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1. Full Text Adoptive T cell transfer: Imagining the next generation of cancer immunotherapies
by Gattinoni, Luca
Seminars in Immunology, ISSN 1044-5323, 2016, Volume 28, Issue 1, pp. 1 - 2
Allergy and Immunology | Neoantigens | Stem cell-like T cells | MicroRNA therapeutics | Tumor microenvironment | TCR engineered T cells | T cell differentiation | T cell reprogramming | Cancer immunotherapy | Adoptive T cell transfer | CAR engineered T cells | T-Lymphocytes - immunology | Neoplasms - therapy | Immunotherapy, Adoptive | Neoplasms - immunology | Humans | Care and treatment | Drug therapy | T cells | Immunotherapy | Cancer | neoantigens | stem cell-like T cells | microRNA therapeutics | tumor microenvironment | adoptive T cell transfer
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2. Full Text Memory T Cells Officially Join the Stem Cell Club
by Gattinoni, Luca
Immunity, ISSN 1074-7613, 07/2014, Volume 41, Issue 1, pp. 7 - 9
In this issue of , demonstrate self-renewal and multipotency of a single CD62L memory T cell across serial adoptive transfers and infection-driven... 
IMMUNOLOGY | Animals | CD8-Positive T-Lymphocytes - immunology | Immunologic Memory - immunology | Cell Lineage - immunology | T cells | Stem cells | Studies | Antigens | Lymphocytes | Immunotherapy | Clinical trials | Homeostasis | T cell receptors
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3. Full Text Paths to stemness: Building the ultimate antitumour T cell
by Gattinoni, Luca and Klebanoff, Christopher A and Restifo, Nicholas P
Nature Reviews Cancer, ISSN 1474-175X, 10/2012, Volume 12, Issue 10, pp. 671 - 684
Stem cells are defined by the ability to self-renew and to generate differentiated progeny, qualities that are maintained by evolutionarily conserved pathways... 
TUMOR-INFILTRATING LYMPHOCYTES | LONG-TERM | TRANSCRIPTION FACTORS | ADOPTIVE TRANSFER | ONCOLOGY | CENTRAL MEMORY | EFFECTOR DIFFERENTIATION | DIRECT CONVERSION | SELF-RENEWAL | BETA-CATENIN | CUTTING EDGE | Hematopoietic Stem Cells - immunology | Neoplasms - therapy | Signal Transduction | Neoplasms - immunology | Humans | Hematopoietic Stem Cell Transplantation | Immunologic Memory | T-Lymphocytes - immunology | Cell Differentiation | Adoptive Transfer | T-Lymphocytes - transplantation | Care and treatment | Stem cells | Cellular therapy | Research | Properties | T cells | Health aspects | Tumors
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4. Full Text The dark side of T memory stem cells
by Gattinoni, Luca
Blood, ISSN 0006-4971, 06/2015, Volume 125, Issue 23, pp. 3519 - 3520
In this issue of Blood, Nagai et al provide evidence that adult T-cell leukemia is hierarchically organized and sustained by a small population of transformed... 
HEMATOLOGY | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - immunology | Animals | Cell Proliferation | Humans | Female | Immunologic Memory | Male | Human T-lymphotropic virus 1 - immunology | Leukemia-Lymphoma, Adult T-Cell - immunology | Inside
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5. Full Text T memory stem cells in health and disease
by Gattinoni, Luca and Speiser, Daniel E and Lichterfeld, Mathias and Bonini, Chiara
Nature Medicine, ISSN 1078-8956, 2017, Volume 23, Issue 1, pp. 18 - 27
T memory stem (TscM) cells are a rare subset of memory lymphocytes endowed with the stem cell like ability to self-renew and the multipotent capacity to... 
MEDICINE, RESEARCH & EXPERIMENTAL | LINEAGE RELATIONSHIP | BIOCHEMISTRY & MOLECULAR BIOLOGY | BONE-MARROW | SELF-RENEWAL | ANTIRETROVIRAL THERAPY | ANTITUMOR-ACTIVITY | HOMEOSTATIC PROLIFERATION | YELLOW-FEVER | CUTTING EDGE | CELL BIOLOGY | PROTECTIVE IMMUNITY | B-CELL | Cell Self Renewal - immunology | Stem Cells - immunology | Leukemia, T-Cell - immunology | Humans | Autoimmune Diseases - immunology | Adoptive Transfer | T-Lymphocytes - transplantation | HIV Infections - immunology | Animals | Autoimmune Diseases - therapy | HIV Infections - therapy | T-Lymphocytes - immunology | Cell Differentiation | Leukemia, T-Cell - therapy | Immunologic Memory - immunology | Medical research | Immune response | Stem cells | Medicine, Experimental | Research | T cells | Health aspects | Autoimmunity | Communicable diseases | Leukemia | B cells | HIV (Viruses) | Adult T cell leukemia | Immunological memory | Memory cells | Stem cell transplantation | Immune reconstitution | Lymphocytes T | Vaccines | Computer memory | Infectious diseases | Allografts | Lymphocytes | Human immunodeficiency virus--HIV | Primates | Autoimmune diseases | Cancer
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6. Full Text A human memory T cell subset with stem cell-like properties
by Gattinoni, Luca and Lugli, Enrico and Ji, Yun and Pos, Zoltan and Paulos, Chrystal M and Quigley, Máire F and Almeida, Jorge R and Gostick, Emma and Yu, Zhiya and Carpenito, Carmine and Wang, Ena and Douek, Daniel C and Price, David A and June, Carl H and Marincola, Francesco M and Roederer, Mario and Restifo, Nicholas P
Nature Medicine, ISSN 1078-8956, 10/2011, Volume 17, Issue 10, pp. 1290 - 1297
Immunological memory is thought to depend on a stem cell-like, self-renewing population of lymphocytes capable of differentiating into effector cells in... 
MEDICINE, RESEARCH & EXPERIMENTAL | LYMPHOCYTE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHENOTYPE | NAIVE RATHER | BETA-CATENIN | CANCER | CELL BIOLOGY | SUPERIOR ANTITUMOR IMMUNITY | DIFFERENTIATION | TRANSCRIPTION FACTOR | EXPRESSION | ADOPTIVE IMMUNOTHERAPY | T-Lymphocyte Subsets - immunology | Receptors, Interleukin-7 - metabolism | Cell Proliferation | Leukocyte Common Antigens - metabolism | Humans | Gene Expression Profiling | CD28 Antigens - metabolism | L-Selectin - metabolism | Animals | Flow Cytometry | Analysis of Variance | Receptors, CCR7 - metabolism | T-Lymphocytes - cytology | T-Lymphocytes - metabolism | T-Lymphocyte Subsets - metabolism | Tumor Necrosis Factor Receptor Superfamily, Member 7 - metabolism | Immunologic Memory | T-Lymphocytes - immunology | Mice | Physiological aspects | Genetic aspects | Research | Immunologic memory | T cells | Antigens | T cell receptors | Immunology | Lymphocytes | Stem cells
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7. Full Text Adoptive immunotherapy for cancer: building on success
by Restifo, Nicholas P and Gattinoni, Luca and Powell, Daniel J and Rosenberg, Steven A
Nature Reviews Immunology, ISSN 1474-1733, 05/2006, Volume 6, Issue 5, pp. 383 - 393
Adoptive cell transfer after host preconditioning by lymphodepletion represents an important advance in cancer immunotherapy. Here, we describe how a... 
TUMOR-INFILTRATING LYMPHOCYTES | TOTAL-BODY IRRADIATION | METASTATIC MELANOMA | NATURAL-KILLER-CELLS | IN-VIVO PERSISTENCE | LONG-TERM SURVIVAL | ANTITUMOR IMMUNITY | IMMUNOLOGY | VERSUS-HOST-DISEASE | CD8(+) T-CELLS | TRANSFER THERAPY | Immunotherapy, Adoptive - methods | Neoplasms - therapy | Animals | T-Lymphocyte Subsets - transplantation | Neoplasms - immunology | Humans
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8. Full Text Wnt signaling arrests effector T cell differentiation and generates CD8 + memory stem cells
by Zhong, Xiao-Song and Gattinoni, Luca and Restifo, Nicholas P and Wrzesinski, Claudia and Ji, Yun and Palmer, Douglas C and Paulos, Chrystal M and Garvin, Lindsay M and Yu, Zhiya and Boni, Andrea and Cassard, Lydie and Muranski, Pawel and Hinrichs, Christian S
Nature Medicine, ISSN 1078-8956, 07/2009, Volume 15, Issue 7, pp. 808 - 813
Self-renewing cell populations such as hematopoietic stem cells and memory B and T lymphocytes might be regulated by shared signaling pathways. The... 
TRANSCRIPTION FACTORS | LONG-TERM | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF-RENEWAL | PROLIFERATION | BETA-CATENIN | CANCER | CELL BIOLOGY | MAINTENANCE | IN-VIVO | ADOPTIVE IMMUNOTHERAPY | CD8-Positive T-Lymphocytes - cytology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Lymphocyte Activation | Mice, Inbred C57BL | Hepatocyte Nuclear Factor 1-alpha | Glycogen Synthase Kinase 3 beta | L-Selectin - analysis | CD8-Positive T-Lymphocytes - physiology | Hyaluronan Receptors - analysis | T Cell Transcription Factor 1 - physiology | Animals | Hematopoietic Stem Cells - physiology | Immunologic Memory | Signal Transduction - physiology | Cell Differentiation | Mice | Wnt Proteins - physiology | beta Catenin - physiology | Signal transduction | Biomedical research | Immunology | Cellular biology | Stem cells
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9. Full Text Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries
by Bellani, Giacomo and Laffey, John G and Pham, Tài and Fan, Eddy and Brochard, Laurent and Esteban, Andres and Gattinoni, Luciano and van Haren, Frank and Larsson, Anders and McAuley, Daniel F and Ranieri, Marco and Rubenfeld, Gordon and Thompson, B. Taylor and Wrigge, Hermann and Slutsky, Arthur S and Pesenti, Antonio and LUNG SAFE Investigators & ESICM and LUNG SAFE Investigators and ESICM Trials Group and for the LUNG SAFE Investigators and the ESICM Trials Group and Medicinska fakulteten and Anestesiologi och intensivvård and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för kirurgiska vetenskaper and Hedenstiernalaboratoriet
JAMA, ISSN 0098-7484, 02/2016, Volume 315, Issue 8, pp. 788 - 800
IMPORTANCE: Limited information exists about the epidemiology, recognition, management, and outcomes of patients with the acute respiratory distress syndrome... 
PRESSURE | MEDICINE, GENERAL & INTERNAL | UNDERRECOGNITION | STATES | BERLIN DEFINITION | VENTILATION | ACUTE LUNG INJURY | CLINICIAN | UNDERUSE | COHORT | Severity of Illness Index | Prone Position | Prevalence | Prospective Studies | Hospital Mortality | Neuromuscular Blockade - methods | Patient Positioning | Humans | Middle Aged | Intensive Care Units - statistics & numerical data | Male | Treatment Outcome | Positive-Pressure Respiration - statistics & numerical data | Positive-Pressure Respiration - methods | Respiratory Distress Syndrome, Adult - mortality | Respiratory Distress Syndrome, Adult - diagnosis | Incidence | Neuromuscular Blockade - statistics & numerical data | Algorithms | Global Health - statistics & numerical data | Female | Organ Dysfunction Scores | Respiratory Distress Syndrome, Adult - epidemiology | Respiratory Distress Syndrome, Adult - therapy | Acute respiratory distress syndrome | Intensive care units | Care and treatment | Patient outcomes | Analysis | Management | Epidemiology | Risk factors | Global health | Intensive care | Respiratory distress syndrome | Mortality | Clinical outcomes | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Anestesi och intensivvård | Anesthesiology and Intensive Care | Lungmedicin och allergi | Klinisk medicin | Respiratory Medicine and Allergy
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