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Computers in Biology and Medicine, ISSN 0010-4825, 04/2019, Volume 107, pp. 161 - 171
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 01/2018, Volume 119, Issue 1, pp. 555 - 565
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2018, Volume 119, Issue 11, pp. 8851 - 8861
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 11/2018, Volume 119, Issue 11, pp. 8851 - 8861
Gene polymorphism among humans is one of the factors governing individual’s susceptibility and resistance to various diseases including cancer. DNA repair... 
Glu87Gln | cancer | polymorphism | in silico modeling | molecular dynamics | Apex 1 | Prevention | Care and treatment | Analysis | Genes | Molecular dynamics | Genetic research | Head and neck cancer | Development and progression | Disease susceptibility | Genetic aspects | Cancer
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 09/2018, Volume 119, Issue 9, pp. 7585 - 7598
Journal Article
Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 09/2017, Volume 8, pp. 132 - 143
In the past few years, therapeutic microRNA (miRNA) and small interfering RNA (siRNA) are some of the most important biopharmaceuticals that are in commercial... 
drug development | miRNA | siRNA | NONHUMAN-PRIMATES | TARGETED NANOPARTICLES | MEDICINE, RESEARCH & EXPERIMENTAL | DOUBLE-STRANDED-RNA | CAENORHABDITIS-ELEGANS | DRUG DISCOVERY | IN-VIVO | INTERFERENCE | MICRORNA THERAPEUTICS | ANTISENSE OLIGONUCLEOTIDES | HEPATITIS-C
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 01/2018, Volume 119, Issue 1, pp. 555 - 565
Mutations in the IDUA gene lead to mild to severe forms of disease known as Mucopolysachharidosis type I caused due to the deficiency of alpha‐L‐iduronidase... 
nsSNPs | IN SILICO | IDUA | MOLECULAR DYNAMICS | DELETERIOUS
Journal Article
Current Drug Targets, ISSN 1389-4501, 12/2013, Volume 14, Issue 14, pp. 1707 - 1713
Osteoporosis, a multifaceted bone disorder, is considered as a serious health problem throughout the world and the magnitude of diseased patients is increasing... 
Journal Article
Biological research, 07/2015, Volume 48, p. 35
The current state of the art in medical genetics is to identify and classify the functional (deleterious) or non-functional (neutral) single amino acid... 
Sequence Analysis, Protein | Phenotype | Humans | Computational Biology | Amino Acid Substitution - genetics | Genotype | Blood Coagulation Factors - genetics | Polymorphism, Single Nucleotide | Databases, Factual
Journal Article
Bioprocess and Biosystems Engineering, ISSN 1615-7591, 09/2015, Volume 38, Issue 9, p. 1655
[beta]-Galactosidase from Lactobacillus plantarum HF571129 was immobilized on zinc oxide nanoparticles (ZnO NPs) using adsorption and cross-linking technique.... 
Nanoparticles | Hydrolysis | Enzymes | Crosslinked polymers | Lactose | Adsorption | Zinc oxide | Activation energy | Bioengineering | Zinc oxides | Bacteria
Journal Article
Life Sciences, ISSN 0024-3205, 12/2016, Volume 166, p. 108
The pace of anti-diabetic drug discovery is very slow in spite of increasing rate of prevalence of Type 2 Diabetes which remains a major public health concern.... 
Drugs | Medical research | Peptidase | Identification methods | Diabetes mellitus | Clinical trials | Markets | Pharmacology | Lead compounds | Knowledge | Proteins | Inhibitors | Enzyme inhibitors | Computation | Computer applications | Lead | Life sciences | Diabetes | Drug discovery | Public health | Combinatorial analysis
Journal Article
Interdisciplinary Sciences: Computational Life Sciences, ISSN 1913-2751, 06/2018, Volume 10, Issue 2, p. 261
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s12539-016-0187-2 Despite... 
Antioxidants | Analysis | Force and energy
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0174953 - e0174953
Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. Over the past years, several... 
PROTEIN STABILITY | GENE | MULTIDISCIPLINARY SCIENCES | SEQUENCE | ARGININE | BETA-CELL | MOLECULAR-DYNAMICS SIMULATIONS | TRANSCRIPTION FACTOR | SALT BRIDGES | WEB SERVER | PREDICTION | Amino Acid Sequence | Protein Binding - genetics | Mutagenesis, Site-Directed | Hepatocyte Nuclear Factor 1-alpha - chemistry | Hepatocyte Nuclear Factor 1-alpha - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Recombinant Proteins - chemistry | DNA - metabolism | Mutation, Missense | Recombinant Proteins - biosynthesis | Hepatocyte Nuclear Factor 1-alpha - metabolism | Static Electricity | Protein Domains - genetics | Recombinant Proteins - isolation & purification | DNA - chemistry | Hydrogen Bonding | Hydrophobic and Hydrophilic Interactions | Molecular Docking Simulation | Diabetes Mellitus, Type 2 - pathology | Protein Stability | Binding Sites | Principal Component Analysis | Physiological aspects | Transcription factors | Research | Gene mutations | DNA-ligand interactions | Biological properties | Residues | Cysteine | Salts | Genes | Molecular dynamics | Variations | HNF1a protein | Hydrogen bonding | Molecular docking | Homeobox | Proteins | Conserved sequence | Missense mutation | Arginine | Hydrogen bonds | Dimensional analysis | Hepatocyte nuclear factor 1 | Deoxyribonucleic acid--DNA | Pathogens | Nucleotide sequence | Computer simulation | Secretion | Diabetes mellitus | Stability analysis | Electrostatic properties | Insulin | Pathogenicity | Simulation | Computer applications | Affinity | Diabetes | Mutation | Protein interaction | Protein structure | Binding sites | Structure-function relationships | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, p. e34573
Journal Article
生物学前沿:英文版, ISSN 1674-7984, 2015, Volume 10, Issue 4, pp. 377 - 385
Journal Article