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1. Full Text One-lung ventilation with high tidal volumes and zero positive end-expiratory pressure is injurious in the isolated rabbit lung model
by De Abreu, Marcelo Gama and Heintz, Manuel and Heller, Axel and Széchényi, Roswitha and Albrecht, Detlev Michael and Koch, Thea
Anesthesia and analgesia, ISSN 0003-2999, 01/2003, Volume 96, Issue 1, pp. 220 - 228
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2. Full Text Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data
by Neto, Ary Serpa, Prof and Hemmes, Sabrine N T, MD and Barbas, Carmen S V, Prof and Beiderlinden, Martin, MD and Fernandez-Bustamante, Ana, MD and Futier, Emmanuel, Prof and Gajic, Ognjen, Prof and El-Tahan, Mohamed R, MD and Ghamdi, Abdulmohsin A Al, MD and Günay, Ersin, MD and Jaber, Samir, Prof and Kokulu, Serdar, MD and Kozian, Alf, MD and Licker, Marc, MD and Lin, Wen-Qian, MD and Maslow, Andrew D, MD and Memtsoudis, Stavros G, MD and Miranda, Dinis Reis, MD and Moine, Pierre, MD and Ng, Thomas, MD and Paparella, Domenico, MD and Ranieri, V Marco, Prof and Scavonetto, Federica, MD and Schilling, Thomas, MD and Selmo, Gabriele, MD and Severgnini, Paolo, MD and Sprung, Juraj, Prof and Sundar, Sugantha, MD and Talmor, Daniel, MD and Treschan, Tanja, MD and Unzueta, Carmen, MD and Weingarten, Toby N, MD and Wolthuis, Esther K, MD and Wrigge, Hermann, Prof and Amato, Marcelo B P, Prof and Costa, Eduardo L V, MD and de Abreu, Marcelo Gama, Prof and Pelosi, Paolo, FERS and Schultz, Marcus J, Prof and PROVE Network Investigators
The lancet respiratory medicine, ISSN 2213-2600, 2016, Volume 4, Issue 4, pp. 272 - 280
Pulmonary/Respiratory | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Intraoperative Period | Postoperative Complications - etiology | Anesthesia, General - methods | Humans | Middle Aged | Positive-Pressure Respiration - adverse effects | Male | Anesthesia, General - adverse effects | Positive-Pressure Respiration - methods | Tidal Volume | Lung Diseases - etiology | Randomized Controlled Trials as Topic | Adult | Female | Aged | General anesthesia | Usage | Dosage and administration | Artificial respiration | Index Medicus | Life Sciences
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3. Full Text Protective versus Conventional Ventilation for Surgery A Systematic Review and Individual Patient Data Meta-analysis
by Serpa Neto, Ary and Hemmes, Sabrine N. T and Barbas, Carmen S. V and Beiderlinden, Martin and Biehl, Michelle and Binnekade, Jan M and Canet, Jaume and Fernandez-Bustamante, Ana and Futier, Emmanuel and Gajic, Ognjen and Hedenstierna, Göran and Hollmann, Markus W and Jaber, Samir and Kozian, Alf and Licker, Marc and Lin, Wen-Qian and Maslow, Anew D and Memtsoudis, Stavros G and Reis Miranda, Dinis and Moine, Pierre and Ng, Thomas and Paparella, Domenico and Putensen, Christian and Ranieri, Marco and Scavonetto, Federica and Schilling, Thomas and Schmid, Werner and Selmo, Gabriele and Severgnini, Paolo and Sprung, Juraj and Sundar, Sugantha and Talmor, Daniel and Treschan, Tanja and Unzueta, Carmen and Weingarten, Toby N and Wolthuis, Esther K and Wrigge, Hermann and Gama de Abreu, Marcelo and Pelosi, Paolo and Schultz, Marcus J and PROVE Network Investigators
Anesthesiology (Philadelphia), ISSN 0003-3022, 2015, Volume 123, Issue 1, pp. 66 - 78
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Respiration, Artificial - methods | Randomized Controlled Trials as Topic - methods | Humans | Positive-Pressure Respiration - methods | Statistics as Topic - methods | Positive-Pressure Respiration - standards | Respiration, Artificial - standards | Randomized Controlled Trials as Topic - standards | Tidal Volume - physiology | Index Medicus | Abridged Index Medicus | Life Sciences
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4. Full Text Pressure support ventilation and biphasic positive airway pressure improve oxygenation by redistribution of pulmonary blood flow
by Carvalho, Alysson R and Spieth, Peter M and Pelosi, Paolo and Beda, Alessandro and Lopes, Agnaldo J and Neykova, Boriana and Heller, Axel R and Koch, Thea and De Abreu, Marcelo Gama
Anesthesia and analgesia, ISSN 0003-2999, 2009, Volume 109, Issue 3, pp. 856 - 865
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Biological and medical sciences | Anesthesia | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Fluorescent Dyes - chemistry | Tomography, X-Ray Computed - methods | Positive-Pressure Respiration - methods | Tidal Volume | Pressure | Oxygen - metabolism | Microspheres | Animals | Swine | Female | Respiratory Mechanics | Lung - blood supply | Respiration | Acute Lung Injury | Cluster Analysis | Index Medicus | Abridged Index Medicus
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5. Full Text Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial
by Simonis, Fabienne D and Serpa Neto, Ary and Binnekade, Jan M and Braber, Annemarije and Bruin, Karina C. M and Determann, Rogier M and Goekoop, Geert-Jan and Heidt, Jeroen and Horn, Janneke and Innemee, Gerard and de Jonge, Evert and Juffermans, Nicole P and Spronk, Peter E and Steuten, Lotte M and Tuinman, Pieter Roel and de Wilde, Rob B.P and Vriends, Marijn and Gama de Abreu, Marcelo and Pelosi, Paolo and Schultz, Marcus J and Writing Grp PReVENT Investigators and Writing Group for the PReVENT Investigators
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 10/2018, Volume 320, Issue 18, pp. 1872 - 1880
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Respiratory Insufficiency - physiopathology | Intensive Care Units | Respiration, Artificial - methods | Hospital Mortality | Respiratory Distress Syndrome, Adult | Humans | Middle Aged | Male | Ventilator-Induced Lung Injury | Respiratory Insufficiency - therapy | Tidal Volume | Critical Illness - mortality | Outcome and Process Assessment (Health Care) | Respiration, Artificial - adverse effects | Critical Illness - therapy | Female | Aged | Ventilator Weaning | Acute respiratory distress syndrome | Clinical trials | Intensive care units | Services | Care and treatment | Analysis | Ventilators | Intensive care | Pneumothorax | Pneumonia | Mortality | Patients | Hospitals | Respiratory distress syndrome | Atelectasis | Volume | Ventilation | Strategy | Index Medicus | Abridged Index Medicus | Caring for the Critically Ill Patient | Online First | Research | Original Investigation
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6. Full Text Respiratory System Mechanics During Low Versus High Positive End-Expiratory Pressure in Open Abdominal Surgery: A Substudy of PROVHILO Randomized Controlled Trial
by D'Antini, Davide and Huhle, Robert and Herrmann, Jacob and Sulemanji, Demet S and Oto, Jun and Raimondo, Pasquale and Mirabella, Lucia and Hemmes, Sabrine N. T and Schultz, Marcus J and Pelosi, Paolo and Kaczka, David W and Vidal Melo, Marcos Francisco and Gama de Abreu, Marcelo and Cinnella, Gilda and PROtective VEntilation Network and European Soc Anaesthesiology and European Society of Anaesthesiology and the PROtective VEntilation Network
Anesthesia and analgesia, ISSN 0003-2999, 2018, Volume 126, Issue 1, pp. 143 - 149
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Postoperative Complications - physiopathology | Prospective Studies | Double-Blind Method | Humans | Middle Aged | Postoperative Complications - prevention & control | Male | Positive-Pressure Respiration - methods | Abdomen - surgery | Postoperative Complications - diagnosis | Female | Aged | Respiratory Mechanics - physiology | Index Medicus | Abridged Index Medicus
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7. Full Text Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial
by Bluth, Thomas and Serpa Neto, Ary and Schultz, Marcus J and Pelosi, Paolo and Gama de Abreu, Marcelo and Clinical Trial Network European and PROBESE Collaborative Grp and PROBESE Collaborative Group and Writing Committee for the PROBESE Collaborative Group of the PROtective VEntilation Network (PROVEnet) for the Clinical Trial Network of the European Society of Anaesthesiology
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 06/2019, Volume 321, Issue 23, pp. 2292 - 2305
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Body Mass Index | Pleural Diseases - etiology | Anesthesia, General | Pleural Diseases - prevention & control | Obesity - complications | Humans | Lung Diseases - prevention & control | Middle Aged | Postoperative Complications - prevention & control | Respiratory Insufficiency - etiology | Male | Treatment Outcome | Positive-Pressure Respiration - methods | Tidal Volume | Lung Diseases - etiology | Pulmonary Atelectasis - therapy | Respiratory Insufficiency - prevention & control | Intraoperative Care | Adult | Female | Surgical Procedures, Operative - adverse effects | Respiratory function | Body weight | Pleural effusion | Clinical trials | Maneuvers | Recruitment | Bronchospasm | Hypoxemia | Atelectasis | Surgery | Anesthesia | Alveoli | Desaturation | Respiratory therapy | Edema | Pneumothorax | Complications | Low level | Pressure | Patients | Pneumonitis | Respiratory distress syndrome | Body mass | Ventilation | Adults | Index Medicus | Abridged Index Medicus | Caring for the Critically Ill Patient | Online First | Research | Original Investigation
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8. Full Text Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts
by Serpa Neto, Ary and Deliberato, Rodrigo Octavio and Johnson, Alistair E. W and Bos, Lieuwe D and Amorim, Pedro and Pereira, Silvio Moreto and Cazati, Denise Carnieli and Cordioli, Ricardo L and Correa, Thiago Domingos and Pollard, Tom J and Schettino, Guilherme P. P and Timenetsky, Karina T and Celi, Leo A and Pelosi, Paolo and Gama de Abreu, Marcelo and Schultz, Marcus J and PROVE Network Investigators and for the PROVE Network Investigators
Intensive care medicine, ISSN 0342-4642, 2018, Volume 44, Issue 11, pp. 1914 - 1922
Mechanical power | Ventilator-induced lung injury | Critically ill | Mechanical ventilation | Mortality | Intensive care unit | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Usage | Care and treatment | Netherlands | Demographic aspects | Research | Artificial respiration | Brazil | Analysis | Confidence intervals | Ventilators | Lungs | Data processing | Ventilation | Patients | Index Medicus
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9. Full Text The effects of salbutamol on epithelial ion channels depend on the etiology of acute respiratory distress syndrome but not the route of administration
by Uhlig, Christopher and Silva, Pedro L and Ornellas, Débora and Santos, Raquel S and Miranda, Paulo J and Spieth, Peter M and Kiss, Thomas and Kasper, Michael and Wiedemann, Bärbel and Koch, Thea and Morales, Marcelo M and Pelosi, Paolo and De Abreu, Marcelo G and Rocco, Patricia R.M
Respiratory research, ISSN 1465-9921, 02/2014, Volume 15, Issue 1, pp. 56 - 56
Acute respiratory distress syndrome | Edema | Elastance | Salbutamol | Epithelial sodium channel | Alveolar epithelial cells | Life Sciences & Biomedicine | Respiratory System | Science & Technology | Injections, Spinal | Ion Channels - biosynthesis | Prospective Studies | Respiratory Mucosa - drug effects | Rats, Wistar | Rats | Male | Treatment Outcome | Random Allocation | Respiratory Distress Syndrome, Adult - drug therapy | Respiratory Distress Syndrome, Adult - metabolism | Respiratory Distress Syndrome, Adult - etiology | Administration, Intravenous | Animals | Albuterol - administration & dosage | Respiratory Mucosa - metabolism | Home care services industry | Gene expression | Analysis | Genes | Home care services | Studies | Electrocardiography | Medical research | Respiratory distress syndrome | Rodents | Index Medicus | Research
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10. Full Text Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study
by Neto, Ary Serpa, Dr and Barbas, Carmen S V, MD and Simonis, Fabienne D, MD and Artigas-Raventós, Antonio, MD and Canet, Jaume, MD and Determann, Rogier M, MD and Anstey, James, MD and Hedenstierna, Goran, MD and Hemmes, Sabrine N T, MD and Hermans, Greet, MD and Hiesmayr, Michael, MD and Hollmann, Markus W, MD and Jaber, Samir, MD and Martin-Loeches, Ignacio, MD and Mills, Gary H, MD and Pearse, Rupert M, MD and Putensen, Christian, MD and Schmid, Werner, MD and Severgnini, Paolo, MD and Smith, Roger, MD and Treschan, Tanja A, MD and Tschernko, Edda M, MD and Melo, Marcos F V, MD and Wrigge, Hermann, MD and de Abreu, Marcelo Gama, MD and Pelosi, Paolo, MD and Schultz, Marcus J, MD and PRoVENT and PROVE Network investigators and PROVE Network Investigator and PRoVENT Network Investigator
The lancet respiratory medicine, ISSN 2213-2600, 2016, Volume 4, Issue 11, pp. 882 - 893
Pulmonary/Respiratory | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Prevalence | Prospective Studies | Respiration, Artificial - methods | Hospital Mortality | Humans | Middle Aged | Risk Factors | Positive-Pressure Respiration - adverse effects | Intensive Care Units - statistics & numerical data | Male | Positive-Pressure Respiration - methods | Tidal Volume | Respiratory Distress Syndrome, Adult - etiology | Critical Illness - epidemiology | Respiration, Artificial - adverse effects | Critical Illness - therapy | Female | Aged | Respiratory Distress Syndrome, Adult - epidemiology | Acute respiratory distress syndrome | Intensive care units | Ventilators | Usage | Research | Management | Epidemiology | Risk factors | Prevention | Physiological aspects | Artificial respiration | Index Medicus
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