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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 19, pp. 7916 - 7921
It is well-established that subcompartments of endoplasmic reticulum (ER) are in physical contact with the mitochondria. These lipid raft-like regions of ER... 
Brain | Mitochondria | Neuroscience | Disease models | Neurons | Small interfering RNA | Lipids | Physiological regulation | Alzheimers disease | Cells | Human cortical brain tissue | Hippocampal neurons | AD mouse models | RAT-LIVER | ACTIVATION | MULTIDISCIPLINARY SCIENCES | HIPPOCAMPAL | MEMBRANES | hippocampal neurons | CA2 | human cortical brain tissue | A-BETA | NEURONS | LONG-TERM POTENTIATION | RECEPTORS | Cricetinae | Receptor Cross-Talk | Calcium - metabolism | Membrane Microdomains - metabolism | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Mitochondria - metabolism | Subcellular Fractions - metabolism | Gene Knockdown Techniques | Brain - metabolism | Hippocampus - metabolism | Animals | Amyloid - metabolism | Alzheimer Disease - metabolism | Cell Line, Tumor | Inositol 1,4,5-Trisphosphate Receptors | Mice | Neurons - metabolism | Mutation | Receptors, sigma - metabolism | CHO Cells | Disease Models, Animal | RNA, Small Interfering - metabolism | Physiological aspects | Hippocampus (Brain) | Endoplasmic reticulum | Health aspects | Alzheimer's disease | Biological Sciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medical Biotechnology | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, p. e18568
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset, autosomal dominant familial Parkinson's disease (PD) and also contribute to... 
DISEASE-ASSOCIATED MUTATIONS | KINASE-ACTIVITY | R1441C MUTATION | LOCALIZATION | GENE LRRK2 | MODELS | MULTIDISCIPLINARY SCIENCES | NEURODEGENERATION | ALPHA-SYNUCLEIN | GTP-BINDING | PARKINSONS-DISEASE | Mesencephalon - metabolism | Humans | Mice, Transgenic | Mutant Proteins - metabolism | Chromatography, High Pressure Liquid | Motor Activity | Autophagy | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Protein Transport | Behavior, Animal | Neurites - pathology | Animals | Neurites - ultrastructure | Amino Acid Substitution - genetics | Mice | Dopamine - metabolism | Organ Culture Techniques | Protein-Serine-Threonine Kinases - metabolism | Mesencephalon - pathology | Mesencephalon - ultrastructure | Neurons | Genetic aspects | Neurosciences | Parkinson's disease | Parkinsons disease | Biology | Leucine | Kinases | Complexity | Engineering | Mitochondria | Neurodegeneration | Transgenic animals | Rodents | Genetics | Life sciences | Degeneration | LRRK2 protein | Age | Movement disorders | Dopamine receptors | Medical research | Dopamine | Neurodegenerative diseases | Research & development--R&D | Abnormalities | Transgenic mice | Gene expression | Mutants | Medicine | Neurology | Pathology | Brain research | Microscopy | Stem cells | Mutation | Alzheimers disease | Neurotransmission | Cancer | Research & development | R&D
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Journal Article
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by Gerstein, Hertzel C and Colhoun, Helen M and Dagenais, Gilles and Dagenais, Gilles R and Diaz, Rafael and Diaz, Sarahy and Lakshmanan, Mark and Pais, Prem and Probstfield, Jeffrey and Riesmeyer, Jeffrey S and Riddle, Matthew C and Rydén, Lars and Xavier, Denis and Atisso, Charles Messan and Dyal, Leanne and Hall, Stephanie and Hall, Charles and Rao-Melacini, Purnima and Wong, Gloria and Avezum, Alvaro and Basile, Jan and Chung, Ming-Min and Chung, Namsik and Chung, Jin-Wook and Conget, Ignacio and Cushman, William C and Franek, Edward and Hancu, Nicolae and Hanefeld, Christoph and Hanefeld, Markolf and Holt, Shaun and Jansky, Petr and Keltai, Matyas and Keltai, Katalin and Lanas, Fernando and Leiter, Lawrence A and Lopez-Jaramillo, Patricio and Cardona Munoz, Ernesto German and Pirags, Valdis and Pogosova, Nana and Raubenheimer, Peter J and Shaw, Jonathan E and Sheu, Wayne H-H and Temelkova-Kurktschiev, Theodora and Abella, Mercedes and Alebuena, Andrea and Almagro, Sandra and Amoroso, Eduardo and Anadon, Paula and Andreu, Elizabeth and Aristimuño, Guillermo and Arzadun, Maria and Barbieri, Maria and Barcudi, Raul and Bartolacci, Ines and Bolobanich, Gabriel and Bordonava, Anselmo and Bustamante Labarta, Miguel and Bustos, Betina and Caccavo, Alberto and Camino, Alejandra and Cantero, Maria and Carignano, Maria and Cartasegna, Luis and Cipullo, Marcela and Commendatore, Víctor and Conosciuto, Victoria and Costamagna, Osvaldo and Crespo, Claudia and Cuello, Jose and Cuneo, Carlos and Cusimano, Sandra and Dean, Sofia and Dituro, Claudio and Dominguez, Andrea and Farah, Miguel and Fernandez, Alberto and Fernandez, Florencia and Ferrari, Adriana and Flammia, Patricia and Fuentealba, Jose and Gallardo, Karina Beatriz and Garcia, Mar and Garcia, Celso and Garcia, Maria and Garcia Duran, Ruben and Garrido, Marcelo and Gavicola, Rodolfo and Gerbaudo, Claudio and Gilli, Graciela and Giotto, Ana Paula and Godoy Bolzán, Pedro and Gomez Vilamajo, Oscar and Guerlloy, Fernando and Guridi, Cristian and Gutierrez Garrido, Narcisa and Hasbani, Eduardo and Hermida, Sonia and Hominal, Miguel and Hrabar, Adrian and ... and REWIND Investigators
The Lancet, ISSN 0140-6736, 07/2019, Volume 394, Issue 10193, pp. 121 - 130
Journal Article