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1. Full Text Correction: Vaccine Strain-Specificity of Protective HLA-Restricted Class 1 P. falciparum Epitopes
by Sedegah, Martha and Peters, Bjoern and Hollingdale, Michael R and Ganeshan, Harini D and Huang, Jun and Farooq, Fouzia and Belmonte, Maria N and Belmonte, Arnel D and Limbach, Keith J and Diggs, Carter and Soisson, Lorraine and Chuang, Ilin and Villasante, Eileen D
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 12, p. e0168952
[This corrects the article DOI: 10.1371/journal.pone.0163026.]. 
Histocompatibility antigen HLA | Epitopes | Lymphocytes | Deoxyribonucleic acid--DNA | Erythrocytes | Deoxyribonucleic acid | DNA
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2. Full Text Vaccine strain-specificity of protective HLA-restricted class 1 P. falciparum epitopes
by Sedegah, Martha and Peters, Bjoern and Hollingdale, Michael R and Ganeshan, Harini D and Huang, Jun and Farooq, Fouzia and Belmonte, Maria N and Belmonte, Arnel D and Limbach, Keith J and Diggs, Carter and Soisson, Lorraine and Chuang, Ilin and Villasante, Eileen D
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0163026
A DNA prime/adenovirus boost malaria vaccine encoding Plasmodium falciparum strain 3D7 CSP and AMA1 elicited sterile clinical protection associated with CD8+ T... 
IMMUNIZATION | PROTEIN | ORIENTATION | MULTIDISCIPLINARY SCIENCES | CLASS-I SUPERTYPES | MALARIA | PREDICTIONS | T-CELL RECEPTOR | BINDING | AFFINITIES | ALTERED PEPTIDE LIGANDS | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | HLA-B Antigens - immunology | HLA Antigens - immunology | Membrane Proteins - immunology | Plasmodium falciparum - immunology | Epitopes - immunology | Flow Cytometry | CD8-Positive T-Lymphocytes - drug effects | Malaria Vaccines - immunology | Malaria, Falciparum - immunology | CD8-Positive T-Lymphocytes - immunology | Interferon-gamma - pharmacology | Protozoan Proteins - immunology | Plasmodium falciparum | Peptides | Malaria | Malaria vaccine | Amino acids | Interferon | Vaccines | Comparative analysis | Biological response modifiers | T cells | Antigenic determinants | Flow cytometry | Military medicine | CD8 antigen | Erythrocytes | Clinical trials | Lymphocytes T | Infections | Assaying | Proteins | T-cell receptor | Lymphocytes | Recall | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Vector-borne diseases | Medical research | Antigens | T cell receptors | Epitopes | Strain | Medicine | Cytometry | Major histocompatibility complex | Acids | Adenoviruses | γ-Interferon | Histocompatibility antigen HLA | Deoxyribonucleic acid | DNA
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3. Full Text DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity
by Chuang, I and Sedegah, M and Cicatelli, S and Spring, M and Polhemus, M and Tamminga, C and Patterson, N and Guerrero, M and Bennett, J.W and McGrath, S and Ganeshan, H and Belmonte, M and Farooq, F and Abot, E and Banania, J.G and Huang, J and Newcomer, R and Rein, L and Litilit, D and Richie, N.O and Wood, C and Murphy, J and Sauerwein, R.W and Hermsen, C.C and McCoy, A.J and Kamau, E and Cummings, J and Komisar, J and Sutamihardja, A and Shi, M and Epstein, J.E and Maiolatesi, S and Tosh, D and Limbach, K and Angov, E and Bergmann-Leitner, E and Bruder, J.T and Doolan, D.L and King, C.R and Carucci, D and Dutta, S and Soisson, L and Diggs, C and Hollingdale, M.R and Ockenhouse, C.F and Richie, T.L
PLoS One, ISSN 1932-6203, 2013, Volume 8, Issue 2, p. e55571
BACKGROUND: Gene-based vaccination using prime/boost regimens protects animals and humans against malaria, inducing cell-mediated responses that in animal... 
APICAL MEMBRANE ANTIGEN-1 | SPOROZOITE INOCULATION | VIRUS ANKARA | IMMUNIZATION | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | CIRCUMSPOROZOITE PROTEIN | DOUBLE-BLIND | NAIVE ADULTS | CYTOTOXIC T-LYMPHOCYTES | PHASE 2A TRIAL | Vaccines, DNA - genetics | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | Middle Aged | Vaccines, DNA - immunology | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Young Adult | Malaria Vaccines - adverse effects | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Adult | Female | Antigens, Protozoan - genetics | Malaria Vaccines - therapeutic use | Membrane Proteins - genetics | Adenoviruses, Human - immunology | Membrane Proteins - immunology | Vaccines, DNA - therapeutic use | Malaria, Falciparum - parasitology | Interferon-gamma - immunology | Vaccines, DNA - adverse effects | Adolescent | Malaria, Falciparum - immunology | Adenoviruses, Human - genetics | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Antigens | Wildlife conservation | Malaria | Liver | Vaccination | Malaria vaccine | Vaccines | T cells | Plasmodium falciparum | Advertising executives | Mosquitoes | Control | Analysis | Adenoviruses | DNA | Bites and stings | Genetic aspects | Health aspects | Enzyme-linked immunosorbent assay | Flow cytometry | Animal models | Goats | CD8 antigen | Antibodies | Leukocytes (mononuclear) | Lymphocytes T | Parasites | Aquatic insects | Immunity | Immunity (cell-mediated) | Replicating | Acquired immune deficiency syndrome--AIDS | Sporozoites | Peripheral blood mononuclear cells | Deoxyribonucleic acid--DNA | Circumsporozoite protein | Expression vectors | Vector-borne diseases | Medical research | Immunization | Statistical analysis | Diarrhea | Membrane proteins | Cytometry | Plasmids | γ-Interferon | Interferon | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS
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4. Full Text Sterile immunity to malaria after DNA prime/adenovirus boost immunization is associated with effector memory CD8+T cells targeting ama1 class I epitopes
by Sedegah, Martha and Hollingdale, Michael R and Farooq, Fouzia and Ganeshan, Harini and Belmonte, Maria and Kim, Yohan and Peters, Bjoern and Sette, Alessandro and Huang, Jun and McGrath, Shannon and Abot, Esteban and Limbach, Keith and Shi, Meng and Soisson, Lorraine and Diggs, Carter and Chuang, Ilin and Tamminga, Cindy and Epstein, Judith E and Villasante, Eileen and Richie, Thomas L
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e106241
Background: Fifteen volunteers were immunized with three doses of plasmid DNA encoding P. falciparum circumsporozoite protein (CSP) and apical membrane... 
APICAL MEMBRANE ANTIGEN-1 | RESPONSES | IMMUNOGENICITY | PROTEIN | PROTECTION | LIVER STAGES | SAFETY | MULTIDISCIPLINARY SCIENCES | VACCINE | CANDIDATE | CD8(+) T-CELLS | Antigens, Protozoan - immunology | DNA - immunology | Humans | Malaria, Falciparum - pathology | DNA - administration & dosage | Membrane Proteins - immunology | Plasmodium falciparum - immunology | Epitopes - immunology | Membrane Proteins - administration & dosage | Malaria, Falciparum - parasitology | Interleukin-2 - immunology | Malaria Vaccines - administration & dosage | Interferon-gamma - immunology | Antigens, Protozoan - administration & dosage | Malaria Vaccines - immunology | Malaria, Falciparum - immunology | Tumor Necrosis Factor-alpha - immunology | Plasmodium falciparum - pathogenicity | Adult | Immunologic Memory | Protozoan Proteins - administration & dosage | Adenoviridae - immunology | CD8-Positive T-Lymphocytes - immunology | Protozoan Proteins - immunology | Infection | Plasmodium falciparum | Immunization | Malaria | Adenoviruses | DNA | Interferon | T cells | Health aspects | Antigenic determinants | CD8 antigen | Liver | Effector cells | Lymphocytes T | Infections | Vaccines | Immunity | Proteins | Immunology | Interleukin 2 | Lymphocytes | Plasmid DNA | Volunteers | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Circumsporozoite protein | Vector-borne diseases | Antigens | Medical research | Immunological memory | Memory cells | Priming | Epitopes | Tumor necrosis factor-α | Vectors (Biology) | Membrane proteins | Plasmids | γ-Interferon | Comparative analysis | Deoxyribonucleic acid
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5. Full Text Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: Safety, immunogenicity and protective efficacy of the CSP component
by Tamminga, Cindy and Sedegah, Martha and Regis, David and Chuang, Ilin and Epstein, Judith E and Spring, Michele and Mendoza-Silveiras, Jose and McGrath, Shannon and Maiolatesi, Santina and Reyes, Sharina and Steinbeiss, Victoria and Fedders, Charlotte and Smith, Kathryn and House, Brent and Ganeshan, Harini and Lejano, Jennylynn and Abot, Esteban and Banania, Glenna J and Sayo, Renato and Farooq, Fouzia and Belmonte, Maria and Murphy, Jittawadee and Komisar, Jack and Williams, Jackie and Shi, Meng and Brambilla, Donald and Manohar, Nalini and Richie, Nancy O and Wood, Chloe and Limbach, Keith and Patterson, Noelle B and Bruder, Joseph T and Doolan, Denise L and King, C. Richter and Diggs, Carter and Soisson, Lorraine and Carucci, Daniel and Levine, Gail and Dutta, Sheetij and Hollingdale, Michael R and Ockenhouse, Christian F and Richie, Thomas L
PLoS ONE, ISSN 1932-6203, 10/2011, Volume 6, Issue 10, p. e25868
Background: A protective malaria vaccine will likely need to elicit both cell-mediated and antibody responses. As adenovirus vaccine vectors induce both these... 
APICAL MEMBRANE ANTIGEN-1 | NATURAL IMMUNE-RESPONSES | T-CELL RESPONSES | RHESUS-MONKEYS | PLASMODIUM-FALCIPARUM | MULTIDISCIPLINARY SCIENCES | CIRCUMSPOROZOITE PROTEIN | SEQUENTIAL IMMUNIZATION | NAIVE ADULTS | CANDIDATE MALARIA VACCINE | PHASE 2A TRIAL | Protozoan Proteins - adverse effects | Antigens, Protozoan - immunology | Dose-Response Relationship, Immunologic | Humans | Membrane Proteins - adverse effects | Middle Aged | Male | Plasmodium falciparum - cytology | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Sporozoites - immunology | Young Adult | Malaria Vaccines - adverse effects | Malaria Vaccines - immunology | Adenoviridae - genetics | Adult | Female | Antigens, Protozoan - adverse effects | Antigens, Protozoan - genetics | Gene Expression | Membrane Proteins - genetics | Membrane Proteins - immunology | Genetic Vectors - genetics | Adolescent | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Antigens | Plasmodium falciparum | Advertising executives | Malaria | Adenoviruses | Malaria vaccine | Vaccines | Drug therapy | Vector-borne diseases | Immunization | Goats | CD8 antigen | Antibodies | Dosage | Aquatic insects | CD4 antigen | Mosquitoes | Immunogenicity | Coding | Plasmids | Infectivity | Adults | Safety | Enzyme-linked immunosorbent assay | Circumsporozoite protein | Viral infections | Expression vectors
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6. Full Text Adenovirus 5-vectored p. falciparum vaccine expressing CSP and ama1. part a: Safety and immunogenicity in seronegative adults
by Sedegah, Martha and Tamminga, Cindy and McGrath, Shannon and House, Brent and Ganeshan, Harini and Lejano, Jennylynn and Abot, Esteban and Banania, Glenna J and Sayo, Renato and Farooq, Fouzia and Belmonte, Maria and Manohar, Nalini and Richie, Nancy O and Wood, Chloe and Long, Carole A and Regis, David and Williams, Francis T and Shi, Meng and Chuang, Ilin and Spring, Michele and Epstein, Judith E and Mendoza-Silveiras, Jose and Limbach, Keith and Patterson, Noelle B and Bruder, Joseph T and Doolan, Denise L and King, C.Richter and Soisson, Lorraine and Diggs, Carter and Carucci, Daniel and Dutta, Sheetij and Hollingdale, Michael R and Ockenhouse, Christian F and Richie, Thomas L
PLoS ONE, ISSN 1932-6203, 10/2011, Volume 6, Issue 10, p. e24586
Background: Models of immunity to malaria indicate the importance of CD8+ T cell responses for targeting intrahepatic stages and antibodies for targeting... 
APICAL MEMBRANE ANTIGEN-1 | NATURAL IMMUNE-RESPONSES | PROTECTIVE IMMUNITY | MULTIDISCIPLINARY SCIENCES | CIRCUMSPOROZOITE PROTEIN | T-CELL EPITOPES | PRIME-BOOST REGIMENS | PLASMODIUM-BERGHEI SPOROZOITES | PHASE I/IIA SAFETY | VIRAL VECTORS | CANDIDATE MALARIA VACCINE | Protozoan Proteins - adverse effects | Antigens, Protozoan - immunology | Dose-Response Relationship, Immunologic | Immunity, Humoral - immunology | Humans | Membrane Proteins - adverse effects | Middle Aged | Male | Interferon-gamma - metabolism | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Malaria Vaccines - chemistry | CD4-Positive T-Lymphocytes - immunology | Young Adult | Malaria Vaccines - adverse effects | Peptide Fragments - immunology | Malaria Vaccines - immunology | Adenoviridae - genetics | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Protozoan Proteins - chemistry | Antigens, Protozoan - adverse effects | Antigens, Protozoan - genetics | Gene Expression | Antigens, Protozoan - chemistry | Membrane Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Membrane Proteins - immunology | Genetic Vectors - genetics | Immunity, Cellular - immunology | Membrane Proteins - chemistry | Adolescent | CD8-Positive T-Lymphocytes - immunology | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Plasmodium falciparum | Antigens | Safety and security measures | Malaria | Adenoviruses | Malaria vaccine | Vaccines | T cells | Military medicine | Goats | CD8 antigen | Fluorescence | Antibodies | Lymphocytes T | Parasites | Immunity | Blood | Proteins | Interleukin 2 | Lymphocytes | Armed forces | Safety | Volunteers | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Circumsporozoite protein | Vector-borne diseases | Medical research | Dendritic cells | Tumor necrosis factor-α | Membrane proteins | CD4 antigen | Medicine | Immunogenicity | γ-Interferon | Interferon | Adults | Deoxyribonucleic acid | DNA
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7. Full Text Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP)
by Sedegah, Martha and Kim, Yohan and Ganeshan, Harini and Huang, Jun and Belmonte, Maria and Abot, Esteban and Banania, Jo Glenna and Farooq, Fouzia and McGrath, Shannon and Peters, Bjoern and Sette, Alessandro and Soisson, Lorraine and Diggs, Carter and Doolan, Denise L and Tamminga, Cindy and Villasante, Eileen and Hollingdale, Michael R and Richie, Thomas L
Malaria Journal, ISSN 1475-2875, 2013, Volume 12, Issue 1, pp. 185 - 185
Background: Plasmodium falciparum circumsporozoite protein (CSP) is a leading malaria vaccine candidate antigen, known to elicit protective antibody responses... 
Flow cytometry | Malaria | NetMHC | Epitope mapping | Vaccine | Class I restriction | Localization | Circumsporozoite protein | ELISpot | INFECTIOUS DISEASES | HEPATOCYTES | SPECIFICITY | PEPTIDE-BINDING | ANTIGENS | HLA-A | MALARIA VACCINE | TROPICAL MEDICINE | RESPONSES | IMMUNOGENICITY | SUPERTYPES | I ALLELE PROMISCUITY | PARASITOLOGY | Epitope Mapping | Humans | Computational Biology | Histocompatibility Antigens Class I - immunology | Clinical Trials as Topic | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Human Experimentation | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Epitopes, T-Lymphocyte - immunology | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Advertising executives | Plasmodium falciparum | Immunity | Malaria vaccine | Proteins | Immunology | Vaccines
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8. Full Text Measurement of ex vivo ELISpot interferon-gamma recall responses to Plasmodium falciparum AMA1 and CSP in Ghanaian adults with natural exposure to malaria
by Ganeshan, Harini and Kusi, Kwadwo A and Anum, Dorothy and Hollingdale, Michael R and Peters, Bjoern and Kim, Yohan and Tetteh, John K. A and Ofori, Michael F and Gyan, Ben A and Koram, Kwadwo A and Huang, Jun and Belmonte, Maria and Banania, Jo Glenna and Dodoo, Daniel and Villasante, Eileen and Sedegah, Martha
Malaria Journal, ISSN 1475-2875, 02/2016, Volume 15, Issue 1, p. 55
Background: Malaria eradication requires a concerted approach involving all available control tools, and an effective vaccine would complement these efforts.... 
CSP | AMA1 | IFN-γ | Apical membrane antigen-1 | Natural transmission | Ghana | HLA | T cells | Ex vivo ELISpot | Peptide | Circumsporozoite protein | Class I-restricted epitope | INFECTIOUS DISEASES | VACCINE | T-CELL EPITOPES | SPOROZOITES | HLA-A | IDENTIFICATION | TROPICAL MEDICINE | IFN-gamma | I ALLELE PROMISCUITY | ACQUIRED IMMUNE-RESPONSES | LIVER-STAGE ANTIGEN-1 | PARASITOLOGY | Young Adult | Humans | Malaria - immunology | Computational Biology | Adult | Female | Male | Enzyme-Linked Immunospot Assay | Interferon-gamma - metabolism | Plasmodium falciparum - immunology | Malaria - metabolism | Protozoan Proteins - immunology | Complications and side effects | Plasmodium falciparum | Care and treatment | Malaria | Physiological aspects | Research | Public health
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9. Full Text Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein
by Sedegah, Martha and Kim, Yohan and Peters, Bjoern and McGrath, Shannon and Ganeshan, Harini and Lejano, Jennylynn and Abot, Esteban and Banania, Glenna and Belmonte, Maria and Sayo, Renato and Farooq, Fouzia and Doolan, Denise L and Regis, David and Tamminga, Cindy and Chuang, Ilin and Bruder, Joseph T and King, C. Richter and Ockenhouse, Christian F and Faber, Bart and Remarque, Edmond and Hollingdale, Michael R and Richie, Thomas L and Sette, Alessandro
Malaria Journal, ISSN 1475-2875, 2010, Volume 9, Issue 1, pp. 241 - 241
Background: Plasmodium falciparum apical membrane antigen-1 (AMA1) is a leading malaria vaccine candidate antigen that is expressed by sporozoite, liver and... 
APICAL MEMBRANE ANTIGEN-1 | NATURAL IMMUNE-RESPONSES | INFECTIOUS DISEASES | CLINICAL-TRIAL | CIRCUMSPOROZOITE PROTEIN | CLASS-I SUPERTYPES | TROPICAL MEDICINE | BLOOD-STAGE VACCINE | MALARIA VACCINE CANDIDATE | GENETIC DIVERSITY | INVASION | PROTECTIVE ANTIGEN | PARASITOLOGY | Epitope Mapping | Antigens, Protozoan - immunology | Humans | Interferon-gamma - secretion | Membrane Proteins - immunology | Human Experimentation | Malaria Vaccines - immunology | Adult | Adenoviruses, Human - genetics | Epitopes, T-Lymphocyte - immunology | CD8-Positive T-Lymphocytes - immunology | Genetic Vectors | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Prevention | Major histocompatibility complex | Malaria | Malaria vaccine | Physiological aspects | Causes of | Genetic aspects | Research | T cells | Health aspects | Peptides | CD8 antigen | Liver | Clinical trials | Lymphocytes T | Vaccines | Parasites | AmA1 protein | Blood | Human populations | Proteins | Lymphocytes | Peripheral blood mononuclear cells | Localization | Protection | Public health | Enzyme-linked immunosorbent assay | Vector-borne diseases | Antigens | Enzymes | Human diseases | Immunoglobulins | Epitopes | Pools | Disease control | Depletion | Algorithms | Immunogenicity | Adenoviruses | Alleles | Frequency | Interferon | Recombinants | Histocompatibility antigen HLA
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10. Full Text Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: Safety, tolerability, protective efficacy and humoral immunogenicity
by Hickey, Bradley W and Lumsden, Joanne M and Reyes, Sharina and Sedegah, Martha and Hollingdale, Michael R and Freilich, Daniel A and Luke, Thomas C and Charoenvit, Yupin and Goh, Lucy M and Berzins, Mara P and Bebris, Lolita and Sacci, John B and De La Vega, Patricia and Wang, Ruobing and Ganeshan, Harini and Abot, Esteban N and Carucci, Daniel J and Doolan, Denise L and Brice, Gary T and Kumar, Anita and Aguiar, Joao and Nutman, Thomas B and Leitman, Susan F and Hoffman, Stephen L and Epstein, Judith E and Richie, Thomas L
Malaria Journal, ISSN 1475-2875, 07/2016, Volume 15, Issue 1, p. 377
Background: In this phase 1 clinical trial, healthy adult, malaria-naive subjects were immunized with radiation-attenuated Plasmodium falciparum sporozoites... 
DIRECT VENOUS INOCULATION | INFECTIOUS DISEASES | VOLUNTEERS | CIRCUMSPOROZOITE PROTEIN | VACCINE | ANTIGENS | TROPICAL MEDICINE | HUMAN MALARIA INFECTION | IMMUNE-RESPONSES | SURFACE | CELL | T-LYMPHOCYTE RESPONSES | PARASITOLOGY | Malaria, Falciparum - prevention & control | Humans | Middle Aged | Sporozoites - radiation effects | Male | Plasmodium falciparum - immunology | Sporozoites - immunology | Plasmodium falciparum - radiation effects | Drug-Related Side Effects and Adverse Reactions - epidemiology | Drug-Related Side Effects and Adverse Reactions - pathology | Young Adult | Culicidae - physiology | Antibodies, Protozoan - blood | Vaccines, Attenuated - immunology | Animals | Malaria Vaccines - administration & dosage | Malaria Vaccines - adverse effects | Vaccines, Attenuated - administration & dosage | Adolescent | Malaria Vaccines - immunology | Adult | Insect Bites and Stings | Vaccines, Attenuated - adverse effects | Malaria
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