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Frontiers in Pharmacology, ISSN 1663-9812, 2014, Volume 5, p. 124
Iron regulatory proteins (IRPs) regulate the expression of genes involved in iron metabolism by binding to RNA stem-loop structures known as iron responsive... 
Erythropoiesis | Iron regulatory protein | Iron metabolism | Polycythemia | Pulmonary hypertension | Iron responsive element | iron metabolism | iron responsive element | pulmonary hypertension
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2016, Volume 22, Issue 2, pp. 163 - 174
Chronic obstructive pulmonary disease (COPD) is linked to both cigarette smoking and genetic determinants. We have previously identified iron-responsive... 
MEDICINE, RESEARCH & EXPERIMENTAL | REGULATORY PROTEIN-2 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFICIENCY | CELL BIOLOGY | CYTOCHROME-C-OXIDASE | LUNG-CANCER | OBSTRUCTIVE PULMONARY-DISEASE | GENE-EXPRESSION | ANEMIA | TARGETED DELETION | GENOME-WIDE ASSOCIATION | COPD | Immunohistochemistry | Smoking - adverse effects | Immunoprecipitation | Pulmonary Emphysema - etiology | Bronchitis - genetics | Humans | Immunoblotting | Gene Expression Profiling | Iron, Dietary | Pulmonary Disease, Chronic Obstructive - etiology | Lung Injury - etiology | Electron Transport Complex IV - metabolism | Flow Cytometry | Membrane Potential, Mitochondrial | Pulmonary Emphysema - genetics | Aged, 80 and over | Electrophoretic Mobility Shift Assay | Lung - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Pneumonia - genetics | Pulmonary Disease, Chronic Obstructive - genetics | Microscopy, Electron, Transmission | Pneumonia - etiology | Enzyme-Linked Immunosorbent Assay | Smoke - adverse effects | Bronchitis - etiology | Mitochondria - metabolism | Mitochondria - drug effects | Mucociliary Clearance - genetics | Iron - metabolism | Mice, Knockout | Airway Remodeling | Microscopy, Confocal | Lung Injury - genetics | Tobacco | Animals | Iron Chelating Agents - pharmacology | Iron Regulatory Protein 2 - genetics | Lung - drug effects | Iron-Binding Proteins - genetics | Aged | Mice | Iron Regulatory Protein 2 - metabolism | Microscopy, Fluorescence | Molecular targeted therapy | Care and treatment | Emphysema, Pulmonary | Patient outcomes | Genetic aspects | Bronchitis | Health aspects | Chelation therapy | Cigarette smoke | Methods | Mitochondria | Iron | Emphysema | Rodents | Smoking | IRP2 | Lung
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e57919
Journal Article
Pharmacognosy Magazine, ISSN 0973-1296, 10/2017, Volume 13, Issue 52, pp. 780 - 785
Background: To date, efforts for the prevention and treatment of human respiratory syncytial virus (RSV) infection have been still vain, and there is no safe... 
Apigenin-6 | 8-di-C-β-D-galactoside | Arisaema | Schaftoside | Rutin | ProTox | Studies | Proteins | Researchers | Respiratory syncytial virus | Metabolites | Ligands | Metabolism | Pharmaceutical sciences | Original
Journal Article
Journal Article
Science, ISSN 0036-8075, 03/2018, Volume 359, Issue 6383, pp. 1520 - 1523
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2015, Volume 5, Issue 1, p. 8711
With the aim to capture and subsequent selective trapping of CO2, a nanocomposite has been developed through selective modification of the outer surface of the... 
NANOPARTICLES | CLAY NANOTUBES | CARBON-DIOXIDE CAPTURE | KINETICS | MULTIDISCIPLINARY SCIENCES | CONTROLLED-RELEASE | AMBIENT AIR | FRAMEWORK | ADSORBENT | FLUE-GAS | ADSORPTION | Spectroscopy | Nanocomposites | Adsorption | Temperature preferences | Temperature effects | Carbon dioxide | Nanotubes | Isotopes
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 08/2013, Volume 305, Issue 3, pp. L222 - L228
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2011, Volume 6, Issue 10, p. e25404
Genetic ablation of Iron Regulatory Protein 2 (Irp2, Ireb2), which post-transcriptionally regulates iron metabolism genes, causes a gait disorder in mice that... 
NEURODEGENERATIVE DISEASE | HOMEOSTASIS | REGULATORY PROTEIN-2 | TRANSFERRIN RECEPTOR | H-FERRITIN | TDP-43 | DEFICIENT | BIOLOGY | AMYOTROPHIC-LATERAL-SCLEROSIS | TARGETED DELETION | KNOCKOUT MICE | Spinal Cord - drug effects | Spinal Cord - metabolism | Spin Labels | Motor Neurons - pathology | Brain - metabolism | Mitochondria - genetics | Cyclic N-Oxides - pharmacology | Spinal Cord - pathology | Gene Deletion | Iron - deficiency | Homeostasis - drug effects | Motor Neurons - drug effects | Biomarkers - metabolism | Iron Regulatory Protein 2 - deficiency | Oxidative Stress - genetics | Axons - drug effects | Axons - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Iron - metabolism | Iron Regulatory Protein 1 - deficiency | Brain - drug effects | Motor Neurons - metabolism | Apoferritins - biosynthesis | Animals | Iron Regulatory Protein 1 - metabolism | Iron Regulatory Protein 2 - genetics | Axons - pathology | Brain - pathology | Mice | Oxidative Stress - drug effects | Atrophy - metabolism | Homeostasis - genetics | Physiological aspects | Neurons | Ferritin | Blood proteins | Iron regulatory protein | Post-transcription | Spinal cord | Transferrin | Gait | Childrens health | Homeostasis | Tempol | Homology | Iron | Proteins | Electron transport chain | Mitochondria | Neurodegeneration | Rodents | Degeneration | Paralysis | Copper | Motor neurons | Starvation | Nutrient deficiency | Cell survival | Amyotrophic lateral sclerosis | Metabolism | Ablation | Storage proteins | Axons | Mutation | Endoplasmic reticulum
Journal Article
Cell Metabolism, ISSN 1550-4131, 02/2013, Volume 17, Issue 2, pp. 271 - 281
Journal Article