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Brain : a journal of neurology, ISSN 0006-8950, 03/2018, Volume 141, Issue 3, p. 786
The increasing evidence supporting a role for B cells in the pathogenesis of multiple sclerosis prompted us to investigate the influence of known... 
Journal Article
Emerging Microbes and Infections, 12/2018, Volume 7, Issue 1
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2017, Volume 140, Issue 5, pp. 1394 - 1403.e8
Background Severe combined immunodeficiency can be caused by loss-of-function mutations in genes involved in the DNA recombination machinery, such as... 
Allergy and Immunology | Leaky severe combined immunodeficiency | Artemis | regulatory T cell | cytotoxic T-lymphocyte-associated protein 4 | immune dysregulation | CELLS | APOPTOSIS | HOMEOSTASIS | V(D)J RECOMBINATION | PHENOTYPE | OMENN-SYNDROME | IMMUNOLOGY | DEFICIENCY | ALLERGY | MUTATIONS | FOXP3(+) | T-Lymphocytes - physiology | Endonucleases - genetics | Lymphocyte Activation | Recombinational DNA Repair - genetics | Humans | Mice, Inbred C57BL | Cells, Cultured | B-Lymphocytes - physiology | Severe Combined Immunodeficiency - therapy | Male | Mice, Transgenic | Inflammation - immunology | Severe Combined Immunodeficiency - immunology | Inflammation - therapy | Severe Combined Immunodeficiency - genetics | Animals | Abatacept - therapeutic use | Inflammation - genetics | Cell Differentiation | Mice | Nuclear Proteins - genetics | Disease Models, Animal | Autoimmunity | Crosslinked polymers | Severe combined immunodeficiency | Analysis | Disease susceptibility | B cells | T cells | Flow cytometry | Animal models | Recombination | Disease | Genes | Differentiation (biology) | Medical services | Immunoglobulin E | Cytotoxicity | Lymphocytes T | Infections | Dermatitis | RAG gene | DNA repair | Proteins | T-cell receptor | Genotype & phenotype | Cell activation | Lymphocytes | Rodents | Bone marrow | Deoxyribonucleic acid--DNA | Enzyme-linked immunosorbent assay | Immune response | Cell survival | Secretion | Therapeutic applications | Test procedures | Crosslinking | T cell receptors | Histology | Cell differentiation | Patients | Disease control | Cytometry | RAG2 protein | Lymphocytes B | RAG1 protein | Colitis | Mutation
Journal Article
Journal Article
Gut, ISSN 0017-5749, 08/2016, Volume 65, Issue 8, pp. 1279 - 1288
ObjectivePsychological factors increase the risk to develop postinfectious IBS (PI-IBS), but the mechanisms involved are unclear. As stress affects the immune... 
IGE | IRRITABLE BOWEL SYNDROME | ENTEROCHROMAFFIN CELL | DEPRESSION SCALE | PROGNOSIS | BACTERIAL DYSENTERY | IMMUNE ACTIVATION | HOSPITAL ANXIETY | MECHANISMS | OUTBREAK | STRESS | GASTROENTEROLOGY & HEPATOLOGY | IRRITABLE-BOWEL-SYNDROME | Campylobacter Infections - complications | Biopsy - methods | Gastroenteritis - epidemiology | Outcome Assessment (Health Care) | Rectum - pathology | Cytokines - analysis | Humans | Middle Aged | Giardiasis - epidemiology | Gastroenteritis - microbiology | Male | Stress, Psychological - diagnosis | Stress, Psychological - immunology | Psychiatric Status Rating Scales | Campylobacter jejuni - isolation & purification | Disease Outbreaks | Irritable Bowel Syndrome - diagnosis | Stress, Psychological - epidemiology | Irritable Bowel Syndrome - psychology | Adult | Female | Irritable Bowel Syndrome - etiology | Surveys and Questionnaires | Gastroenteritis - immunology | Rectum - microbiology | Disease Susceptibility - psychology | Giardia lamblia - isolation & purification | Giardiasis - complications | Belgium - epidemiology | Comorbidity | Risk Factors | Gastroenteritis - complications | Drinking Water - analysis | Campylobacter Infections - immunology | Drinking Water - microbiology | Campylobacter Infections - epidemiology | Giardiasis - immunology | Stress, Psychological - physiopathology | Research | Gastroenteritis | Risk factors | Irritable bowel syndrome | Immune system
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2016, Volume 48, Issue 5, pp. 519 - 527
Journal Article
Science Translational Medicine, ISSN 1946-6234, 03/2016, Volume 8, Issue 332, pp. 332ra45 - 332ra45
Journal Article
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 08/2018, Volume 142, Issue 2, pp. 699 - 702.e12
IKAROS function is conserved across species, with Kuehn et al3 identifying novel heterozygous IKZF1 mutations as the cause of an autosomal-dominant form of... 
B-CELLS | MUTATIONS | IMMUNOLOGY | ALLERGY | EXPRESSION | Lupus | Anticoagulants | Immunoglobulins | Ikaros protein | Gene expression | Hepatitis | Immunology | Lymphocytes | Transgenic animals | Genetic testing | Mutation | Deoxyribonucleic acid--DNA | Age | Life Sciences | Microbiology and Parasitology | Bacteriology | Virology | systemic lupus erythematosus | IKZF1 | B cells | autoimmunity | IKAROS | CD22
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 08/2018, Volume 142, Issue 2, pp. 630 - 646
Roifman syndrome is a rare inherited disorder characterized by spondyloepiphyseal dysplasia, growth retardation, cognitive delay, hypogammaglobulinemia, and,... 
B cells | RNA processing | Roifman syndrome | platelets | DEVELOPMENTAL DISORDER | HERMANSKY-PUDLAK-SYNDROME-1 HPS1 | PLATELET | DISORDER MOPD I | IMMUNOLOGY | BAFF-R | MINOR SPLICEOSOME | BIOGENESIS | ALLERGY | U4ATAC SNRNA | EXPRESSION | IMMUNODEFICIENCY | Retinal Diseases - genetics | Cell Proliferation | Humans | Child, Preschool | Infant | Protein Splicing - genetics | Blood Platelets - physiology | Cardiomyopathies - genetics | Mental Retardation, X-Linked - genetics | Osteochondrodysplasias - genetics | RNA, Small Nuclear - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Cell Differentiation | Child | Cells, Cultured | B-Lymphocytes - physiology | Megakaryocytes - physiology | Signal Transduction - genetics | Whole Exome Sequencing | Cell Lineage | Pedigree | Adolescent | Immunologic Deficiency Syndromes - genetics | Precursor Cells, B-Lymphoid - physiology | Mitogen-Activated Protein Kinase 1 - metabolism | Flow cytometry | Growth rate | Genes | Cognitive ability | Hypogammaglobulinemia | snRNA | Defects | Gene sequencing | Dwarfism | Proteins | Genotype & phenotype | Tubulin | Blood platelets | Actin | Lymphocytes | Megakaryocytes | Thrombocytopenia | Dysplasia | Splicing | MAP kinase | Patients | Ribonucleic acids | Lymphocytes B | Granular materials | Protein kinase | Differentiation | Platelets | Binding sites
Journal Article
Brain, ISSN 0006-8950, 03/2018, Volume 141, Issue 3, pp. 786 - 796
Increasing evidence implicates B cells in the pathogenesis of multiple sclerosis. Smets et al. report that the CD40 multiple sclerosis risk allele lowers CD40... 
CD86 | CD40 | Multiple sclerosis | B cells | Susceptibility | ENCEPHALOMYELITIS | susceptibility | CD40 EXPRESSION | multiple sclerosis | SUSCEPTIBILITY LOCI | SINGLE-NUCLEOTIDE POLYMORPHISM | NEUROSCIENCES | CLINICAL NEUROLOGY | RESPONSES | MEMORY | GRAVES-DISEASE | T-CELLS | GENOME-WIDE ASSOCIATION | ANTIGEN | Original
Journal Article
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 10/2019, Volume 10
Cytometry by Time-Of-Flight (CyTOF) uses antibodies conjugated to isotopically pure metals to identify and quantify a large number of cellular features with... 
normalization | anchor | clinical studies | DEFINES | mass cytometry | LEUKEMIA | IMMUNOLOGY | human immunology | barcode | EXPRESSION | SIGNATURE | CORRELATE
Journal Article