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Journal of the American Society of Nephrology, ISSN 1046-6673, 07/2019, Volume 30, Issue 9, pp. ASN.2019010007 - 1745
BACKGROUNDSurrogate end points are needed to assess whether treatments are effective in the early stages of CKD. GFR decline leads to kidney failure, but... 
Index Medicus
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 07/2019, Volume 30, Issue 9, pp. ASN.2019010008 - 1755
BACKGROUNDDecline in eGFR is a biologically plausible surrogate end point for the progression of CKD in clinical trials. However, it must first be tested to... 
Index Medicus
Journal Article
Current Opinion in Nephrology and Hypertension, ISSN 1062-4821, 08/2019
PURPOSE OF REVIEWChronic kidney disease is a global health problem with few effective therapies available that slow the progression to end-stage renal disease.... 
Index Medicus
Journal Article
Kidney International Reports, ISSN 2468-0249, 08/2019, Volume 4, Issue 8, pp. 1170 - 1174
Journal Article
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, ISSN 1046-6673, 08/2019, Volume 30, Issue 8, pp. 1513 - 1521
Background The formation and growth of cysts in kidneys, and often liver, in autosomal dominant polycystic kidney disease (ADPKD) cause progressive increases... 
CONSORTIUM | UROLOGY & NEPHROLOGY | DIPAK 1 | PROGRESSION | LANREOTIDE | Index Medicus
Journal Article
Clinical Nutrition, ISSN 0261-5614, 07/2019
BACKGROUND & AIMSUrinary creatinine excretion reflecting endogenous creatinine synthesis rate (CSR) is an established measure of muscle mass in the general... 
Index Medicus
Journal Article
Kidney International, ISSN 0085-2538, 07/2019, Volume 96, Issue 1, pp. 159 - 169
In the TEMPO 3:4 Trial, treatment with tolvaptan, a vasopressin V2 receptor antagonist, slowed the increase in total kidney volume and decline in estimated... 
copeptin | tolvaptan | ADPKD | AVP | polycystic kidney disease | vasopressin | POPULATION | DISORDERS | MODEL | FUNCTION DECLINE | OSMOLALITY | URINE | UROLOGY & NEPHROLOGY | SURROGATE MARKER | RENAL CONCENTRATING CAPACITY | CYST GROWTH
Journal Article
Journal of Cachexia, Sarcopenia and Muscle, ISSN 2190-5991, 06/2019, Volume 10, Issue 3, pp. 621 - 629
Journal Article
Kidney International Reports, ISSN 2468-0249, 06/2019, Volume 4, Issue 6, pp. 833 - 841
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst formation and variable renal function decline that frequently leads... 
urinary biomarkers | chronic renal dysfunction | tissue inhibitor of metalloproteinases-2 | ADPKD | disease severity | insulin-like growth factor–binding protein 7
Journal Article
JOURNAL OF CLINICAL MEDICINE, ISSN 2077-0383, 06/2019, Volume 8, Issue 6, p. 779
Sodium glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of heart and kidney failure in patients with type 2 diabetes, possibly due to diuretic... 
heart failure | MEDICINE, GENERAL & INTERNAL | SGLT2 inhibitor | dapagliflozin | diabetic nephropathy
Journal Article
European Journal of Preventive Cardiology, ISSN 2047-4873, 6/2019, Volume 26, Issue 9, pp. 905 - 916
Aims To investigate prospectively the association of body fat percentage (BF%) estimates using various equations from bioelectrical impedance analysis (BIA)... 
cardiovascular disease | bioelectrical impedance analysis | Body fat | waist circumference | BMI | CVD Risk Factors
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 06/2019, Volume 34, Issue Supplement_1
Journal Article
by Wuttke, Matthias and Li, Yong and Li, Man and Sieber, Karsten B and Feitosa, Mary F and Gorski, Mathias and Tin, Adrienne and Wang, Lihua and Chu, Audrey Y and Hoppmann, Anselm and Kirsten, Holger and Giri, Ayush and Chai, Jin-Fang and Sveinbjornsson, Gardar and Tayo, Bamidele O and Nutile, Teresa and Fuchsberger, Christian and Marten, Jonathan and Cocca, Massimiliano and Ghasemi, Sahar and Xu, Yizhe and Horn, Katrin and Noce, Damia and van der Most, Peter J and Sedaghat, Sanaz and Yu, Zhi and Akiyama, Masato and Afaq, Saima and Ahluwalia, Tarunveer S and Almgren, Peter and Amin, Najaf and Ärnlöv, Johan and Bakker, Stephan J. L and Bansal, Nisha and Baptista, Daniela and Bergmann, Sven and Biggs, Mary L and Biino, Ginevra and Boehnke, Michael and Boerwinkle, Eric and Boissel, Mathilde and Bottinger, Erwin P and Boutin, Thibaud S and Brenner, Hermann and Brumat, Marco and Burkhardt, Ralph and Butterworth, Adam S and Campana, Eric and Campbell, Archie and Campbell, Harry and Canouil, Mickaël and Carroll, Robert J and Catamo, Eulalia and Chambers, John C and Chee, Miao-Ling and Chee, Miao-Li and Chen, Xu and Cheng, Ching-Yu and Cheng, Yurong and Christensen, Kaare and Cifkova, Renata and Ciullo, Marina and Concas, Maria Pina and Cook, James P and Coresh, Josef and Corre, Tanguy and Sala, Cinzia Felicita and Cusi, Daniele and Danesh, John and Daw, E. Warwick and de Borst, Martin H and De Grandi, Alessandro and de Mutsert, Renée and de Vries, Aiko P. J and Degenhardt, Frauke and Delgado, Graciela and Demirkan, Ayse and Di Angelantonio, Emanuele and Dittrich, Katalin and Divers, Jasmin and Dorajoo, Rajkumar and Eckardt, Kai-Uwe and Ehret, Georg and Elliott, Paul and Endlich, Karlhans and Evans, Michele K and Felix, Janine F and Foo, Valencia Hui Xian and Franco, Oscar H and Franke, Andre and Freedman, Barry I and Freitag-Wolf, Sandra and Friedlander, Yechiel and Froguel, Philippe and Gansevoort, Ron T and Gao, He and Gasparini, Paolo and Gaziano, J. Michael and Giedraitis, Vilmantas and Gieger, Christian and ... and V. A. Million Veteran Program and Lifelines Cohort Study
Nature Genetics, ISSN 1061-4036, 06/2019, Volume 51, Issue 6, pp. 957 - 972
Journal Article
Frontiers in Neurology, ISSN 1664-2295, 2019, Volume 10, Issue MAY, pp. 497 - 497
Long-term changes in (bio)markers for cognitive frailty are not well characterized. Therefore, our aim is to explore (bio)marker trajectories in adults who... 
Biomarkers | Cognitive frailty | Trajectories | Doetinchem Cohort Study | Markers | Body mass index | Analysis | Cognition | markers | cognitive frailty | biomarkers | trajectories
Journal Article