X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (55) 55
animals (46) 46
index medicus (41) 41
dna, mitochondrial - genetics (33) 33
biochemistry & molecular biology (31) 31
cell biology (26) 26
male (26) 26
female (25) 25
mitochondrial dna (23) 23
mutation (22) 22
mitochondria (20) 20
mitochondria - metabolism (20) 20
base sequence (19) 19
molecular sequence data (19) 19
amino acid sequence (16) 16
drosophila melanogaster - genetics (16) 16
mitochondria - genetics (15) 15
cell line (14) 14
drosophila (14) 14
oxidative phosphorylation (13) 13
biotechnology & applied microbiology (12) 12
genetics & heredity (12) 12
pluripotent stem-cells (12) 12
cell & tissue engineering (11) 11
disease (11) 11
genetic aspects (11) 11
adult (10) 10
developmental biology (10) 10
dna, mitochondrial - metabolism (10) 10
medicine (10) 10
middle aged (10) 10
mitochondria - enzymology (10) 10
research (10) 10
transcription, genetic (10) 10
dna polymerase gamma (9) 9
drosophila proteins - metabolism (9) 9
gene (9) 9
medicina (9) 9
mice (9) 9
mitochondrial proteins - genetics (9) 9
mitochondrial proteins - metabolism (9) 9
mutation - genetics (9) 9
phenotype (9) 9
transcription factors - metabolism (9) 9
analysis (8) 8
apoptosis (8) 8
biology (8) 8
clinical neurology (8) 8
dna (8) 8
dna-directed dna polymerase - genetics (8) 8
drosophila melanogaster (8) 8
drosophila proteins - genetics (8) 8
expression (8) 8
gene expression (8) 8
genes (8) 8
genetic research (8) 8
mitochondrial diseases - genetics (8) 8
transcription factors - genetics (8) 8
cloning, molecular (7) 7
defects (7) 7
electron transport complex iv - metabolism (7) 7
fibroblasts (7) 7
gene expression regulation, developmental (7) 7
gene mutations (7) 7
oxidative stress (7) 7
pedigree (7) 7
aged (6) 6
article (6) 6
atp synthase (6) 6
binding protein (6) 6
cell differentiation (6) 6
cells, cultured (6) 6
chromosome mapping (6) 6
cloning (6) 6
disease models, animal (6) 6
disorders (6) 6
dna mutational analysis (6) 6
drosophila melanogaster - metabolism (6) 6
gene-expression (6) 6
induced pluripotent stem cells - cytology (6) 6
induced pluripotent stem cells - metabolism (6) 6
messenger-rna (6) 6
point mutation (6) 6
progressive external ophthalmoplegia (6) 6
reactive oxygen species - metabolism (6) 6
research article (6) 6
rna, messenger - genetics (6) 6
sequence (6) 6
stem cells (6) 6
accessory subunit (5) 5
aging (5) 5
artemia - embryology (5) 5
artemia - genetics (5) 5
biochemistry (5) 5
bioenergetics (5) 5
biophysics (5) 5
cardiomyopathy (5) 5
deoxyribonucleic acid--dna (5) 5
dna replication (5) 5
dna-binding proteins - metabolism (5) 5
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Medicina Clinica, ISSN 0025-7753, 05/2016, Volume 146, Issue 9, pp. 408 - 412
Journal Article
Brain, ISSN 0006-8950, 2/2008, Volume 131, Issue 2, pp. 338 - 351
Mutations in OPA1, a dynamin-related GTPase involved in mitochondrial fusion, cristae organization and control of apoptosis, have been linked to non-syndromic... 
Chronic progressive external ophthalmoplegia | Dominant optic atrophy | Mitochondrial encephalomyopathy | Mitochondria | mtDNA multiple deletions | PROTEIN | mitochondria | NEUROSCIENCES | chronic progressive external ophthalmoplegia | R445H MUTATION | CLINICAL NEUROLOGY | mitochondrial encephalomyopathy | PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA | NEUROGASTROINTESTINAL ENCEPHALOMYOPATHY | HEARING-LOSS | GENE | DISEASE | dominant optic atrophy | DEAFNESS | FISSION | DELETIONS | Ophthalmoplegia, Chronic Progressive External - pathology | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Mutation, Missense | DNA Mutational Analysis - methods | Ophthalmoplegia, Chronic Progressive External - genetics | DNA, Mitochondrial - genetics | Base Sequence | Muscle, Skeletal - chemistry | Adult | Female | Optic Atrophy, Autosomal Dominant - pathology | Child | Muscle, Skeletal - ultrastructure | Models, Molecular | Fibroblasts - pathology | Mitochondrial Myopathies - pathology | Syndrome | Magnetic Resonance Imaging | Point Mutation | Mitochondrial Myopathies - genetics | GTP Phosphohydrolases - genetics | Pedigree | Optic Atrophy, Autosomal Dominant - genetics | Aged | GTP Phosphohydrolases | Neurons and Cognition | DNA, Mitochondrial | Life Sciences | DNA Mutational Analysis | Fibroblasts | Optic Atrophy, Autosomal Dominant | Mitochondrial Myopathies | Ophthalmoplegia, Chronic Progressive External | Muscle, Skeletal
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 11/2016, Volume 231, Issue 11, pp. 2317 - 2318
Mitochondrial disorders, although individually are rare, taken together constitute a big group of diseases that share a defect in the oxidative phosphorylation... 
PLURIPOTENT STEM-CELLS | PHYSIOLOGY | LINE | PATIENT | GENERATION | INDUCTION | CELL BIOLOGY | Mitochondrial Diseases - genetics | Humans | Induced Pluripotent Stem Cells - transplantation | Polymorphism, Single Nucleotide - genetics | DNA Copy Number Variations - genetics | Mitochondrial Diseases - therapy | Mutation - genetics | Health aspects | Stem cells
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0164199
Introduction The generation of Rho-0 cells requires the use of an immortalization process, or tumor cell selection, followed by culture in the presence of... 
RHODAMINE 6G | OXIDATIVE STRESS | IN-VITRO | MITOCHONDRIAL RESPIRATORY-CHAIN | NUCLEOSIDE ANALOGS | 1-METHYL-4-PHENYLPYRIDINIUM ION MPP | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | ANTIOXIDANT ENZYMES | METABOLIC PLASTICITY | MTDNA MUTATIONS | Cell Line | Reactive Oxygen Species - metabolism | DNA, Mitochondrial - metabolism | Humans | Mesenchymal Stromal Cells - metabolism | DNA, Mitochondrial - analysis | Mitochondria - metabolism | DNA - metabolism | DNA, Mitochondrial - isolation & purification | DNA - isolation & purification | Mesenchymal Stromal Cells - cytology | Phenotype | Flow Cytometry | Membrane Potential, Mitochondrial | Cell Differentiation | Real-Time Polymerase Chain Reaction | Apoptosis | Mitochondrial DNA | Chemical tests and reagents | Gene expression | Genes | Stem cells | Drugs | Cell culture | Flow cytometry | Phosphorylation | Disease | Mesenchyme | Pathogenesis | Biosynthesis | Genomes | Stavudine | Cell surface | Biomedical materials | Mitochondria | Ethidium bromide | DNA methylation | Fibroblasts | Bone marrow | Biocompatibility | Membrane potential | Chondrogenesis | Deoxyribonucleic acid--DNA | Adipogenesis | Enzymes | Phenotypes | Metabolism | Real time | Polymerase chain reaction | Cytometry | Immortalization | Reagents | Cell lines | Uridine | Mutation | Electron transport | Differentiation | Osteogenesis | Deoxyribonucleic acid | DNA
Journal Article
Stem Cell Research, ISSN 1873-5061, 04/2019, Volume 36, p. 101418
A mouse iPSC line, IISHDOi005-A, generated from fibroblasts obtained from a mouse C57BL/6J with an age of 1 year and a half, has been obtained. For this... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Fibroblasts | Research | Analysis | Cell lines | Stem cells
Journal Article
Stem Cell Research, ISSN 1873-5061, 04/2018, Volume 28, pp. 131 - 135
We have generated a human iPSC line, IISHDOi002-A, from commercial primary normal human dermal fibroblasts belonging to an African mitochondrial haplogroup... 
PLURIPOTENT STEM-CELLS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1 - 14
Mitochondrial protein synthesis requires charging mt-tRNAs with their cognate amino acids by mitochondrial aminoacyl-tRNA synthetases, with the exception of... 
Pathogens | Charging | Aminoacylation | tRNA | Cardiomyopathy | Disorders | Amino acids | Homology | Protein biosynthesis | Patients | Defects | Proteins | Pathogenicity | Mitochondria | Protein synthesis | Fibroblasts | Electron transport | Glutamine
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e43954
The human gene C10orf2 encodes the mitochondrial replicative DNA helicase Twinkle, mutations of which are responsible for a significant fraction of cases of... 
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA | MUTANT | DNA-POLYMERASE-GAMMA | REPLICATION | MULTIDISCIPLINARY SCIENCES | MULTIPLE DELETIONS | LINKER REGION | DISORDERS | PROTEINS | HELICASE | THYMIDINE PHOSPHORYLASE | Mitochondrial Diseases - pathology | Cell Proliferation | Drosophila melanogaster - physiology | Humans | Apoptosis - genetics | Male | Mitochondrial Proteins - genetics | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Mitochondria - genetics | DNA Helicases - genetics | Disease Models, Animal | Mitochondrial Diseases - genetics | Amino Acid Sequence | DNA Helicases - chemistry | Ophthalmoplegia - pathology | Oxidative Phosphorylation | Mitochondria - metabolism | Longevity - genetics | Mitochondria - pathology | Ophthalmoplegia - enzymology | Mitochondrial Diseases - enzymology | Animals | Mitochondrial Proteins - chemistry | Mice | Ophthalmoplegia - genetics | Mutation | Gene mutations | Drosophila | Physiological aspects | Development and progression | Mitochondrial diseases | Genetic aspects | Research | Apoptosis | Cell proliferation | Phenotypes | Phosphorylation | Copy number | Mitochondrial DNA | Kinases | Gene expression | Defects | DNA helicase | Mitochondria | Life span | Oxidative phosphorylation | Cell death | Ophthalmoplegia | Deoxyribonucleic acid--DNA | Deoxyribonucleic acid | DNA
Journal Article