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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2015, Volume 112, Issue 8, pp. 2473 - 2478
The malignant progression of pancreatic ductal adenocarcinoma (PDAC) is accompanied by a profound desmoplasia, which forces proliferating tumor cells to... 
PROTEIN | MULTIDISCIPLINARY SCIENCES | GLYCOLYSIS | pancreatic cancer | PATHWAY | PROSTATE-CANCER | LIPID RAFTS | cholesterol | S-PHASE | metabolism | gemcitabine | CELL-CYCLE | KRAS | ACCUMULATION | SIMVASTATIN | LDLR | Adenocarcinoma - pathology | Epithelial Cells - metabolism | Gene Silencing - drug effects | Pancreatic Neoplasms - metabolism | Prognosis | Epithelial Cells - drug effects | Humans | Deoxycytidine - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Pancreatic Neoplasms - drug therapy | Deoxycytidine - therapeutic use | Adenocarcinoma - metabolism | Lipoproteins - metabolism | Clone Cells | Gene Expression Regulation, Neoplastic - drug effects | Receptors, LDL - genetics | Pancreatic Neoplasms - pathology | Adenocarcinoma - enzymology | Pancreatic Neoplasms - enzymology | Receptors, LDL - metabolism | Epithelial Cells - pathology | Up-Regulation - genetics | Cholesterol - metabolism | Adenocarcinoma - drug therapy | Up-Regulation - drug effects | Metabolic Networks and Pathways - genetics | Phenotype | Animals | MAP Kinase Signaling System - drug effects | Cell Compartmentation - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Metabolic Networks and Pathways - drug effects | Deoxycytidine - analogs & derivatives | Pancreatic cancer | Carcinoma, Ductal | Development and progression | Genetic aspects | Genetic transcription | Cholesterol metabolism | Health aspects | Biological Sciences
Journal Article
Neuron, ISSN 0896-6273, 2007, Volume 56, Issue 5, pp. 807 - 822
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1978 - 10
Journal Article
Journal Article
Frontiers in oncology, ISSN 2234-943X, 2019, Volume 9, p. 475
Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease, therefore stratification of patients is essential to predict their responses to therapies... 
Usage | Pancreatic cancer | Genetic aspects | Endoscopy | Diagnosis | Genetic transcription | Research | Medicine, Experimental | Medical research | Care and treatment | Analysis | pancreatic cancer | JQ1 | c-MYC | organoids | NHWD-870
Journal Article
Oncotarget, ISSN 1949-2553, 07/2018, Volume 9, Issue 56, pp. 30837 - 30846
In this study, our aim is to assess the role played by autophagy and its inhibition in the different PDAC cellular compartments, and its involvement in... 
Gemcitabine | Autophagy | Chloroquine | Pancreas cancer
Journal Article
Molecular and Cellular Proteomics, ISSN 1535-9476, 12/2014, Volume 13, Issue 12, pp. 3585 - 3601
Journal Article