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by Anttila, Verneri and Bulik-Sullivan, Brendan and Finucane, Hilary K and Walters, Raymond K and Bras, Jose and Duncan, Laramie and Escott-Price, Valentina and Falcone, Guido J and Gormley, Padhraig and Malik, Rainer and Patsopoulos, Nikolaos A and Ripke, Stephan and Wei, Zhi and Yu, Dongmei and Lee, Phil H and Grenier-Boley, Benjamin and Chouraki, Vincent and Kamatani, Yoichiro and Berr, Claudine and Letenneur, Luc and Hannequin, Didier and Amouyel, Philippe and Boland, Anne and Deleuze, Jean-François and Duron, Emmanuelle and Vardarajan, Badri N and Reitz, Christiane and Goate, Alison M and Huentelman, Matthew J and Rogaeva, Ekaterina and St George-Hyslop, Peter and Hakonarson, Hakon and Kukull, Walter A and Farrer, Lindsay A and Beach, Thomas G and Head, Elizabeth and Jicha, Gregory A and Kauwe, John S.K and Kaye, Jeffrey A and Levey, Allan I and Lieberman, Andrew P and Pankratz, Vernon S and Poon, Wayne W and Quinn, Joseph F and Saykin, Andrew J and Schneider, Lon S and Smith, Amanda G and Sonnen, Joshua A and Stern, Robert A and Van Eldik, Linda J and Russo, Giancarlo and Rubinsztein, David C and Tsolaki, Magda and Proitsi, Petra and Fox, Nick C and Hampel, Harald and Owen, Michael J and Mead, Simon and Morgan, Kevin and Schott, Jonathan M and Rossor, Martin and Lupton, Michelle K and Hoffmann, Per and Kornhuber, Johannes and McQuillin, Andrew and Al-Chalabi, Ammar and Bis, Joshua C and Ruiz, Agustin and Boada, Mercè and Seshadri, Sudha and Beiser, Alexa and Rice, Kenneth and De Jager, Philip L and Geschwind, Daniel H and Riemenschneider, Matthias and Riedel-Heller, Steffi and Rotter, Jerome I and Ransmayr, Gerhard and Hyman, Bradley T and Winsvold, Bendik and Palta, Priit and Farh, Kai-How and Cuenca-Leon, Ester and Furlotte, Nicholas and Ligthart, Lannie and Terwindt, Gisela M and Freilinger, Tobias and Ran, Caroline and Borck, Guntram and Lehtimäki, Terho and Wedenoja, Juho and Buring, Julie E and Schürks, Markus and Hottenga, Jouke-Jan and Penninx, Brenda and Artto, Ville and Martin, Nicholas G and Montgomery, Grant W and Kurki, Mitja I and Hämäläinen, Eija and ... and The Brainstorm Consortium and Brainstorm Consortium
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2018, Volume 360, Issue 6395, pp. eaap8757 - 1313
Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We... 
ANOREXIA-NERVOSA | MULTIPLE-SCLEROSIS | DEFICIT HYPERACTIVITY DISORDER | LONG-TERM SURVIVAL | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | GENETIC CORRELATIONS | SUSCEPTIBILITY LOCI | BODY-MASS INDEX | BIPOLAR DISORDER | GENOME-WIDE ASSOCIATION | Genetic Variation | Mental Disorders - genetics | Genome-Wide Association Study | Phenotype | Brain Diseases - classification | Quantitative Trait, Heritable | Brain Diseases - diagnosis | Humans | Mental Disorders - classification | Risk Factors | Brain Diseases - genetics | Mental Disorders - diagnosis | Headache | Anorexia | Mental disorders | Disorders | Cognitive ability | Schizophrenia | Risk sharing | Bipolar disorder | Genomes | Posttraumatic stress disorder | Mental depression | Epidemiology | Risk factors | Consortia | Proteins | Heterogeneity | Biological effects | Ischemia | Etiology | Risk assessment | Classification | Gilles de la Tourette syndrome | Alzheimer's disease | Neurological disorders | Stroke | Phenotypes | Neurodegenerative diseases | Comorbidity | Migraine | Attention deficit hyperactivity disorder | Eating disorders | Personality | Genetic diversity | Behavior disorders | Anorexia nervosa | Risk analysis | Patients | Statistics | Activity patterns | Neurological diseases | Crohn's Disease | Population (statistical) | Scaffolding | Correlation analysis | Heritability | Diagnostic systems | Alzheimers disease | Life Sciences | Human health and pathology | Mental Disorders | Neurons and Cognition | Brain Diseases | Genetics
Journal Article
Neurogenetics, ISSN 1364-6745, 2/2005, Volume 6, Issue 1, pp. 55 - 56
... in sporadic Gilles de la Tourette syndrome Published online: 31 December 2004 # Springer-Verlag 2004 Keywords DYT-11 . Epsilon-sarcoglycan . Myoclonusdystonia . SGCE... 
SGCE | DYT-11 | Myoclonus-dystonia | Epsilon-sarcoglycan | Tourette syndrome | GENE | epsilon-sarcoglycan | GENETICS & HEREDITY | MUTATIONS | myoclonus-dystonia | CLINICAL NEUROLOGY | Tourette Syndrome - genetics | Sarcoglycans - genetics | DNA Mutational Analysis | Humans
Journal Article
2014, ISBN 111851002X, Volume 9781118510025, xx, 409 pages
Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have... 
chemistry | Chemistry, Inorganic | Biochemical Phenomena | Biology, life sciences | Metals | Macromolecular Substances | Metals - chemistry | Bioinorganic chemistry | Organometallic chemistry | Metal complexes
Book
Chemical Society reviews, ISSN 0306-0012, 01/2017, Volume 46, Issue 23, pp. 7317 - 7337
Due to the increasing impact of cancer on worldwide mortality, more and more attention is being devoted to the investigation of novel anticancer strategies.... 
Organic chemistry | Chemotherapy | Ruthenium | Target recognition | Cell death | Toxicity | Cytotoxicity | Ligands | Chemical properties | Coordination compounds | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
Journal Article
Synlett, ISSN 0936-5214, 02/2015, Volume 26, Issue 3, pp. 275 - 284
Abstract The clinical success of cisplatin continues to inspire the development of metal-based anticancer drug candidates. This article is meant to present the... 
synpacts | ruthenium | drugs | photochemistry | carbonyl complexes | medicinal chemistry | antitumor agents
Journal Article
Current Opinion in Chemical Biology, ISSN 1367-5931, 04/2012, Volume 16, Issue 1-2, pp. 84 - 91
► Organometallic complexes have a huge potential in medicinal chemistry. ► Organometallic compounds have specific advantages over purely organic compounds. ►... 
BIOLOGICAL EVALUATION | IN-VITRO | BIOPHYSICS | FERROCENE | SELECTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | Oxidation-Reduction | Humans | Drug Design | Ligands | Organometallic Compounds - chemistry | Catalysis | Binding Sites
Journal Article
Chemical communications (Cambridge, England), ISSN 1364-548X, 2018, Volume 54, Issue 93, pp. 13040 - 13059
... 0 Marta Jakubaszek, ab Bruno Goud, b Stefano Ferrari c and Gilles Gasser * a The unique photophysical properties of Ru(II) polypyridyl complexes make them very... 
RUTHENIUM(II) COMPLEXES | IN-VITRO | PHOTODYNAMIC THERAPY | DNA | PHOTOSENSITIZERS | PORPHYRINS | CANCER | CYTOTOXICITY | BINDING | CHEMISTRY, MULTIDISCIPLINARY | Light irradiation | Photodynamic therapy | Medicinal Chemistry | Chemical Sciences
Journal Article
Chemical science (Cambridge), ISSN 2041-6539, 2015, Volume 6, Issue 5, pp. 2660 - 2686
... b and Gilles Gasser * a The synergistic action of light, oxygen and a photosensitizer (PS) has found applications for decades in medicine under the name... 
POLYPYRIDYL COMPLEXES | DNA PHOTOCLEAVAGE | PLATINUM COMPLEX | PHOTODYNAMIC THERAPY | POTENTIAL APPLICATION | RUTHENIUM-PORPHYRIN | BIOLOGICAL-ACTIVITIES | ANTICANCER COMPLEXES | CHEMISTRY, MULTIDISCIPLINARY | METAL-COMPLEXES | CELLULAR UPTAKE | Names | Chemotherapy | Photodynamic therapy | Toxicity | Medical services | Strategy | Tumors | Cancer | Chemistry
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 2015, Volume 54, Issue 47, pp. 14049 - 14052
Photodynamic therapy (PDT) is a noninvasive medical technique that has received increasing attention over the last years and been applied for the treatment of... 
cancer therapy | ruthenium | lysosomes | singlet oxygen | photodynamic therapy | CELLS | EXCITATION | CANCER | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | EXCITED-STATES | PROBES | LIGANDS | DNA | CHROMOPHORES | SINGLET OXYGEN GENERATION | Photochemotherapy | Ruthenium | Cancer | Lasers | Photodynamic therapy
Journal Article