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by Petrylak, Daniel and Petrylak, Daniel P and de Wit, Ronald and Chi, Kim Nguyen and Chi, Kim N and Drakaki, Alexandra and Sternberg, Cora N and Nishiyama, Hiroyuki and Castellano, Daniel and Hussain, Syed and Fléchon, Aude and Bamias, Aristotelis and Yu, Evan Y and van der Heijden, Michiel S and Matsubara, Nobuaki and Alekseev, Boris and Necchi, Andrea and Géczi, Lajos and Ou, Yen-Chuan and Coskun, Hasan Senol and Su, Yu-Li and Su, Wen-Pin and Hegemann, Miriam and Percent, Ivor and Percent, Ivor J and Lee, Yun-Gyoo and Lee, Hyo Jin and Lee, Jae-Lyun and Tucci, Marcello and Semenov, Andrey and Laestadius, Fredrik and Peer, Avivit and Tortora, Giampaolo and Safina, Sufia Z and Safina, Sufia and del Muro, Xavier Garcia and Rodriguez-Vida, Alejo and Cicin, Irfan and Harputluoglu, Hakan and Widau, Ryan C and Liepa, Astra M and Walgren, Richard A and Hamid, Oday and Zimmermann, Annamaria H and Bell-McGuinn, Katherine M and Powles, Thomas and Wong, Suet-Lai Shirley and Tan, Thean Hsiang and Hovey, Elizabeth Jane and Clay, Timothy Dudley and Ng, Siobhan Su Wan and Rutten, Annemie and Machiels, Jean-Pascal and Dumez, Herlinde and Cheng, Susanna Yee-Shan and Ferrario, Cristiano and Sengeloev, Lisa and Jensen, Niels Viggo and Thibault, Constance and Laguerre, Brigitte and Joly, Florence and Flechon, Aude and Culine, Stéphane and Becht, Catherine and Niegisch, Günter and Stöckle, Michael and Grimm, Marc-Oliver and Gakis, Georgios and Schultze-Seemann, Wolfgang and Kalofonos, Haralambos and Mavroudis, Dimitrios and Papandreou, Christos and Karavasilis, Vasilis and Révész, Janos and Geczi, Lajos and Rosenbaum, Eli and Leibowitz-Amit, Raya and Kejzman, Daniel and Sarid, David and Scagliotti, Giorgio Vittorio and Bracarda, Sergio and Massari, Francesco and Osawa, Takahiro and Miyajima, Naoto and Shinohara, Nobuo and Fukuta, Fumimasa and Ohyama, Chikara and Obara, Wataru and Yamashita, Shinichi and Tomita, Yoshihiko and Kawai, Koji and Fukasawa, Satoshi and Oyama, Masafumi and Yonese, Junji and Nagata, Masayoshi and Uemura, Motohide and Nishimura, Kazuo and Kawakita, Mutsushi and Tsunemori, Hiroyuki and Hashine, Katsuyoshi and ... and RANGE Study Investigators and RANGE study investigators
The Lancet, ISSN 0140-6736, 11/2017, Volume 390, Issue 10109, pp. 2266 - 2277
Few treatments with a distinct mechanism of action are available for patients with platinum-refractory advanced or metastatic urothelial carcinoma. We assessed... 
BREAST-CANCER | BLADDER-CANCER | LUNG-CANCER | 2ND-LINE THERAPY | TRANSITIONAL-CELL-CARCINOMA | FOLLOW-UP | OPEN-LABEL | FACTOR RECEPTOR-2 | II TRIAL | ENDOTHELIAL GROWTH-FACTOR | MEDICINE, GENERAL & INTERNAL | CISPLATIN | DOXORUBICIN | METHOTREXATE | VINBLASTINE | COMBINATION | Carcinoma, Transitional Cell - mortality | Prognosis | Humans | Middle Aged | Male | Neoplasm Invasiveness - pathology | Urinary Bladder Neoplasms - pathology | Adult | Female | Urinary Bladder Neoplasms - mortality | Double-Blind Method | Risk Assessment | Docetaxel | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Urinary Bladder Neoplasms - drug therapy | Disease-Free Survival | Taxoids - administration & dosage | Carcinoma, Transitional Cell - pathology | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Internationality | Neoadjuvant Therapy - methods | Carcinoma, Transitional Cell - drug therapy | Survival Analysis | Aged | Neoplasm Staging | Antimitotic agents | Care and treatment | Carcinoma | Analysis | Clinical trials | Product development | Metastasis | Antineoplastic agents | Cancer | Cytotoxicity | Oncology | Patients | Cancer therapies | Metastases | Angiogenesis | Chemotherapy | Platinum | Medical prognosis | Ligands | Clinical medicine | Urothelial carcinoma | Vascular endothelial growth factor | Apoptosis
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 08/2009, Volume 27, Issue 22, pp. 3584 - 3590
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2009, Volume 10, Issue 11, pp. 1045 - 1052
Summary Background Adjuvant imatinib mesylate prolongs recurrence-free survival (RFS) after resection of localised primary gastrointestinal stromal tumours... 
Hematology, Oncology and Palliative Medicine | DISEASE-SPECIFIC SURVIVAL | ONCOLOGY | C-KIT MUTATION | POOR-PROGNOSIS | RISK STRATIFICATION | GASTRIC-CARCINOMA | MUSCLE TUMORS | RADICAL PROSTATECTOMY | POSTOPERATIVE NOMOGRAM | IMATINIB MESYLATE | NIH CONSENSUS CRITERIA | Predictive Value of Tests | United States - epidemiology | Gastrointestinal Stromal Tumors - secondary | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Patient Selection | Young Adult | Time Factors | Nomograms | Aged, 80 and over | Adult | Female | Registries | Retrospective Studies | Chemotherapy, Adjuvant | Gastrointestinal Stromal Tumors - mortality | Child | Reproducibility of Results | Gastrointestinal Stromal Tumors - surgery | Risk Assessment | Neoplasm Invasiveness | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Piperazines - therapeutic use | Imatinib Mesylate | Disease-Free Survival | Mitotic Index | Digestive System Surgical Procedures | Gastrointestinal Stromal Tumors - drug therapy | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Spain - epidemiology | Adolescent | Aged | Benzamides | Neoplasm Staging | Sarcoma | Surgery | Singers | recurrence | GIST | gastrointestinal stromal tumor | survival | nomogram | imatinib mesylate | prognosis | staging | surgery
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2009, Volume 27, Issue 12, pp. 2102 - 2103
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71449
Angiogenesis is the result of the combined activity of the tumor microenvironment and signaling molecules. The angiogenic switch is represented as an imbalance... 
TARGET | EPHA2 RECEPTOR | ACTIVATION | INVASION | TYROSINE KINASE | EWS/FLI-1 | MULTIDISCIPLINARY SCIENCES | EPHRINS | TUMOR | EXPRESSION | FAMILY | Humans | Receptor, EphA2 - metabolism | Sarcoma, Ewing - pathology | Bone Neoplasms - pathology | Cell Movement - genetics | Bone Neoplasms - metabolism | Heterografts | Female | Transcription, Genetic | Tumor Burden - genetics | Bone Neoplasms - genetics | Proto-Oncogene Proteins c-akt - metabolism | Disease Models, Animal | Sarcoma, Ewing - metabolism | Signal Transduction | Endothelial Cells - metabolism | Fibroblast Growth Factor 2 - biosynthesis | Gene Silencing | Caveolin 1 - genetics | Mice, Knockout | Protein Transport | Caveolin 1 - metabolism | Animals | Fibroblast Growth Factor 2 - genetics | Receptor, EphA2 - genetics | Cell Line, Tumor | Protein Binding | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Sarcoma, Ewing - genetics | Tyrosine | Development and progression | Fibroblast growth factors | Sarcoma | Phosphotransferases | Endothelium | Caveolin-1 | Laboratories | AKT protein | Biology | Metastasis | Kinases | Inactivation | Ewing's sarcoma | Cell adhesion & migration | Proteins | Angiogenesis | Signal transduction | Rodents | Fibroblasts | Protein-tyrosine kinase receptors | Nutrients | Children | Localization | Growth factors | Protein-tyrosine kinase | EphA2 protein | Fibroblast growth factor 2 | Ephrins | Young adults | Deactivation | Caveolin | Gene expression | Endothelial cells | Signaling | Neural networks | Ligands | Adults | Solid tumors | Prostate cancer | Cell migration | Tumors | Sarcoma d'Ewing | Neovascularization | Angiogènesi | Endoteli
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2009, Volume 27, Issue 12, pp. 2102 - 2103
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 3405 - 3405
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The Lancet Oncology, ISSN 1470-2045, 08/2017, Volume 18, Issue 8, pp. 1089 - 1103
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Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 18, pp. 2528 - 2533
Journal Article