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PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, pp. e33258 - e33258
Acute tubular necrosis (ATN) caused by ischemia/reperfusion (I/R) during renal transplantation delays allograft function. Identification of factors that... 
ACUTE KIDNEY INJURY | ISCHEMIA/REPERFUSION INJURY | ACTIVATION | ERYTHROPOIETIN | EPITHELIAL-CELLS | FACTOR-1-ALPHA | DISEASE | BIOLOGY | GENE-EXPRESSION | NITRIC-OXIDE | LOW-OXYGEN TENSION | Immunohistochemistry | Oxygen - pharmacology | Transcription, Genetic - drug effects | Kidney Tubular Necrosis, Acute - complications | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Male | Transplantation, Homologous | Young Adult | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Adult | Female | Reperfusion Injury - complications | Proto-Oncogene Proteins c-akt - metabolism | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Cell Survival - drug effects | Cell Hypoxia - drug effects | Kidney Tubules, Proximal - pathology | Reperfusion Injury - pathology | Rats | Epithelial Cells - pathology | Kidney Transplantation | Gene Expression Regulation - drug effects | Animals | Signal Transduction - drug effects | Epithelial Cells - enzymology | Kidney Tubules, Proximal - metabolism | Aged | Kidney Tubular Necrosis, Acute - pathology | Kidney Tubules, Proximal - drug effects | Kidneys | Ischemia | Cell death | Analysis | Genes | Transplantation | Gene expression | Hypoxia-inducible factor 1 | Nephrology | Cell survival | Renal function | Transplants & implants | Interference | Tubules | Proximal tubules | Epithelium | Immunology | Reperfusion | Metabolites | Rodents | Hypoxia | Kidney diseases | Oxygen tension | Vascular endothelial growth factor | Cancer | Kidney transplantation | Index Medicus
Journal Article
JOURNAL OF NEUROLOGY, ISSN 0340-5354, 07/2016, Volume 263, Issue 7, pp. 1390 - 1400
Journal Article
Journal of Neurology, ISSN 0340-5354, 7/2016, Volume 263, Issue 7, pp. 1390 - 1400
Huntington’s disease (HD) is a neurodegenerative disease for which there is no curative treatment available. Given that the endocannabinoid system is involved... 
Neurology | Neurosciences | Medicine & Public Health | Sativex | Clinical trial | Huntington’s disease | Cannabinoid | Neuroradiology
Journal Article
The Journal of cell biology, ISSN 0021-9525, 03/2017, Volume 216, Issue 3, pp. 835 - 847
Vascular cell adhesion molecule 1 (VCAM-1) is an adhesion molecule assigned to the activated endothelium mediating immune cells adhesion and extravasation.... 
NUCLEUS PULPOSUS | BREAST-CANCER | ADHESION MOLECULE-1 | CANCER CELLS | GENE-EXPRESSION | TUMOR | IKK-ALPHA | TNF-ALPHA | HYPOXIA | HIPPEL-LINDAU PROTEIN | CELL BIOLOGY | von Hippel-Lindau Disease - immunology | Kidney Neoplasms - genetics | Humans | Kidney Neoplasms - immunology | NF-kappa B - immunology | Carcinoma, Renal Cell - genetics | Mutation - immunology | Carcinoma, Renal Cell - immunology | Signal Transduction - immunology | Vascular Cell Adhesion Molecule-1 - genetics | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Gene Expression Regulation, Neoplastic - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - immunology | Vascular Cell Adhesion Molecule-1 - immunology | Basic Helix-Loop-Helix Transcription Factors - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Gene Expression Regulation, Neoplastic - immunology | Integrin alpha4beta1 - genetics | Signal Transduction - genetics | von Hippel-Lindau Disease - genetics | Mutation - genetics | Integrin alpha4beta1 - immunology | Von Hippel-Lindau Tumor Suppressor Protein - immunology | NF-kappa B - genetics | Cell Line, Tumor | Transcription, Genetic - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Biomarkers, Tumor - genetics | Transcription, Genetic - genetics | Biomarkers, Tumor - immunology | Index Medicus
Journal Article
International Journal of Molecular Sciences, ISSN 1422-0067, 04/2019, Volume 20, Issue 8, p. 1901
Clear cell renal cell carcinoma (ccRCC) is the seventh most frequently diagnosed tumor in adults in Europe and represents approximately 2.5% of cancer deaths.... 
Tyrosine kinase | Axl | Kidney cancer | Tyrosine-Protein Kinase Met (MET) | Platelet Derived Growth Factor Receptor (PDGFR) | Vascular endothelial growth factor receptor (VEGFR) | Fibroblast Growth factor Receptor (FGFR)
Journal Article
JOURNAL OF VIROLOGY, ISSN 0022-538X, 05/2018, Volume 92, Issue 9
Maraviroc is a CCR5 antagonist used in the treatment of HIV-1 infection. We and others have suggested that maraviroc could reactivate latent HIV-1. To test the... 
HIV-1 | maraviroc | HISTONE DEACETYLASE INHIBITOR | HIV infected | PROTEIN | latency | TRANSCRIPTION | INTENSIFICATION | AP-1 | VORINOSTAT | NF-kappa B | VIROLOGY | VIRUS-REPLICATION | IN-VIVO | GENE-EXPRESSION | persistence | LRA | reservoir | C-JUN | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 03/2017, Volume 216, Issue 3, p. 835
Vascular cell adhesion molecule 1 (VCAM-1) is an adhesion molecule assigned to the activated endothelium mediating immune cells adhesion and extravasation.... 
Physiological aspects | Immune response | Carcinoma, Renal cell | Observations | Cell adhesion | Cancer cells | Proteins | Molecules | Hypoxia | Correlation analysis | Cell adhesion & migration
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 08/2019, Volume 25, Issue 15, pp. 4846 - 4858
Purpose: Gasdermin B (GSDMB) overexpression/amplification occurs in about 60% of HER2 breast cancers, where it promotes cell migration, resistance to anti-HER2... 
SULFATIDE | SURVIVAL | AUTOINHIBITION | TRASTUZUMAB | ONCOLOGY | RESISTANCE | NANOCAPSULES | EXPRESSION | BINDING | PROGRESSION | STRATEGIES | Index Medicus
Journal Article
Cancers, ISSN 2072-6694, 03/2019, Volume 11, Issue 3, p. 346
microRNAs (miRNA) expression in colorectal (CR) primary tumours can facilitate a more precise molecular characterization. We identified and validated a miRNA... 
Biomarkers | MiRNAs | Patient stratification | Colorectal cancer | SUPPRESSOR | colorectal cancer | METASTASIS | miRNAs | biomarkers | patient stratification | YOUNG-PATIENTS | COLON | INFILTRATE | MICRORNAS | CANCER | PROGNOSTIC-FACTOR | ONCOLOGY | EXPRESSION | CARCINOMA
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 37, pp. 39941 - 39959
Cyclooxygenase2 (COX2) has been associated with cell growth, invasiveness, tumor progression and metastasis of colorectal carcinomas. However, the downstream... 
Early growth response 1 | Microsomal prostaglandin E | Colorectal adenocarcinoma | Cyclooxygenase 2 | synthase | Index Medicus
Journal Article
Journal Article
Transplantation, ISSN 0041-1337, 07/2018, Volume 102 Suppl 7S-1, pp. S59 - S60
BACKGROUNDDelayed graft function (DGF) is a common complication after deceased donor kidney transplantation (KT) which affects short and long-term outcome.... 
SURGERY | IMMUNOLOGY | TRANSPLANTATION
Journal Article
PLoS One, ISSN 1932-6203, 2012, Volume 7, Issue 9, pp. e44305 - e44305
Ischemia/reperfusion (I/R) is at the basis of renal transplantation and acute kidney injury. Molecular mechanisms underlying proximal tubule response to I/R... 
ISCHEMIA-REPERFUSION INJURY | EPITHELIAL-CELLS | RAT | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | ACUTE-RENAL-FAILURE | MICRORNAS | ACUTE-KIDNEY-INJURY | EXPRESSION | PATHOPHYSIOLOGY | HYDROXYLASES | Oligonucleotide Array Sequence Analysis | Molecular Sequence Data | Male | MicroRNAs - metabolism | Dextrans | Protein Isoforms - metabolism | Biological Transport | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Base Sequence | Kinesin - genetics | Binding Sites | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | Gene Expression | Kidney Tubules, Proximal - pathology | Reperfusion Injury - pathology | Signal Transduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Computational Biology | Rats | Fluorescein-5-isothiocyanate - analogs & derivatives | Cell Adhesion | Rats, Sprague-Dawley | Kinesin - metabolism | Animals | Kidney Tubules, Proximal - metabolism | Protein Binding | Protein Isoforms - genetics | Dextran | MicroRNA | Kidneys | Ischemia | Transplantation | Health aspects | Kinesin | Regulators | Target recognition | Trafficking | Genomes | Mimicry | Reperfusion | Rodents | Cell adhesion | Physiology | Tight junctions | Therapeutic applications | Interference | MiRNA | Gene expression | Adhesion | Polymerase chain reaction | Pathology | Molecular modelling | MicroRNAs | Cytoskeleton | Hypoxia | Kidney transplantation | Index Medicus
Journal Article