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Molecular Cancer Therapeutics, ISSN 1535-7163, 12/2015, Volume 14, Issue 12 Supplement 2, pp. PL08-04 - PL08-04
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 20 - 20
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2015, Volume 112, Issue 29, pp. E3800 - E3805
The organometallic “half-sandwich” compound [Os(η⁶- -cymene) (4-(2-pyridylazo)- -dimethylaniline)I]PF₆ is 49× more potent than the clinical drug cisplatin in... 
Protein microarrays | Organometallic anticancer compound | Mitochondria | Transcriptome sequencing | Cancer metabolism | MITOCHONDRIAL-DNA MUTATIONS | APOPTOSIS | OXIDATIVE STRESS | PROTEIN | mitochondria | MULTIDISCIPLINARY SCIENCES | organometallic anticancer compound | DAMAGE | cancer metabolism | transcriptome sequencing | DISEASE | TARGETS | ANTICANCER COMPLEXES | AGENTS | METALLODRUGS | protein microarrays | Apoptosis - drug effects | Humans | Ovarian Neoplasms - pathology | Neoplasms, Glandular and Epithelial - metabolism | Gene Expression Profiling | Osmium Compounds - pharmacology | Transcription Factor AP-1 - metabolism | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | DNA, Mitochondrial - genetics | Mitochondria - genetics | DNA Damage - genetics | Organometallic Compounds - therapeutic use | Female | Ovarian Neoplasms - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Ovarian Neoplasms - drug therapy | Neoplasms, Glandular and Epithelial - pathology | Osmium Compounds - chemistry | Chromosomes, Human - genetics | Oxidative Stress - genetics | Mutation - genetics | Sequence Analysis, RNA | NF-E2-Related Factor 2 - metabolism | Neoplasms, Glandular and Epithelial - drug therapy | Osmium Compounds - therapeutic use | Carcinoma, Ovarian Epithelial | Cell Line, Tumor | Organometallic Compounds - chemistry | Oxidative Stress - drug effects | Organometallic Compounds - pharmacology | Usage | Platinum compounds | Genetic aspects | Research | Drug therapy | Health aspects | Ovarian cancer | Phosphorylation | Organic chemicals | Metabolism | Cancer therapies | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Cell, ISSN 0092-8674, 05/2015, Volume 161, Issue 4, pp. 933 - 945
Journal Article
Journal Article
Cell, ISSN 0092-8674, 07/2016, Volume 166, Issue 3, pp. 740 - 754
Journal Article
GENOME BIOLOGY, ISSN 1474-760X, 02/2019, Volume 20, Issue 1, pp. 27 - 27
Journal Article
Journal Article
Nature, ISSN 0028-0836, 03/2012, Volume 483, Issue 7391, pp. 570 - 575
Journal Article
Nature Medicine, ISSN 1078-8956, 2017, Volume 23, Issue 12, pp. 1424 - 1435
Human liver cancer research currently lacks in vitro models that can faithfully recapitulate the pathophysiology of the original tumor. We recently described a... 
MEDICINE, RESEARCH & EXPERIMENTAL | CHOLANGIOCARCINOMA | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | ESTABLISHMENT | GENOME | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | IN-VITRO EXPANSION | ADULT LIVER | EXPRESSION | INACTIVATING MUTATIONS | Cell Proliferation | Primary Cell Culture - methods | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Male | Antineoplastic Agents - therapeutic use | Carcinoma, Hepatocellular - drug therapy | Antineoplastic Agents - isolation & purification | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Bile Duct Neoplasms - genetics | Tumor Cells, Cultured | Bile Duct Neoplasms - drug therapy | Precision Medicine | Drug Screening Assays, Antitumor - methods | Organoids - pathology | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | Mice, SCID | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - drug therapy | Carcinoma, Hepatocellular - pathology | Cholangiocarcinoma - genetics | Mice, Inbred NOD | Mice | Bile Duct Neoplasms - pathology | Cell culture | Liver cancer | Development and progression | Usage | Models | Research | Propagation | Liver | Hepatocellular carcinoma | Tissues | Drug screening | Metastases | Utilities | Biomedical materials | Organoids | Xenografts | Bioindicators | Cholangiocarcinoma | Extracellular signal-regulated kinase | Cultures | Pharmacology | Gene expression | Chemical compounds | Screening | Hepatocytes | Biomarkers | In vivo methods and tests | Tumors | Cancer | Index Medicus
Journal Article