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Science, ISSN 0036-8075, 1/2010, Volume 327, Issue 5965, pp. 580 - 583
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2017, Volume 114, Issue 31, p. 8348
Glycolipid antigens recognized by aβ T-cell receptors (TCRs) drive the activation of invariant natural killer T (iNKT) cells, a specialized subset of innate T... 
Antigens | Carbohydrates | Biochemical analysis | Lipids | Mass spectroscopy | Lymphocytes T | Adipocytes | Mammals | T-cell receptor | CD1d antigen | Receptors | Microorganisms | Cow's milk | Diet | Glycolipids | Lymphocytes | Natural killer cells | Mass spectrometry | Milk
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 48, p. 14948
  Interleukin (IL)-6 blockade is an effective treatment for rheumatoid arthritis (RA), and synovial fibroblasts are a major IL-6 producer in the inflamed... 
Cytokines | Correlation analysis | Risk assessment | Rheumatoid arthritis | Ribonucleic acid--RNA | Cells | Polymorphism
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2012, Volume 13, Issue 1, pp. 44 - 50
Mouse invariant natural killer T cells (iNKT cells) provide cognate and noncognate help for lipid and protein-specific B cells, respectively. However, the... 
CXC CHEMOKINE RECEPTOR-5 | NKT CELLS | ACTIVATION | MARGINAL ZONE | IN-VIVO | IMMUNOGLOBULIN | DIFFERENTIATION | IMMUNOLOGY | ANTIBODY-RESPONSES | IL-21 | CUTTING EDGE | Polymerase chain reaction | Killer cells | Usage | Interleukin-21 | Physiological aspects | B cells | Research
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1827 - 1832
CD1d-restricted natural killer T (NKT) cells include two major subgroups. The most widely studied are Vα14Jα18⁺ invariant NKT (iNKT) cells that recognize the... 
T lymphocytes | Antigens | Reactivity | Natural killer T cells | Hybridomas | Antigen presenting cells | Lipids | Infections | Phospholipids | T cell antigen receptors | CD1 antigen presentation | Innate immunity | Adaptive immunity | Type II natural killer T cell | SULFATIDE | REPERTOIRE | POPULATION | ACTIVATION | MULTIDISCIPLINARY SCIENCES | DISTINCT | type II natural killer T cell | RECEPTOR | adaptive immunity | CD1 | innate immunity | KILLER T-CELLS | INNATE-LIKE | GLYCOLIPIDS | Hybridomas - metabolism | Corynebacterium glutamicum - genetics | Antigens, CD1d - immunology | Transferases (Other Substituted Phosphate Groups) - genetics | Antigens, Bacterial - immunology | Mycobacterium tuberculosis - immunology | Transferases (Other Substituted Phosphate Groups) - immunology | Cardiolipins - immunology | Galactosylceramides - metabolism | Receptors, Antigen, T-Cell, alpha-beta - immunology | Corynebacterium glutamicum - metabolism | Transferases (Other Substituted Phosphate Groups) - metabolism | Natural Killer T-Cells - metabolism | Myeloid Differentiation Factor 88 - immunology | Antigens, CD1d - genetics | Bacterial Proteins - immunology | Phospholipids - metabolism | Toll-Like Receptors - metabolism | Mycobacterium tuberculosis - metabolism | Phosphatidylglycerols - metabolism | Macrophages - immunology | Macrophages - microbiology | Cell Line | Antigen-Presenting Cells - metabolism | Mice, Inbred C57BL | Phosphatidylglycerols - immunology | Phospholipids - immunology | Toll-Like Receptors - immunology | Bacterial Proteins - genetics | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Cardiolipins - metabolism | Antigen-Presenting Cells - immunology | Antigens, CD1d - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Galactosylceramides - immunology | Hybridomas - immunology | Bacterial Proteins - metabolism | Mice | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Corynebacterium glutamicum - immunology | Antigens, Bacterial - metabolism | Myeloid Differentiation Factor 88 - metabolism | Natural Killer T-Cells - immunology | Autoimmunity | Killer cells | Antigen receptors, T cell | Receptors | Research | Properties | T cells | Biological Sciences | glycolipids | KazuyoshiKawakami | distinct | Mikrobiologi inom det medicinska området | VictorNizet | population | MoriyaTsuji | cd1 | receptor | Gurdyal S.Besra | Microbiology in the medical area | killer t-cells | innate-like | sulfatide | repertoire | KNizet | VBesra | GSTsuji | activation | Kawakami
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2014, Volume 111, Issue 37, p. 13433
  Invariant natural killer T (iNKT) cells are a specialized T-cell subset that recognizes lipids as antigens, contributing to immune responses in diverse... 
Antigens | Tissue | T cell receptors | Mammals | Fatty acids
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2012, Volume 109, Issue 52, p. 21354
  Intracellular recycling pathways play critical roles in internalizing membrane and fluid phase cargo and in balancing the inflow and outflow of membrane and... 
Antigen presentation | Membranes | Endocytosis | RNA-protein interactions | Cytoskeleton | Gene expression
Journal Article
Immunity, ISSN 1074-7613, 02/2017, Volume 46, Issue 2, pp. 220 - 232
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 07/2019, Volume 20, Issue 7, pp. 928 - 928
To define the cell populations that drive joint inflammation in rheumatoid arthritis (RA), we applied single-cell RNA sequencing (scRNA-seq), mass cytometry,... 
B-CELLS | PATHOGENESIS | SYSTEM | IMMUNE | MACROPHAGES | SUBSETS | IMMUNOLOGY | EXPRESSION | FIBROBLASTS | PATHOPHYSIOLOGY | T-Lymphocyte Subsets - immunology | Humans | Transcriptome | Autoimmunity - genetics | Synovial Membrane - pathology | Monocytes - metabolism | Monocytes - immunology | Leukocytes - immunology | Arthritis, Rheumatoid - metabolism | Flow Cytometry | Single-Cell Analysis - methods | Fibroblasts - metabolism | Computational Biology - methods | Gene Expression | Cross-Sectional Studies | Cytokines - metabolism | Signal Transduction | Gene Expression Profiling - methods | Workflow | Synovial Membrane - metabolism | Arthritis, Rheumatoid - pathology | Arthritis, Rheumatoid - genetics | Histocompatibility Antigens Class II - immunology | T-Lymphocyte Subsets - metabolism | Biomarkers | High-Throughput Nucleotide Sequencing | Histocompatibility Antigens Class II - genetics | Leukocytes - metabolism | Flow cytometry | Phenotypes | Populations | Pathogenesis | CD8 antigen | Lymphocytes T | Inflammation | Arthritis | Ribonucleic acid--RNA | Gene sequencing | Interleukin 6 | CD90 antigen | Monocytes | Biomedical materials | Lymphocytes B | Correlation analysis | Lymphocytes | Rheumatoid arthritis | Joints (anatomy) | Interleukin 1 | Fibroblasts | Biocompatibility | Histocompatibility antigen HLA | Osteoarthritis
Journal Article