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Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 02/2016, Volume 75, Issue 2, pp. 422 - 429
ObjectiveTo investigate the effects of BET bromodomain protein inhibition on inflammatory activation and functional properties of rheumatoid arthritis synovial... 
EPIGENETICS | ACTIVATION | SECUKINUMAB | CHROMATIN | DOUBLE-BLIND | ANTI-INTERLEUKIN-17A MONOCLONAL-ANTIBODY | RHEUMATOLOGY | BET PROTEIN | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Gene Expression - drug effects | Humans | Lipopolysaccharides - metabolism | Arthritis, Rheumatoid - enzymology | Matrix Metalloproteinase 3 - metabolism | Nuclear Proteins - metabolism | RNA, Messenger - metabolism | Synovial Membrane - metabolism | Heterocyclic Compounds, 4 or More Rings - pharmacology | Osteoarthritis - genetics | Osteoarthritis - enzymology | Transcription Factors - metabolism | Arthritis, Rheumatoid - genetics | Interleukin-1beta - metabolism | Interleukin-8 - metabolism | Toll-Like Receptors - metabolism | Matrix Metalloproteinase 1 - metabolism | Interleukin-6 - metabolism | Protein-Serine-Threonine Kinases - metabolism | RNA-Binding Proteins - metabolism | Fibroblasts - metabolism | Epigenetic inheritance | Care and treatment | Interleukins | Tumor necrosis factor | Rheumatoid arthritis | Dosage and administration | Research | Enzymes | Immunoglobulins | Statistical analysis | Disease | Cytokines | Laboratories | Gene expression | Variance analysis | Bone surgery | Studies | Proteins | Pathology | Rodents | DNA methylation | Epigenetics | Fibroblasts | Tumor necrosis factor-TNF | Chemokines | Deoxyribonucleic acid--DNA
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 10/2011, Volume 70, Issue 10, pp. 1866 - 1873
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 10/2014, Volume 73, Issue 10, pp. 1898 - 1904
Journal Article
Nature Communications, ISSN 2041-1723, 03/2017, Volume 8, Issue 1, p. 14852
A number of human diseases, such as arthritis and atherosclerosis, include characteristic pathology in specific anatomical locations. Here we show... 
SITE | LONG NONCODING RNA | DNA METHYLATION | CHROMATIN | EROSIVE OSTEOARTHRITIS | PALMOPLANTAR FIBROBLASTS | HOMEOTIC GENE | MULTIDISCIPLINARY SCIENCES | HOX GENES | EXPRESSION | HISTONE
Journal Article
Journal Article
BioDrugs, ISSN 1173-8804, 06/2012, Volume 26, Issue 3, pp. 131 - 141
Rheumatoid arthritis (RA) is a systemic, inflammatory, autoimmune disorder with progressive articular damage that may result in lifelong disability. Although... 
Journal Article
European Heart Journal, ISSN 0195-668X, 12/2014, Volume 35, Issue 45, pp. 3203 - 3211
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 10/2014, Volume 73, Issue 10, pp. 1880 - 1887
Journal Article