INTERNAL | FONDAPARINUX | THROMBOSIS | WARFARIN | EPISODE | PULMONARY-EMBOLISM | DISEASE | INITIAL TREATMENT | ORAL ANTICOAGULANT-THERAPY | SECONDARY PREVENTION | Anticoagulants - administration & dosage | Factor Xa Inhibitors | Follow-Up Studies | Humans | Middle Aged | Male | Secondary Prevention | Vitamin K - antagonists & inhibitors | Injections, Subcutaneous | Female | Oligosaccharides - administration & dosage | Double-Blind Method | Drug Administration Schedule | Venous Thrombosis - drug therapy | Oligosaccharides - therapeutic use | Kaplan-Meier Estimate | Venous Thrombosis - mortality | Anticoagulants - therapeutic use | Oligosaccharides - adverse effects | Treatment Outcome | Anticoagulants - adverse effects | Pulmonary Embolism - mortality | Pulmonary Embolism - drug therapy | Aged | Hemorrhage - chemically induced | Thrombophlebitis | Hemorrhage | Health aspects | Risk factors | Vitamin K | Studies | Anticoagulants | Pulmonary arteries | Blood pressure | Drug therapy | Drug dosages | Blood clots | Recurrence | Venous Thrombosis | Factor Xa | Pharmacology | Oligosaccharides | Life Sciences | Pulmonary Embolism | Kaplan-Meiers Estimate | Pharmaceutical sciences
LONG-TERM | MEDICINE, GENERAL & INTERNAL | FONDAPARINUX | THROMBOSIS | WARFARIN | EPISODE | PULMONARY-EMBOLISM | DISEASE | INITIAL TREATMENT | ORAL ANTICOAGULANT-THERAPY | SECONDARY PREVENTION | Anticoagulants - administration & dosage | Factor Xa Inhibitors | Follow-Up Studies | Humans | Middle Aged | Male | Secondary Prevention | Vitamin K - antagonists & inhibitors | Injections, Subcutaneous | Female | Oligosaccharides - administration & dosage | Double-Blind Method | Drug Administration Schedule | Venous Thrombosis - drug therapy | Oligosaccharides - therapeutic use | Kaplan-Meier Estimate | Venous Thrombosis - mortality | Anticoagulants - therapeutic use | Oligosaccharides - adverse effects | Treatment Outcome | Anticoagulants - adverse effects | Pulmonary Embolism - mortality | Pulmonary Embolism - drug therapy | Aged | Hemorrhage - chemically induced | Thrombophlebitis | Hemorrhage | Health aspects | Risk factors | Vitamin K | Studies | Anticoagulants | Pulmonary arteries | Blood pressure | Drug therapy | Drug dosages | Blood clots | Recurrence | Venous Thrombosis | Factor Xa | Pharmacology | Oligosaccharides | Life Sciences | Pulmonary Embolism | Kaplan-Meiers Estimate | Pharmaceutical sciences
Journal Article
Lancet, ISSN 0140-6736, 01/2012, Volume 379, Issue 9811, pp. 123 - 129
Journal Article
Thrombosis and haemostasis, ISSN 0340-6245, 2016, Volume 115, Issue 4, pp. 809 - 816
Risks of recurrence and bleeding are highest during the first weeks of anticoagulant therapy for venous thromboembolism (VTE). We therefore examined the early...
Pulmonary embolism | Venous thrombosis | Anticoagulant therapy | FONDAPARINUX | SAFETY | DEEP-VEIN THROMBOSIS | INITIAL TREATMENT | RISK | HEPARIN | DABIGATRAN | VENOUS THROMBOEMBOLISM | WARFARIN | PERIPHERAL VASCULAR DISEASE | pulmonary embolism | HEMATOLOGY | STANDARD THERAPY | anticoagulant therapy | Recurrence | Pyrazoles - therapeutic use | Follow-Up Studies | Hemorrhage - epidemiology | Humans | Middle Aged | Male | Risk | Treatment Outcome | Enoxaparin - therapeutic use | Venous Thromboembolism - drug therapy | Warfarin - therapeutic use | Hemorrhage - etiology | Venous Thromboembolism - complications | Adult | Female | Aged | Pyridones - therapeutic use
Pulmonary embolism | Venous thrombosis | Anticoagulant therapy | FONDAPARINUX | SAFETY | DEEP-VEIN THROMBOSIS | INITIAL TREATMENT | RISK | HEPARIN | DABIGATRAN | VENOUS THROMBOEMBOLISM | WARFARIN | PERIPHERAL VASCULAR DISEASE | pulmonary embolism | HEMATOLOGY | STANDARD THERAPY | anticoagulant therapy | Recurrence | Pyrazoles - therapeutic use | Follow-Up Studies | Hemorrhage - epidemiology | Humans | Middle Aged | Male | Risk | Treatment Outcome | Enoxaparin - therapeutic use | Venous Thromboembolism - drug therapy | Warfarin - therapeutic use | Hemorrhage - etiology | Venous Thromboembolism - complications | Adult | Female | Aged | Pyridones - therapeutic use
Journal Article
Medical Journal of Australia, ISSN 0025-729X, 12/2014, Volume 201, Issue 11, pp. 645 - 645
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 01/2011, Volume 9, Issue 1, pp. 92 - 99
Journal Article