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Circulation, ISSN 0009-7322, 08/2013, Volume 128, Issue 8, pp. 845 - 853
BACKGROUND—Proton pump inhibitors (PPIs) are gastric acid–suppressing agents widely prescribed for the treatment of gastroesophageal reflux disease. Recently,... 
dimethylarginine dimethylaminohydrolase | endothelium | proton pump inhibitors | nitric oxide | N,N dimethylarginine | N dimethylarginine | CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | ENDOTHELIAL DYSFUNCTION | MYOCARDIAL-INFARCTION | NITRIC-OXIDE SYNTHASE | ACID SUPPRESSION | ADMA | N | DIMETHYLAMINOHYDROLASE DDAH | PERIPHERAL VASCULAR DISEASE | CORONARY-HEART-DISEASE | STAGE RENAL-DISEASE | ARTERY-DISEASE | Proton Pump Inhibitors - pharmacology | Humans | Esomeprazole - adverse effects | Esomeprazole - pharmacology | Endothelium, Vascular - drug effects | Male | Arginine - analogs & derivatives | Esomeprazole - therapeutic use | Cardiovascular Diseases - epidemiology | Nitric Oxide Synthase Type III - metabolism | Gastroesophageal Reflux - drug therapy | Disease Models, Animal | Amidohydrolases - metabolism | Proton Pump Inhibitors - adverse effects | Cardiovascular Diseases - metabolism | Mice, Inbred C57BL | Risk Factors | Cells, Cultured | Biomarkers - blood | Proton Pump Inhibitors - therapeutic use | Animals | Lansoprazole - adverse effects | Endothelium, Vascular - metabolism | Arginine - blood | Lansoprazole - pharmacology | Endothelium, Vascular - pathology | Mice | Vasodilation - drug effects | Lansoprazole - therapeutic use | Gastroesophageal reflux | Complications and side effects | Usage | Care and treatment | Patient outcomes | Proton pump inhibitors | Cardiovascular diseases | Drug therapy | Health aspects | Risk factors
Journal Article
Cell Reports, ISSN 2211-1247, 05/2016, Volume 15, Issue 5, pp. 919 - 925
Journal Article
Journal Article
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 08/2015, Volume 13, Issue 1, p. 249
Background: The beneficial outcome associated with the use of proton pump inhibitors (PPIs) in idiopathic pulmonary fibrosis (IPF) has been reported in... 
Oxidative stress | Proton pump inhibitors | Inflammation | Fibrosis | MEDICINE, RESEARCH & EXPERIMENTAL | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE DDAH | ALVEOLAR EPITHELIAL-CELLS | FREE-RADICAL PRODUCTION | MESENCHYMAL TRANSITION | GASTROESOPHAGEAL-REFLUX THERAPY | CARBON-MONOXIDE | NITRIC-OXIDE | HEME OXYGENASE-1 | IDIOPATHIC PULMONARY-FIBROSIS | EXPRESSION | Idiopathic Pulmonary Fibrosis - genetics | Proton Pump Inhibitors - pharmacology | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Middle Aged | Rats, Inbred F344 | Esomeprazole - pharmacology | Male | Idiopathic Pulmonary Fibrosis - blood | Esomeprazole - therapeutic use | Lung Transplantation | Bleomycin | Female | Lung - radiation effects | Pneumonia - blood | Collagen - biosynthesis | Idiopathic Pulmonary Fibrosis - complications | Disease Models, Animal | Pneumonia - genetics | Radiation, Ionizing | Lung - pathology | Cell Separation | Solubility | Genetic Pleiotropy | Biomarkers - blood | Fibroblasts - pathology | Proton Pump Inhibitors - therapeutic use | Gene Expression Regulation - drug effects | Transforming Growth Factor beta - pharmacology | Animals | Pneumonia - drug therapy | Fibroblasts - radiation effects | Fibroblasts - drug effects | Lung - drug effects | Survival Analysis | Gene Expression Regulation - radiation effects | Idiopathic Pulmonary Fibrosis - pathology | Pneumonia - complications | Aged | Cell Proliferation - drug effects | Idiopathic Pulmonary Fibrosis - drug therapy | Cell Proliferation - radiation effects | Acute respiratory distress syndrome | Fibronectins | Medical research | Development and progression | Transforming growth factors | Antioxidants | Ionizing radiation | Interleukins | Gastrointestinal diseases | Collagen | Nitric oxide | Heme | Medicine, Experimental
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e60653
Aims: Genetic and pharmacological studies have shown that impairment of the nitric oxide (NO) synthase (NOS) pathway is associated with hypertension and... 
DIETARY-SODIUM | DIMETHYLARGININE DIMETHYLAMINOHYDROLASE DDAH | NITRIC-OXIDE SYNTHASE | EXPERIMENTAL-HYPERTENSION | MULTIDISCIPLINARY SCIENCES | ASYMMETRIC DIMETHYLARGININE | RESISTANCE | FARNESOID-X-RECEPTOR | SYNTHESIS INHIBITION | TYPE-2 DIABETES-MELLITUS | BLOOD-PRESSURE | Kidney - pathology | Cardiomegaly - etiology | Cardiomegaly - pathology | Hypertension - drug therapy | Male | Hypertension - etiology | Kidney Function Tests | Liver - drug effects | Chenodeoxycholic Acid - pharmacology | Blood Pressure - drug effects | Amidohydrolases - metabolism | Kidney - drug effects | Amidohydrolases - genetics | Liver - metabolism | Insulin Resistance | Organ Size | Rats | Chenodeoxycholic Acid - administration & dosage | Receptors, Cytoplasmic and Nuclear - agonists | Sodium Chloride, Dietary | Chenodeoxycholic Acid - analogs & derivatives | Gene Expression Regulation - drug effects | Animals | Diet | Nitric Oxide - metabolism | Hypertension | Nitric oxide | Physiological aspects | Development and progression | Insulin resistance | Genetic aspects | Research | Insulin | Risk factors | Plasma | Oxidative stress | Salts | Pressure effects | Homeostasis | Cardiovascular disease | Regulatory sequences | Blood | Toxicology | Rodents | Blood pressure | Sensitivity analysis | Pharmacology | Metabolism | Nitric-oxide synthase | Endothelium | Medicine | Sensitivity | Acids | Sensitivity enhancement | In vivo methods and tests | Diabetes | Laboratory animals
Journal Article