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07/2017
resumo patente de invenção: "características da ponta distal para atuador de extremidade de instrumento cirúrgico". a presente invenção refere-se a um aparelho... 
SURGERY | DIAGNOSIS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | IDENTIFICATION
Patent
05/2016
An apparatus comprises a body, a shaft, and an end effector that is operable to compress, staple, and cut tissue. The end effector comprises and anvil and a... 
SURGERY | DIAGNOSIS | HYGIENE | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | IDENTIFICATION
Patent
The New England Journal of Medicine, ISSN 0028-4793, 10/2015, Volume 373, Issue 17, pp. 1627 - 1639
Journal Article
Mastozoología neotropical, ISSN 1666-0536, 12/2006, Volume 13, Issue 2, pp. 251 - 254
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2018, Volume 379, Issue 21, pp. 2027 - 2039
In a randomized trial involving patients with ALK -rearranged lung cancer, brigatinib was associated with longer progression-free survival and more activity... 
MEDICINE, GENERAL & INTERNAL | CERITINIB | EML4-ALK FUSION GENE | RESISTANCE | OPEN-LABEL | KINASE INHIBITOR | SINGLE-ARM | EGFR | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - chemistry | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Brain Neoplasms - secondary | Carcinoma, Non-Small-Cell Lung - secondary | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Organophosphorus Compounds - adverse effects | Crizotinib - therapeutic use | Lung Neoplasms - chemistry | Anaplastic Lymphoma Kinase - analysis | Kaplan-Meier Estimate | Organophosphorus Compounds - therapeutic use | Crizotinib - adverse effects | Pyrimidines - therapeutic use | Progression-Free Survival | Pyrimidines - adverse effects | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Anaplastic Lymphoma Kinase - antagonists & inhibitors | Crizotinib | Cancer patients | Safety and security measures | Development and progression | Dosage and administration | Comparative analysis | Lung cancer, Non-small cell | Drug therapy | Health aspects | Nuclear magnetic resonance--NMR | Medical imaging | Statistical analysis | Lung cancer | Non-small cell lung carcinoma | Metastasis | Radiation therapy | Lymphoma | Cancer therapies | Chemotherapy | Technical communication | Mutation | Protein-tyrosine kinase | Drug dosages | Pharmaceuticals
Journal Article
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 7, pp. 976 - 983
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3196 - 15
The biological determinants of sensitivity and resistance to immune checkpoint blockers are not completely understood. To elucidate the role of intratumoral... 
CTLA-4 BLOCKADE | PD-1 BLOCKADE | MULTIDISCIPLINARY SCIENCES | MUTATIONAL LANDSCAPE | NEOANTIGENS | NIVOLUMAB | IDENTIFICATION | CANCER | T-CELLS | IPILIMUMAB | LYMPHOCYTES | Humans | Lung Neoplasms - pathology | Male | Antibodies, Blocking - pharmacology | Histocompatibility Antigens Class I - metabolism | Lymphocyte Activation - immunology | Cytotoxicity, Immunologic - drug effects | Carcinoma, Non-Small-Cell Lung - pathology | Amino Acid Sequence | Reproducibility of Results | Peptides - chemistry | Carcinogenesis - genetics | Programmed Cell Death 1 Receptor - metabolism | Lymphocytes, Tumor-Infiltrating - drug effects | Mice, SCID | Mutation - genetics | Carcinogenesis - drug effects | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Phenotype | Tobacco | Animals | Lymphocytes, Tumor-Infiltrating - pathology | Mutant Proteins - chemistry | Survival Analysis | Mice, Inbred NOD | Cell Proliferation - drug effects | Lymphocytes, Tumor-Infiltrating - immunology | Cell proliferation | Phenotypes | Small cell lung carcinoma | PD-1 protein | Xenotransplantation | Non-small cell lung carcinoma | Lymphocytes T | CD3 antigen | Lung carcinoma | Patients | Gene sequencing | Immune checkpoint | Lymphocytes | Xenografts | Pretreatment | Immunofluorescence | Deoxyribonucleic acid--DNA | DNA sequencing | Tumors
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 12, pp. 1683 - 1696
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 11/2014, Volume 515, Issue 7528, pp. 563 - 567
Journal Article