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2018, Methods in Molecular Biology, ISBN 9781493977000, Volume 1749
eBook
Nature Protocols, ISSN 1754-2189, 2014, Volume 9, Issue 8, pp. 1931 - 1943
The mechanism by which cells control directional persistence during migration is a major question. However, the common index measuring directional persistence,... 
MOTION | TRACKING | BIOCHEMICAL RESEARCH METHODS | Cell Migration Assays - methods | Software | Cell Movement | Physiological aspects | Research | Cells | Cell migration
Journal Article
Physiological Reviews, ISSN 0031-9333, 01/2018, Volume 98, Issue 1, p. 215
The Arp2/3 complex is an evolutionary conserved molecular machine that generates branched actin networks. When activated, the Arp2/3 complex contributes the... 
Proteins | Molecules | Membranes | Evolutionary conservation | Membrane trafficking | Cells | Cell migration | Cancer | Structure-function relationships
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1749, pp. 11 - 19
Cell migration is suppressed by confluence in a process called contact inhibition. Relieving contact inhibition upon scratching is one of the simplest ways to... 
Scratch | Proliferation | Insert | Videomicroscopy | Migration | Cell Line, Tumor | Cell Migration Assays - methods | Wound Healing - physiology | Humans | Cell Movement - physiology | Life Sciences | Molecular biology | Cellular Biology | Quantitative Methods | Biochemistry, Molecular Biology | Cancer
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1749, pp. 1 - 9
Cell migration is essential to many biological processes such as embryonic development, immune surveillance and wound healing. Random cell migration refers to... 
Directionality | Persistence | Speed | Autocorrelation | Cell tracking | MSD | Cell Line, Tumor | Cell Migration Assays - methods | Wound Healing - physiology | Humans | Cell Movement - physiology | Extracellular Matrix Proteins - metabolism | Life Sciences | Molecular biology | Cellular Biology | Quantitative Methods | Biochemistry, Molecular Biology | Cancer
Journal Article
Cytoskeleton, ISSN 1949-3584, 07/2015, Volume 72, Issue 7, pp. 362 - 371
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 288 - 288
Journal Article
Cytoskeleton, ISSN 1949-3584, 07/2015, Volume 72, Issue 7, pp. 362 - 371
Journal Article
Cell research, ISSN 1001-0602, 04/2019, Volume 29, Issue 6, pp. 432 - 445
The actin cytoskeleton generates and senses forces. Here we report that branched actin networks from the cell cortex depend on ARPC1B-containing Arp2/3... 
Epithelial cells | Cortex | Rac1 protein | Breast cancer | Rigidity | Metastases | Actin | Dependence | Cell cycle | Cytoskeleton | Diagnostic systems | Mechanotransduction | Mammary gland | Growth factors | Cell migration | Tumors | G1 phase | Life Sciences | Cellular Biology | Subcellular Processes
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 08/2019, Volume 294, Issue 35, pp. 12992 - 13005
Although Merlin's function as a tumor suppressor and regulator of mitogenic signaling networks such as the Ras/rac, Akt, and Hippo pathways is well-documented,... 
ACTIVATION | ERM PROTEINS | cell proliferation | BIOCHEMISTRY & MOLECULAR BIOLOGY | tubulin | TUMOR-SUPPRESSOR GENE | isoforms | ezrin | mitosis | CELL CORTEX | PATHWAY | PRODUCT | MISSENSE MUTATION | neurofibromatosis type 2 | cancer biology | NF2 | phosphorylation | NEUROFIBROMATOSIS TYPE-2 | TUMORIGENESIS | tumor suppressor gene | Aurora A | Merlin | Life Sciences | Cellular Biology | Subcellular Processes
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 2013, Volume 23, Issue 11, pp. 522 - 528
Highlights • Localised actin patches on endosomes define discrete domains to facilitate protein sorting. • Formation of branched actin on endosomes requires... 
Pathology | Fam21 | endosome | actin | WASH complex | retromer | sorting | Actin | Endosome | Retromer | Sorting | RECRUITMENT | WASP FAMILY | COMPLEX | TRAFFICKING | RETRIEVAL | CELL BIOLOGY | TRANSPORT | GENE | ARP2/3 ACTIVATOR | MUTATIONS | Animals | Vesicular Transport Proteins - metabolism | Humans | Actins - metabolism | Polymerization | Microfilament Proteins - metabolism | Endosomes - metabolism | Protein Transport | Muscle proteins | Membrane proteins
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2014, Volume 33, Issue 23, pp. 2745 - 2764
Journal Article