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Nature Cell Biology, ISSN 1465-7392, 07/2017, Volume 19, Issue 7, pp. 844 - 855
Leukaemogenesis requires enhanced self-renewal, which is induced by oncogenes. The underlying molecular mechanisms remain incompletely understood. Here, we... 
RIBOSOMAL-RNA METHYLATION | BREAST-CANCER | BIOGENESIS | HEMATOPOIETIC STEM-CELLS | TRANSCRIPTION | GRANULOCYTIC DIFFERENTIATION | ACUTE MYELOID-LEUKEMIA | PROTEIN-SYNTHESIS | POLYMERASE-I | TRANSLATIONAL CONTROL | CELL BIOLOGY | Myeloid-Lymphoid Leukemia Protein - metabolism | Oncogene Proteins, Fusion - metabolism | Cell Proliferation | Leukemia - pathology | Humans | Leukemia - metabolism | RNA, Ribosomal - genetics | Protein Interaction Maps | Cell Self Renewal | RNA, Small Nucleolar - metabolism | Time Factors | Cell Transformation, Neoplastic - genetics | U937 Cells | HEK293 Cells | Ribonucleoproteins - genetics | DEAD-box RNA Helicases - metabolism | Leukemia - genetics | Repressor Proteins - metabolism | Genetic Predisposition to Disease | Core Binding Factor Alpha 2 Subunit - metabolism | Signal Transduction | Mice, Inbred C57BL | RNA, Ribosomal - metabolism | Repressor Proteins - genetics | Ribonucleoproteins - metabolism | Gene Expression Regulation, Leukemic | Transcription Factors - genetics | Cell Transformation, Neoplastic - metabolism | Proto-Oncogene Proteins c-myc - metabolism | RNA, Small Nucleolar - genetics | Mice, Knockout | RUNX1 Translocation Partner 1 Protein | Transcription Factors - metabolism | DEAD-box RNA Helicases - genetics | Phenotype | Animals | Myeloid-Lymphoid Leukemia Protein - genetics | Oncogene Proteins, Fusion - genetics | K562 Cells | HL-60 Cells | Proto-Oncogene Proteins c-myc - genetics | Cell Transformation, Neoplastic - pathology | Methylation | Core Binding Factor Alpha 2 Subunit - genetics | Enhancer-of-split protein | Leukemia | rRNA | Myc protein | snoRNA | DNA helicase | AML1 protein | Molecular modelling | Clonal deletion | Ribonucleic acids | Stem cells | Deletion | In vitro methods and tests | RNA helicase
Journal Article
Blood, ISSN 0006-4971, 10/2013, Volume 122, Issue 14, pp. 2433 - 2442
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 776 - 776
Abstract The transcription factor CCAAT enhancer binding protein alpha (C/EBPα) is a master regulator of granulopoiesis and is silenced in approximately 50% of... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 3558 - 3558
Abstract Almost one tenth of acute myeloid leukemias (AML) are related to t(15;17) translocation. This aberration leads to the PML-RARα fusion protein, which... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 3814 - 3814
Abstract ABR (Active BCR-related) is the only protein in humans and mice closely homologous to BCR. BCR acts as a tumor suppressor in different cancers, such... 
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 3514 - 3514
Abstract Abstract 3514 The transcription factor CCAAT Enhancer Binding Protein alpha (C/EBPα) is crucial for normal granulopoiesis and frequently disrupted in... 
Journal Article
Monatsschrift Kinderheilkunde, ISSN 0026-9298, 6/2012, Volume 160, Issue 6, pp. 579 - 581
Die Pylorusagenesie ist mit einer Prävalenz von 1:100.000 Neugeborenen eine sehr seltene angeborene Fehlbildung des Gastrointestinaltrakts. Im vorliegenden... 
Pediatrics | Agenesis | Single-bubble phenomenon | Medicine & Public Health | Atresie | Angeborene Fehlbildung | Congenital malformation | Pylorus | General Practice / Family Medicine | Atresia | Single bubble“-Phänomen | Agenesie
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 2368 - 2368
Abstract Abstract 2368 The transcription factor CCAAT Enhancer Binding Protein alpha (C/EBPα) is crucial for normal granulopoiesis and frequently disrupted in... 
Journal Article
Monatsschrift Kinderheilkunde, ISSN 0026-9298, 06/2012, Volume 160, Issue 6, p. 579
Die Pylorusagenesie ist mit einer Pravalenz von 1:100.000 Neugeborenen eine sehr seltene angeborene Fehlbildung des Gastrointestinaltrakts. Im vorliegenden... 
Genetic disorders | Gastrointestinal system | Birth defects
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e68522
Journal Article
The Cerebellum, ISSN 1473-4222, 2/2014, Volume 13, Issue 1, pp. 89 - 96
Journal Article