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adolescent (57) 57
child, preschool (57) 57
pediatrics (49) 49
mutation (48) 48
familial mediterranean fever (42) 42
children (41) 41
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autoinflammatory diseases (33) 33
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fever (28) 28
arthritis (25) 25
infant (25) 25
juvenile idiopathic arthritis (25) 25
rheumatoid-arthritis (25) 25
diagnosis (24) 24
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patients (24) 24
cytokines (23) 23
phenotype (23) 23
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immunology and allergy (20) 20
poster presentation (20) 20
risk factors (20) 20
care and treatment (18) 18
pediatrics, perinatology, and child health (18) 18
treatment outcome (18) 18
anakinra (17) 17
diseases of the musculoskeletal system (16) 16
health aspects (16) 16
analysis (15) 15
case-control studies (15) 15
cells, cultured (15) 15
diseases (15) 15
familial mediterranean fever - genetics (15) 15
severity of illness index (15) 15
familial mediterranean fever - diagnosis (14) 14
hyperimmunoglobulinemia-d (14) 14
lymphocytes (14) 14
follow-up studies (13) 13
activation (12) 12
arthritis, juvenile - immunology (12) 12
hereditary autoinflammatory diseases - genetics (12) 12
middle aged (12) 12
monocytes (12) 12
periodic fever (12) 12
proteins (12) 12
syndrome (12) 12
treatment (12) 12
dendritic cells (11) 11
genetic aspects (11) 11
hereditary autoinflammatory diseases - diagnosis (11) 11
internal medicine (11) 11
animals (10) 10
aphthous stomatitis (10) 10
arthritis, juvenile - blood (10) 10
autoimmune diseases (10) 10
cias1 mutations (10) 10
cryopyrin (10) 10
cryopyrin-associated periodic syndromes - genetics (10) 10
diagnosis, differential (10) 10
gene (10) 10
interleukin-1 receptor antagonist (10) 10
registries (10) 10
systemic-lupus-erythematosus (10) 10
usage (10) 10
arthritis, juvenile - pathology (9) 9
biomarkers - blood (9) 9
classification (9) 9
cohort studies (9) 9
colchicine (9) 9
criteria (9) 9
cryopyrin-associated periodic syndromes (9) 9
fever syndromes (9) 9
gene expression (9) 9
genotype (9) 9
interleukin 1 receptor antagonist protein - therapeutic use (9) 9
management (9) 9
medicine (9) 9
mevalonate kinase deficiency (9) 9
oxidative stress (9) 9
recurrence (9) 9
retrospective studies (9) 9
age of onset (8) 8
antirheumatic agents - therapeutic use (8) 8
autoimmunity (8) 8
cells (8) 8
cryopyrin-associated periodic syndromes - diagnosis (8) 8
efficacy (8) 8
expression (8) 8
genotype & phenotype (8) 8
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1. Familial Mediterranean Fever
by Gattorno, Marco and SpringerLink (Online service)
2015, Rare Diseases of the Immune System, ISBN 9783319146157, Volume 3
This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic... 
Medicine | Immunology | Internal medicine | Rheumatology | Human genetics
Web Resource
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2. Familial Mediterranean Fever
by Gattorno, Marco and SpringerLink (Online service)
2015, Rare Diseases of the Immune System, ISBN 9783319146157, Volume 3
This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic... 
Medicine | Immunology | Internal medicine | Rheumatology | Human genetics
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3. Full Text Canakinumab treatment for patients with active recurrent or chronic TNF receptor-associated periodic syndrome (TRAPS): an open-label, phase II study
by Gattorno, Marco and Obici, Laura and Cattalini, Marco and Tormey, Vincent and Abrams, Ken and Davis, Nicole and Speziale, Antonio and Bhansali, Suraj G and Martini, Alberto and Lachmann, Helen J
Annals of the Rheumatic Diseases, ISSN 0003-4967, 01/2017, Volume 76, Issue 1, pp. 173 - 178
ObjectiveTo evaluate the efficacy of canakinumab, a high-affinity human monoclonal anti-interleukin-1β antibody, in inducing complete or almost complete... 
SUSTAINED RESPONSE | EFFICACY | AUTOINFLAMMATORY DISEASES | ANAKINRA | RHEUMATOLOGY | ETANERCEPT | REGISTRY | Recurrence | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Antibodies, Monoclonal - blood | Young Adult | Adult | Female | Child | Receptors, Tumor Necrosis Factor - genetics | Severity of Illness Index | Drug Administration Schedule | Familial Mediterranean Fever - genetics | Immunologic Factors - administration & dosage | Immunologic Factors - blood | Treatment Outcome | Familial Mediterranean Fever - drug therapy | Antibodies, Monoclonal - administration & dosage | Adolescent | Quality of Life | Aged | Chronic Disease | Immunologic Factors - therapeutic use | Treatment outcome | Control | Analysis | Diseases | Index Medicus | Clinical and Epidemiological Research | Treatment | Cytokines | TNF-alpha | 1506 | Fever Syndromes
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4. Full Text A practical approach to the diagnosis of autoinflammatory diseases in childhood
by Federici, Silvia and Gattorno, Marco
Best Practice and Research: Clinical Rheumatology, ISSN 1521-6942, 2014, Volume 28, Issue 2, pp. 263 - 276
Autoinflammatory diseases are characterized by the presence of chronic or recurrent systemic inflammation secondary to abnormal activation of innate immunity... 
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5. Full Text Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes
by De Benedetti, Fabrizio and Gattorno, Marco and Anton, Jordi and Ben-Chetrit, Eldad and Frenkel, Joost and Hoffman, Hal M and Koné-Paut, Isabelle and Lachmann, Helen J and Ozen, Seza and Simon, Anna and Zeft, Andrew and Calvo Penades, Inmaculada and Moutschen, Michel and Quartier, Pierre and Kasapcopur, Ozgur and Shcherbina, Anna and Hofer, Michael and Hashkes, Philip J and Van der Hilst, Jeroen and Hara, Ryoki and Bujan-Rivas, Segundo and Constantin, Tamas and Gul, Ahmet and Livneh, Avi and Brogan, Paul and Cattalini, Marco and Obici, Laura and Lheritier, Karine and Speziale, Antonio and Junge, Guido
The New England Journal of Medicine, ISSN 0028-4793, 05/2018, Volume 378, Issue 20, pp. 1908 - 1919
The anti–interleukin-1 antibody canakinumab was effective at controlling and preventing recurrence of flares in autoimmune inflammatory diseases: familial... 
MEDICINE, GENERAL & INTERNAL | FAMILIAL MEDITERRANEAN FEVER | INFLAMMATION | HYPERIMMUNOGLOBULINEMIA-D | INTERLEUKIN-1-BETA SECRETION | PHASE-II | OPEN-LABEL | ANAKINRA | COLCHICINE-RESISTANT | PERIODIC SYNDROME TRAPS | AA AMYLOIDOSIS | Prevention | Treatment outcome | Fever in children | Diagnosis | Analysis | Pediatrics | Writers | Cytokines | Internal medicine | Laboratories | Rheumatology | Disease control | Patients | Fever | Medicine | Mevalonate kinase | Infectious diseases | Mevalonic acid | Immunology | Hospitals | Familial Mediterranean fever | Mutation | Colchicine | Drug dosages | University colleges | Index Medicus | Abridged Index Medicus
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6. Full Text Dependence of Immunoglobulin Class Switch Recombination in B Cells on Vesicular Release of ATP and CD73 Ectonucleotidase Activity
by Schena, Francesca and Volpi, Stefano and Faliti, Caterina Elisa and Penco, Federica and Santi, Spartaco and Proietti, Michele and Schenk, Ursula and Damonte, Gianluca and Salis, Annalisa and Bellotti, Marta and Fais, Franco and Tenca, Claudya and Gattorno, Marco and Eibel, Hermann and Rizzi, Marta and Warnatz, Klaus and Idzko, Marco and Ayata, Cemil Korcan and Rakhmanov, Mirzokhid and Galli, Thierry and Martini, Alberto and Canossa, Marco and Grassi, Fabio and Traggiai, Elisabetta
Cell Reports, ISSN 2211-1247, 06/2013, Volume 3, Issue 6, pp. 1824 - 1831
Immunoglobulin (Ig) isotype diversification by class switch recombination (CSR) is an essential process for mounting a protective humoral immune response. Ig... 
TI-VAMP/VAMP7 | IMMUNITY | DEFECTS | COMMON VARIABLE IMMUNODEFICIENCY | RECEPTOR | ASTROCYTES | SUBSET | DEFICIENCY | LYMPHOCYTES | CELL BIOLOGY | 5'-Nucleotidase - genetics | Antigens, CD - immunology | Common Variable Immunodeficiency - immunology | Humans | Immunoglobulin Class Switching - immunology | B-Lymphocyte Subsets - cytology | Adenosine Triphosphate - genetics | Antigens, CD - metabolism | Recombination, Genetic | Adenosine Triphosphate - metabolism | 5'-Nucleotidase - immunology | B-Lymphocyte Subsets - immunology | B-Lymphocytes - metabolism | Antibody Formation - immunology | B-Lymphocytes - cytology | Apyrase - metabolism | Apyrase - immunology | Adenosine Triphosphate - immunology | Common Variable Immunodeficiency - genetics | Mice, Transgenic | Animals | B-Lymphocytes - immunology | Common Variable Immunodeficiency - metabolism | Mice | 5'-Nucleotidase - metabolism | Antibody Formation - genetics | Index Medicus
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7. Full Text The Phenotype and Genotype of Mevalonate Kinase Deficiency: A Series of 114 Cases From the Eurofever Registry
by Haar, N. Ter and Jeyaratnam, J and Lachmann, H.J and Simon, A and Brogan, P.A and Doglio, M and Cattalini, M and Anton, J and Modesto, C and Quartier, P and Hoppenreijs, E.P and Martino, S and Insalaco, A and Cantarini, L and Lepore, L and Alessio, M and Calvo Penades, I and Boros, C and Consolini, R and Rigante, D and Russo, R and Pachlopnik Schmid, J and Lane, T and Martini, A and Ruperto, N and Frenkel, J and Gattorno, M and Paediat Rheumatology Int Trials and Paediatric Rheumatology International Trials Organisation and Eurofever Project
Arthritis & Rheumatology, ISSN 2326-5191, 2016, Volume 68, Issue 11, pp. 2795 - 2805
ObjectiveMevalonate kinase deficiency (MKD) is a rare metabolic disease characterized by recurrent inflammatory episodes. This study was undertaken to describe... 
MVK | HYPER-IGD | PERIODIC FEVER SYNDROME | ACIDURIA | HYPERIMMUNOGLOBULINEMIA-D | AUTOINFLAMMATORY DISEASES | MUTATIONS | SPECTRUM | RHEUMATOLOGY | Arthralgia - etiology | Uveitis - etiology | Humans | Child, Preschool | Lymphadenopathy - etiology | Male | Arthralgia - physiopathology | Arthritis - genetics | Stomatitis, Aphthous - genetics | Cerebellar Diseases - physiopathology | Amyloidosis - genetics | Skin Diseases - physiopathology | Amyloidosis - etiology | Child | Stomatitis, Aphthous - etiology | Infant, Newborn | Myalgia - physiopathology | Amyloidosis - physiopathology | Genotype | Headache - physiopathology | Vomiting - genetics | Phenotype | Diarrhea - genetics | Abdominal Pain - genetics | Adolescent | Age of Onset | Intellectual Disability - etiology | Uveitis - genetics | Vomiting - physiopathology | Conjunctivitis - etiology | Conjunctivitis - genetics | Arthritis - physiopathology | Headache - etiology | Skin Diseases - genetics | Mevalonate Kinase Deficiency - physiopathology | Myalgia - genetics | Cerebellar Diseases - etiology | Diarrhea - physiopathology | Infant | Mevalonate Kinase Deficiency - genetics | Intellectual Disability - genetics | Pharyngitis - genetics | Arthritis - etiology | Female | Registries | Retrospective Studies | Arthralgia - genetics | Pharyngitis - physiopathology | Abdominal Pain - etiology | Pharyngitis - etiology | Lymphadenopathy - genetics | Abdominal Pain - physiopathology | Myalgia - etiology | Phosphotransferases (Alcohol Group Acceptor) - genetics | Headache - genetics | Intellectual Disability - physiopathology | Skin Diseases - etiology | Cerebellar Diseases - genetics | Conjunctivitis - physiopathology | Mevalonate Kinase Deficiency - complications | Stomatitis, Aphthous - physiopathology | Vomiting - etiology | Diarrhea - etiology | Lymphadenopathy - physiopathology | Uveitis - physiopathology | Kinases | Genotype & phenotype | Index Medicus | Abridged Index Medicus
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8. Full Text Canakinumab reverses overexpression of inflammatory response genes in tumour necrosis factor receptor-associated periodic syndrome
by Torene, Rebecca and Nirmala, Nanguneri and Obici, Laura and Cattalini, Marco and Tormey, Vincent and Caorsi, Roberta and Starck-Schwertz, Sandrine and Letzkus, Martin and Hartmann, Nicole and Abrams, Ken and Lachmann, Helen and Gattorno, Marco
Annals of the Rheumatic Diseases, ISSN 0003-4967, 01/2017, Volume 76, Issue 1, pp. 303 - 309
ObjectiveTo explore whether gene expression profiling can identify a molecular mechanism for the clinical benefit of canakinumab treatment in patents with... 
TNF RECEPTOR | INTERLEUKIN-1 | ACTIVATION | SYNDROME TRAPS | IL-1 | IN-VIVO | AUTOINFLAMMATORY DISEASES | FEVER SYNDROME | MUTATIONS | ANAKINRA | RHEUMATOLOGY | Genetic Predisposition to Disease | Drug Administration Schedule | Antibodies, Monoclonal - pharmacology | Humans | Middle Aged | Neutrophils - drug effects | Familial Mediterranean Fever - genetics | Antibodies, Monoclonal - therapeutic use | Familial Mediterranean Fever - metabolism | Gene Expression Profiling - methods | Male | Familial Mediterranean Fever - drug therapy | Gene Expression Regulation - drug effects | Young Adult | Antibodies, Monoclonal - administration & dosage | Adolescent | Receptors, Tumor Necrosis Factor - biosynthesis | Adult | Female | Aged | Leukocyte Count | Child | Interleukin-1beta - antagonists & inhibitors | Receptors, Tumor Necrosis Factor - genetics | Care and treatment | Research | Gene expression | Tumor necrosis factor | Index Medicus | Basic and Translational Research | Inflammation | Cytokines | 1506 | Fever Syndromes
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9. Full Text Differentiating PFAPA Syndrome From Monogenic Periodic Fevers
by Gattorno, Marco and Caorsi, Roberta and Meini, Antonella and Cattalini, Marco and Federici, Silvia and Zulian, Francesco and Cortis, Elisabetta and Calcagno, Giuseppina and Tommasini, Alberto and Consolini, Rita and Simonini, Gabriele and Pelagatti, Maria Antonietta and Baldi, Maurizia and Ceccherini, Isabella and Plebani, Alessandro and Frenkel, Joost and Sormani, Maria Pia and Martini, Alberto
Pediatrics, ISSN 0031-4005, 10/2009, Volume 124, Issue 4, pp. e721 - e728
OBJECTIVES: To analyze whether there were clinical differences between genetically positive and negative patients fulfilling periodic fever, aphthous... 
Aphthous stomatitis | Diagnostic score | Periodic fever | Classification | And cervical adenitis syndrome | Molecular analysis | Pharyngitis | DIAGNOSIS | pharyngitis | diagnostic score | RECEPTOR | CLINICAL-FEATURES | classification | ENCODING MEVALONATE KINASE | aphthous stomatitis | AUTOINFLAMMATORY DISORDERS | and cervical adenitis syndrome | HYPERIMMUNOGLOBULINEMIA-D | PEDIATRICS | MUTATIONS | periodic fever | molecular analysis | HYPER-IGD SYNDROME | Fever of Unknown Origin - genetics | Diagnosis, Differential | Genetic Predisposition to Disease | Humans | Familial Mediterranean Fever - genetics | Gene Expression Regulation | Child, Preschool | Male | Phosphotransferases (Alcohol Group Acceptor) - genetics | Lymphadenitis - genetics | Syndrome | Pharyngitis - genetics | Pharyngitis - diagnosis | Stomatitis, Aphthous - diagnosis | Stomatitis, Aphthous - genetics | Lymphadenitis - diagnosis | Female | Familial Mediterranean Fever - diagnosis | Mutation | Child | Fever of Unknown Origin - diagnosis | Cohort Studies | Receptors, Tumor Necrosis Factor - genetics | Pediatrics | Genotype & phenotype | Genetic testing | Fever | Index Medicus | Abridged Index Medicus
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10. Full Text Follow-Up and Quality of Life of Patients with Cryopyrin-Associated Periodic Syndromes Treated with Anakinra
by Lepore, Loredana, MD and Paloni, Giulia, MD and Caorsi, Roberta, MD and Alessio, Maria, MD and Rigante, Donato, MD and Ruperto, Nicola, MD and Cattalini, Marco, MD and Tommasini, Alberto, MD and Zulian, Francesco, MD and Ventura, Alessando, MD and Martini, Alberto, MD and Gattorno, Marco, MD
Journal of Pediatrics, The, ISSN 0022-3476, 2010, Volume 157, Issue 2, pp. 310 - 315.e1
Objective To evaluate the quality of life and long-term follow-up of patients enrolled in the Italian registry of cryopyrin-associated periodic syndromes... 
Pediatrics | PEDIATRICS | MUCKLE-WELLS-SYNDROME | ANTAGONIST | DISEASES | COLD AUTOINFLAMMATORY SYNDROME | CIAS1 MUTATIONS | Follow-Up Studies | Humans | Child, Preschool | Male | Treatment Outcome | Inflammation | Cryopyrin-Associated Periodic Syndromes - drug therapy | Case-Control Studies | Syndrome | Cryopyrin-Associated Periodic Syndromes - physiopathology | Phenotype | Interleukin 1 Receptor Antagonist Protein - therapeutic use | Adolescent | Quality of Life | Adult | Female | Surveys and Questionnaires | Interleukin-1 - antagonists & inhibitors | Child | Quality of Health Care | Health aspects | Children | Index Medicus | Abridged Index Medicus
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11. Full Text Familial Mediterranean Fever
by Gattorno, Marco
03/2015, Rare Diseases of the Immune System, ISBN 3319146149, Volume 3, 166
This book, written by very well known opinion leaders in the field, covers all aspects of familial Mediterranean fever, the most common monogenic... 
Periodic peritonitis
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12. Full Text Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
by Jarrossay, David and Acosta-Rodriguez, Eva V and Sallusto, Federica and Gattorno, Marco and Napolitani, Giorgio and Lanzavecchia, Antonio and Geginat, Jens and Rivino, Laura
Nature Immunology, ISSN 1529-2908, 06/2007, Volume 8, Issue 6, pp. 639 - 646
Interleukin 17 (IL-17)-producing T helper cells (TH-17 cells) have been characterized in mice as a distinct subset of effector cells, but their identity and... 
CHEMOKINE RECEPTOR EXPRESSION | MYCOBACTERIUM-TUBERCULOSIS | HUMAN AIRWAY EPITHELIUM | AUTOIMMUNE INFLAMMATION | DENDRITIC CELLS | IMMUNE-RESPONSES | IL-17 | INFLAMMATORY PROTEIN 3-ALPHA | IMMUNOLOGY | UP-REGULATION | CUTTING EDGE | Nuclear Receptor Subfamily 1, Group F, Member 3 | T-Lymphocytes, Helper-Inducer - metabolism | Humans | RNA, Messenger - genetics | Receptors, Chemokine - metabolism | Cells, Cultured | Gene Expression Regulation | Interleukin-17 - biosynthesis | Candida albicans - immunology | Receptors, Retinoic Acid - genetics | Phenotype | Animals | Receptors, Thyroid Hormone - genetics | T-Lymphocytes, Helper-Inducer - immunology | Interleukin-23 - biosynthesis | Antigens - immunology | Receptors, CCR6 | Mice | Receptors, CCR4 | Receptors, CXCR3 | Immunologic Memory - immunology | Interleukins | CD4 lymphocytes | Physiological aspects | Research | DNA binding proteins | Properties | Health aspects | Index Medicus
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13. Full Text Clinical impact of MEFV mutations in children with periodic fever in a prevalent western European Caucasian population
by Federici, Silvia and Calcagno, Giuseppina and Finetti, Martina and Gallizzi, Romina and Meini, Antonella and Vitale, Agata and Caroli, Francesco and Cattalini, Marco and Caorsi, Roberta and Zulian, Francesco and Tommasini, Alberto and Insalaco, Antonella and Sormani, Maria Pia and Baldi, Maurizia and Ceccherini, Isabella and Martini, Alberto and Gattorno, Marco
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2012, Volume 71, Issue 12, pp. 1961 - 1965
Objective To evaluate the actual impact of MEFV mutations on clinical manifestations associated with fever attacks in Caucasian children with periodic fever.... 
CRITERIA | DIAGNOSIS | PROTEIN | FAMILIAL MEDITERRANEAN FEVER | GENE | CASPASE-1 | DISEASE | DISORDERS | RHEUMATOLOGY | PYRIN | Gene Dosage - genetics | European Continental Ancestry Group - genetics | Prevalence | Cytoskeletal Proteins - genetics | Genes, Recessive - genetics | Humans | Familial Mediterranean Fever - genetics | Child, Preschool | Europe - epidemiology | Familial Mediterranean Fever - ethnology | European Continental Ancestry Group - statistics & numerical data | Exons - genetics | Infant | Male | Penetrance | Pyrin | Phenotype | Female | Child | Relapse | Control | Gene mutations | Hereditary autoinflammatory diseases | Causes of | Genetic aspects | Research | Children of minorities | Diseases | Proteins | Variables | Genotype & phenotype | Hypotheses | Pain | Cytokines | Genes | Families & family life | Mutation | Fever | Abdomen | Index Medicus
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14. Full Text Eurofever-lesons from last year
by Gattorno, Marco
Pediatric Rheumatology, ISSN 1546-0096, 09/2014, Volume 12, Issue S1, pp. I32 - I32
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15. Full Text The multifaceted presentation of chronic recurrent multifocal osteomyelitis: a series of 486 cases from the Eurofever international registry
by Girschick, Hermann and Finetti, Martina and Orlando, Francesca and Schalm, Susanne and Insalaco, Antonella and Ganser, Gerd and Nielsen, Susan and Herlin, Troels and Koné-Paut, Isabelle and Martino, Silvana and Cattalini, Marco and Anton, Jordi and Mohammed Al-Mayouf, Sulaiman and Hofer, Michael and Quartier, Pierre and Boros, Christina and Kuemmerle-Deschner, Jasmin and Pires Marafon, Denise and Alessio, Maria and Schwarz, Tobias and Ruperto, Nicolino and Martini, Alberto and Jansson, Annette and Gattorno, Marco and Eurofever Registry and Paediat Rheumatology Int Trials and Paediatric Rheumatology International Trials Organisation (PRINTO) and the Eurofever registry
Rheumatology, ISSN 1462-0324, 07/2018, Volume 57, Issue 7, pp. 1203 - 1211
Abstract Objectives Chronic non-bacterial osteomyelitis (CNO) or chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory disorder... 
Treatment | Magnetic resonance imaging | Bone inflammation | Palmoplantar pustulosis | Chronic non-bacterial osteomyelitis | Autoinflammatory diseases | SAPHO | Registry | Bisphosphonates | Chronic recurrent multifocal osteomyelitis | LONG-TERM | registry | treatment | bone inflammation | magnetic resonance imaging | HYPEROSTOSIS | autoinflammatory diseases | FOLLOW-UP | RHEUMATOLOGY | CHRONIC NONBACTERIAL OSTEOMYELITIS | AUTOINFLAMMATORY BONE DISORDERS | SAPHO SYNDROME | OSTEITIS | CRMO | CHILDREN | chronic non-bacterial osteomyelitis | chronic recurrent multifocal osteomyelitis | palmoplantar pustulosis | bisphosphonates | OUTCOMES | Glucocorticoids | Psoriasis | Interleukin 1 receptor antagonist | Acne | Exanthema | Pustulosis | Myalgia | Osteolysis | Nonsteroidal antiinflammatory drugs | Osteomyelitis | Tumor necrosis factor | Adults | Diagnosis | Age
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16. Full Text Altered redox state of monocytes from cryopyrin-associated periodic syndromes causes accelerated IL-1β secretion
by Sara Tassi and Sonia Carta and Laura Delfino and Roberta Caorsi and Alberto Martini and Marco Gattomo and Anna Rubartelli and Charles A. Dinarello
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2010, Volume 107, Issue 21, pp. 9789 - 9794
In healthy monocytes, Toll-like receptor (TLR) engagement induces production of reactive oxygen species (ROS), followed by an antioxidant response involved in... 
Antioxidants | Cryopyrin associated periodic syndromes | Oxidative stress | Monocytes | Reactive oxygen species | Nervous system diseases | Secretion | Chronic diseases | Kinetics | Genetic mutation | Autoinflammatory diseases | Inflammasome | Antioxidant response | Thioredoxin | OXIDATIVE STRESS | ACTIVATION | thioredoxin | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | autoinflammatory diseases | JUVENILE IDIOPATHIC ARTHRITIS | CIAS1 MUTATIONS | antioxidant response | inflammasome | reactive oxygen species | DISEASE | RESISTANCE | EXPRESSION | ATP | Biological Sciences
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