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Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, p. 34656
The NF kappa B and MAPK signaling pathways are critical components of innate immunity that orchestrate appropriate immune responses to control and eradicate... 
GINGIPAINS | NECROSIS | EPITHELIAL-CELLS | PORPHYROMONAS-GINGIVALIS | MULTIDISCIPLINARY SCIENCES | LIPID RAFTS | ENDOTHELIAL-CELLS | AKT | ACTIVATED PROTEIN-KINASES | NF-KAPPA-B | RIP1 | Human Umbilical Vein Endothelial Cells | Porphyromonas gingivalis - enzymology | RNA, Small Interfering - genetics | Cell Adhesion Molecules - genetics | Porphyromonas gingivalis - pathogenicity | Adhesins, Bacterial - genetics | Humans | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - immunology | Cell Adhesion Molecules - immunology | Paracrine Communication - immunology | Proto-Oncogene Proteins c-akt - genetics | Host-Pathogen Interactions - immunology | Proteolysis | Mitogen-Activated Protein Kinase 1 - genetics | HEK293 Cells | Tumor Necrosis Factor-alpha - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - immunology | Cytokines - genetics | Cytokines - immunology | Porphyromonas gingivalis - genetics | Mitogen-Activated Protein Kinase 3 - immunology | Mitogen-Activated Protein Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Signal Transduction | MAP Kinase Kinase Kinases - genetics | Gene Expression Regulation | Immunity, Innate | MAP Kinase Kinase Kinases - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins c-akt - immunology | NF-kappa B - genetics | Cysteine Endopeptidases - genetics | HeLa Cells | Adhesins, Bacterial - immunology | Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors | Cysteine Endopeptidases - immunology | RNA, Small Interfering - metabolism
Journal Article
Lancet Respiratory Medicine, The, ISSN 2213-2600, 2017, Volume 5, Issue 5, pp. 412 - 425
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2014, Volume 34, Issue 3, pp. 552 - 564
OBJECTIVE—Interleukin 1 Receptor 1 (IL1R1) and its ligand, IL1β, are upregulated in cardiovascular disease, obesity, and infection. Previously, we reported a... 
Infection | Diet, high-fat | Megakaryocytes | Blood platelets | IL1R1 protein, human | THROMBOPOIESIS | CELLS | blood platelets | infection | megakaryocytes | HIGH-FAT DIET | CANAKINUMAB | ATHEROSCLEROSIS | IL1R1 protein | ARTERIES | CYTOKINE PRODUCTION | INHIBITION | high-fat | PERIPHERAL VASCULAR DISEASE | IL-1-BETA | diet | HEMATOLOGY | human | EXPRESSION | Inflammation - pathology | Transcription, Genetic - drug effects | Interleukin-1beta - pharmacology | Receptors, Interleukin-1 Type I - physiology | Humans | Platelet Activation - physiology | Platelet Adhesiveness - physiology | NF-kappa B - metabolism | Gene Expression Profiling | Obesity - blood | Obesity - genetics | Atherosclerosis - etiology | Bacteroidaceae Infections - blood | Thrombin - pharmacology | Protein Processing, Post-Translational - drug effects | Collagen - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Megakaryocytes - cytology | Proto-Oncogene Proteins c-akt - metabolism | Bacteroidaceae Infections - pathology | Disease Models, Animal | Receptors, Interleukin-1 Type I - deficiency | Porphyromonas gingivalis | Cell Line | Interleukin-1beta - physiology | Obesity - complications | Imidazoles - pharmacology | Inflammation - etiology | Mice, Knockout | Platelet Adhesiveness - drug effects | Transcription, Genetic - physiology | Animals | MAP Kinase Signaling System - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Receptors, Interleukin-1 Type I - genetics | Inflammation - genetics | Mice | Platelet Activation - drug effects | Pyridines - pharmacology | Dietary Fats - toxicity
Journal Article
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