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Inorganic Chemistry, ISSN 0020-1669, 02/2013, Volume 52, Issue 3, pp. 1318 - 1327
Alzheimer’s disease (AD) patients show abnormally high concentrations of Cu2+ in the amyloid β plaques. This invokes that Cu2+ might play a crucial role in the... 
Journal Article
ISSN 1477-9226, 10/2017, Volume 46, Issue 39, pp. 13171 - 13175
Heme binds Aβ to give a mixture of a mono-histidine bound high spin peroxidase type active site and a bis-histidine bound low spin cytochrome b type active... 
Journal Article
Dalton transactions (Cambridge, England : 2003), ISSN 1477-9226, 06/2019, Volume 48, Issue 21, pp. 7451 - 7461
A significant abundance of copper (Cu) and iron in amyloid β (Aβ) plaques, and several heme related metabolic disorders are directly correlated with... 
Journal Article
ISSN 1477-9226, 5/2019, Volume 48, Issue 21, pp. 7451 - 7461
A significant abundance of copper (Cu) and iron in amyloid β (Aβ) plaques, and several heme related metabolic disorders are directly correlated with... 
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 02/2016, Volume 55, Issue 4, pp. 1748 - 1757
Recent evidence has established the colocalization of amyloid-rich plaques and heme-rich deposits in the human cerebral cortex as a common postmortem feature... 
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 02/2016, Volume 55, Issue 4, pp. 1748 - 1757
Journal Article
ISSN 1359-7345, 5/2013, Volume 49, Issue 51, pp. 5754 - 5756
Partially reduced oxygen species (PROS), produced by reduced heme bound A peptides, can cause oxidative stress and synaptic damage in the brain, which is one... 
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 09/2015, Volume 48, Issue 9, pp. 2556 - 2564
Redox active iron is utilized in biology for various electron transfer and catalytic reactions essential for life, yet this same chemistry mediates the... 
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 09/2015, Volume 48, Issue 9, p. 2556
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 36, pp. 8405 - 8410
Proteolysis of Amyloid Precursor Protein, APP, results in the formation of amyloid β (Aβ) peptides, which have been associated with Alzheimer's disease (AD).... 
Degradation | Neurotransmitters | Peptides | Serotonin | Reaction kinetics | Homeostasis | Peroxidase | Pharmacology | Alzheimers disease | Chemical compounds | Alzheimer's disease
Journal Article
JBIC Journal of Biological Inorganic Chemistry, ISSN 0949-8257, 09/2016, Volume 21, Issue 5-6, p. 683
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00775-016-1367-6 Heme... 
Cytochrome c | Hydrogen peroxide | Peptides | Heme | Peroxidase | Alzheimer's disease
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2011, Volume 133, Issue 39, pp. 15545 - 15552
Recently, it has been shown that heme binds to Aβ peptides which may play a major role in Alzheimer’s disease (AD). This study illustrates that Aβ peptides can... 
Journal Article
Coordination Chemistry Reviews, ISSN 0010-8545, 01/2013, Volume 257, Issue 1, pp. 81 - 92
► His of Aβ peptide binds heme. ► The Arg residue H-bonds with the axial water ligand of heme-Aβ, lowering its p and making heme-Aβ complexes function as... 
Spectroscopy | Aβ peptide | Absorption | Reactivity | EPR | Heme | Therapeutics | Alzheimer's disease | OXIDATIVE STRESS | LIPID-PEROXIDATION | COPPER | ANTIOXIDANT PROPERTIES | CHEMISTRY, INORGANIC & NUCLEAR | CYTOCHROME-C-OXIDASE | IN-VITRO | ZINC-BINDING SITE | A-BETA | HYDROGEN-PEROXIDE | A beta peptide | AMINE OXIDASE
Journal Article
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