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Journal of clinical oncology, ISSN 1527-7755, 2013, Volume 31, Issue 15, pp. 1806 - 1814
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2016, Volume 352, Issue 6282, pp. 189 - 196
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 7/2011, Volume 108, Issue 30, pp. 12372 - 12377
Journal Article
Cell reports (Cambridge), ISSN 2211-1247, 2016, Volume 15, Issue 4, pp. 857 - 865
Large-scale genomic characterization of tumors from prospective cohort studies may yield new insights into cancer pathogenesis. We performed whole-exome... 
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 01/2017, Volume 13, Issue 1, pp. 905 - n/a
Treatment of BRAF‐mutant melanomas with MAP kinase pathway inhibitors is paradigmatic of the promise of precision cancer therapy but also highlights problems... 
adaptive and reversible drug resistance | RAF and MEK inhibitors | BRAFV600E melanomas | de‐differentiated NGFRHigh state | melanomas | BRAF | de-differentiated NGFR | state | CANCER-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACQUIRED-RESISTANCE | SENSITIVITY | de-differentiated NGFR(High) state | RECEPTOR | CONFERS RESISTANCE | BRAF INHIBITION | BRAF(V600E) melanomas | EVOLUTION | PATHWAY | DYNAMICS | REVEALS | Cell Survival - drug effects | Humans | Gene Expression Profiling - methods | Sulfonamides - pharmacology | Nerve Tissue Proteins - genetics | Indoles - administration & dosage | Receptors, Nerve Growth Factor - genetics | Xenograft Model Antitumor Assays | Vemurafenib | Animals | MAP Kinase Signaling System - drug effects | Cell Differentiation - drug effects | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Indoles - pharmacology | Cell Proliferation - drug effects | Mice | Gene Expression Regulation, Neoplastic - drug effects | Mutation | Single-Cell Analysis | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | Pharmacology | Microbiology | Kinases | Drug resistance | Cancer therapies | Melanoma | Drugs | Biotechnology | Profiling | Transcription | Xenotransplantation | Raf protein | Drug delivery | Experiments | Cell cycle | Xenografts | Extracellular matrix | Drug dosages | Growth factors | Phenotypes | Statistical analysis | Tumor cells | MEK inhibitors | Cloning | Medical school libraries | MAP kinase | MEK kinase | Gene expression | Neural crest | Variance analysis | Inhibitors | Nerve growth factor receptors | Tumors | Apoptosis
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2010, Volume 28, Issue 35, pp. 5219 - 5228
Cancer is a disease of the genome. Most tumors harbor a constellation of structural genomic alterations that may dictate their clinical behavior and treatment... 
HUMAN BREAST | GENE | ONCOLOGY | C-MYC | SMALL-CELL LUNG | PHASE-II | TRANS-RETINOIC ACID | LEUKEMIA | SOMATIC MUTATIONS | IMATINIB MESYLATE | LINEAGE-SURVIVAL ONCOGENE | Animals | Neoplasms - genetics | Genome, Human | Humans | Precision Medicine - methods | Bon | Biology of Neoplasia
Journal Article
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, pp. 1324 - 13
Journal Article
Nature medicine, ISSN 1546-170X, 2016, Volume 22, Issue 3, pp. 298 - 305
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2013, Volume 153, Issue 1, pp. 17 - 37
Journal Article