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index medicus (33) 33
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1. Full Text DNA methylation analysis from blood spots: Increasing yield and quality for genome-wide and locus-specific methylation analysis
by Ghantous, Akram and Hernandez-Vargas, Hector and Herceg, Zdenko
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1708, pp. 605 - 619
Blood represents an easily accessible human tissue for numerous research and clinical applications, including surrogate roles for biomarkers of other tissues.... 
Whole bisulfitome amplification | DNA extraction | Illumina HM450 arrays | Pyrosequencing | DNA methylation | Epigenetics | Blood spot | DNA - isolation & purification | DNA Methylation | Epigenomics | Dried Blood Spot Testing - methods | Humans | DNA - standards | High-Throughput Nucleotide Sequencing | Neonatal Screening - methods | Blood Specimen Collection - methods | Infant, Newborn | Whole Genome Sequencing | Index Medicus
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2. Full Text DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
by Joubert, Bonnie R and Felix, Janine F and Yousefi, Paul and Bakulski, Kelly M and Just, Allan C and Breton, Carrie and Reese, Sarah E and Markunas, Christina A and Richmond, Rebecca C and Xu, Cheng-Jian and Xu, Zongli and Küpers, Leanne K and Oh, Sam S and Hoyo, Cathrine and Gruzieva, Olena and Söderhäll, Cilla and Salas, Lucas A and Baïz, Nour and Zhang, Hongmei and Lepeule, Johanna and Ruiz, Carlos and Ligthart, Symen and Wang, Tianyuan and Taylor, Jack A and Duijts, Liesbeth and Sharp, Gemma C and Jankipersadsing, Soesma A and Nilsen, Roy M and Vaez, Ahmad and Fallin, M. Daniele and Hu, Donglei and Litonjua, Augusto A and Fuemmeler, Bernard F and Huen, Karen and Kere, Juha and Kull, Inger and Munthe-Kaas, Monica Cheng and Gehring, Ulrike and Bustamante, Mariona and Saurel-Coubizolles, Marie José and Quraishi, Bilal M and Ren, Jie and Tost, Jörg and Gonzalez, Juan R and Peters, Marjolein J and Håberg, Siri E and van Meurs, Joyce B and Gaunt, Tom R and Kerkhof, Marjan and Corpeleijn, Eva and Feinberg, Andrew P and Eng, Celeste and Baccarelli, Andrea A and Benjamin Neelon, Sara E and Bradman, Asa and Merid, Simon Kebede and Bergström, Anna and Herceg, Zdenko and Hernandez-Vargas, Hector and Brunekreef, Bert and Pinart, Mariona and Heude, Barbara and Ewart, Susan and Yao, Jin and Lemonnier, Nathanaël and Franco, Oscar H and Wu, Michael C and Hofman, Albert and McArdle, Wendy and Van der Vlies, Pieter and Falahi, Fahimeh and Gillman, Matthew W and Barcellos, Lisa F and Kumar, Ashish and Wickman, Magnus and Guerra, Stefano and Charles, Marie-Aline and Holloway, John and Auffray, Charles and Tiemeier, Henning W and Smith, George Davey and Postma, Dirkje and Hivert, Marie-France and Eskenazi, Brenda and Vrijheid, Martine and Arshad, Hasan and Antó, Josep M and Dehghan, Abbas and Karmaus, Wilfried and Annesi-Maesano, Isabella and Sunyer, Jordi and Ghantous, Akram and Pershagen, Göran and Holland, Nina and Murphy, Susan K and DeMeo, Dawn L and Burchard, Esteban G and Ladd-Acosta, Christine and Snieder, Harold and Nystad, Wenche and ...
The American Journal of Human Genetics, ISSN 0002-9297, 04/2016, Volume 98, Issue 4, pp. 680 - 696
Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy... 
BREAST-CANCER | IN-UTERO | CIGARETTE-SMOKING | LYMPH-NODE METASTASIS | PRENATAL EXPOSURE | TOBACCO-SMOKING | GENETICS & HEREDITY | LUNG-FUNCTION DECLINE | NEUROPILIN-2 EXPRESSION | AUTISM SPECTRUM DISORDERS | POSTSYNAPTIC DENSITY | Smoking - adverse effects | European Continental Ancestry Group - genetics | Genetic Association Studies | Epigenesis, Genetic | Humans | Child, Preschool | Infant | Chromosome Mapping | Cleft Palate - genetics | Asthma - genetics | Pregnancy | Cleft Lip - genetics | DNA Methylation | Cleft Palate - etiology | Female | Asthma - etiology | Child | Infant, Newborn | Cleft Lip - etiology | Genome-wide association studies | Genetic aspects | Nucleotide sequencing | Methylation | Health aspects | Methods | DNA sequencing | Smoking | Newborn babies | DNA methylation | Genomes | Mothers | Meta-analysis | Index Medicus
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3. Full Text Associations of semen quality with non-essential heavy metals in blood and seminal fluid: data from the Environment and Male Infertility (EMI) study in Lebanon
by Sukhn, Carol and Awwad, Johnny and Ghantous, Akram and Zaatari, Ghazi
Journal of Assisted Reproduction and Genetics, ISSN 1058-0468, 9/2018, Volume 35, Issue 9, pp. 1691 - 1701
Human exposure to environmental pollutants is widespread. It was suggested that exposure to non-essential heavy metals may adversely affect semen development... 
Human Genetics | Medicine & Public Health | Environmental pollution | Gynecology | Non-essential heavy metals | Male infertility | Semen quality | Reproductive Medicine | REPRODUCTIVE ENDOCRINE FUNCTION | OBSTETRICS & GYNECOLOGY | DIABETES-MELLITUS | REPRODUCTIVE BIOLOGY | PLASMA | CADMIUM | SPERM | ADULT-RAT | MEN | GENETICS & HEREDITY | DEPLETED URANIUM | EXPOSURE | LEAD | Fertility clinics | Barium | Uranium | Arsenic | Infertility, Male | Pollutants | Mass spectrometry | Heavy metals | Quality management | Cadmium | Seminal fluid | Motility | Sperm | Semen | Xenotransplantation | Mass spectroscopy | Blood | Infertility | Quality | Morphology | Lead | Mercury | Index Medicus | Reproductive Physiology and Disease
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4. Full Text Epigenetic supersimilarity of monozygotic twin pairs
by van Baak, Timothy E and Coarfa, Cristian and Dugué, Pierre-Antoine and Fiorito, Giovanni and Laritsky, Eleonora and Baker, Maria S and Kessler, Noah J and Dong, Jianrong and Duryea, Jack D and Silver, Matt J and Saffari, Ayden and Prentice, Andrew M and Moore, Sophie E and Ghantous, Akram and Routledge, Michael N and Gong, Yun Yun and Herceg, Zdenko and Vineis, Paolo and Severi, Gianluca and Hopper, John L and Southey, Melissa C and Giles, Graham G and Milne, Roger L and Waterland, Robert A
Genome Biology, ISSN 1474-7596, 01/2018, Volume 19, Issue 1, pp. 2 - 2
Background: Monozygotic twins have long been studied to estimate heritability and explore epigenetic influences on phenotypic variation. The phenotypic and... 
Metastable epialleles | DOHaD | Epigenetics | Developmental programming | Dizygotic | Monozygotic | Twins | Cancer | DNA METHYLATION | PERIPHERAL-BLOOD | WIDE METHYLATION | HERITABILITY | MULTIPLE TISSUES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DISEASE | GENETICS & HEREDITY | GENE-EXPRESSION | EPIGENOME | NORMALIZATION | INHERITANCE | DNA Methylation | Neoplasms - genetics | Twins, Monozygotic - genetics | Epigenesis, Genetic | Humans | Twins, Dizygotic | CpG Islands | Models, Genetic | Genome, Human | DNA - blood | Disease | Phenotypic variations | Data processing | Genomes | Breast cancer | Gene expression | Consortia | Embryogenesis | DNA methylation | Heritability | Methylation | Bioinformatics | Deoxyribonucleic acid--DNA | Index Medicus
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5. Full Text Genome‐wide profiling of normal gastric mucosa identifies Helicobacter pylori‐ and cancer‐associated DNA methylome changes
by Woo, Hae Dong and Fernandez‐Jimenez, Nora and Ghantous, Akram and Degli Esposti, Davide and Cuenin, Cyrille and Cahais, Vincent and Choi, Il Ju and Kim, Young‐Il and Kim, Jeongseon and Herceg, Zdenko
International Journal of Cancer, ISSN 0020-7136, 08/2018, Volume 143, Issue 3, pp. 597 - 609
The large geographic variations in the incidence of gastric cancer (GC) are likely due to differential environmental exposures, in particular to Helicobacter... 
H. pylori | gastric cancer | methylation profiling | epigenetic memory | biomarkers of cancer risk | CELLS | SUSCEPTIBILITY | RISK | MECHANISMS | KOREA | CARCINOGENESIS | ONCOLOGY | METHYLATION PATTERNS | GENES | INFECTION | EPIGENOME | Epigenetic inheritance | Oncology, Experimental | Genomics | Development and progression | Research | Genetic polymorphisms | Quantitative genetics | Helicobacter pylori | Analysis | DNA | Helicobacter infections | Genetic aspects | Methylation | Cancer | Profiling | Mucosa | Gastric mucosa | Health risks | Risk | Infections | Genomes | Genetic diversity | Leukocytes | Geographical variations | Mucous membrane | Quantitative trait loci | White blood cells | Peripheral blood | DNA methylation | Biomarkers | Bioindicators | Gastric cancer | Deoxyribonucleic acid--DNA | Tumors | Polymorphism | Index Medicus
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6. Full Text The association between birth order and childhood leukemia may be modified by paternal age and birth weight. Pooled results from the International Childhood Cancer Cohort Consortium (I4C)
by Paltiel, Ora and Lemeshow, Stanley and Phillips, Gary S and Tikellis, Gabriella and Linet, Martha S and Ponsonby, Anne‐Louise and Magnus, Per and Håberg, Siri E and Olsen, Sjurdur F and Granström, Charlotta and Klebanoff, Mark and Golding, Jean and Herceg, Zdenko and Ghantous, Akram and Hirst, Jane Elizabeth and Borkhardt, Arndt and Ward, Mary H and Holst Søegaard, Signe and Dwyer, Terence
International Journal of Cancer, ISSN 0020-7136, 01/2019, Volume 144, Issue 1, pp. 26 - 33
The “delayed infection hypothesis” states that a paucity of infections in early childhood may lead to higher risks of childhood leukemia (CL), especially acute... 
cohort studies | birth weight | paternal age | childhood leukemia | acute lymphoblastic leukemia | birth order | POPULATION | INFECTIONS | LENGTH | RISK | CHILDREN | ONCOLOGY | NATIONWIDE | ACUTE LYMPHOBLASTIC-LEUKEMIA | GROWTH | EXPOSURE | Research | Leukemia in children | Analysis | Oncology, Experimental | Cancer | Statistical analysis | Acute lymphatic leukemia | Leukemia | Birth order | Hazards | Exposure | Infections | Lymphatic leukemia | Risk factors | Weight | Consortia | Confidence intervals | Statistical models | Birth weight | Children | Health risk assessment | Age | Index Medicus
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7. Full Text Oxidative stress and inflammation mediate the effect of air pollution on cardio‐ and cerebrovascular disease: A prospective study in nonsmokers
by Fiorito, Giovanni and Vlaanderen, Jelle and Polidoro, Silvia and Gulliver, John and Galassi, Claudia and Ranzi, Andrea and Krogh, Vittorio and Grioni, Sara and Agnoli, Claudia and Sacerdote, Carlotta and Panico, Salvatore and Tsai, Ming‐Yi and Probst‐Hensch, Nicole and Hoek, Gerard and Herceg, Zdenko and Vermeulen, Roel and Ghantous, Akram and Vineis, Paolo and Naccarati, Alessio and Vogel, U and EXPOsOMICS Consortium and EXPOsOMICS consortium
Environmental and Molecular Mutagenesis, ISSN 0893-6692, 04/2018, Volume 59, Issue 3, pp. 234 - 246
Air pollution is associated with a broad range of adverse health effects, including mortality and morbidity due to cardio‐ and cerebrovascular diseases (CCVD),... 
cytokine signaling | air pollution | cerebrovascular diseases | cardiovascular diseases | inflammation | oxidative stress | USE REGRESSION-MODELS | LONG-TERM EXPOSURE | RISK | SMOKING | CANCER | DNA-METHYLATION | F2RL3 METHYLATION | ENVIRONMENTAL STRESSORS | ENVIRONMENTAL SCIENCES | GENETICS & HEREDITY | CARDIOVASCULAR-DISEASE | TOXICOLOGY | ADULT ASTHMA | Prognosis | Prospective Studies | Oxidative Stress | Humans | Middle Aged | Air Pollution - adverse effects | Male | Cerebrovascular Disorders - metabolism | Case-Control Studies | Incidence | Inflammation - complications | Inflammation - metabolism | Cardiovascular Diseases - epidemiology | Adult | Female | Cerebrovascular Disorders - epidemiology | Retrospective Studies | Cardiovascular Diseases - etiology | Cardiovascular Diseases - metabolism | Biomarkers - analysis | Cerebrovascular Disorders - etiology | Environmental Exposure - adverse effects | Italy - epidemiology | Aged | Smoking | Proteins | Medical research | Oxidative stress | Interleukins | Analysis | Mortality | Genomics | Medicine, Experimental | Air pollution | Inflammation | Pollutants | Methylation | Enrichment | Reactive oxygen species | Interleukin | Cytotoxicity | Risk | Genomes | Blood | Chronic exposure | Signal transduction | Pollution | Vascular diseases | Pollution effects | DNA methylation | Bioindicators | Diagnosis | Cerebrovascular diseases | Deoxyribonucleic acid--DNA | Glutathione | Cytokines | Health risks | Exposure | Disease control | Environmental risk | Morbidity | Signaling | Air pollution measurements | Molecular modelling | Biomarkers | Nitrogen dioxide | Index Medicus
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8. Full Text DNA Methylome Marks of Exposure to Particulate Matter at Three Time Points in Early Life
by Plusquin, Michelle and Chadeau-Hyam, Marc and Ghantous, Akram and Alfano, Rossella and Bustamante, Mariona and Chatzi, Leda and Cuenin, Cyrille and Gulliver, John and Herceg, Zdenko and Kogevinas, Manolis and Nawrot, Tim S and Pizzi, Costanza and Porta, Daniela and Relton, Caroline L and Richiardi, Lorenzo and Robinson, Oliver and Sunyer, Jordi and Vermeulen, Roel and Vriens, Annette and Vrijheid, Martine and Henderson, John and Vineis, Paolo
Environmental Science and Technology, ISSN 0013-936X, 05/2018, Volume 52, Issue 9, pp. 5427 - 5437
Maternal exposure to airborne particulate matter (PM) has been associated with restricted fetal growth and reduced birthweight. Here, we performed... 
COHORT PROFILE | ENVIRONMENTAL SCIENCES | METHYLATION | PRENATAL EXPOSURE | ENGINEERING, ENVIRONMENTAL | LOW-BIRTH-WEIGHT | USE REGRESSION-MODELS | CORD BLOOD | NEWBORNS | AMBIENT AIR-POLLUTION | MATERNAL SMOKING | PREGNANCY | N-Acetylglucosamine | Airborne particulates | p53 Protein | Fetuses | Particulates | Exposure | Blood | Studies | Pregnancy | Consortia | γ-Aminobutyric acid | Epidermal growth factor | Cord blood | Correlation analysis | Particulate matter | DNA methylation | Birth weight | Children | Methylation | Age | Particulate emissions | Deoxyribonucleic acid--DNA | CpG islands
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9. Full Text Sesquiterpene lactones isolated from indigenous Middle Eastern plants inhibit tumor promoter-induced transformation of JB6 cells
by Saikali, Melody and Ghantous, Akram and Halawi, Racha and Talhouk, Salma N and Saliba, Najat A and Darwiche, Nadine
BMC Complementary and Alternative Medicine, ISSN 1472-6882, 07/2012, Volume 12, Issue 1, pp. 89 - 89
Background: Sesquiterpene lactones (SL) are plant secondary metabolites that are known for their anti-fungal, anti-bacterial, anti-inflammatory, and anti-tumor... 
TRANSCRIPTION FACTORS | MOLECULAR TARGETS | CENTAUREA-AINETENSIS | INTEGRATIVE & COMPLEMENTARY MEDICINE | MOUSE EPIDERMAL-CELLS | SKIN CARCINOGENESIS | ANTICANCER DRUGS | NF-KAPPA-B | NEOPLASTIC TRANSFORMATION | ANCHORAGE INDEPENDENCE | AP-1 | Sesquiterpenes - isolation & purification | Heterocyclic Compounds, 3-Ring - pharmacology | Plant Extracts - pharmacology | Transcriptional Activation - drug effects | NF-kappa B - metabolism | Centaurea - chemistry | Transcription Factor AP-1 - metabolism | Lactones - pharmacology | Sesquiterpenes - therapeutic use | Middle East | Heterocyclic Compounds, 3-Ring - isolation & purification | Skin Neoplasms - prevention & control | Phytotherapy | Anticarcinogenic Agents - pharmacology | Anticarcinogenic Agents - isolation & purification | Anticarcinogenic Agents - therapeutic use | Cell Line | Lactones - isolation & purification | Signal Transduction | Plant Extracts - isolation & purification | Lactones - therapeutic use | Skin Neoplasms - metabolism | Animals | Keratinocytes - drug effects | Keratinocytes - metabolism | Achillea - chemistry | Heterocyclic Compounds, 3-Ring - therapeutic use | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Cell Transformation, Neoplastic - drug effects | Sesquiterpenes - pharmacology | Plant Extracts - therapeutic use | Care and treatment | DNA binding proteins | Carcinogenesis | Plant metabolites | Cancer | Lactones | Studies | Nuclear magnetic resonance--NMR | Epigenetics | Amino acids | Flowers & plants | Kinases | Cancer therapies | Manuscripts | Apoptosis | Index Medicus
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10. Full Text Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
by Kupers, LK and Monnereau, C and Sharp, GC and Yousefi, P and Salas, LA and Ghantous, A and Page, CM and Reese, SE and Wilcox, AJ and Czamara, D and Starling, AP and Novoloaca, A and Lent, S and Roy, R and Hoyo, C and Breton, CV and Allard, C and Just, AC and Bakulski, KM and Holloway, JW and Everson, TM and Xu, CJ and Huang, RC and van der Plaat, DA and Wielscher, M and Merid, SK and Ullemar, V and Rezwan, FI and Lahti, J and van Dongen, J and Langie, SAS and Richardson, TG and Magnus, MC and Nohr, EA and Xu, ZL and Duijts, L and Zhao, SS and Zhang, WM and Plusquin, M and DeMeo, DL and Solomon, O and Heimovaara, JH and Jima, DD and Gao, L and Bustamante, M and Perron, P and Wright, RO and Hertz-Picciotto, I and Zhang, HM and Karagas, MR and Gehring, U and Marsit, CJ and Beilin, LJ and Vonk, JM and Jarvelin, MR and Bergstrom, A and Ortqvist, AK and Ewart, S and Villa, PM and Moore, SE and Willemsen, G and Standaert, ARL and Haberg, SE and Sorensen, TIA and Taylor, JA and Raikkonen, K and Yang, IV and Kechris, K and Nawrot, TS and Silver, MJ and Gong, YY and Richiardi, L and Kogevinas, M and Litonjua, AA and Eskenazi, B and Huen, K and Mbarek, H and Maguire, RL and Dwyer, T and Vrijheid, M and Bouchard, L and Baccarelli, AA and Croen, LA and Karmaus, W and Anderson, D and de Vries, M and Sebert, S and Kere, J and Karlsson, R and Arshad, SH and Hamalainen, E and Routledge, MN and Boomsma, DI and Feinberg, AP and Newschaffer, CJ and Govarts, E and Moisse, M and Fallin, MD and Melen, E and Prentice, AM and ...
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1893 - 1893
Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide... 
FETAL ORIGINS | EPIGENETIC MEDIATION | PACKAGE | MULTIDISCIPLINARY SCIENCES | CORD BLOOD | DISEASE | MENDELIAN RANDOMIZATION | GENETIC-EVIDENCE | MATERNAL SMOKING | PREGNANCY | BIOCONDUCTOR | Index Medicus | DNA methylation | Epigenetics | Paediatric research | Epidemiology | Nutrition and Disease | Diervoeding | Leerstoelgroep Diervoeding | HNE Nutrition and Disease | Chair Nutrition and Disease | Voeding en Ziekte | Animal Nutrition | HNE Voeding en Ziekte
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11. Full Text Genome-wide profiling of normal gastric mucosa identifies Helicobacter pylori - and cancer-associated DNA methylome changes
: Methylation profiling of normal gastric mucosa
by Woo, Hae Dong and Fernandez-Jimenez, Nora and Ghantous, Akram and Degli Esposti, Davide and Cuenin, Cyrille and Cahais, Vincent and Choi, Il Ju and Kim, Young-Il and Kim, Jeongseon and Herceg, Zdenko
International Journal of Cancer, ISSN 0020-7136, 08/2018, Volume 143, Issue 3, pp. 597 - 609
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12. Full Text DNA methylation in inflammatory pathways modifies the association between BMI and adult-onset non-atopic Asthma
by Jeong, Ayoung and Imboden, Medea and Ghantous, Akram and Novoloaca, Alexei and Carsin, Anne-Elie and Kogevinas, Manolis and Schindler, Christian and Lovison, Gianfranco and Herceg, Zdenko and Cuenin, Cyrille and Vermeulen, Roel and Jarvis, Deborah and Amaral, André F. S and Kronenberg, Florian and Vineis, Paolo and Probst-Hensch, Nicole
International Journal of Environmental Research and Public Health, ISSN 1661-7827, 02/2019, Volume 16, Issue 4, p. 600
A high body mass (BMI) index has repeatedly been associated with non-atopic asthma, but the biological mechanism linking obesity to asthma is still poorly... 
Obesity | DNA methylation | Epigenetics | Innate immunity | Epigenome-wide association study | Inflammation | Adult-onset asthma | Non-atopic asthma | non-atopic asthma | epigenome-wide association study | adult-onset asthma | PHENOTYPES | epigenetics | CLUSTER-ANALYSIS | VARIABILITY | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | innate immunity | inflammation | BODY-MASS INDEX | HEALTH | obesity | Index Medicus
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