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1. Full Text Cell scientist to watch - Ana Garcia-Saez
by Garcia-Saez, Ana
Journal of cell science, ISSN 0021-9533, 09/2017, Volume 130, Issue 17, pp. 2773 - 2774
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Proteins | Medical research | Mitochondria | Molecular modelling | Microscopy | Cell death | Lipids | Cancer | Quantitative analysis
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2. Full Text Bax, Bak and beyond — mitochondrial performance in apoptosis
by Peña‐Blanco, Aida and García‐Sáez, Ana J
The FEBS journal, ISSN 1742-464X, 02/2018, Volume 285, Issue 3, pp. 416 - 431
BCL‐2 family | mitochondria | apoptosis | BAX | mitochondrial outer membrane permeabilization | BAK | DRP1 | BCL-2 family | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Mitochondrial Dynamics | Mitochondria - enzymology | bcl-2-Associated X Protein - chemistry | Proto-Oncogene Proteins c-bcl-2 - agonists | Humans | Protein Multimerization | bcl-2-Associated X Protein - agonists | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Mitochondrial Membranes - chemistry | Proto-Oncogene Proteins c-bcl-2 - chemistry | Mitochondrial Membranes - enzymology | Protein Interaction Domains and Motifs | Mitochondria - chemistry | Dimerization | Apoptosis Regulatory Proteins - chemistry | bcl-2-Associated X Protein - metabolism | Mitochondria - metabolism | Lipid Mobilization | Apoptosis Regulatory Proteins - metabolism | Mitochondrial Membranes - metabolism | Animals | Models, Biological | Apoptosis Regulatory Proteins - agonists | Protein Conformation | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | Porosity | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Apoptosis | bcl-2 Homologous Antagonist-Killer Protein - agonists | Mitochondria | Regulators | Oligomerization | Bax protein | Bcl-2 protein | Organelles | Index Medicus
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3. Full Text Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores
by Salvador‐Gallego, Raquel and Mund, Markus and Cosentino, Katia and Schneider, Jale and Unsay, Joseph and Schraermeyer, Ulrich and Engelhardt, Johann and Ries, Jonas and García‐Sáez, Ana J
The EMBO journal, ISSN 0261-4189, 02/2016, Volume 35, Issue 4, pp. 389 - 401
AFM | apoptosis | Bcl‐2 | pore‐forming protein | super‐resolution microscopy | Bcl-2 | pore-forming protein | super-resolution microscopy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Microscopy, Electron, Transmission | Mitochondria - enzymology | Pore Forming Cytotoxic Proteins - metabolism | Mitochondrial Membranes - physiology | Cytochromes c - metabolism | Humans | Protein Multimerization | bcl-2-Associated X Protein - metabolism | Permeability | Mitochondrial Membranes - metabolism | HeLa Cells | Microscopy, Fluorescence | Apoptosis | Cytoskeleton | Mitochondria | Microscopy | Index Medicus | Structural Biology | Membrane & Intracellular Transport | Autophagy & Cell Death
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4. Full Text Bax and Bak Pores: Are We Closing the Circle?
by Cosentino, Katia and García-Sáez, Ana J
Trends in cell biology, ISSN 0962-8924, 2016, Volume 27, Issue 4, pp. 266 - 275
Pathology | Bax | apoptosis | Bcl-2 proteins | mitochondrial outer membrane permeabilization | cell death | pore-forming proteins | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Models, Biological | Humans | Protein Multimerization | bcl-2-Associated X Protein - metabolism | Mitochondria - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Apoptosis | Oligomers | Cell death | Proteins | Cytochrome | Membranes | Regulators | Oligomerization | Bax protein | Homology | Cells | Studies | Cytochrome c | Molecules | Mitochondria | Molecular modelling | Pores | Dimers | Cellular stress response | Index Medicus
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5. Full Text Structural Model of Active Bax at the Membrane
by Bleicken, Stephanie and Jeschke, Gunnar and Stegmueller, Carolin and Salvador-Gallego, Raquel and García-Sáez, Ana J and Bordignon, Enrica
Molecular cell, ISSN 1097-2765, 11/2014, Volume 56, Issue 4, pp. 496 - 505
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Membrane - chemistry | Protein Structure, Tertiary | bcl-2-Associated X Protein - chemistry | Animals | Protein Structure, Secondary | Protein Multimerization | Protein Structure, Quaternary | Models, Molecular | Mice | Analysis | Mitochondrial DNA | Index Medicus
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6. Full Text MIM through MOM: the awakening of Bax and Bak pores
by Cosentino, Katia and García‐Sáez, Ana J
The EMBO journal, ISSN 0261-4189, 09/2018, Volume 37, Issue 17, p. n/a
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Bax protein | Immunogenicity | Immunomodulation | Extrusion | Pores | Mitochondrial DNA | Inflammation | Cytosol | Modulators | Deoxyribonucleic acid--DNA | Apoptosis | Index Medicus | Membrane & Intracellular Transport | Views | Autophagy & Cell Death | Signal Transduction
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7. Full Text Mechanistic Differences in the Membrane Activity of Bax and Bcl-xL Correlate with Their Opposing Roles in Apoptosis
by Bleicken, Stephanie and Wagner, Corinna and García-Sáez, Ana J
Biophysical journal, ISSN 0006-3495, 01/2013, Volume 104, Issue 2, pp. 421 - 431
Life Sciences & Biomedicine | Biophysics | Science & Technology | Humans | Protein Multimerization | bcl-2-Associated X Protein - metabolism | Mitochondrial Membranes - metabolism | Saccharomyces cerevisiae - metabolism | Unilamellar Liposomes - metabolism | Animals | Cattle | Models, Biological | Protein Binding | Mice | Lipid Bilayers - metabolism | Porosity | Protein Stability | bcl-X Protein - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Apoptosis | Cytochrome c | Proteins | Oligomers | Analysis | Oncology, Experimental | Mitochondrial DNA | Permeability | Research | Cancer | Membranes | Mitochondria | Index Medicus | Membrane
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8. Full Text Early activation of CD95 is limited and localized to the cytotoxic synapse
by Sánchez, María Florencia and Murad, Fabronia and Gülcüler Balta, Gülce S and Martin‐Villalba, Ana and García‐Sáez, Ana J and Carrer, Dolores C
The FEBS journal, ISSN 1742-464X, 08/2018, Volume 285, Issue 15, pp. 2813 - 2827
microcontact printing | fluorescence correlation spectroscopy | CD95/Fas/Apo1 | cytotoxic synapse | in vivo imaging | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cellular signal transduction | CD95 antigen | Mobility | Cytotoxicity | Activation | Lymphocytes T | Proteins | Signal transduction | Signaling | Killer cells | Biomedical materials | FasL protein | Lymphocytes | Antigen-presenting cells | Receptor mechanisms | Natural killer cells | Diffusion coefficient | Immune system | Apoptosis | Index Medicus
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9. Full Text MOMP in the absence of BH3-only proteins
by Sáez, Ana J. García and Villunger, Andreas
Genes & development, ISSN 0890-9369, 04/2016, Volume 30, Issue 8, pp. 878 - 880
Anti-apoptotic Bcl-2 proteins | Bax/Bak activation | Outer mitochondrial membrane | BH3-only | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Membrane Proteins - genetics | Humans | bcl-2 Homologous Antagonist-Killer Protein - genetics | bcl-2-Associated X Protein - metabolism | Apoptosis - genetics | Mitochondria - metabolism | Permeability | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Apoptosis Regulatory Proteins - metabolism | Mitochondrial Membranes - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Mitochondria - genetics | Models, Biological | CRISPR-Cas Systems | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | bcl-2-Associated X Protein - genetics | Cellular proteins | Mitochondria | Research | Cell death | Index Medicus | 4 | Outlook | outer mitochondrial membrane | Bax | anti-apoptotic Bcl-2 proteins | Bak activation
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10. Full Text Mitochondrial alterations in apoptosis
by Cosentino, Katia and García-Sáez, Ana J
Chemistry and physics of lipids, ISSN 0009-3084, 2014, Volume 181, pp. 62 - 75
Bcl-2 family proteins | Cristae remodeling | Cardiolipin | Mitochondrial outer membrane permeabilization | Mitochondrial fission | Apoptosis | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Mitochondrial Membranes - secretion | Animals | Cytochromes c - secretion | Humans | Mitochondria - metabolism | Permeability | Mitochondrial Membranes - metabolism | Proteins | Index Medicus
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