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by Nanka, O and Krejci, E and Pesevski, Z and Sedmera, D and Smart, N and Rossdeutsch, A and Dube, K. N and Riegler, J and Price, A. N and Taylor, A and Muthurangu, V and Turner, M and Lythgoe, M. F and Riley, P. R and Kryvorot, S and Vladimirskaya, T and Shved, I and Schwarzl, M and Seiler, S and Huber, S and Steendijk, P and Maechler, H and Truschnig-Wilders, M and Pieske, B and Post, H and Caprio, C and Baldini, A and Chiavacci, E and Dolfi, L and Verduci, L and Meghini, F and Cremisi, F and Pitto, L and Kuan, T.-C and Chen, M.-C and Yang, T.-H and Wu, W.-T and Lin, C. S and Rai, H and Kumar, S and Sharma, A. K and Mastana, S and Kapoor, A and Pandey, C. M and Agrawal, S and Sinha, N and Orlowska-Baranowska, E. H and Placha, G and Gora, J and Baranowski, R and Abramczuk, E and Hryniewiecki, T and Gaciong, Z and Verschuren, J. J. W and Wessels, J. A. M and Trompet, S and Stott, D. J and Sattar, N and Buckley, B and Guchelaar, H. J and Jukema, J. W and Gharanei, M and Hussain, A and Mee, C. J and Maddock, H. L and Wijnen, W. J and Van Den Oever, S and Van Der Made, I and Hiller, M and Tijsen, A. J and Pinto, Y. M and Creemers, E. E and Nikulina, S. U. Y and Chernova, A and Petry, A and Rzymski, T and Kracun, D and Riess, F and Pike, L and Harris, A. L and Gorlach, A and Katare, R and Oikawa, A and Riu, F and Beltrami, A. P and Cesseli, D and Emanueli, C and Madeddu, P and Zaglia, T and Milan, G and Franzoso, M and Pesce, P and Sarais, C and Sandri, M and Mongillo, M and Butler, T. J and Seymour, A.-M. L and Ashford, D and Jaffre, F and Bussen, M and ...
Cardiovascular Research, ISSN 0008-6363, 03/2012, Volume 93, Issue suppl 1, pp. S92 - S127
Journal Article
by Schlueter, J and Brand, T and Henderson, D. J and Boczonadi, V and Humbert, P and Chaudhry, B and Sedmera, D and Svatunkova, J and Kockova, R and Sankova, B and Lopez Sanchez, C and Franco, D and Aranega, A and Garcia-Martinez, V and Demina, E and Miroshikova, V and Denisenko, A and Schwarzman, A and Sanchez-Cabo, F and Torroja, C and Benguria, A and Buchan, R and Srivastava, P and Martinez, F and Barton, P and Cook, S and Dopazo, A and Lara-Pezzi, E and Rai, H and Kumar, S and Sharma, A. K and Mastana, S and Kapoor, A and Pandey, C. M and Agrawal, S and Sinha, N and Lipkova, J and Goldbergova, M and Parenica, J and Bienertova Vasku, J and Vasku, A and Kala, P and Spinar, J and Perez-Cabornero, L and Cantalapiedra, D and Forteza, A and Saez-Villaverde, R and Zumalde, J and Fernandez-Pedrosa, V and Zuniga-Trejos, S and Gil-Borja, M and Lazaro, M and Santillan, S and Costa, M and Cortez-Dias, N and Carrilho-Ferreira, P and Silva, D and Jorge, C and Placido, R and Calisto, C and Fiuza, M and Nunes Diogo, A and Enguita, F. J and Sillje, H. H. W and Lu, B and Yu, H and Zwartbol, M and Ruifrok, W. P and Van Gilst, W. H and De Boer, R. A and Zaliaduonyte-Peksiene, D and Simonyte, S and Lesauskaite, V and Vaskelyte, J and Mizariene, V and Zaliunas, R and Tigchelaar, W and Barlaka, E and Lazou, A and Del Giudice, C and Cipolletta, E and Anastasio, A and Santulli, G and Rusciano, M and Maione, A. S and Campiglia, P and Illario, M and Trimarco, B and Iaccarino, G and Frentzou, G. A and Drinkhill, M. J and Turner, N. A and Ball, S. G and Ainscough, J. F. X and Bertrand, L and Mailleux, F and Hammond, J and Ginion, A and Hue, L and Balligand, J. L and ...
Cardiovascular Research, ISSN 0008-6363, 03/2012, Volume 93, Issue suppl 1, pp. S9 - S45
Journal Article
Journal Article
Heart, ISSN 1355-6037, 01/2014, Volume 100, Issue Suppl 1, pp. A7 - A8
Tyrosine Kinase inhibitor Sunitinib mediates its apoptotic anti-cancer effects by inhibiting intracellular signalling involved in tumour angiogenesis and cell... 
Journal Article
Heart, ISSN 1355-6037, 12/2011, Volume 97, Issue 24, pp. e8 - e8
IntroductionDespite the importance of anthracycline antibiotics such as Doxorubicin in anticancer pharmacology, their clinical value is jeopardised by their... 
Journal Article
Heart, ISSN 1355-6037, 01/2014, Volume 100, Issue Suppl 1, pp. A6 - A6
Doxorubicin is one of the most effective anti-cancer agents. However, its use is associated with adverse cardiac effects, including cardiomyopathy and... 
Journal Article
Heart, ISSN 1355-6037, 01/2011, Volume 97, Issue 1, pp. e1 - e1
Drug-induced cardiotoxicity is a major concern to the pharmacological industry and it is one of the main reasons for non-approval, re-labelling, warnings and... 
Journal Article
Heart, ISSN 1355-6037, 12/2011, Volume 97, Issue 24, pp. e8 - e8
  β-Adrenoceptors agonists such as Salbutamol and Salmeterol are bronchodilators used to alleviate the symptoms of asthma. Recent clinical studies have... 
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 04/2013, Volume 268, Issue 2, pp. 149 - 156
Chemotherapeutic agents such as doxorubicin are known to cause or exacerbate cardiovascular cell death when an underlying heart condition is present. However,... 
Ischaemia | Cyclophilin D | Anthracycline | Mitochondrial permeability transition pore | Cyclosporin A | Doxorubicin | Reperfusion injury | Cancer | MEMBRANE PERMEABILITY | OXIDATIVE STRESS | ISOLATED RAT HEARTS | INDUCED CARDIOMYOPATHY | ANTITUMOR-ACTIVITY | CYCLOSPORINE-A PROTECTS | INDUCED CARDIOTOXICITY | CHILDHOOD-CANCER | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CONGESTIVE-HEART-FAILURE | Antibiotics, Antineoplastic - toxicity | Myocardial Reperfusion Injury - complications | Myocardial Contraction - drug effects | Rats | Male | Mitochondrial Membrane Transport Proteins - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | Rats, Sprague-Dawley | Doxorubicin - toxicity | Animals | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - metabolism | Hemodynamics - drug effects | Oxidative Stress - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Adenosine | Anthracyclines | Chemotherapy | Polyvinylidene fluoride | Analysis | Cytochrome P-450 | Cyanides | Permeability | Cyclosporine | Muscle proteins | Adenosine triphosphate | Index Medicus | Drugs | Heart | Oxidative stress | Cardiac muscle | Confocal microscopy | Data processing | Muscle contraction | Western blotting | cardiomyocytes | Reperfusion | Ischemia | Cell death | MPTP | Injuries | APOPTOSIS | PERMEABILITY | DOXORUBICIN | MITOCHONDRIA | RATS | 60 APPLIED LIFE SCIENCES | HEART | OXYGEN | DEPOLARIZATION | ANOXIA | ATP | ADENINES | CYCLOSPORINE
Journal Article
Journal Article
Heart, ISSN 1355-6037, 12/2011, Volume 97, Issue 24, p. e8
β-Adrenoceptors agonists such as Salbutamol and Salmeterol are bronchodilators used to alleviate the symptoms of asthma. Recent clinical studies have... 
Journal Article
Minerva Endocrinologica, ISSN 0391-1977, 09/2017, Volume 42, Issue 3, pp. 248 - 270
Journal Article
2013
Doxorubicin is one of the most effective anti-cancer agents; however its use is associated with adverse cardiac effects, including cardiomyopathy and... 
Drugs | Heart | Side effects | doxorubicin, cancer drugs, side effects, cardiac, cardiotoxic effects | Treatment | Doxorubicin | Cancer
Dissertation
CARDIOVASCULAR DRUGS AND THERAPY, ISSN 0920-3206, 02/2014, Volume 28, Issue 1, pp. 19 - 32
Purpose 2-CL-IB-MECA, (A(3) adenosine receptor agonist)(A(3)AR) mediated cardioprotection is well documented although the associated intracellular signalling... 
A3 Adenosine receptor | ISCHEMIA/REPERFUSION INJURY | CARDIAC & CARDIOVASCULAR SYSTEMS | STIMULATION | BAD | Caspase | KINASE-B | Reperfusion injury | ISCHEMIA-REPERFUSION INJURY | MITOGEN-ACTIVATED PROTEIN | UROCORTIN PROTECTS | PI3K | REDUCTION | MEK1/2 | SIGNALING PATHWAY | PHARMACOLOGY & PHARMACY | CEREBRAL-ISCHEMIA | Apoptosis | AGONIST
Journal Article
Cardiovascular Drugs and Therapy, ISSN 0920-3206, 02/2014, Volume 28, Issue 1, p. 19
  2-CL-IB-MECA, (A^sub 3^ adenosine receptor agonist)(A^sub 3^AR) mediated cardioprotection is well documented although the associated intracellular signalling... 
Journal Article
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