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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 03/2019, Volume 20, Issue 5, p. 1110
Histone acetyltransferases (HATs) and histone deacetylases (HDACs) counteract with each other to regulate gene expression by altering chromatin structure.... 
HDACs | ACTIVATED PROTEIN-KINASE | SUBEROYLANILIDE HYDROXAMIC ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | HDAC INHIBITION | HDAC inhibitors | VORINOSTAT SAHA | human diseases | TNF-ALPHA EXPRESSION | chemokines | CHEMISTRY, MULTIDISCIPLINARY | IN-VITRO | CARDIAC-HYPERTROPHY | GENE-EXPRESSION | cytokines | INFLAMMATORY CYTOKINES | NF-KAPPA-B
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 5, pp. 2687 - 2700
Background: IL-8 promotes angiogenesis and metastasis in ovarian cancer. Results: Proteasome inhibition induces specific recruitment of IKK, EGR-1, and... 
Transcription Regulation | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Egr-1 | ALPHA | DRUG-RESISTANCE | BORTEZOMIB | NF-B (NF-KB) | Interleukin-8 | INDEPENDENT PROSTATE-CANCER | NUCLEAR TRANSLOCATION | Ovarian Cancer | P65 SUBUNIT | Immunology | GENE-EXPRESSION | GROWTH-FACTOR | Chemokines | Chromatin Immunoprecipitation (ChIP) | Proteasome | Interleukin-8 - genetics | Promoter Regions, Genetic - radiation effects | Humans | Ovarian Neoplasms - pathology | Multiple Myeloma - immunology | Chemokine CXCL5 - metabolism | Promoter Regions, Genetic - drug effects | Cell Nucleus - metabolism | I-kappa B Kinase - metabolism | Female | Antineoplastic Agents - pharmacology | Chemokine CCL2 - metabolism | Ovarian Neoplasms - metabolism | Interleukin-8 - metabolism | Bortezomib | Proteasome Inhibitors - pharmacology | Gene Expression Regulation, Leukemic - drug effects | Chemokine CCL2 - genetics | Multiple Myeloma - metabolism | Chemokine CXCL5 - genetics | Multiple Myeloma - pathology | Transcription Factor RelA - metabolism | Cell Line, Tumor | Promoter Regions, Genetic - immunology | Proteasome Endopeptidase Complex - metabolism | Pyrazines - pharmacology | Early Growth Response Protein 1 - metabolism | Boronic Acids - pharmacology | Gene Expression Regulation, Leukemic - immunology | Ovarian Neoplasms - immunology | NF-κB (NF-KB)
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 28, pp. 26347 - 26358
Ovarian cancer is associated with increased expression of the pro-angiogenic chemokine interleukin-8 (IL-8, CXCL8), which induces tumor cell proliferation,... 
IKK | bortezomib | Interleukin-8 | Proteasome inhibition | Ovarian cancer | SIGNALING PATHWAYS | CARCINOMA CELLS | ovarian cancer | INDUCED APOPTOSIS | PACLITAXEL RESISTANCE | DRUG-RESISTANCE | interleukin-8 | MULTIPLE-MYELOMA CELLS | KINASE-BETA | CELL BIOLOGY | proteasome inhibition | PHASE-I TRIAL | NF-KAPPA-B
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 9/2013, Volume 191, Issue 5, pp. 2837 - 2846
Expression of the pro-inflammatory and pro-angiogenic chemokine interleukin-8 (IL-8), which is regulated at the transcriptional level by NFκB, is... 
proteasome inhibition | prostate cancer | NFκB | bortezomib | Interleukin-8 | IκB kinase
Journal Article
01/2017, ISBN 0355353954
Overexpression of the pro-angiogenic chemokine IL-8 (CXCL8) is associated with a poor prognosis in several solid tumors, including epithelial ovarian cancer... 
Oncology | Molecular biology | Obstetrics
Dissertation
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