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PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, p. e111266
We evaluated micro (mi) RNA-mediated regulation of BAFF expression in fibroblasts using two concomitant models: (i) synovial fibroblasts (FLS) isolated from... 
B-LYMPHOCYTE STIMULATOR | EPITHELIAL-CELLS | SYNOVIAL FIBROBLASTS | CELL-ACTIVATING FACTOR | AUTOIMMUNE-DISEASES | MULTIDISCIPLINARY SCIENCES | SYNOVIOCYTES | MICRORNAS | RELEASE | EXPRESSION | TNF FAMILY | Cell Survival - drug effects | B-Cell Activating Factor - biosynthesis | B-Lymphocytes - cytology | Poly I-C - pharmacology | Humans | Middle Aged | Scleroderma, Systemic - genetics | Scleroderma, Systemic - pathology | 3' Untranslated Regions - genetics | Male | Scleroderma, Systemic - immunology | Down-Regulation - drug effects | Down-Regulation - genetics | Arthritis, Rheumatoid - pathology | B-Lymphocytes - drug effects | Arthritis, Rheumatoid - genetics | B-Cell Activating Factor - genetics | Base Sequence | Fibroblasts - drug effects | Female | MicroRNAs - genetics | Arthritis, Rheumatoid - immunology | Interferon-gamma - pharmacology | Fibroblasts - metabolism | Autoimmunity | Rheumatoid factor | Systemic lupus erythematosus | MicroRNA | Systemic scleroderma | Analysis | Scleroderma (Disease) | Hostages | Arthritis | B cells | Enzyme-linked immunosorbent assay | Antisense | Kinases | Proteins | Control | Transfection | Synthesis | Repressors | Fibroblasts | Lupus | Cell survival | Cytokines | Dendritic cells | Secretion | MiRNA | Poly (I:C) | Gene expression | Ribonucleic acid--RNA | Patients | Lymphocytes B | BLyS protein | Rheumatoid arthritis | Systemic sclerosis | MicroRNAs | γ-Interferon | Skin | Autoimmune diseases | RNA | Ribonucleic acid
Journal Article
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 11/2017, Volume 69, Issue 11, pp. 2124 - 2135
Journal Article
Biochemistry and Cell Biology, ISSN 0829-8211, 12/2015, Volume 93, Issue 6, p. 626
  Within the past two decades, the fields of chromatin structure and function and transcription regulation research started to fuse and overlap, as evidence... 
Proteins | Chromatin | Epigenetics | DNA methylation | Biochemistry | Gene expression
Journal Article
Biochemistry and Cell Biology, ISSN 0829-8211, 12/2017, Volume 95, Issue 6, p. 593
This paper provides a brief introductory review of the most recent advances in our knowledge about the structural and functional aspects of two transcriptional... 
Silencers | Chromatin | Regulators | Transcription | Genes | Crosstalk | Gene expression | Substrates | Proteins | Methyl-CpG binding protein | MeCP2 protein | Rett syndrome | Mutation | Structure-function relationships
Journal Article
Nature, ISSN 0028-0836, 02/2005, Volume 433, Issue 7025, pp. 523 - 527
Toll-like receptor 2 (TLR2) is required for the recognition of numerous molecular components of bacteria, fungi and protozoa. The breadth of the ligand... 
TOLL-LIKE RECEPTOR-2 | IMMUNE-RESPONSE | PATTERN-RECOGNITION | LIPOTEICHOIC ACID | GENE | METABOLISM | MULTIDISCIPLINARY SCIENCES | FATTY-ACID | LIPOPOLYSACCHARIDE | IDENTIFICATION | LIPOPROTEINS | Peptidoglycan - metabolism | Toll-Like Receptor 2 | CD36 Antigens - genetics | Membrane Glycoproteins - metabolism | Staphylococcus aureus - physiology | Humans | Membrane Glycoproteins - chemistry | Peptidoglycan - chemistry | Zymosan - pharmacology | Mutagenesis - drug effects | Toll-Like Receptors | CD36 Antigens - metabolism | Gene Deletion | Receptors, Cell Surface - chemistry | Staphylococcal Infections - microbiology | Dimerization | Oligopeptides - chemistry | Staphylococcal Infections - metabolism | Cell Line | Oligopeptides - chemical synthesis | Glycerides - chemistry | Staphylococcal Infections - genetics | Signal Transduction | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Membrane Glycoproteins - agonists | Receptors, Cell Surface - agonists | Receptors, Cell Surface - metabolism | Glycerides - metabolism | Mutation - genetics | Immunologic Deficiency Syndromes - chemically induced | Ethylnitrosourea - pharmacology | Mice, Knockout | Staphylococcus aureus - chemistry | Homozygote | Glycerides - pharmacology | Phenotype | Animals | Aging - physiology | Receptors, Cell Surface - deficiency | Mice | Oligopeptides - pharmacology | Peptidoglycan - pharmacology | Lipopeptides | Tumor Necrosis Factor-alpha - biosynthesis | Membrane Glycoproteins - deficiency | Rodents | Immunology | Sensors
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2013, Volume 4, p. 70
MicroRNAs (miRNAs) are now recognized as essential regulators of gene expression in plants and animals. They potentially modulate the expression of multiple... 
MiR-17 ∼ 92 | Inflammation | MiRNA cluster | TLR | ASK1 | Rheumatoid arthritis | miRNA cluster | miR-17~92
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 2007, Volume 27, Issue 1, pp. 123 - 134
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2004, Volume 101, Issue 10, pp. 3516 - 3521
Several subsets of dendritic cells have been shown to produce type I IFN in response to viral infections, thereby assisting the natural killer cell-dependent... 
Biological Sciences | Phenotypes | Receptors | Double stranded RNA | Cytokines | Natural killer T cells | Alleles | Infections | Mice | Viral infections | Genotypes | PLASMACYTOID DENDRITIC CELLS | INTERFERON-ALPHA/BETA | NATURAL-KILLER-CELLS | DOUBLE-STRANDED-RNA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MURINE CYTOMEGALOVIRUS | NF-KAPPA-B | BACTERIAL CPG-DNA | VIRAL-INFECTION | ACTIVATION RECEPTOR | Toll-Like Receptor 3 | Membrane Glycoproteins - metabolism | DNA, Complementary - genetics | Immunity, Innate - genetics | Molecular Sequence Data | Toll-Like Receptor 9 | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - genetics | Mutation, Missense | DNA-Binding Proteins - metabolism | Toll-Like Receptors | Mice, Mutant Strains | Oligodeoxyribonucleotides - genetics | Killer Cells, Natural - immunology | Antigens, Differentiation - metabolism | Amino Acid Sequence | Immunity, Innate - drug effects | Signal Transduction | Mice, Inbred C57BL | Receptors, Immunologic - deficiency | Receptors, Cell Surface - metabolism | Myeloid Differentiation Factor 88 | DNA-Binding Proteins - genetics | Membrane Glycoproteins - genetics | Mice, Knockout | Sequence Homology, Amino Acid | Point Mutation | Adaptor Proteins, Signal Transducing | Phenotype | Animals | Receptors, Cell Surface - deficiency | Antigens, Differentiation - genetics | Mice, Inbred BALB C | Oligodeoxyribonucleotides - pharmacology | Receptors, Immunologic - genetics | Cytokines - biosynthesis | Membrane Glycoproteins - deficiency | Receptors, Immunologic - metabolism | Receptors, Cell Surface - genetics | Dendritic cells | Research
Journal Article