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1. Full Text Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity
by Gaublomme, Jellert T and Yosef, Nir and Lee, Youjin and Gertner, Rona S and Yang, Li V and Wu, Chuan and Pandolfi, Pier Paolo and Mak, Tak and Satija, Rahul and Shalek, Alex K and Kuchroo, Vijay K and Park, Hongkun and Regev, Aviv
Cell, ISSN 0092-8674, 12/2015, Volume 163, Issue 6, pp. 1400 - 1412
Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely... 
MOLECULAR SIGNATURE | T(H)17 CELLS | MULTIPLE-SCLEROSIS | RNA-SEQ | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF-RENEWAL | GENERATION | FLOW-CYTOMETRY | DIFFERENTIATION | IDENTIFICATION | T-CELLS | CELL BIOLOGY | Lymph Nodes - pathology | Encephalomyelitis, Autoimmune, Experimental - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Central Nervous System - pathology | Encephalomyelitis, Autoimmune, Experimental - immunology | Gene Expression Profiling | Th17 Cells - metabolism | Kruppel-Like Transcription Factors - metabolism | Membrane Proteins - metabolism | Single-Cell Analysis | Th17 Cells - pathology | Peptide Fragments - metabolism | Encephalomyelitis, Autoimmune, Experimental - pathology | Mice, Inbred C57BL | Promyelocytic Leukemia Zinc Finger Protein | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Animals | Carrier Proteins - metabolism | Myelin-Oligodendrocyte Glycoprotein - metabolism | Sequence Analysis, RNA | Th17 Cells - immunology | Mice | Receptors, Immunologic - metabolism | Autoimmunity | Computer science | Electrical engineering | RNA | Analysis | Genomics | Genetic research | Cells
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2. Full Text Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
by Shalek, Alex K and Satija, Rahul and Shuga, Joe and Trombetta, John J and Gennert, Dave and Lu, Diana and Chen, Peilin and Gertner, Rona S and Gaublomme, Jellert T and Yosef, Nir and Schwartz, Schraga and Fowler, Brian and Weaver, Suzanne and Wang, Jing and Wang, Xiaohui and Ding, Ruihua and Raychowdhury, Raktima and Friedman, Nir and Hacohen, Nir and Park, Hongkun and May, Andrew P and Regev, Aviv
Nature, ISSN 0028-0836, 2014, Volume 510, Issue 7505, pp. 363 - 369
High-throughput single-cell transcriptomics offers an unbiased approach for understanding the extent, basis and function of gene expression variation between... 
IMMUNE | VARIABILITY | DETERMINES | ACTIVATION | TRANSCRIPTOME | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | STOCHASTICITY | PRINCIPLES | I INTERFERON | Microfluidic Analytical Techniques | Antigens, Viral - pharmacology | Paracrine Communication | Gene Expression Regulation - immunology | Dendritic Cells - immunology | RNA, Messenger - genetics | Cell Communication | Gene Expression Profiling | Animals | Base Sequence | Interferon-beta - genetics | Dendritic Cells - drug effects | RNA, Messenger - chemistry | Mice | Single-Cell Analysis | Immunity - genetics | Principal Component Analysis | Physiological aspects | Unicellular organisms | Cell research | Research | RNA | Dendritic cells | Principal components analysis | Cytokines | Gene expression | Ribonucleic acid--RNA | Genomics | Immune system
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3. Full Text Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
by Shalek, Alex K and Satija, Rahul and Adiconis, Xian and Gertner, Rona S and Gaublomme, Jellert T and Raychowdhury, Raktima and Schwartz, Schraga and Yosef, Nir and Malboeuf, Christine and Lu, Diana and Trombetta, John J and Gennert, Dave and Gnirke, Andreas and Goren, Alon and Hacohen, Nir and Levin, Joshua Z and Park, Hongkun and Regev, Aviv
Nature, ISSN 0028-0836, 2013, Volume 498, Issue 7453, pp. 236 - 240
Recent molecular studies have shown that, even when derived from a seemingly homogenous population, individual cells can exhibit substantial differences in... 
LEVEL | MESSENGER-RNA-SEQ | PATHWAY | MULTIDISCIPLINARY SCIENCES | STAT2 Transcription Factor | Reproducibility of Results | Bone Marrow Cells - cytology | Gene Expression Regulation - immunology | Dendritic Cells - immunology | RNA, Messenger - genetics | RNA, Messenger - analysis | In Situ Hybridization, Fluorescence | Viruses - immunology | Gene Expression Profiling | Transcriptome - genetics | Interferons - immunology | Lipopolysaccharides - immunology | Mice, Knockout | Animals | Sequence Analysis, RNA | Interferon Regulatory Factor-7 | Bone Marrow Cells - immunology | RNA Splicing - immunology | Dendritic Cells - cytology | Mice | Single-Cell Analysis | Dendritic Cells - metabolism | Protein Isoforms - genetics | RNA sequencing | Phenotype | Cellular control mechanisms | Research | Gene expression | Observations | Testing | Proteins | Noise | Cell cycle
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4. Full Text Dynamic regulatory network controlling T H 17 cell differentiation
by Yosef, Nir and Shalek, Alex K and Gaublomme, Jellert T and Jin, Hulin and Lee, Youjin and Awasthi, Amit and Wu, Chuan and Karwacz, Katarzyna and Xiao, Sheng and Jorgolli, Marsela and Gennert, David and Satija, Rahul and Shakya, Arvind and Lu, Diana Y and Trombetta, John J and Pillai, Meenu R and Ratcliffe, Peter J and Coleman, Mathew L and Bix, Mark and Tantin, Dean and Park, Hongkun and Kuchroo, Vijay K and Regev, Aviv
Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, pp. 461 - 468
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5. Full Text Nuclei multiplexing with barcoded antibodies for single-nucleus genomics
by Gaublomme, JT and Li, B and McCabe, C and Knecht, A and Yang, YM and Drokhlyansky, E and Van Wittenberghe, N and Waldman, J and Dionne, D and Nguyen, L and De Jager, PL and Yeung, B and Zhao, XF and Habib, N and Rozenblatt-Rosen, O and Regev, A
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 2907 - 8
Single-nucleus RNA-seq (snRNA-seq) enables the interrogation of cellular states in complex tissues that are challenging to dissociate or are frozen, and opens... 
FRAMEWORK | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | DISCOVERY | Multiplexing | Medical research | Brain | Immunoglobulins | Computational neuroscience | Organs | Clinical trials | Antibodies | Genetic diversity | Perturbation | Gene expression | snRNA | Screens | Interrogation | Computer applications | Genetics | Nuclei (cytology) | Software | Atlases
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6. Full Text Somatic Mutation As a Mechanism of Wnt/β-Catenin Pathway Activation in CLL
by Wang, Lili and Shalek, Alex K and Gaublomme, Jellert and Lawrence, Michael and Stevenson, Kristen E and Neuberg, Donna S and Hacohen, Nir and Getz, Gad and Brown, Jennifer R and Park, Hongkun and Wu, Catherine J
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 559 - 559
Abstract Abstract 559 One goal of cancer genome sequencing is to identify key genes and pathways that drive tumor pathogenesis. While many studies identify... 
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7. Full Text Probing enzymatic activity inside living cells using a nanowire-cell "sandwich" assay
by Na, Yu-Ran and Kim, So Yeon and Gaublomme, Jellert T and Shalek, Alex K and Jorgolli, Marsela and Park, Hongkun and Yang, Eun Gyeong
Nano Letters, ISSN 1530-6984, 01/2013, Volume 13, Issue 1, pp. 153 - 158
Developing a detailed understanding of enzyme function in the context of an intracellular signal transduction pathway requires minimally invasive methods for... 
sandwich assembly | Silicon nanowire | enzyme activity | live cell assay | CASPASE ACTIVITIES | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | SILICON NANOWIRES | CHEMISTRY, PHYSICAL | RESONANCE ENERGY-TRANSFER | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY | PROTEIN-KINASES | ACTIVITY-BASED PROBES | BIOSENSORS | SUBSTRATE | FLUORESCENT-PROBES | DIFFERENTIATION | HeLa Cells | Nanowires | Humans | Mass Spectrometry | Enzymes - metabolism | Microscopy, Fluorescence | Enzymes | Cellular | Enzyme activity | Fluorescence | Kinases | Assaying | Arrays | Viability
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8. Full Text Nanowire-Mediated Delivery Enables Functional Interrogation of Primary Immune Cells: Application to the Analysis of Chronic Lymphocytic Leukemia
by Shalek, Alex K and Gaublomme, Jellert T and Wang, Lili and Yosef, Nir and Chevrier, Nicolas and Andersen, Mette S and Robinson, Jacob T and Pochet, Nathalie and Neuberg, Donna and Gertner, Rona S and Amit, Ido and Brown, Jennifer R and Hacohen, Nir and Regev, Aviv and Wu, Catherine J and Park, Hongkun
Nano Letters, ISSN 1530-6984, 12/2012, Volume 12, Issue 12, pp. 6498 - 6504
A circuit level understanding of immune cells and hematological cancers has been severely impeded by a lack of techniques that enable intracellular... 
delivery | immune cells | chronic lymphocytic leukemia | Nanowires | perturbation | GENE-EXPRESSION SIGNATURE | APOPTOSIS | PHYSICS, CONDENSED MATTER | CLL | PHYSICS, APPLIED | TGF-BETA | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | EMBRYONIC STEM | BIOMOLECULES | TOXICITY | CHEMISTRY, MULTIDISCIPLINARY | RNA, Small Interfering - genetics | Humans | Lymphoid Enhancer-Binding Factor 1 - genetics | Cells, Cultured | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Nanowires - chemistry | Animals | RNA Interference | Silicon - toxicity | Nanowires - toxicity | Mice | RNA, Small Interfering - administration & dosage | Silicon - chemistry | B-Lymphocytes - metabolism | Index Medicus | Therapy | Heterogeneity | Toxicity | Genes | Gene expression | Signatures | Patients | Leukemias | Letter
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9. Full Text Sensitivity to Wnt Pathway Inhibition in CLL Is Associated with Specific Gene Expression Signatures
by Wang, Lili and Shalek, Alex K and Gaublomme, Jellert and Yosef, Nir and Brown, Jennifer R and Neuberg, Donna and Hacohen, Nir and Park, Hongkun and Wu, Catherine J
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 801 - 801
Abstract Abstract 801 We have recently found that the Wnt/b-catenin signaling pathway plays a key role in chronic lymphocytic leukemia (CLL). We were, however,... 
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10. Full Text Identification and characterization of latency-associated peptide-expressing γδT cells
by Rezende, Rafael M and Da Cunha, Andre P and Kuhn, Chantal and Rubino, Stephen and M'Hamdi, Hanane and Gabriely, Galina and Vandeventer, Tyler and Liu, Shirong and Cialic, Ron and Pinheiro-Rosa, Natalia and Oliveira, Rafael P and Gaublomme, Jellert T and Obholzer, Nikolaus and Kozubek, James and Pochet, Nathalie and Faria, Ana M.C and Weiner, Howard L
Nature Communications, ISSN 2041-1723, 12/2015, Volume 6, Issue 1, p. 8726
γδ T cells are a subset of lymphocytes specialized in protecting the host against pathogens and tumours. Here we describe a subset of regulatory γδ T cells... 
Forkhead Transcription Factors - immunology | T-Lymphocyte Subsets - immunology | Humans | Activating Transcription Factor 3 - immunology | T-Lymphocytes, Regulatory - immunology | Transforming Growth Factor beta1 - immunology | Flow Cytometry | Intestinal Mucosa - immunology | Leukocytes, Mononuclear - immunology | Adult | Receptors, Antigen, T-Cell - immunology | Animals, Congenic | Colitis - immunology | Cytokines - genetics | Real-Time Polymerase Chain Reaction | Activating Transcription Factor 3 - genetics | Cytokines - immunology | Disease Models, Animal | Interferon-gamma | Receptors, Antigen, T-Cell, gamma-delta - immunology | Transforming Growth Factor beta1 - genetics | Forkhead Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Animals | Antigen-Presenting Cells | Mice | Peyer's Patches - immunology | In Vitro Techniques
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11. Full Text Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL
by Wang, Lili and Shalek, Alex K and Lawrence, Mike and Ding, Ruihua and Gaublomme, Jellert T and Pochet, Nathalie and Stojanov, Petar and Sougnez, Carrie and Shukla, Sachet A and Stevenson, Kristen E and Zhang, Wandi and Wong, Jessica and Sievers, Quinlan L and MacDonald, Bryan T and Vartanov, Alexander R and Goldstein, Natalie R and Neuberg, Donna and He, Xi and Lander, Eric and Hacohen, Nir and Regev, Aviv and Getz, Gad and Brown, Jennifer R and Park, Hongkun and Wu, Catherine J
Blood, ISSN 0006-4971, 08/2014, Volume 124, Issue 7, pp. 1089 - 1098
One major goal of cancer genome sequencing is to identify key genes and pathways that drive tumor pathogenesis. Although many studies have identified candidate... 
WNT SIGNALING PATHWAY | CELLS | IMPACT | INHIBITION | GENE | DYSREGULATION | CHRONIC LYMPHOCYTIC-LEUKEMIA | HEMATOLOGY | CANCER | ASSOCIATION | GENOME | Oligonucleotide Array Sequence Analysis | Humans | Cells, Cultured | Cell Survival - genetics | Gene Expression Profiling | Signal Transduction - genetics | Gene Expression Regulation, Leukemic | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Reverse Transcriptase Polymerase Chain Reaction | beta Catenin - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | RNA Interference | Wnt Signaling Pathway - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | HEK293 Cells | Cell Line, Tumor | Adult | Mutation | Lymphoid Neoplasia
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12. Full Text Probing Enzymatic Activity inside Living Cells Using a Nanowire–Cell “Sandwich” Assay
by Na, Yu-Ran and Kim, So Yeon and Gaublomme, Jellert T and Shalek, Alex K and Jorgolli, Marsela and Park, Hongkun and Yang, Eun Gyeong
Nano Letters, ISSN 1530-6984, 01/2013, Volume 13, Issue 1, pp. 153 - 158
Developing a detailed understanding of enzyme function in the context of an intracellular signal transduction pathway requires minimally invasive methods for... 
Silicon nanowire | sandwich assembly | enzyme activity | live cell assay
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13. Full Text Dynamic regulatory network controlling [T.sub.H]17 cell differentiation
by Yosef, Nir and Shalek, Alex K and Gaublomme, Jellert T and Jin, Hulin and Lee, Youjin and Awasthi, Amit and Wu, Chuan and Karwacz, Katarzyna and Xiao, Sheng and Jorgolli, Marsela and Gennert, David and Satija, Rahul and Shakya, Arvind and Lu, Diana Y and Trombetta, John J and Pillai, Meenu R and Ratcliffe, Peter J and Coleman, Mathew L and Bix, Mark and Tantin, Dean and Park, Hongkun and Kuchroo, Vijay K and Regev, Aviv
Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, p. 461
Control | Physiological aspects | Genetic aspects | Research | Cell differentiation | T cells | Genetic regulation
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14. Full Text Dynamic regulatory network controlling T^sub H^17 cell differentiation
by Nir Yosef and Alex K Shalek and Jellert T Gaublomme and Hulin Jin and Youjin Lee and Amit Awasthi and Chuan Wu and Katarzyna Karwacz and Sheng Xiao and Marsela Jorgolli and David Gennert and Rahul Satija and Arvind Shakya and Diana Y Lu and John J Trombetta and Meenu R Pillai and Peter J Ratcliffe and Mathew L Coleman and Mark Bix and Dean Tantin and Hongkun Park and Vijay K Kuchroo and Aviv Regev
Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, p. 461
  [...]many of the key regulators and interactions that drive the development of TH17 cells remain unknown5. Because different regulators act at different... 
Proteins | Cytokines | Lymphocytes | Genomics | Gene expression
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15. Full Text Dynamic regulatory network controlling TH17 cell differentiation
by Yosef, Nir and Shalek, Alex K and Gaublomme, Jellert T and Jin, Hulin and Lee, Youjin and Awasthi, Amit and Wu, Chuan and Karwacz, Katarzyna and Xiao, Sheng and Jorgolli, Marsela and Gennert, David and Satija, Rahul and Shakya, Arvind and Lu, Diana Y and Trombetta, John J and Pillai, Meenu R and Ratcliffe, Peter J and Coleman, Mathew L and Bix, Mark and Tantin, Dean and Park, Hongkun and Kuchroo, Vijay K and Regev, Aviv
Nature, ISSN 0028-0836, 04/2013, Volume 496, Issue 7446, pp. 461 - 468
Despite their importance, the molecular circuits that control the differentiation of naive T cells remain largely unknown. Recent studies that reconstructed... 
Genome - genetics | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | fas Receptor - metabolism | Gene Knockdown Techniques | Cell Differentiation - genetics | Th17 Cells - metabolism | Time Factors | Forkhead Transcription Factors - metabolism | Th17 Cells - cytology | Silicon | Reproducibility of Results | Gene Regulatory Networks - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Nuclear Proteins - metabolism | DNA - metabolism | DNA - genetics | Transcription Factors - metabolism | Interleukin-2 - genetics | Animals | Th17 Cells - immunology | Trans-Activators - metabolism | Mice | Nanowires | Transcription, Genetic - genetics | Interferon-gamma - biosynthesis
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16. Full Text Identification and characterization of latency-associated peptide-expressing [gamma][delta] T cells
by Rafael M Rezende and Andre P Da Cunha and Chantal Kuhn and Stephen Rubino and Hanane M'hamdi and Galina Gabriely and Tyler Vandeventer and Shirong Liu and Ron Cialic and Natalia Pinheiro-rosa and Rafael P Oliveira and Jellert T Gaublomme and Nikolaus Obholzer and James Kozubek and Nathalie Pochet and Ana M C Faria and Howard L Weiner
Nature Communications, 12/2015, Volume 6, p. 8726
γδ T cells are a subset of lymphocytes specialized in protecting the host against pathogens and tumours. Here we describe a subset of regulatory γδ T cells... 
CD27 antigen | Peyer's patches | Antigen presentation | Antigens | Phenotypes | Peptides | Immunoregulation | Lamina propria | Lymphocytes T | Small intestine | Thymus | Latency | CD4 antigen | Lymphocytes | Antigen-presenting cells | γ-Interferon | Foxp3 protein | CCR9 protein | Cell migration | Tumors
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17. USE OF NANOWIRES FOR DELIVERING BIOLOGICAL EFFECTORS INTO IMMUNE CELLS
by SHALEK ALEXANDER K and PARK HONGKUN and GAUBLOMME JELLERT T
07/2015
The present invention generally relates to nanowires and, in some aspects, to methods of using nanowire arrays to identify a therapeutic target for treating a... 
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS | SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES | ENZYMOLOGY | MICROBIOLOGY | MEASURING | MUTATION OR GENETIC ENGINEERING | SPIRITS | COMPOSITIONS THEREOF | PROCESSES OF PREPARING SUCH COMPOSITIONS | BIOCHEMISTRY | CULTURE MEDIA | CHEMISTRY | VINEGAR | NANOTECHNOLOGY | WINE | TRANSPORTING | MANUFACTURE OR TREATMENT OF NANOSTRUCTURES | MICROORGANISMS OR ENZYMES | COMPOSITIONS OR TEST PAPERS THEREFOR | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES | MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES | BEER | PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS | TESTING | METALLURGY | CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES | PHYSICS | PERFORMING OPERATIONS
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18. USE OF NANOWIRES FOR DELIVERING BIOLOGICAL EFFECTORS INTO IMMUNE CELLS
by SHALEK, ALEXANDER, K and GAUBLOMME, JELLERT, T and PARK, HONGKUN
02/2014
The present invention generally relates to nanowires and, in some aspects, to methods of using nanowire arrays to identify a therapeutic target for treating a... 
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS | SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES | ENZYMOLOGY | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY | MICROBIOLOGY | MEASURING | MUTATION OR GENETIC ENGINEERING | SPIRITS | COMPOSITIONS THEREOF | PROCESSES OF PREPARING SUCH COMPOSITIONS | BIOCHEMISTRY | CULTURE MEDIA | CHEMISTRY | VINEGAR | NANOTECHNOLOGY | WINE | TRANSPORTING | MANUFACTURE OR TREATMENT OF NANOSTRUCTURES | MICROORGANISMS OR ENZYMES | COMPOSITIONS OR TEST PAPERS THEREFOR | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES | MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES | PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL | BEER | PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS | TESTING | THEIR RELEVANT APPARATUS | METALLURGY | CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES | PHYSICS | PERFORMING OPERATIONS
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19. Full Text Geometry-dependent functional changes in iPSC-derived cardiomyocytes probed by functional imaging and RNA sequencing
by Werley, Christopher A and Chien, Miao-Ping and Gaublomme, Jellert and Shekhar, Karthik and Butty, Vincent and Yi, B. Alexander and Kralj, Joel M and Bloxham, William and Boyer, Laurie A and Regev, Aviv and Cohen, Adam E
PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, p. e0172671
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising platform for cardiac studies in vitro, and possibly for tissue repair in... 
ACTION-POTENTIALS | MYOCARDIUM | VOLTAGE | STIMULATION | MULTIDISCIPLINARY SCIENCES | CALCIUM | CARDIAC-CELLS | DIFFERENTIATION | PLURIPOTENT STEM-CELL | MATURATION | CULTURE | Induced Pluripotent Stem Cells - physiology | Calcium - metabolism | Gene Expression - genetics | Humans | Cells, Cultured | Electrophysiological Phenomena - physiology | Action Potentials - physiology | Sequence Analysis, RNA - methods | Cell Differentiation - genetics | Myocytes, Cardiac - physiology | Myocytes, Cardiac - metabolism | Transcription, Genetic - genetics | Induced Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - metabolism | RNA sequencing | Analysis | Stem cells | Heart cells | Models | Research | Health aspects | Heart | Bioengineering | Cell culture | Transcription | Electric contacts | Calcium | Genes | Electrophysiology | Action potential | Biology | Gene sequencing | Calcium signalling | Biomedical materials | Rodents | Extracellular matrix | Islands | Heart diseases | Medical research | Maturation | Calcium channels (voltage-gated) | Cardiomyocytes | Metabolism | Gene expression | Ribonucleic acid--RNA | Mathematical morphology | Embryos | Chemistry | Morphology | Proteomics | Set theory | Pluripotency | RNA | Ribonucleic acid
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